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List of works by Ignacio I Wistuba

18F-fluorodeoxyglucose positron emission tomography correlates with tumor immunometabolic phenotypes in resected lung cancer

scientific article published on 16 April 2020

19q13-ERCC1 gene copy number increase in non--small-cell lung cancer

scientific article published on 15 June 2013

5 protein-based signature for resectable lung squamous cell carcinoma improves the prognostic performance of the TNM staging

scientific article published on 24 November 2018

A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients

scientific article published on 28 January 2013

A Five-Gene and Corresponding Protein Signature for Stage-I Lung Adenocarcinoma Prognosis ⬇️

scientific article published on December 16, 2010

A Functional Spatial Analysis Platform for Discovery of Immunological Interactions Predictive of Low-Grade to High-Grade Transition of Pancreatic Intraductal Papillary Mucinous Neoplasms

scientific article published on 28 June 2018

A Grading system for invasive pulmonary adenocarcinoma: a proposal from the IASLC pathology committee

scientific article published on 17 June 2020

A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal Transition

scientific article published on 29 September 2015

A Phase I/II Study of Neoadjuvant Cisplatin, Docetaxel and Nintedanib for Resectable Non-Small Cell Lung Cancer

scientific article published on 19 March 2020

A Phase II Study of Gefitinib for Aggressive Cutaneous Squamous Cell Carcinoma of the Head and Neck ⬇️

scientific article published on January 18, 2012

A Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesothelioma

scientific article published on 01 July 2020

A Prospective, Multi-institutional, Pathologist-Based Assessment of 4 Immunohistochemistry Assays for PD-L1 Expression in Non-Small Cell Lung Cancer

scientific article published on 09 March 2017

A Semantic Web management model for integrative biomedical informatics

scientific article

A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis.

scientific article published on 30 April 2018

A novel protein-based prognostic signature improves risk stratification to guide clinical management in early-stage lung adenocarcinoma patients

scientific article published on 20 June 2018

A peptide selected by biopanning identifies the integrin alphavbeta6 as a prognostic biomarker for nonsmall cell lung cancer

scientific article

A phase I/II study combining erlotinib and dasatinib for non-small cell lung cancer

scientific article published on 28 August 2014

A proposal for pathologic processing of breast implant capsules in patients with suspected breast implant anaplastic large cell lymphoma

scientific article published on 05 August 2019

A reevaluation of CD22 expression in human lung cancer

scientific article published on January 2014

A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets

scientific article

A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant K-ras

scientific article

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers

scientific article

ATIM-08. IMMUNOMARKERS IN THE DNX-2401 (DELTA-24-RGD) ONCOLYTIC VIRUS PHASE I CLINICAL TRIAL

Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters

scientific article

Aberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas

scientific article published on 16 June 2014

Aberrant methylation of Reprimo in human malignancies

scientific article

Aberrant promoter hypermethylation of multiple genes in gallbladder carcinoma and chronic cholecystitis

scientific article published in September 2004

Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis ⬇️

scientific article published on January 21, 2011

Abstract 1855: SCT methylation is a potential cancer biomarker for lung cancer

Achieving complete remission in CLL patients treated with ibrutinib: clinical significance and predictive factors

scientific article published on 01 February 2020

Activating Enhancer-Binding Protein-2β Nucleolar Localization Predicts Poor Survival After Stage I Non-Small Cell Lung Cancer Resection ⬇️

scientific article published on September 1, 2011

Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer

scientific article

Adding Erlotinib to Chemoradiation Improves Overall Survival but Not Progression-Free Survival in Stage III Non-Small Cell Lung Cancer

scientific article published on June 2015

Agreement on Major Pathological Response in NSCLC Patients Receiving Neoadjuvant Chemotherapy

scientific article published on 04 March 2020

Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling

scientific article

Allelotyping, microsatellite instability, and BRAF mutation analyses in common and atypical melanocytic nevi and primary cutaneous melanomas

scientific article

Altered regulation of HIF-1α in naïve- and drug-resistant EGFR mutant NSCLC: implications for a VEGF-dependent phenotype

scientific article published on 09 December 2020

Amplification of chromosomal segment 4q12 in non-small cell lung cancer

scientific article

An Expression Signature as an Aid to the Histologic Classification of Non-Small Cell Lung Cancer

scientific article published on 28 June 2016

An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2.

scientific article published on 15 April 2015

An Integrated Next-Generation Sequencing System for Analyzing DNA Mutations, Gene Fusions, and RNA Expression in Lung Cancer

article

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance

scientific article published on 22 October 2012

An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis

scientific article published on 13 May 2020

An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.

scientific article

An update on clinicopathological, immunohistochemical, and molecular profiles of colloid carcinoma of the lung

scientific article published on 20 February 2015

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

scientific article published on 14 June 2016

Application of a methylation gene panel by quantitative PCR for lung cancers

scientific article

Aromatase expression predicts survival in women with early-stage non small cell lung cancer

scientific article published on November 2007

Atypical presentation of a colorectal carcinoma

scientific article published in August 2004

Augmented Lipocalin-2 is Associated with COPD and Counteracts Lung Adenocarcinoma Development

scientific article published on 30 July 2020

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

scientific article published on 01 May 2019

Author Correction: Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

scientific article published in Nature Communications

B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density

scientific article published on 26 February 2019

BRAF mutation: a frequent event in benign, atypical, and malignant melanocytic lesions of the skin

scientific article published in October 2003

Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer

scientific article published on 18 December 2018

Biological activity of celecoxib in the bronchial epithelium of current and former smokers

scientific article

Biomarker analyses from a placebo-controlled phase II study evaluating erlotinib±onartuzumab in advanced non-small cell lung cancer: MET expression levels are predictive of patient benefit

scientific article published on 31 March 2014

Biomarker-Integrated Neoadjuvant Dasatinib Trial in Resectable Malignant Pleural Mesothelioma

scientific article published on 4 December 2017

Bronchioalveolar cell carcinoma: radiologic appearance and dilemmas in the assessment of response

scientific article published in September 2004

Bronchioloalveolar carcinoma and lung adenocarcinoma: the clinical importance and research relevance of the 2004 World Health Organization pathologic criteria.

scientific article published on November 2006

Bronchioloalveolar carcinoma: a translational perspective

scientific article published on 01 September 2010

CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade

scientific article published on 16 July 2018

CD73 expression defines immune, molecular, and clinicopathological subgroups of lung adenocarcinoma

scientific article published on 08 January 2021

CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110

scientific article

CLINICAL AND GENOMIC CHARACTERISTICS OF SMALL CELL LUNG CANCER IN NEVER-SMOKERS: RESULTS FROM A RETROSPECTIVE MULTICENTER COHORT STUDY

scientific article published on 25 May 2020

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

scientific article published on 24 May 2017

CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma

scientific article published on 30 November 2012

Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma

scientific article published on 2 December 2015

Centrifuged supernatants from FNA provide a liquid biopsy option for clinical next-generation sequencing of thyroid nodules

scientific article published on 08 January 2019

Challenges in Facing the Lung Cancer Epidemic and Treating Advanced Disease in Latin America

scientific article published on 5 June 2016

Characteristic genetic alterations in lung cancer

scientific article

Characterization and Comparison of GITR Expression in Solid Tumors

scientific article published on 29 July 2019

Characterization of the immune landscape of EGFR-mutant NSCLC identifies CD73/adenosine pathway as a potential therapeutic target

scientific article published on 31 December 2020

Characterizing the cancer genome in lung adenocarcinoma

scientific article

Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling

scientific article published on 19 October 2012

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer.

scientific article published on 11 April 2018

Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

scientific article published in Nature Communications

Clinical Outcomes and Biomarker Profiles of Elderly Pretreated NSCLC Patients from the BATTLE Trial ⬇️

scientific article published on November 1, 2012

Clinical and biomarker outcomes of the phase II vandetanib study from the BATTLE trial

scientific article published on May 2013

Clinicopathologic characteristics of the EGFR gene mutation in non-small cell lung cancer

scientific article published in March 2006

Clinicopathological and immunohistochemical analysis of spindle-cell carcinoid tumour of the lung ⬇️

scientific article published on 01 September 2011

Clonality of combined tumors

scientific article published on 01 April 2002

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

scientific article

Collagen XXIII: a potential biomarker for the detection of primary and recurrent non-small cell lung cancer

scientific article

Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion

scientific article published on 09 September 2020

Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis

scientific article published on 24 January 2012

Combined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations

scientific article

Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers

scientific article published on 30 November 2016

Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16-Related Cancer: A Phase 2 Clinical Trial

article

Comparative analysis of loss of heterozygosity and microsatellite instability in adult and pediatric melanoma.

scientific article

Comparative immunohistochemical analysis of pulmonary and thymic neuroendocrine carcinomas using PAX8 and TTF-1 ⬇️

scientific article published on June 21, 2013

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive Computational Pathological Image Analysis Predicts Lung Cancer Prognosis

scientific article

Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

scientific article published on 15 April 2020

Comprehensive T cell repertoire characterization of non-small cell lung cancer

scientific article published on 30 January 2020

Comprehensive biomarker analysis and final efficacy results of sorafenib in the BATTLE trial

scientific article published on 28 October 2013

Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer

scientific article published on 08 January 2020

Computed tomography RECIST assessment of histopathologic response and prediction of survival in patients with resectable non-small-cell lung cancer after neoadjuvant chemotherapy

scientific article published on February 2013

Concomitant targeting of the mTOR/MAPK pathways: novel therapeutic strategy in subsets of -altered non-small cell lung cancer

ConvPath: A software tool for lung adenocarcinoma digital pathological image analysis aided by a convolutional neural network

scientific article published on 22 November 2019

Copper transporter CTR1 expression and tissue platinum concentration in non-small cell lung cancer

scientific article

Correction: Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation

scientific article published on 01 February 2020

Correction: LCE: an open web portal to explore gene expression and clinical associations in lung cancer

scientific article published on 01 January 2020

Corrigendum to “PIAS1-FAK Interaction Promotes the Survival and Progression of Non–Small Cell Lung Cancer” [Neoplasia 18 (2016) 282-293].

scientific article published on 17 July 2016

Cotargeting Cyclin D1 Starts a New Chapter in Lung Cancer Prevention and Therapy ⬇️

scientific article (publication date: June 2011)

Cross-site concordance evaluation of tumor DNA and RNA sequencing platforms for the CIMAC-CIDC network

scientific article published on 15 December 2020

Current Status and Future Perspectives on Neoadjuvant Therapy in Lung Cancer

scientific article published on 27 September 2018

Current concepts on the molecular pathology of non-small cell lung carcinoma

scientific article

Cyclic AMP response element-binding protein overexpression: a feature associated with negative prognosis in never smokers with non-small cell lung cancer

scientific article

Cystic bronchioloalveolar cell carcinoma

scientific article published in May 2005

Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene

scientific article

DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transition

scientific article

DNA methylation intratumor heterogeneity in localized lung adenocarcinomas

scientific article published on March 2017

Data driven semantic integration of translational lung cancer research at MDAnderson Cancer Center.

scientific article

De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer

scientific article published on 15 June 2018

DeMix: deconvolution for mixed cancer transcriptomes using raw measured data ⬇️

scientific article published on May 27, 2013

Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas.

scientific article published on 26 May 2009

Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors

scientific article published on 09 January 2014

Decrease in tumor content assessed in biopsies is associated with improved treatment outcome response to pembrolizumab in patients with rare tumors

scientific article published on 01 April 2020

Delineation of a Cellular Hierarchy in Lung Cancer Reveals an Oncofetal Antigen Expressed on Tumor-Initiating Cells ⬇️

scientific article (publication date: 15 June 2011)

Density, Distribution, and Composition of Immune Infiltrates Correlate with Survival in Merkel Cell Carcinoma

scientific article published on 10 May 2016

Detection of somatic mutations in cell-free DNA in plasma and correlation with overall survival in patients with solid tumors.

scientific article published on 24 October 2017

Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer

scientific article published on 27 February 2017

Development and Application of Duplex Sequencing Strategy for Cell-Free DNA-Based Longitudinal Monitoring of Stage IV Colorectal Cancer

scientific article published on 08 August 2019

Development and Validation of a Predictive Radiomics Model for Clinical Outcomes in Stage I Non-small Cell Lung Cancer

scientific article published on 15 November 2017

Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a

scientific article published on 27 June 2017

Development of an Immune-Pathology Informed Radiomics Model for Non-Small Cell Lung Cancer.

scientific article published on 31 January 2018

Diagnosis and Molecular Classification of Lung Cancer

scientific article

Diagnosis of lung adenocarcinoma in resected specimens: implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification

scientific article published on 12 September 2012

Diagnosis of lung cancer in small biopsies and cytology: implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification

scientific article published on 12 September 2012

Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures.

scientific article

Differential expression of somatostatin receptors 1–5 in neuroendocrine carcinoma of the lung ⬇️

scientific article published on July 6, 2012

Differential impacts of insulin-like growth factor-binding protein-3 (IGFBP-3) in epithelial IGF-induced lung cancer development.

scientific article

Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1)

article published in the Proceedings of the National Academy of Sciences of the United States of America

Distinct K-ras mutation pattern characterizes signet ring cell colorectal carcinoma ⬇️

scientific article published on September 1, 2003

Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma

scientific article published on 2 February 2016

Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation

scientific article published on 21 November 2019

Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development

scientific article

Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer

scientific article published on 01 September 2019

Dynamic changes during the treatment of pancreatic cancer

scientific article published on 13 February 2018

Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer.

scientific article

EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients

scientific article

ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion

scientific article published on 16 April 2012

ETS2 Mediated Tumor Suppressive Function and MET Oncogene Inhibition in Human Non–Small Cell Lung Cancer ⬇️

scientific article published on 09 May 2013

EZH2 protein expression associates with the early pathogenesis, tumor progression, and prognosis of non-small cell lung carcinoma

scientific article published on 04 October 2013

Early Events in the Molecular Pathogenesis of Lung Cancer

scientific article

Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome

scientific article

Effect of neoadjuvant chemotherapy on the immune microenvironment in non-small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches.

scientific article published on 6 June 2018

Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells

scientific article

Elevated PDGFRB gene copy number gain is prognostic for improved survival outcomes in resected malignant pleural mesothelioma

scientific article

Elevated epithelial insulin-like growth factor expression is a risk factor for lung cancer development

scientific article published on 08 September 2009

Elevated phospho-S6 expression is associated with metastasis in adenocarcinoma of the lung

scientific article published on December 2008

EphA2 in the early pathogenesis and progression of non-small cell lung cancer

scientific article published on 24 November 2009

Epidermal growth factor receptor (EGFR) expression in periocular and extraocular sebaceous carcinoma.

scientific article

Epidermal growth factor receptor abnormalities in lung cancer. Pathogenetic and clinical implications

scientific article

Epidermal growth factor receptor abnormalities in the pathogenesis and progression of lung adenocarcinomas

scientific article

Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors

scientific article published on 22 February 2012

Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma

scientific article published on 5 February 2016

Epithelial-to-mesenchymal transition in the development and progression of adenocarcinoma and squamous cell carcinoma of the lung

scientific article published on 06 March 2009

Erlotinib and the Risk of Oral Cancer: The Erlotinib Prevention of Oral Cancer (EPOC) Randomized Clinical Trial.

scientific article published on 5 November 2015

Erratum: NRF2 regulates serine biosynthesis in non–small cell lung cancer

scientific article published on 01 April 2016

Essential role of aldehyde dehydrogenase 1A3 for the maintenance of non-small cell lung cancer stem cells is associated with the STAT3 pathway

scientific article published on 6 June 2014

Ethnicity affects EGFR and KRAS gene alterations of lung adenocarcinoma

scientific article

Evaluating Circulating Tumor DNA From the Cerebrospinal Fluid of Patients With Melanoma and Leptomeningeal Disease

scientific article published on 01 July 2018

Evolution of genomic and T cell repertoire heterogeneity of malignant pleural mesothelioma under dasatinib treatment

scientific article published on 14 August 2020

Evolving Concepts in Lung Carcinogenesis ⬇️

scientific article published on April 15, 2011

Evolving concepts in the pathology and computed tomography imaging of lung adenocarcinoma and bronchioloalveolar carcinoma

scientific article

Exponential decay nonlinear regression analysis of patient survival curves: preliminary assessment in non-small cell lung cancer

scientific article published on February 2011

Expression of BCL2 alternative proteins and association with outcome in CLL patients treated with venetoclax

scientific article published on 17 December 2020

Expression of Epithelial-Mesenchymal Transition Markers in Treated Pancreatic Ductal Adenocarcinoma

scientific article published on 01 November 2019

Expression of PD-1 and PD-L1 in thymic epithelial neoplasms

scientific article published on 10 March 2017

Expression of insulin-like growth factor I receptor as a biomarker for predicting prognosis in biliary tract cancer patients

scientific article published on 25 February 2015

Expression of interleukin-1 receptor-associated kinase-1 in non-small cell lung carcinoma and preneoplastic lesions

scientific article

Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non-small cell lung cancer

scientific article

Expression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung

scientific article published on 21 February 2012

Expression signatures of metastatic capacity in a genetic mouse model of lung adenocarcinoma

scientific article

Extrahepatic bile duct adenocarcinoma: patients at high-risk for local recurrence treated with surgery and adjuvant chemoradiation have an equivalent overall survival to patients with standard-risk treated with surgery alone

scientific article

Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis

scientific article published on 27 July 2016

Feasibility of image-guided transthoracic core-needle biopsy in the BATTLE lung trial

scientific article published on April 2013

Female Gender Predicts Augmented Immune Infiltration in Lung Adenocarcinoma

scientific article published on 14 June 2020

Fibulin-2 Is a Driver of Malignant Progression in Lung Adenocarcinoma ⬇️

scientific article published on June 10, 2013

Field cancerization in non-small cell lung cancer: implications in disease pathogenesis

scientific article

Fragile histidine triad gene abnormalities in the pathogenesis of gallbladder carcinoma

scientific article published on June 2002

Frequent coamplification and cooperation between C-MYC and PVT1 oncogenes promote malignant pleural mesothelioma

scientific article

Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts ⬇️

scientific article published on October 1, 2011

From Uniplex to Multiplex Molecular Profiling in Advanced Non-Small Cell Lung Carcinoma

scientific article published on September 2015

From clinical specimens to human cancer preclinical models-a journey the NCI-cell line database-25 years later

scientific article published on 05 December 2019

GLI1 Blockade Potentiates the Antitumor Activity of PI3K Antagonists in Lung Squamous Cell Carcinoma

scientific article

Gallbladder cancer: lessons from a rare tumour

scientific article published in September 2004

Gene expression profiling of lichenoid dermatitis immune-related adverse event from immune checkpoint inhibitors reveals increased CD14+ and CD16+ monocytes driving an innate immune response

scientific article published on 11 April 2019

Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition

scientific article

Genetic characterization of medullary thyroid cancer in childhood survivors of the Chernobyl accident

Genetic mutation of p53 and suppression of the miR-17∼92 cluster are synthetic lethal in non-small cell lung cancer due to upregulation of vitamin D Signaling

scientific article

Genetics of preneoplasia: lessons from lung cancer

scientific article published on February 2007

Genome-wide gene expression changes in the normal-appearing airway during the evolution of smoking-associated lung adenocarcinoma.

scientific article

Genomic Landscape Established by Allelic Imbalance in the Cancerization Field of a Normal Appearing Airway

scientific article

Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma

scientific article published on 26 September 2017

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.

scientific article

Genomic assessment distinguishes intrapulmonary metastases from synchronous primary lung cancers

scientific article published on 01 May 2020

Genomic heterogeneity of multiple synchronous lung cancer

scientific article published on 21 October 2016

Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung

Germ-line and somatic presentations of the EGFR T790M mutation in lung cancer

scientific article published in January 2009

Germline Mutation of T790M and Dual/Multiple EGFR Mutations in Patients With Lung Adenocarcinoma

scientific article

Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion

scientific article

HER Receptor Family: Novel Candidate for Targeted Therapy for Gallbladder and Extrahepatic Bile Duct Cancer

scientific article

HER family receptor abnormalities in lung cancer brain metastases and corresponding primary tumors

scientific article

HER family receptor and ligand status in thymic carcinoma ⬇️

scientific article published on June 20, 2012

HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy

scientific article

HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress

scientific article published on 05 September 2018

High OX-40 expression in the tumor immune infiltrate is a favorable prognostic factor of overall survival in non-small cell lung cancer

scientific article published on 16 December 2019

High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor

scientific article published in December 2005

High expression of folate receptor alpha in lung cancer correlates with adenocarcinoma histology and EGFR [corrected] mutation

scientific article

High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras

scientific journal article

Histologic features of low- and intermediate-grade neuroendocrine carcinoma (typical and atypical carcinoid tumors) of the lung

scientific article published on 11 May 2010

Histologic patterns and molecular characteristics of lung adenocarcinoma associated with clinical outcome ⬇️

scientific article published on October 21, 2011

Histopathologic response criteria predict survival of patients with resected lung cancer after neoadjuvant chemotherapy

scientific article

Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations

scientific article published on 28 February 2013

Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells.

scientific article

Hypertrophic lichenoid dermatitis immune-related adverse event during combined immune checkpoint and exportin inhibitor therapy: A diagnostic pitfall for superficially invasive squamous cell carcinoma

scientific article published on 12 May 2020

IASLC Multidisciplinary Recommendations for Pathologic Assessment of Lung Cancer Resection Specimens After Neoadjuvant Therapy

scientific article published on 28 January 2020

IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer

scientific article published on April 2016

Identification and validation of differences in protein levels in normal, premalignant, and malignant lung cells and tissues using high-throughput Western Array and immunohistochemistry

scientific article published on December 2006

Identification of a subset of human non-small cell lung cancer patients with high PI3Kβ and low PTEN expression, more prevalent in squamous cell carcinoma

scientific article published on 27 November 2013

Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system

scientific article

Identification of novel cellular targets in biliary tract cancers using global gene expression technology

scientific article published on July 2003

Image Analysis-based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non-small Cell Lung Carcinoma Patients

scientific article published on June 2016

Image-Guided Biopsy in the Era of Personalized Cancer Care: Proceedings from the Society of Interventional Radiology Research Consensus Panel

scientific article

Immune regulatory markers of lepidic-pattern adenocarcinomas presenting as ground glass opacities

scientific article published on 01 March 2020

Immunohistochemical Overexpression of Platelet-Derived Growth Factor Receptor–Beta (PDGFR-β) is Associated With PDGFRB Gene Copy Number Gain in Sarcomatoid Non–Small-Cell Lung Cancer ⬇️

scientific article published on May 17, 2011

Immunohistochemical and Image Analysis-Based Study Shows That Several Immune Checkpoints are Co-expressed in Non-Small Cell Lung Carcinoma Tumors.

scientific article published on 8 March 2018

Immunohistochemical expression of basic fibroblast growth factor and fibroblast growth factor receptors 1 and 2 in the pathogenesis of lung cancer

scientific article published on October 2008

Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation

scientific article

Immunotherapy response evaluation with magnetic resonance elastography (MRE) in advanced HCC

scientific article published on 28 November 2019

Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples

scientific article

Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin

scientific article published on December 2007

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

scientific article published on 05 April 2018

Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy

scientific article

Induction Cisplatin Docetaxel Followed by Surgery and Erlotinib in Non-Small Cell Lung Cancer

scientific article published on 4 December 2017

Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion

scientific article published on July 2007

Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras

scientific article

Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network

scientific article published on 18 December 2018

Inhibitor of differentiation-1 as a novel prognostic factor in NSCLC patients with adenocarcinoma histology and its potential contribution to therapy resistance

scientific article published on 3 May 2011

Integrating whole transcriptome sequence data and public databases for analysis of somatic mutations in tumors.

scientific article published on 19 September 2011

Integration of Molecular Profiling into the Lung Cancer Clinic

scientific article published on 25 August 2009

Integrative proteomic and transcriptomic analysis provides evidence for TrkB (NTRK2) as a therapeutic target in combination with tyrosine kinase inhibitors for non-small cell lung cancer

scientific article published on 30 January 2018

Interleukin-11 Receptor Is a Candidate Target for Ligand-Directed Therapy in Lung Cancer: Analysis of Clinical Samples and BMTP-11 Preclinical Activity

scientific article published on 15 June 2016

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma

scientific article

Interobserver Variation Among Pathologists And Refinement Of Criteria In Distinguishing Separate Primary Tumours From Intrapulmonary Metastases In Lung.

scientific article

Interplay between Estrogen and Stat3/NF-κB Driven Immunomodulation in Lung Cancer

scientific article published on 30 June 2020

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

scientific article published in October 2014

Intratumoral epiregulin is a marker of advanced disease in non-small cell lung cancer patients and confers invasive properties on EGFR-mutant cells

scientific article

JAK1/STAT3 activation through a proinflammatory cytokine pathway leads to resistance to molecularly targeted therapy in non-small cell lung cancer

scientific article published on 20 July 2017

KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib

scientific article published on 17 November 2015

KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer

scientific article published on May 2007

Kinase-Impaired BRAF Mutations in Lung Cancer Confer Sensitivity to Dasatinib ⬇️

scientific article published on May 30, 2012

LAPTM4B is associated with poor prognosis in NSCLC and promotes the NRF2-mediated stress response pathway in lung cancer cells

scientific article published on 7 September 2015

LCE: an open web portal to explore gene expression and clinical associations in lung cancer

article

LKB1/STK11 Expression in Lung Adenocarcinoma and Associations with Patterns of Recurrence

scientific article published on 19 May 2020

LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer

scientific article published on 03 July 2018

Liquid Biopsy for Advanced Non-Small Cell Lung Cancer (NSCLC): A Statement Paper from the IASLC

article

Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment.

scientific article published on 8 June 2015

Loss and reduction of FUS1 protein expression is a frequent phenomenon in the pathogenesis of lung cancer

scientific article

Lung Cancer Biomarkers

scientific article published on February 2017

Lung cancer preneoplasia

scientific article published on January 2006

Lung cancer stem cell: fancy conceptual model of tumor biology or cornerstone of a forthcoming therapeutic breakthrough?

scientific article published on January 2014

Lymphovascular Invasion Is Associated With Mutational Burden and PD-L1 in Resected Lung Cancer

scientific article published on 21 September 2019

Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma

scientific article

Major pathologic response and RAD51 predict survival in lung cancer patients receiving neoadjuvant chemotherapy.

scientific article

Malignant pleural mesothelioma

scientific article published on 02 March 2009

Map2k4 Functions as a Tumor Suppressor in Lung Adenocarcinoma and Inhibits Tumor Cell Invasion by Decreasing Peroxisome Proliferator-Activated Receptor γ2 Expression ⬇️

scientific article published on September 6, 2011

Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects.

scientific article published on 24 October 2009

Mesonephric-like Carcinoma of the Endometrium: A Subset of Endometrial Carcinoma With an Aggressive Behavior

scientific article published on 01 April 2020

Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer

scientific article published on 28 May 2013

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

scientific article

Methodological and practical challenges for personalized cancer therapies ⬇️

scientific article published on March 1, 2011

Methylation of the candidate biomarker TCF21 is very frequent across a spectrum of early-stage nonsmall cell lung cancers

scientific article

MicroRNA 96 Is a Post-Transcriptional Suppressor of Anaplastic Lymphoma Kinase Expression ⬇️

scientific article published on March 10, 2012

Microsatellite analysis of synchronous and metachronous tumors: a tool for double primary tumor and metastasis assessment

scientific article published on September 2003

Mig-6 deficiency cooperates with oncogenic Kras to promote mouse lung tumorigenesis.

scientific article published on 5 August 2017

Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis

scientific journal article

Mitochondrial DNA mutation at the D310 (displacement loop) mononucleotide sequence in the pathogenesis of gallbladder carcinoma

scientific article published on February 2004

Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway

scientific article published on 11 December 2006

Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations

scientific article published on 16 December 2015

Molecular Testing for Treatment of Metastatic Non-Small Cell Lung Cancer: How to Implement Evidence-Based Recommendations

scientific article

Molecular aspects of thymic carcinoma

scientific article published on 24 August 2012

Molecular biology, genomics, and proteomics in bronchioloalveolar carcinoma

scientific article published on November 2006

Molecular differences across invasive lung adenocarcinoma morphological subgroups ⬇️

scientific article published on 01 August 2020

Molecular pathology of thymic epithelial neoplasms

scientific article published on June 2008

Mortality in the randomized, controlled lung intergroup trial of isotretinoin

scientific article

Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience

scientific article published on May 2015

Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

scientific article published on 05 July 2019

Multifactorial Deep Learning Reveals Pan-Cancer Genomic Tumor Clusters with Distinct Immunogenomic Landscape and Response to Immunotherapy

scientific article published on 07 January 2020

Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity

scientific article published on 04 November 2020

Multiplex Immunofluorescence Assays

scientific article published on 01 January 2020

Multiregion gene expression profiling reveals heterogeneity in molecular subtypes and immunotherapy response signatures in lung cancer

scientific article

Mutations and PD-1 Inhibitor Resistance in -Mutant Lung Adenocarcinoma

scientific article published on 17 May 2018

NRF2 regulates serine biosynthesis in non-small cell lung cancer

scientific article

Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa

scientific article published on 08 July 2020

Neoadjuvant Chemotherapy Increases Cytotoxic T cell, Tissue Resident Memory T cell and B Cell Infiltration in Resectable Non-Small Cell Lung Cancer

scientific article published on 20 October 2020

Neoadjuvant chemotherapy and nivolumab in resectable non-small-cell lung cancer (NADIM): an open-label, multicentre, single-arm, phase 2 trial

scientific article published on 24 September 2020

Network for biomarker immunoprofiling for cancer immunotherapy: Cancer Immune Monitoring and Analysis Centers and Cancer Immunologic Data Commons (CIMAC-CIDC)

scientific article published on 08 January 2021

NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM.

scientific article published on 3 April 2013

Neutrophil expansion defines an immunoinhibitory peripheral and intratumoral inflammatory milieu in resected non-small cell lung cancer: a descriptive analysis of a prospectively immunoprofiled cohort

scientific article published on 01 April 2020

New Approaches to SCLC Therapy: From the Laboratory to the Clinic

scientific article published on 01 February 2020

New Strategies in Squamous Cell Carcinoma of the Lung: Identification of Tumor Drivers to Personalize Therapy ⬇️

scientific article published on March 29, 2012

Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer

scientific article

Non-invasive genotyping of metastatic colorectal cancer using circulating cell free DNA

scientific article published on 12 June 2019

Novel enriched pathways in superficial malignant peripheral nerve sheath tumours and spindle/desmoplastic melanomas

scientific article

Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features

scientific article

Nuclear Receptor Expression Defines a Set of Prognostic Biomarkers for Lung Cancer ⬇️

scientific article (publication date: 14 December 2010)

Nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung cancer and preneoplastic lesions

scientific article published on 01 December 2006

Nuclear morphometry as a biomarker for bronchial intraepithelial neoplasia: correlation with genetic damage and cancer development

scientific article

ORAL01.01: A Prospective, Multi-Institutional Assessment of Four Assays for PD-L1 Expression in NSCLC by Immunohistochemistry: Topic: Pathology

scientific article

Oncocytic neuroendocrine tumors of the lung: histopathologic spectrum and immunohistochemical analysis of 15 cases ⬇️

scientific article published on February 16, 2011

Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells

scientific article

Oncogenic enhancer of zeste homolog 2 is an actionable target in patients with non-small cell lung cancer

scientific article published on 27 August 2019

Optimizing the DNA yield for molecular analysis from cytologic preparations

scientific article published on 2 December 2015

Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFβRIII-p38MAPK-pS249/T252RB pathway.

scientific article published on 7 March 2018

PD-L1 Expression, Tumor Mutational Burden, and Cancer Gene Mutations Are Stronger Predictors of Benefit from Immune Checkpoint Blockade than HLA Class I Genotype in Non-Small Cell Lung Cancer

scientific article published on 16 February 2019

PD-L1 Immunohistochemistry Comparability Study in Real-Life Clinical Samples: Results of Blueprint Phase 2 Project

article by Ming-Sound Tsao et al published September 2018 in Journal of Thoracic Oncology

PD-L1 Testing for Lung Cancer in 2019: Perspective From the IASLC Pathology Committee

scientific article published on 20 December 2019

PI3-kinase pathway biomarkers in oral cancer and tumor immune cells

scientific article published on 16 December 2018

PI4KIIIβ is a therapeutic target in chromosome 1q-amplified lung adenocarcinoma

scientific article published on 01 January 2020

PIAS1-FAK Interaction Promotes the Survival and Progression of Non-Small Cell Lung Cancer

scientific article

PIK3CA mutations and copy number gains in human lung cancers

scientific article

PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis

scientific article published on 7 November 2016

Pathologic Assessment of Lung Squamous Cell Carcinoma After Neoadjuvant Immunotherapy

scientific article published on 01 January 2021

Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial

scientific article published on 4 October 2017

Perfecting the fine-needle aspirate cell block

scientific article published in March 2013

Personalizing lung cancer prevention through a reverse migration strategy

scientific article published on January 2013

Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma

scientific article published on 12 February 2018

Phase I Trial of Cediranib in combination with cisplatin and pemetrexed in chemo naive patients with unresectable malignant pleural mesothelioma (SWOG S0905).

scientific article

Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans ⬇️

scientific article published on April 25, 2012

Phase I study of azacitidine and oxaliplatin in patients with advanced cancers that have relapsed or are refractory to any platinum therapy

scientific article

Phase I trial of cisplatin, pemetrexed, and imatinib mesylate in chemonaive patients with unresectable malignant pleural mesothelioma

scientific article published on 27 December 2013

Phase II Study of Dasatinib in Patients With Advanced Non–Small-Cell Lung Cancer ⬇️

scientific article published on September 20, 2010

Phase II Trial of Cediranib in Combination With Cisplatin and Pemetrexed in Chemotherapy-Naïve Patients With Unresectable Malignant Pleural Mesothelioma (SWOG S0905)

scientific article published on 06 August 2019

Phase II Trials of Imatinib Mesylate and Docetaxel in Patients with Metastatic Non-small Cell Lung Cancer and Head and Neck Squamous Cell Carcinoma ⬇️

scientific article published on December 1, 2011

Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions

scientific article

Phosphatidylinositol 3-kinase mediates bronchioalveolar stem cell expansion in mouse models of oncogenic K-ras-induced lung cancer

scientific article

Plasma-Derived Extracellular Vesicles Convey Protein Signatures that Reflect Pathophysiology in Lung and Pancreatic Adenocarcinomas

scientific article published on 02 May 2020

Plasma-derived extracellular vesicle proteins as a source of biomarkers for lung adenocarcinoma

scientific article published on 8 September 2017

Pleural Fluid Cytokine Levels at Baseline and Over Time are Associated With Time to IPC Removal: An Exploratory Study

scientific article published on 01 January 2020

Pleuropulmonary Meningothelial Proliferations: Evidence for a Common Histogenesis

scientific article

Polo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations.

scientific article published on 30 June 2016

Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers

scientific article published on 6 February 2018

Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers

scientific article (publication date: April 2007)

Prediction of survival in resected non-small cell lung cancer using a protein expression-based risk model: implications for personalized chemoprevention and therapy

scientific article

Predictive biomarkers of response to PD-1/PD-L1 immune checkpoint inhibitors in non-small cell lung cancer

scientific article

Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer

scientific article

Primary Mediastinal Yolk Sac Tumors: An Immunohistochemical Analysis of 14 Cases

scientific article published on 01 February 2019

Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers

scientific article

Primary oncocytic adenocarcinomas of the lung: a clinicopathologic, immunohistochemical, and molecular biologic analysis of 16 cases

scientific article published on 01 January 2010

Procedural Requirements and Recommendations for Multiplex Immunofluorescence Tyramide Signal Amplification Assays to Support Translational Oncology Studies

scientific article published on 21 January 2020

Prognostic Factors of Hepatosplenic T-cell Lymphoma: Clinicopathologic Study of 28 Cases

scientific article

Prognostic Significance of Tumor-Infiltrating Lymphocytes in Patients With Pancreatic Ductal Adenocarcinoma Treated With Neoadjuvant Chemotherapy

scientific article

Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer ⬇️

scientific article published on September 22, 2011

Prognostic implications of tumoral expression of insulin like growth factors 1 and 2 in patients with non-small-cell lung cancer

scientific article

Prognostic significance of RNA-dependent protein kinase on non-small cell lung cancer patients

scientific article

Prognostic significance of combinations of RNA-dependent protein kinase and EphA2 biomarkers for NSCLC.

scientific article published on March 2013

Programmed Death Cell Ligand 1 (PD-L1) Is Associated With Survival in Stage I Non-Small Cell Lung Cancer

scientific article published on 26 May 2017

Programmed Death Ligand 1 Heterogeneity and its Impact on Benefit from Immune Checkpoint Inhibitors in Non-Small-Cell Lung Cancer

scientific article published on 07 May 2020

Programmed Death-Ligand 1 Immunohistochemistry in Lung Cancer: In what state is this art?

scientific article published on July 2015

Programmed cell death ligand 1 and tumor-infiltrating lymphocyte status in patients with renal cell carcinoma and sarcomatoid dedifferentiation

scientific article

Progression of Gene Hypermethylation in Gallstone Disease Leading to Gallbladder Cancer ⬇️

scientific article published on October 1, 2003

Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model

scientific article published on 16 October 2008

Protein expression of TTF1 and cMYC define distinct molecular subgroups of small cell lung cancer with unique vulnerabilities to aurora kinase inhibition, DLL3 targeting, and other targeted therapies

scientific article published in September 2017

Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.

scientific article published on 6 September 2012

Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence

scientific article

Proteomics-based identification of proteins secreted in apical surface fluid of squamous metaplastic human tracheobronchial epithelial cells cultured by three-dimensional organotypic air-liquid interface method

scientific article

Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer

scientific article published on February 2008

Pulmonary adenocarcinoma: A renewed entity in 2011 ⬇️

scientific article published on January 1, 2012

RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non-small Cell Lung Cancer

scientific article published on 13 October 2017

RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas

scientific article published on 28 January 2013

RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner

scientific article published on 12 November 2013

RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer

scientific article published on May 2015

RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells

scientific article

RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

scientific article published on 26 December 2019

Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer

scientific article published on 31 January 2014

Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer.

scientific article published on 15 June 2018

Rare variants in known susceptibility loci and their contribution to risk of lung cancer

journal article published in 2018

Rational "Error Elimination" Approach to Evaluating Molecular Barcoded Next-Generation Sequencing Data Identifies Low-Frequency Mutations in Hematologic Malignancies

scientific article published on 20 February 2019

Reanalysis of the NCCN PD-L1 companion diagnostic assay study for lung cancer in the context of PD-L1 expression findings in triple-negative breast cancer.

scientific article

Receptor of activated protein C promotes metastasis and correlates with clinical outcome in lung adenocarcinoma

scientific article

Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer

scientific article

Reduced IL-6 levels and tumor-associated phospho-STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo-inositol

scientific article published on 14 November 2017

Reply to Oegema et al.: CFI-400945 and Polo-like kinase 4 inhibition

article published in the Proceedings of the National Academy of Sciences of the United States of America

Reproducibility of histopathological diagnosis in poorly differentiated NSCLC: an international multiobserver study

scientific article published in September 2014

Reproducibility of histopathological subtypes and invasion in pulmonary adenocarcinoma. An international interobserver study ⬇️

scientific article

Requirement for MUC5AC in KRAS-dependent lung carcinogenesis

Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer

scientific article

Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents ⬇️

scientific article published on December 18, 2012

Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients

scientific article

Round Robin Evaluation of MET Protein Expression in Lung Adenocarcinomas Improves Interobserver Concordance

scientific article published on 22 November 2019

SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines

scientific article published on January 2007

STAT5A-Mediated SOCS2 Expression Regulates Jak2 and STAT3 Activity Following c-Src Inhibition in Head and Neck Squamous Carcinoma ⬇️

scientific article published on November 16, 2011

STING Pathway Expression Identifies NSCLC With an Immune-Responsive Phenotype

scientific article published on 15 February 2020

STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.

scientific article published on February 2016

Salvaging the supernatant: next generation cytopathology for solid tumor mutation profiling

scientific article published on 20 February 2018

Sarcomatoid Mesothelioma: A CDKN2A molecular analysis of 53 cases with immunohistochemical correlation with BAP1

scientific article published on 02 November 2020

Sarcomatoid renal cell carcinoma has a distinct molecular pathogenesis, driver mutation profile and transcriptional landscape

scientific article published on 14 July 2017

Serum signature of hypoxia-regulated factors is associated with progression after induction therapy in head and neck squamous cell cancer

scientific article

Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung

scientific article

Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer

scientific article published in Nature Communications

Smoking molecular damage in bronchial epithelium

scientific article

Smoking-related genomic signatures in non-small cell lung cancer

scientific article published on 05 September 2008

Somatic mutations affect key pathways in lung adenocarcinoma

scientific article

Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.

scientific article published on March 2005

Sox10‐positive sustentacular cells in neuroendocrine carcinoma of the lung ⬇️

scientific article published on January 1, 2011

Spatial interaction of tumor cells and regulatory T cells correlates with survival in non-small cell lung cancer.

scientific article published on 3 February 2018

Spindle cell and pleomorphic ("sarcomatoid") carcinomas of the lung: an immunohistochemical analysis of 86 cases

scientific article published on 25 August 2016

Squamous Cell Carcinoma - Similarities and Differences among Anatomical Sites ⬇️

scientific article published on January 1, 2011

Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation

scientific article

Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers

scientific article published in November 2017

Study of Preanalytic and Analytic Variables for Clinical Next-Generation Sequencing of Circulating Cell-Free Nucleic Acid

scientific article published on 12 May 2017

Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5.

scientific article

T CELL REPERTOIRE IN COMBINATION WITH T CELL DENSITY PREDICTS CLINICAL OUTCOMES IN PATIENTS WITH MERKEL CELL CARCINOMA

scientific article published on 15 April 2020

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

scientific article

TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence.

scientific article published on 21 July 2017

TMPRSS4: A Novel Tumor Prognostic Indicator for the Stratification of Stage IA Tumors and a Liquid Biopsy Biomarker for NSCLC Patients

scientific article published on 03 December 2019

TP53 abnormalities are frequent and early events in the sequential pathogenesis of gallbladder carcinoma

scientific article published on July 2005

Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer

scientific article published on 18 February 2019

Targeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer

scientific article published on 4 June 2015

Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors.

scientific article

The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification

scientific article published in September 2015

The BATTLE to Personalize Lung Cancer Prevention through Reverse Migration ⬇️

scientific article published on July 1, 2011

The BATTLE trial: personalizing therapy for lung cancer

scientific article

The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer

scientific article published on August 2016

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer

scientific article

The ISG15-specific protease USP18 regulates stability of PTEN.

scientific article published on 12 December 2016

The Impact of Smoking and TP53 mutations in lung adenocarcinoma patients with targetable mutations - the Lung Cancer Mutation Consortium (LCMC2).

scientific article published on 7 December 2017

The International Association for the Study of Lung Cancer (IASLC) Global Survey on Molecular Testing in Lung Cancer

scientific article published on 14 May 2020

The International Association for the Study of Lung Cancer Consensus Statement on Optimizing Management of EGFR Mutation-Positive Non-Small Cell Lung Cancer: Status in 2016.

scientific article published on 20 May 2016

The Prognostic and Therapeutic Role of Genomic Subtyping by Sequencing Tumor or Cell-Free DNA in Pulmonary Large-Cell Neuroendocrine Carcinoma

scientific article published on 06 November 2019

The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors ⬇️

scientific article published on July 31, 2013

The Role of PKR/eIF2α Signaling Pathway in Prognosis of Non-Small Cell Lung Cancer ⬇️

scientific article published on November 10, 2011

The Society for Immunotherapy in Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation

scientific article published on 01 May 2020

The V599E BRAF mutation is uncommon in biliary tract cancers

scientific article

The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network

scientific article published on 11 January 2018

The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network.

scientific article published on 2 July 2018

The evolving genomic classification of lung cancer

scientific article

The impact of sex and smoking status on the mutational spectrum of epidermal growth factor receptor gene in non small cell lung cancer

scientific article published in October 2007

The multidisciplinary approach to thymoma: combining molecular and clinical approaches

scientific article published on October 2010

The oncogenic RNA-binding protein SRSF1 regulates LIG1 in non-small cell lung cancer

scientific article published on 04 September 2018

The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells

scientific article published on 26 September 2016

Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model

scientific article

Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells

scientific article published on 25 September 2019

Three-Dimensional mRNA Measurements Reveal Minimal Regional Heterogeneity in Esophageal Squamous Cell Carcinoma ⬇️

scientific article published on December 3, 2012

Thy-1+ Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis

scientific article published on 25 July 2017

Thymic neuroendocrine tumors (paraganglioma and carcinoid tumors): a comparative immunohistochemical study of 46 cases

scientific article published on 6 September 2014

Tissue Platinum Concentration and Tumor Response in Non–Small-Cell Lung Cancer ⬇️

scientific article published on August 13, 2012

Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration

Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer

scientific article published on 22 February 2014

Transition from a Standard to a Hybrid On-Site and Remote Anatomic Pathology Training Model During the COVID-19 Pandemic

scientific article published on 16 September 2020

Tumor Mutation Burden: Promises and Challenges A Perspective from the IASLC Pathology Committee

scientific article published on 06 June 2020

Tumor cellular proliferation is associated with enhanced immune checkpoint expression in stage I non-small cell lung cancer

scientific article published on 17 May 2019

Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy

scientific article published on 29 July 2019

Uncommon Epidermal Growth Factor Receptor mutations in non-small cell lung cancer and their mechanisms of EGFR tyrosine kinase inhibitors sensitivity and resistance ⬇️

scientific article published on February 26, 2013

Update on EGFR Mutational Testing and the Potential of Noninvasive Liquid Biopsy in Non-Small-cell Lung Cancer

scientific article published on 12 August 2017

Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs

scientific article

Using the mitosis-specific marker anti-phosphohistone H3 to assess mitosis in pulmonary neuroendocrine carcinomas

scientific article published on 01 August 2011

VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy

scientific article

VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

scientific article

Validation of SCT Methylation as a Hallmark Biomarker for Lung Cancers

scientific article published on 24 December 2015

Validation of a molecular and pathological model for five-year mortality risk in patients with early stage lung adenocarcinoma

scientific article

Validation of a proliferation-based expression signature as prognostic marker in early stage lung adenocarcinoma

scientific article published on 18 September 2013

Validation of multiplex immunofluorescence panels using multispectral microscopy for immune-profiling of formalin-fixed and paraffin-embedded human tumor tissues

scientific article published on 17 October 2017

Validation of the 12-gene predictive signature for Adjuvant Chemotherapy Response in Lung Cancer

article

Vandetanib and indwelling pleural catheter for non-small-cell lung cancer with recurrent malignant pleural effusion

scientific article

Versatile ion S5XL sequencer for targeted next generation sequencing of solid tumors in a clinical laboratory

scientific article

XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.

scientific article published on 28 September 2016

YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib

scientific article published on 01 October 2019

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer

scientific article published on 08 August 2016

ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism

scientific article

ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism

scientific article published on 01 March 2019

eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer

scientific article published on 20 April 2020

g-Protein Coupled Receptor Family C, Group 5, Member A ( gprc5a ) Expression Is Decreased in the Adjacent Field and Normal Bronchial Epithelia of Patients with Chronic Obstructive Pulmonary Disease and Non–Small-Cell Lung Cancer ⬇️

scientific article published on December 1, 2012

miR-337-3p and Its Targets STAT3 and RAP1A Modulate Taxane Sensitivity in Non-Small Cell Lung Cancers ⬇️

scientific article published on June 18, 2012

miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1.

scientific article published on 11 August 2009

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