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List of works by Craig E. Cameron

5'-triphosphate-dependent activation of PKR by RNAs with short stem-loops

scientific article published on November 2007

A Polymerase Mechanism-based Strategy for Viral Attenuation and Vaccine Development ⬇️

scientific article published on September 14, 2012

A naturally occurring antiviral ribonucleotide encoded by the human genome

scientific article published in Nature

Accurate nanoscale flexibility measurement of DNA and DNA-protein complexes by atomic force microscopy in liquid

scientific article published in August 2017

Acoustofluidic Transfer of Inflammatory Cells from Human Sputum Samples

scientific article

Acoustofluidic bacteria separation

scientific article published on 30 November 2016

Amiloride is a competitive inhibitor of coxsackievirus B3 RNA polymerase

scientific article published on 27 July 2011

An on-chip, multichannel droplet sorter using standing surface acoustic waves

scientific article

Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M 1 dG ⬇️

scientific article published on July 29, 2010

Binding by the hepatitis C virus NS3 helicase partially melts duplex DNA.

scientific article published on 13 September 2012

Biochemical and genetic analysis of the role of the viral polymerase in enterovirus recombination

scientific article published on 17 June 2016

Challenges for the development of ribonucleoside analogues as inducers of error catastrophe

scientific article published on January 2004

Computational Analysis of Amiloride Analogue Inhibitors of Coxsackievirus B3 RNA Polymerase

scientific article

Conformational Ensemble of the Poliovirus 3CD Precursor Observed by MD Simulations and Confirmed by SAXS: A Strategy to Expand the Viral Proteome?

scientific article published on 23 November 2015

Control of template positioning during de novo initiation of RNA synthesis by the bovine viral diarrhea virus NS5B polymerase

scientific article published on 29 June 2006

Correlation between NS5A dimerization and hepatitis C virus replication

scientific article published on 16 July 2012

Crystal Structure of Poliovirus 3CD Protein: Virally Encoded Protease and Precursor to the RNA-Dependent RNA Polymerase

scientific article

Cystoviral polymerase complex protein P7 uses its acidic C-terminal tail to regulate the RNA-directed RNA polymerase P2.

scientific article published on 9 May 2014

Cytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering the nucleus and interfering with Prp8

scientific article

Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin

scientific article published on October 2008

Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase?

scientific article

Effects of BMS-986094, a Guanosine Nucleotide Analogue, on Mitochondrial DNA Synthesis and Function

scientific article published on 27 July 2016

Effects of introduction of hydrophobic group on ribavirin base on mutation induction and anti-RNA viral activity

scientific article published on 8 December 2007

Expanding knowledge of P3 proteins in the poliovirus lifecycle

scientific article published on June 2010

Exploring the Dynamics of Four RNA-Dependent RNA Polymerases by a Coarse-Grained Model ⬇️

scientific article published on December 7, 2012

Expression and Purification of Mitochondrial RNA Polymerase and Transcription Factor A from Drosophila melanogaster

scientific article published on January 2016

Extended-Spectrum Beta-Lactamase Infections in Orthopedic-Related Devices and Prosthetic Joints

scientific article published on 10 June 2016

Foot-and-mouth disease virus type O specific mutations determine RNA-dependent RNA polymerase fidelity and virus attenuation

scientific article published on 15 February 2018

HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors

scientific article published on 3 April 2010

Hepatitis C virus NS3 and simian virus 40 T antigen helicases displace streptavidin from 5'-biotinylated oligonucleotides but not from 3'-biotinylated oligonucleotides: evidence for directional bias in translocation on single-stranded DNA.

scientific article

Hepatitis C virus non-structural protein 3 (HCV NS3): a multifunctional antiviral target

scientific article

Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein

scientific article

Hepatitis C virus nonstructural protein 5A: biochemical characterization of a novel structural class of RNA-binding proteins

scientific article

Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein.

scientific article

Human Mitochondrial RNA Polymerase: Evaluation of the Single-Nucleotide-Addition Cycle on Synthetic RNA/DNA Scaffolds ⬇️

scientific article published on May 12, 2011

Human mitochondrial RNA polymerase: Structure–function, mechanism and inhibition ⬇️

scientific article published on April 19, 2012

Human rhinovirus type 14 gain-of-function mutants for oriI utilization define residues of 3C(D) and 3Dpol that contribute to assembly and stability of the picornavirus VPg uridylylation complex

scientific article

Identification of multiple rate-limiting steps during the human mitochondrial transcription cycle in vitro

scientific article

Incorporation fidelity of the viral RNA-dependent RNA polymerase: a kinetic, thermodynamic and structural perspective

scientific article

Inhibition of dengue virus replication by mycophenolic acid and ribavirin

scientific article

Insight into poliovirus genome replication and encapsidation obtained from studies of 3B-3C cleavage site mutants

scientific article published on 8 July 2009

Interferon and ribavirin combination treatment synergistically inhibit HCV internal ribosome entry site mediated translation at the level of polyribosome formation

scientific article

Intermolecular Interactions within the Abundant DEAD-box Protein Dhh1 Regulate Its Activity in Vivo ⬇️

scientific article published on June 3, 2011

Investigation of Translocation, DNA Unwinding, and Protein Displacement by NS3h, the Helicase Domain from the Hepatitis C Virus Helicase

scientific article

Isolation of enzymatically active replication complexes from feline calicivirus-infected cells

scientific article

Kinetic analysis of human PrimPol DNA polymerase activity reveals a generally error-prone enzyme capable of accurately bypassing 7,8-dihydro-8-oxo-2'-deoxyguanosine

scientific article published on 10 October 2014

Lethal mutagens: broad-spectrum antivirals with limited potential for development of resistance?

scientific article published on February 2004

Long-Range Communication between Different Functional Sites in the Picornaviral 3C Protein

scientific article published on April 2016

Manganese-Dependent Polioviruses Caused by Mutations within the Viral Polymerase ⬇️

scientific article published on May 1, 2003

Mechanisms of action of ribavirin against distinct viruses

scientific article

Melting of Duplex DNA in the Absence of ATP by the NS3 Helicase Domain through Specific Interaction with a Single-Strand/Double-Strand Junction

scientific article published on 02 July 2015

Microfluidic opportunities in the field of nutrition

scientific article

Molecular Dynamics Simulations of Viral RNA Polymerases Link Conserved and Correlated Motions of Functional Elements to Fidelity ⬇️

scientific article published on May 7, 2011

More than efficacy revealed by single-cell analysis of antiviral therapeutics

scientific article published on 30 October 2019

Motif D of Viral RNA-Dependent RNA Polymerases Determines Efficiency and Fidelity of Nucleotide Addition ⬇️

scientific article published on July 19, 2012

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer

scientific article published on 31 August 2016

Multicentre study of the clinical relevance of screening IVF patients for carrier status of the annexin A5 M2 haplotype

scientific article published on 12 April 2014

Multiple full-length NS3 molecules are required for optimal unwinding of oligonucleotide DNA in vitro

scientific article

Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides.

scientific article published on 27 April 2018

Mutagen resistance and mutation restriction of St. Louis encephalitis virus.

scientific article published on February 2017

Mutational robustness of an RNA virus influences sensitivity to lethal mutagenesis

scientific article published on 21 December 2011

NS3 Helicase from the Hepatitis C Virus Can Function as a Monomer or Oligomer Depending on Enzyme and Substrate Concentrations

scientific article

Native tertiary structure and nucleoside modifications suppress tRNA's intrinsic ability to activate the innate immune sensor PKR.

scientific article

Norovirus proteinase-polymerase and polymerase are both active forms of RNA-dependent RNA polymerase

scientific article

Nucleic acid polymerases use a general acid for nucleotidyl transfer

scientific article published on 18 January 2009

Nucleobase but not Sugar Fidelity is Maintained in the Sabin I RNA-Dependent RNA Polymerase

scientific article published on 26 October 2015

One-pot synthesis of nucleoside 5'-triphosphates from nucleoside 5'-H-phosphonates

scientific article

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions

scientific article published on 27 July 2017

Phosphate release contributes to the rate-limiting step for unwinding by an RNA helicase

scientific article

Picornavirus genome replication. Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structural model for the PV 3C2-3Dpol complex

scientific article

Picornavirus genome replication: assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complex

scientific article

Picornavirus genome replication: roles of precursor proteins and rate-limiting steps in oriI-dependent VPg uridylylation

scientific article

Pleiotropic mechanisms of ribavirin antiviral activities

scientific article

Poliovirus RNA-dependent RNA polymerase (3Dpol): kinetic, thermodynamic, and structural analysis of ribonucleotide selection

scientific article published on May 2004

Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2+.

scientific article published on May 2004

Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mn2+.

scientific article published on May 2004

Poliovirus infection transiently increases COPII vesicle budding

scientific article

Polymerase Mechanism-Based Method of Viral Attenuation

scientific article

Publisher Correction: A naturally occurring antiviral ribonucleotide encoded by the human genome

scientific article published in Nature

Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli

scientific article published on September 2004

Quasispecies, error catastrophe, and the antiviral activity of ribavirin

scientific article

RNA unwinding activity of the hepatitis C virus NS3 helicase is modulated by the NS5B polymerase

scientific article published on 8 January 2008

RNA virus population diversity, an optimum for maximal fitness and virulence

scientific article

Regulation of PKR by HCV IRES RNA: importance of domain II and NS5A

scientific article

Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase

scientific article

Ribavirin's antiviral mechanism of action: lethal mutagenesis?

scientific article

Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides

scientific article

Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes

scientific article (publication date: June 2015)

Single-Cell Virology: On-Chip Investigation of Viral Infection Dynamics

scientific article published in November 2017

Small ubiquitin-like modifying protein isopeptidase assay based on poliovirus RNA polymerase activity

scientific article

Standing surface acoustic wave based cell coculture

scientific article

Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro

scientific article

Stimulation of poliovirus synthesis in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro

scientific article

Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus

scientific article

Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis

scientific article published on January 2006

Structural models of mammalian mitochondrial transcription factor B2.

scientific article

Structure-function analysis of vaccinia virus H7 protein reveals a novel phosphoinositide binding fold essential for poxvirus replication

scientific article

Structure-function relationships among RNA-dependent RNA polymerases

scientific article

Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation.

scientific article

Structure-function relationships of the viral RNA-dependent RNA polymerase: fidelity, replication speed, and initiation mechanism determined by a residue in the ribose-binding pocket

scientific article

Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.

scientific article

Synthesis of a universal 5-nitroindole ribonucleotide and incorporation into RNA by a viral RNA-dependent RNA polymerase

scientific article published on August 2007

The 3' untranslated regions of influenza genomic sequences are 5'PPP-independent ligands for RIG-I

scientific article

The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent

scientific article published on 29 October 2009

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family

scientific article

The RNA-Binding Site of Poliovirus 3C Protein Doubles as a Phosphoinositide-Binding Domain

scientific article published in December 2017

The RNA-binding site of poliovirus 3C protein doubles as a phosphoinositide-binding domain

scientific article published on 05 August 2017

The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts

scientific article published on 29 January 2018

The palm subdomain-based active site is internally permuted in viral RNA-dependent RNA polymerases of an ancient lineage

scientific article published in November 2002

Therapeutically targeting RNA viruses via lethal mutagenesis

scientific article

Transcription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitro ⬇️

scientific article (publication date: 24 April 2012)

Triphosphate Reorientation of the Incoming Nucleotide as a Fidelity Checkpoint in Viral RNA-dependent RNA Polymerases

scientific article published on 18 January 2017

Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases

scholarly article

Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter.

scientific article published on 26 July 2017

Vaccine-derived mutation in motif D of poliovirus RNA-dependent RNA polymerase lowers nucleotide incorporation fidelity

scientific article published on 30 September 2013

Viral reorganization of the secretory pathway generates distinct organelles for RNA replication

scientific article

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