List of works by Marius Wernig

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

scientific article (publication date: 21 April 2006)

A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry

scientific article

A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

scientific article published on July 2008

Acute reduction in oxygen tension enhances the induction of neurons from human fibroblasts

scientific article

An imprinted signature helps isolate ESC-equivalent iPSCs

scientific article

An indirect approach to generating specific human cell types

scientific article

Analysis of conditional heterozygous STXBP1 mutations in human neurons

scientific article

ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion

scientific article published on 18 January 2017

Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons

scientific article

CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming

scientific article published on 11 October 2018

Calcineurin signaling regulates neural induction through antagonizing the BMP pathway

scientific article published on April 2014

Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility.

scientific article published in July 2009

Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

scientific article published on 31 March 2020

Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells.

scientific article published on 6 April 2010

Comprehensive qPCR profiling of gene expression in single neuronal cells

scientific article

Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease.

scientific article

Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation

scientific article published on 21 March 2016

Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation.

scientific article published in March 2016

Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells

scientific article (publication date: 8 August 2008)

Corrigendum: Failure to replicate the STAP cell phenomenon

scientific article published on 16 December 2015

Corrigendum: Hallmarks of pluripotency

correction of a scholarly article

Crosstalk between stem cell and cell cycle machineries

scientific article

Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk

scientific article published on 22 July 2019

Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity

scientific article published on 30 May 2019

Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

Direct conversion of fibroblasts to functional neurons by defined factors

scientific article

Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells

scientific article

Direct lineage conversion of terminally differentiated hepatocytes to functional neurons

scientific article

Direct lineage conversions: unnatural but useful?

scientific article

Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells

scientific article published on 27 August 2007

Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency

scientific article

Direct somatic lineage conversion

scientific article published on October 2015

Direct targeting of the mouse optic nerve for therapeutic delivery

scientific article published on 31 October 2018

Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq

scientific article published on 08 June 2016

Early reprogramming regulators identified by prospective isolation and mass cytometry

scientific article published on April 2015

FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis.

scientific article published on 25 July 2013

Failure to replicate the STAP cell phenomenon

scientific article published in September 2015

Fifty ways to make a neuron: shifts in stem cell hierarchy and their implications for neuropathology and CNS repair

scientific article

FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice

scientific article published on 11 July 2016

Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro

scientific article

Functional integration of embryonic stem cell-derived neurons in hippocampal slice cultures.

scientific article published in August 2003

Functional integration of embryonic stem cell-derived neurons in vivo.

scientific article published in June 2004

Generation of iPSCs from cultured human malignant cells

scientific article

Generation of induced neuronal cells by the single reprogramming factor ASCL1

scientific article

Generation of oligodendroglial cells by direct lineage conversion.

scientific article

Generation of pure GABAergic neurons by transcription factor programming

scientific article published on 15 May 2017

Genome-scale DNA methylation maps of pluripotent and differentiated cells

scientific article

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

scientific article

Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons

scientific article published on 15 January 2019

Hallmarks of pluripotency

scientific article published on September 2015

Harnessing the stem cell potential: a case for neural stem cell therapy

scientific article published in December 2013

Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing

scientific article published on 23 October 2019

Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons

scientific article

Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.

scientific article published on 26 December 2016

Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa

scientific article published on November 2014

Human Neuropsychiatric Disease Modeling using Conditional Deletion Reveals Synaptic Transmission Defects Caused by Heterozygous Mutations in NRXN1.

scientific article published on 12 August 2015

In Vitro Modeling of the Bipolar Disorder and Schizophrenia Using Patient-Derived Induced Pluripotent Stem Cells with Copy Number Variations of PCDH15 and RELN

scientific article published on 01 September 2019

In Vivo Reprogramming for Brain and Spinal Cord Repair

scientific article

In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases

scientific article published on November 2011

Induced neuronal cells: how to make and define a neuron

scientific article

Induced neuronal reprogramming

scientific article

Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model

scientific article

Induction of human neuronal cells by defined transcription factors

scientific article

Migration and differentiation of myogenic precursors following transplantation into the developing rat brain

scientific article published on January 2003

Modeling Alzheimer's disease with human iPS cells: advancements, lessons, and applications

scientific article published on 13 June 2019

Molecular roadblocks for cellular reprogramming

scientific article

Myeloid cell replacement is neuroprotective in chronic experimental autoimmune encephalomyelitis

scientific article published on 21 March 2024

Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates

scientific article

Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons

scientific article published on 27 June 2019

Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation

scientific article

New Approaches, New Opportunities at the 2019 ISSCR Annual Meeting

Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation

scientific article published on 01 October 2019

On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010.

scientific article published in October 2010

Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons.

scientific article

Polycomb complexes repress developmental regulators in murine embryonic stem cells

scientific article (publication date: 18 May 2006)

Pro-neuronal activity of Myod1 due to promiscuous binding to neuronal genes

scientific article published on 30 March 2020

Profiling DNA-transcription factor interactions

scientific article published on 01 June 2018

Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons

scientific article published on September 2017

Rapid single-step induction of functional neurons from human pluripotent stem cells

scientific article

Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells

scientific article

TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment

scientific article published on 24 January 2019

Tau EGFP embryonic stem cells: An efficient tool for neuronal lineage selection and transplantation

scientific article published on 01 September 2002

Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells

scientific article

The fragile X mutation impairs homeostatic plasticity in human neurons by blocking synaptic retinoic acid signaling

scientific article published on 01 August 2018

The histone chaperone CAF-1 safeguards somatic cell identity

scientific article

The many roads to Rome: induction of neural precursor cells from fibroblasts

scientific article

The novel lncRNA is pro-neurogenic and mutated in human neurodevelopmental disorders

scientific article published on 10 January 2019

The novel tool of cell reprogramming for applications in molecular medicine

scientific article

The vast majority of bone-marrow-derived cells integrated into mdx muscle fibers are silent despite long-term engraftment

scientific article

Transdifferentiation of human adult peripheral blood T cells into neurons

scientific article published on 04 June 2018

Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties

scientific article published on 08 June 2017

c-Myc is dispensable for direct reprogramming of mouse fibroblasts.

scientific article

m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells

scientific article

μNeurocircuitry: Establishing in vitro models of neurocircuits with human neurons.

scientific article published in June 2017

Paulina is supported by:

About Paulina

Help