List of works - Amy M Pooler

A role for tau at the synapse in Alzheimer's disease pathogenesis.

scientific article published on 25 September 2013

A systems approach to personalised nutrition: Report on the Keystone Symposium "Human Nutrition, Environment and Health".

scientific article published on 4 August 2016

Advances in tau-based drug discovery.

scientific article

Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease

scientific article

Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture.

scientific article

Copines-1, -2, -3, -6 and -7 show different calcium-dependent intracellular membrane translocation and targeting

scientific article

Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease

scientific article published on 18 May 2016

Dietary uridine-5'-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats.

scientific article published on January 2005

Effect of a 5-HT(2C) serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs.

scientific article

Functional implications of the association of tau with the plasma membrane.

scientific article published on August 2010

Identification of a novel region of the GABA(B2) C-terminus that regulates surface expression and neuronal targeting of the GABA(B) receptor.

scientific article published on March 2009

Inside Alzheimer brain with CLARITY: senile plaques, neurofibrillary tangles and axons in 3-D.

scientific article

Intracellular and extracellular roles for tau in neurodegenerative disease.

scientific article published on January 2014

Lateral diffusion of the GABAB receptor is regulated by the GABAB2 C terminus.

scientific article published on 27 June 2007

Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures.

scientific article published on 16 March 2017

Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice.

scientific article published on 7 December 2015

Physiological release of endogenous tau is stimulated by neuronal activity.

scientific article published on 15 February 2013

Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets

scientific article published on 23 October 2013

Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia.

scientific article

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons

scientific article published on 9 October 2015

Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity

scientific article

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model

scientific article

Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease

scientific article

Studying synapses in human brain with array tomography and electron microscopy

scientific article

Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology

scientific article published on December 2013

The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons.

scientific article published on 29 March 2006

The intersection of amyloid β and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease.

scientific article published on 22 March 2013

Uridine enhances neurite outgrowth in nerve growth factor-differentiated PC12 [corrected]

scientific article published in January 2005

List of works by Amy M Pooler

A role for tau at the synapse in Alzheimer's disease pathogenesis.

A systems approach to personalised nutrition: Report on the Keystone Symposium "Human Nutrition, Environment and Health".

Advances in tau-based drug discovery.

Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease

Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture.

Copines-1, -2, -3, -6 and -7 show different calcium-dependent intracellular membrane translocation and targeting

Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease

Dietary uridine-5'-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats.

Effect of a 5-HT(2C) serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs.

Functional implications of the association of tau with the plasma membrane.

Identification of a novel region of the GABA(B2) C-terminus that regulates surface expression and neuronal targeting of the GABA(B) receptor.

Inside Alzheimer brain with CLARITY: senile plaques, neurofibrillary tangles and axons in 3-D.

Intracellular and extracellular roles for tau in neurodegenerative disease.

Lateral diffusion of the GABAB receptor is regulated by the GABAB2 C terminus.

Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures.

Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice.

Physiological release of endogenous tau is stimulated by neuronal activity.

Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets

Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia.

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons

Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model

Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease

Studying synapses in human brain with array tomography and electron microscopy

Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology

The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons.

The intersection of amyloid β and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease.

Uridine enhances neurite outgrowth in nerve growth factor-differentiated PC12 [corrected]