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List of works by James T B Crawley

ADAMTS13 substrate recognition of von Willebrand factor A2 domain

scientific article

Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain

scientific article

Activated protein C cofactor function of protein S: a novel role for a γ-carboxyglutamic acid residue

scientific article published on 20 April 2011

Activated αIIbβ3 on platelets mediates flow-dependent NETosis via SLC44A2

scientific article published on 21 April 2020

Blocking VWF platelet binding to treat TTP.

scientific article

Cardiovascular string theory ⬇️

scientific article published on 01 March 2012

Circulating ADAMTS-13-von Willebrand factor complexes: an enzyme on demand

scientific article published on 18 September 2009

Conformational activation of ADAMTS13.

scientific article

Crystal structure and substrate-induced activation of ADAMTS13

scientific article published on 22 August 2019

Cytoprotective effect of activated protein C: specificity of PAR-1 signaling

scientific article published on 21 March 2008

Defective fibrin deposition and thrombus stability in Bambi-/- mice are mediated by elevated anticoagulant function

scientific article published on 26 August 2019

Detection of anti-platelet antibodies in immune thrombocytopenia by flow cytometry

scientific article published on 13 March 2018

Differential expression of Toll-like receptors in follicular lymphoma, diffuse large B-cell lymphoma and peripheral T-cell lymphoma.

scientific article published on 25 August 2010

Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality.

scientific article

Essential role of the disintegrin-like domain in ADAMTS13 function.

scientific article published on 20 February 2009

Evidence that high von Willebrand factor and low ADAMTS-13 levels independently increase the risk of a non-fatal heart attack

scientific article published on 11 January 2008

Factor V has an anticoagulant cofactor activity that targets the early phase of coagulation.

scientific article published on 18 April 2017

High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women

scientific article published on 22 November 2011

Identification of functionally important residues in TFPI Kunitz domain 3 required for the enhancement of its activity by protein S

scientific article published on 16 October 2012

Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13).

scientific article

Pathogenicity of Anti-ADAMTS13 Autoantibodies in Acquired Thrombotic Thrombocytopenic Purpura.

scientific article

Plasma ADAMTS-13 levels and the risk of myocardial infarction: an individual patient data meta-analysis.

scientific article

Protective effects of non-anticoagulant activated protein C variant (D36A/L38D/A39V) in a murine model of ischaemic stroke.

scientific article published on April 2015

Proteolytic inactivation of ADAMTS13 by thrombin and plasmin.

scientific article published on 23 September 2004

Proteomic discovery of substrates of the cardiovascular protease ADAMTS7

scientific article published on 29 March 2019

Reduced body weight and increased postimplantation fetal death in tyrosylprotein sulfotransferase-1-deficient mice.

scientific article published on 18 April 2002

Role of a 5'-enhancer in the transcriptional regulation of the human endothelial cell protein C receptor gene

scientific article published on 20 April 2006

SLC44A2 - A novel therapeutic target for venous thrombosis?

scientific article published on 01 July 2020

TFPI cofactor function of protein S: essential role of the protein S SHBG-like domain

scientific article

The ADAMTS13 metalloprotease domain: roles of subsites in enzyme activity and specificity.

scientific article published on 20 July 2010

The haemostatic role of tissue factor pathway inhibitor.

scientific article published on 19 October 2007

The importance of vicinal cysteines, C1669 and C1670, for von Willebrand factor A2 domain function

scientific article

The role of the ADAMTS13 cysteine-rich domain in VWF binding and proteolysis.

scientific article

The roles of factor Va and protein S in formation of the activated protein C/protein S/factor Va inactivation complex

scientific article published on 09 August 2019

Thrombomodulin analogues for the treatment of ischemic stroke

scientific article published on 01 June 2011

Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor.

scientific article published on 29 June 2011

Vessel wall BAMBI contributes to hemostasis and thrombus stability.

scientific article

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