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List of works by Margherita Sosio

A Derivative of the Thiopeptide GE2270A Highly Selective against Propionibacterium acnes

scientific article published on 18 May 2015

A Genomic, Transcriptomic and Proteomic Look at the GE2270 Producer Planobispora rosea, an Uncommon Actinomycete

scientific article published on 24 July 2015

A Two-Component regulatory system with opposite effects on glycopeptide antibiotic biosynthesis and resistance

scientific article published on 10 April 2020

A biaryl-linked tripeptide from Planomonospora reveals a widespread class of minimal RiPP gene clusters ⬇️

scientific article published on 10 December 2020

A community resource for paired genomic and metabolomic data mining

scientific article published in 2021

A derivative of the glycopeptide A40926 produced by inactivation of the beta-hydroxylase gene in Nonomuraea sp. ATCC39727.

scientific article published in March 2006

A gene transfer system for the glycopeptide producer Nonomuraea sp. ATCC39727.

scientific article published in August 2003

A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity.

scientific article published on 20 November 2013

Actinospica robiniae gen. nov., sp. nov. and Actinospica acidiphila sp. nov.: proposal for Actinospicaceae fam. nov. and Catenulisporinae subord. nov. in the order Actinomycetales.

scientific article

Advancing cell wall inhibitors towards clinical applications

scientific article

Allocyclinones, hyperchlorinated angucyclinones from Actinoallomurus ⬇️

scientific article published on 25 May 2016

Allopeptimicins: unique antibacterial metabolites generated by hybrid PKS-NRPS, with original self-defense mechanism in Actinoallomurus† † Electronic supplementary information (ESI) available. See https://doi.org/10.1039/d2ra02094g

scientific article published on 06 June 2022

Analysis of the Pseudouridimycin Biosynthetic Pathway Provides Insights into the Formation of C-nucleoside Antibiotics ⬇️

scientific article published on 15 March 2018

Antibacterial Aromatic Polyketides Incorporating the Unusual Amino Acid Enduracididine ⬇️

scientific article published on 07 January 2019

Antibacterial Paramagnetic Quinones from Actinoallomurus.

scientific article published on 20 February 2017

Antibiotic discovery in the twenty-first century: current trends and future perspectives

scientific article

Antibiotic-producing ability by representatives of a newly discovered lineage of actinomycetes.

scientific article published in March 2006

Antibiotics GE23077, novel inhibitors of bacterial RNA polymerase. Part 3: Chemical derivatization.

scientific article published in August 2005

Artificial chromosome libraries of Streptomyces coelicolor A3(2) and Planobispora rosea

scientific article

Bacterial discrimination by means of a universal array approach mediated by LDR (ligase detection reaction).

scientific article

Biosynthesis of glycopeptides: prospects for improved antibacterials

scientific article published on January 2008

Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain ⬇️

scientific article published on 12 March 2021

Brominated Variant of the Lantibiotic NAI-107 with Enhanced Antibacterial Potency.

scientific article published on 29 October 2015

Capturing linear intermediates and C-terminal variants during maturation of the thiopeptide GE2270.

scientific article published on 8 August 2013

Catenulispora acidiphila gen. nov., sp. nov., a novel, mycelium-forming actinomycete, and proposal of Catenulisporaceae fam. nov.

scientific article

Challenges and advances in genetic manipulation of filamentous actinomycetes - the remarkable producers of specialized metabolites

scientific article published on 13 September 2019

Chapter 1. Approaches to discovering novel antibacterial and antifungal agents

scientific article published on 01 January 2009

Characterization of madurastatin C1, a novel siderophore from Actinomadura sp

scientific article published on 29 February 2012

Characterization of the congeners in the lantibiotic NAI-107 complex

scientific article published on 14 January 2014

Chrolactomycins from the actinomycete actinospica.

scientific article

Comparative analysis and insights into the evolution of gene clusters for glycopeptide antibiotic biosynthesis.

scientific article published on 9 July 2005

Complex Regulatory Networks Governing Production of the Glycopeptide A40926.

scientific article published on 5 April 2018

Discovering new bioactive molecules from microbial sources.

scientific article published on 24 March 2014

Discovery, properties, and biosynthesis of pseudouridimycin, an antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase

scientific article published on 21 November 2018

Diversity of Actinoplanes and Related Genera Isolated from an Italian Soil ⬇️

scientific article published on April 22, 2003

Draft Genome Sequence of the Microbispora sp. Strain ATCC-PTA-5024, Producing the Lantibiotic NAI-107

scientific article published on 23 January 2014

Editorial: XXXIII SIMGBM Congress 2019 - Environmental and Industrial Microbiology

scientific article published in 2021

Effective approaches to discover new microbial metabolites in a large strain library

scientific article published on 18 February 2021

Elucidating the molecular physiology of lantibiotic NAI-107 production in Microbispora ATCC-PTA-5024.

scientific article published on 12 January 2016

Expanding the potential of NAI-107 for treating serious ESKAPE pathogens: synergistic combinations against Gram-negatives and bactericidal activity against non-dividing cells

scientific article published on 30 October 2017

Glycopeptide resistance determinants from the teicoplanin producer Actinoplanes teichomyceticus

scientific article published in November 2004

Halogenated Spirotetronates from Actinoallomurus

scientific article published on 22 May 2012

Heterologous expression of the thiopeptide antibiotic GE2270 from Planobispora rosea ATCC 53733 in Streptomyces coelicolor requires deletion of ribosomal genes from the expression construct.

scientific article

Identification of the Entner-Doudoroff pathway in an antibiotic-producing actinomycete species.

scientific article published in May 2004

Identification of two linear plasmids in the actinomycete Planobispora rosea ⬇️

scientific article published on October 1, 1998

Impact of the first Streptomyces genome sequence on the discovery and production of bioactive substances.

scientific article

Improved production of A40926 by Nonomuraea sp. through deletion of a pathway-specific acetyltransferase.

scientific article published on 23 April 2010

Inorganic phosphate is a trigger factor for Microbispora sp. ATCC-PTA-5024 growth and NAI-107 production

scientific article published on 10 October 2014

Insights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster.

scientific article

Isolation of high molecular weight DNA from soil for cloning into BAC vectors.

scientific article

Large inserts for big data: artificial chromosomes in the genomic era

scientific article published on 01 May 2018

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

scientific article published on 9 December 2024

Microbial technologies for the discovery of novel bioactive metabolites.

scientific article

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

Molecular and phenotypic traits of in-vitro-selected mutants of Bifidobacterium resistant to rifaximin.

scientific article published on 6 May 2008

Multi-omics Study of Planobispora rosea, Producer of the Thiopeptide Antibiotic GE2270A

scientific article published on 22 June 2021

New PCR primers for the selective amplification of 16S rDNA from different groups of actinomycetes

scientific article published on 01 December 2002

New lineage of filamentous, spore-forming, gram-positive bacteria from soil

scientific article

Novel Polyethers from Screening Actinoallomurus spp. ⬇️

scientific article

Novel assays and novel strains - promising routes to new antibiotics?

scientific article published on 01 June 2007

Novel members of the family Micromonosporaceae, Rugosimonospora acidiphila gen. nov., sp. nov. and Rugosimonospora africana sp. nov.

scientific article published on 22 July 2009

Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.

scientific article published on January 2004

Planomonospora: A Metabolomics Perspective on an Underexplored Actinobacteria Genus ⬇️

scientific article published on 26 January 2021

Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics

scientific article published on 10 May 2007

Reclassification as a Nonomuraea sp. of the strain ATCC 39727, producing the glycopeptide antibiotic A40926.

scientific article published in January 2004

Ribonuclease P RNA gene sequencing as a tool for molecular dereplication of myxobacterial strain collections.

scientific article

Sources of novel antibiotics--aside the common roads

scientific article published on 24 September 2010

Strategies for combinatorial biosynthesis with modular polyketide synthases.

scientific article published on September 2003

Structure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis

scientific article published on 8 February 2016

Structure revision of the lantibiotic 97518.

scientific article published in April 2009

Targets and assays for discovering novel antibacterial agents.

scientific article

The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions

scientific article

The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species

scientific article published on June 2003

The genus Actinoallomurus and some of its metabolites.

scientific article published in December 2010

Toward Single-Peak Dalbavancin Analogs through Biology and Chemistry

scientific article published on 07 March 2019

Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis

scientific article

Two Master Switch Regulators Trigger A40926 Biosynthesis in Nonomuraea sp. Strain ATCC 39727.

scientific article published on 18 May 2015

Understanding and manipulating glycopeptide pathways: the example of the dalbavancin precursor A40926.

scientific article published on 26 April 2006

Validation for high-throughput screening of a VanRS-based reporter gene assay for bacterial cell wall inhibitors

scientific article published on 01 July 2007

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