List of works by Joanna S. Fowler

"Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect

scientific article published in June 2002

2-deoxy-2-[18F]fluoro-D-glucose and alternative radiotracers for positron emission tomography imaging using the human brain as a model

scientific article published on April 2004

6-[18F]Fluoro-A-85380, a new PET tracer for the nicotinic acetylcholine receptor: studies in the human brain and in vivo demonstration of specific binding in white matter.

scientific article published in September 2004

A Conversation Between Joanna Fowler and Johannes Czernin

scientific article published on 01 September 2019

A feedback regulatory loop between G3P and lipid transfer proteins DIR1 and AZI1 mediates azelaic-acid-induced systemic immunity

scientific article published on 18 April 2013

A mild, rapid synthesis of freebase [11C]nicotine from [11C]methyl triflate

scientific article published on 29 August 2016

A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator

scientific article

A simple, rapid method for the preparation of [11C]formaldehyde

scientific article published on January 2008

Activation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: relevance to addiction.

scientific article

Acute alcohol intoxication decreases glucose metabolism but increases acetate uptake in the human brain

scientific article

Addiction circuitry in the human brain

scientific article

Addiction: beyond dopamine reward circuitry

scientific article published on 14 March 2011

Addiction: decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain's control circuit

scientific article

Alcohol decreases baseline brain glucose metabolism more in heavy drinkers than controls but has no effect on stimulation-induced metabolic increases

scientific article

Alcohol intoxication induces greater reductions in brain metabolism in male than in female subjects

scientific article

An efficient and practical synthesis of [2-(11)C]indole via superfast nucleophilic [(11)C]cyanation and RANEY® Nickel catalyzed reductive cyclization.

scientific article published in December 2015

Anger and depression in cocaine addiction: association with the orbitofrontal cortex

scientific article published in January 2005

Aromatase imaging with [N-methyl-11C]vorozole PET in healthy men and women.

scientific article published on 19 February 2015

Association between dopamine D4 receptor polymorphism and age related changes in brain glucose metabolism

scientific article

Association of body mass and brain activation during gastric distention: implications for obesity

scientific article

BMI modulates calorie-dependent dopamine changes in accumbens from glucose intake

scientific article

Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [¹¹C]GSK189254 in anesthetized baboon

scientific article

Brain DA D2 receptors predict reinforcing effects of stimulants in humans: replication study

scientific article

Brain dopamine is associated with eating behaviors in humans

scientific article

Brain dopamine transporter levels in treatment and drug naïve adults with ADHD.

scientific article published on 27 November 2006

Brain kinetics of methylphenidate (Ritalin) enantiomers after oral administration

scientific article

Brain monoamine oxidase A activity predicts trait aggression

scientific article published on May 2008

CD15 Expression Does Not Identify a Phenotypically or Genetically Distinct Glioblastoma Population

scientific article

Cardiovascular effects of methylphenidate in humans are associated with increases of dopamine in brain and of epinephrine in plasma

scientific article published on 13 February 2003

Characterisation of [¹¹C]PR04.MZ in Papio anubis baboon: a selective high-affinity radioligand for quantitative imaging of the dopamine transporter.

scientific article published on 25 October 2011

Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction.

scientific article published in June 2006

Cocaine increases the intracellular calcium concentration in brain independently of its cerebrovascular effects.

scientific article published in November 2006

Cocaine is pharmacologically active in the nonhuman primate fetal brain

scientific article

Cognitive control of drug craving inhibits brain reward regions in cocaine abusers.

scientific article

Common human 5' dopamine transporter (SLC6A3) haplotypes yield varying expression levels in vivo

scientific article

Comparison of Brain Glucose Metabolism and Monoamine Oxidase B (MAO B) in Traumatic Brain Injury ⬇️

scientific article published on March 1, 1999

Comparison of monoamine oxidase a in peripheral organs in nonsmokers and smokers.

scientific article

Comparison of the binding of the irreversible monoamine oxidase tracers, [(11)C]clorgyline and [(11)C]l-deprenyl in brain and peripheral organs in humans

scientific article published in April 2004

Comparison of the pharmacokinetics of different analogs of 11C-labeled TZTP for imaging muscarinic M2 receptors with PET.

scientific article

DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking

scientific article

Decreased brain dopamine transporters are related to cognitive deficits in HIV patients with or without cocaine abuse

scientific article published on 20 May 2008

Decreased brain dopaminergic transporters in HIV-associated dementia patients

scientific article

Decreased dopamine brain reactivity in marijuana abusers is associated with negative emotionality and addiction severity

scientific article

Depressed Dopamine Activity in Caudate and Preliminary Evidence of Limbic Involvement in Adults With Attention-Deficit/Hyperactivity Disorder

article

Distribution and pharmacokinetics of methamphetamine in the human body: clinical implications

scientific article

Dopamine in drug abuse and addiction: results of imaging studies and treatment implications

scientific article

Dopamine increases in striatum do not elicit craving in cocaine abusers unless they are coupled with cocaine cues.

scientific article

Dopamine transporters in striatum correlate with deactivation in the default mode network during visuospatial attention

scientific article

Dynamic Precision Phenotyping Reveals Mechanism of Crop Tolerance to Root Herbivory

scientific article

Dynamic functional imaging of brain glucose utilization using fPET-FDG.

scientific article

Effects of alcohol detoxification on dopamine D2 receptors in alcoholics: a preliminary study

scientific article published in December 2002

Effects of cell phone radiofrequency signal exposure on brain glucose metabolism

scientific article

Effects of expectation on the brain metabolic responses to methylphenidate and to its placebo in non-drug abusing subjects

scientific article

Effects of low-field magnetic stimulation on brain glucose metabolism

scientific article

Effects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications

scientific article

Enhanced resting activity of the oral somatosensory cortex in obese subjects

scientific article published in July 2002

Enhanced striatal dopamine release during food stimulation in binge eating disorder

scientific article

Evaluating dopamine reward pathway in ADHD: clinical implications

scientific article

Evaluation of 6-([(18)F]fluoroacetamido)-1-hexanoicanilide for PET imaging of histone deacetylase in the baboon brain

scientific article

Evaluation of positron emission tomography as a method to visualize subsurface microbial processes.

scientific article published on 18 January 2012

Evidence for reduced arterial plasma input, prolonged lung retention and reduced lung monoamine oxidase in smokers

scientific article published in July 2005

Evidence of gender differences in the ability to inhibit brain activation elicited by food stimulation

scientific article

Evidence that brain MAO A activity does not correspond to MAO A genotype in healthy male subjects

scientific article published on 04 December 2006

Evidence that formulations of the selective MAO-B inhibitor, selegiline, which bypass first-pass metabolism, also inhibit MAO-A in the human brain

scientific article

Evidence that methylphenidate enhances the saliency of a mathematical task by increasing dopamine in the human brain

scientific article

Evidence that sleep deprivation downregulates dopamine D2R in ventral striatum in the human brain

scientific article

Evidence that the methylation state of the monoamine oxidase A (MAOA) gene predicts brain activity of MAO A enzyme in healthy men.

scientific article

Expectation effects on brain dopamine responses to methylphenidate in cocaine use disorder

article

Expectation enhances the regional brain metabolic and the reinforcing effects of stimulants in cocaine abusers.

scientific article published in December 2003

Exposure to appetitive food stimuli markedly activates the human brain

scientific article published in April 2004

Fast uptake and long-lasting binding of methamphetamine in the human brain: comparison with cocaine

scientific article published on 22 July 2008

Gastric distention activates satiety circuitry in the human brain

scientific article

Gastric stimulation in obese subjects activates the hippocampus and other regions involved in brain reward circuitry

scholarly article

Gene x disease interaction on orbitofrontal gray matter in cocaine addiction

scientific article

Genomic features of the human dopamine transporter gene and its potential epigenetic States: implications for phenotypic diversity

scientific article

Genotype and ancestry modulate brain's DAT availability in healthy humans

scientific article

High levels of dopamine D2 receptors in unaffected members of alcoholic families: possible protective factors

scientific article published in September 2006

Histone deacetylase inhibitor, MS-275, exhibits poor brain penetration: PK studies of [C]MS-275 using Positron Emission Tomography

scientific article

Human keratinocytes have two interconvertible modes of proliferation.

scientific article

Hyperstimulation of striatal D2 receptors with sleep deprivation: Implications for cognitive impairment

scientific article published on 20 January 2009

Identification and characterization of putative methylation targets in the MAOA locus using bioinformatic approaches

scientific article

Image-guided synthesis reveals potent blood-brain barrier permeable histone deacetylase inhibitors.

scientific article

Imaging of brain dopamine pathways: implications for understanding obesity

scientific article

Imaging the addicted human brain

scientific article

Imaging the effects of methylphenidate on brain dopamine: new model on its therapeutic actions for attention-deficit/hyperactivity disorder

scientific article

Imaging the norepinephrine transporter in humans with (S,S)-[11C]O-methyl reboxetine and PET: problems and progress.

scientific article published on 8 June 2007

In vivo comparative imaging of dopamine D2 knockout and wild-type mice with (11)C-raclopride and microPET.

scientific article published on November 2002

In vivo imaging of brain aromatase in female baboons: [11C]vorozole kinetics and effect of the menstrual cycle

scientific article published in November 2013

Induced magnetic force in human heads exposed to 4 T MRI.

scientific article

Inhibition of food craving is a metabolically active process in the brain in obese men

scientific article published on 18 November 2019

Initial and subsequent approach for the synthesis of 18FDG

scientific article (publication date: 2002)

Inverse association between BMI and prefrontal metabolic activity in healthy adults

scientific article published on 23 October 2008

Investigation of SN2 [11C]cyanation for base-sensitive substrates: an improved radiosynthesis of L-[5-11C]-glutamine.

scientific article published on 10 December 2014

Is fetal brain monoamine oxidase inhibition the missing link between maternal smoking and conduct disorders?

scientific article published on May 2008

Kinetic analysis of [11C]vorozole binding in the human brain with positron emission tomography

scientific article published on 01 January 2014

Long-term stimulant treatment affects brain dopamine transporter level in patients with attention deficit hyperactive disorder

scientific article

Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors

scientific article published on 13 June 2008

Low doses of alcohol substantially decrease glucose metabolism in the human brain

scientific article published on 8 August 2005

Low monoamine oxidase B in peripheral organs in smokers

scientific article

Maternal and fetal 11C-cocaine uptake and kinetics measured in vivo by combined PET and MRI in pregnant nonhuman primates.

scientific article

Maternal-fetal in vivo imaging: a combined PET and MRI study.

scientific article published in September 2003

Methylphenidate attenuates limbic brain inhibition after cocaine-cues exposure in cocaine abusers

scientific article

Methylphenidate decreased the amount of glucose needed by the brain to perform a cognitive task

scientific article

Methylphenidate-elicited dopamine increases in ventral striatum are associated with long-term symptom improvement in adults with attention deficit hyperactivity disorder

scientific article

MicroPET imaging in an animal model of anorexia nervosa

scientific article published in August 2005

Modeling and analysis of PET studies with norepinephrine transporter ligands: the search for a reference region.

scientific article published in July 2005

Moderate doses of alcohol disrupt the functional organization of the human brain

scientific article published on 15 February 2008

Monoamine oxidase A imaging in peripheral organs in healthy human subjects

scientific article

Monoamine oxidase and cigarette smoking.

scientific article

Monoamine oxidase: radiotracer chemistry and human studies

scientific article

Monoamine oxidase: radiotracer development and human studies

scientific article

Neural mechanisms of anger regulation as a function of genetic risk for violence

scientific article

New Repeat Polymorphism in the AKT1 Gene Predicts Striatal Dopamine D2/D3 Receptor Availability and Stimulant-Induced Dopamine Release in the Healthy Human Brain

scientific article published on 17 April 2017

New-generation radiotracers for nAChR and NET.

scientific article

Nicotine blocks brain estrogen synthase (aromatase): in vivo positron emission tomography studies in female baboons

scientific article

Nuclear medicine and chemistry

scientific article published on 01 January 2002

One-pot, direct incorporation of [11C]CO2 into carbamates

scientific article published on January 2009

Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology

scientific article published on October 2008

PET Studies of the Effect of the Antidepressant Drugs Nefazodone or Paroxetine on [11C]Raclopride Binding in Human Brain ⬇️

scientific article published on July 1, 1999

PET imaging in clinical drug abuse research

scientific article published in January 2005

PET imaging of monoamine oxidase B in peripheral organs in humans.

scientific article published in October 2002

PET imaging of thin objects: measuring the effects of positron range and partial-volume averaging in the leaf of Nicotiana tabacum.

scientific article published on 27 October 2010

PET studies of d-methamphetamine pharmacokinetics in primates: comparison with l-methamphetamine and ( --)-cocaine

scientific article published on 14 September 2007

Partial recovery of brain metabolism in methamphetamine abusers after protracted abstinence

scientific article published in February 2004

Pharmacokinetics of the potent hallucinogen, salvinorin A in primates parallels the rapid onset and short duration of effects in humans.

scientific article published on 15 March 2008

Polymer-supported organotin reagent for prosthetic group labeling of biological macromolecules with radioiodine

scientific article published on 10 February 2011

Positron Emission Tomography (PET) and Graphical Kinetic Data Analysis of the Dopamine Neurotransmitter System: An Exercise for an Undergraduate Laboratory Course

scientific article

Positron emission tomography and single-photon emission computed tomography in substance abuse research

scientific article

Potential contribution of aromatase inhibition to the effects of nicotine and related compounds on the brain

scientific article (publication date: 2012)

Preclinical evaluation of the first adenosine A receptor partial agonist radioligand for positron emission tomography (PET) imaging

article

Predominance of D2 receptors in mediating dopamine's effects in brain metabolism: effects of alcoholism.

scientific article published on March 2013

Profound decreases in dopamine release in striatum in detoxified alcoholics: possible orbitofrontal involvement

scientific article published in November 2007

Quantitation, regional vulnerability, and kinetic modeling of brain glucose metabolism in mild Alzheimer's disease

scientific article published on 4 April 2007

Radiolabelling and positron emission tomography of PT70, a time-dependent inhibitor of InhA, the Mycobacterium tuberculosis enoyl-ACP reductase

scientific article

Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brain

scientific article

Radiosynthesis and bioimaging of the tuberculosis chemotherapeutics isoniazid, rifampicin and pyrazinamide in baboons

scientific article

Radiosynthesis and biological evaluation of a novel enoyl-ACP reductase inhibitor for Staphylococcus aureus

scientific article

Radiosynthesis of 3-indolyl[1-¹¹C]acetic acid for phyto-PET-imaging: an improved production procedure and formulation method.

scientific article published on 27 May 2014

Radiotracer chemistry in 2002.

scientific article published in January 2003

Radiotracers for positron emission tomography imaging

scientific article

Reactions to media violence: it's in the brain of the beholder

scientific article

Recovery of dopamine transporters with methamphetamine detoxification is not linked to changes in dopamine release

scientific article published on 21 July 2015

Reduced metabolism in brain "control networks" following cocaine-cues exposure in female cocaine abusers

scientific article

Reinvestigation of the synthesis and evaluation of [N-methyl-(11)C]vorozole, a radiotracer targeting cytochrome P450 aromatase

scientific article published on April 2009

Relationship between blockade of dopamine transporters by oral methylphenidate and the increases in extracellular dopamine: therapeutic implications

scientific article

Relationship between ethanol-induced changes in brain regional metabolism and its motor, behavioural and cognitive effects

scientific article published in January 2004

Relationship of estrogen synthesis capacity in the brain with obesity and self-control in men and women

scientific article published on 31 August 2020

Reply to Burgard: Gender differences in eating behaviors and obesity.

scholarly article

Reproducibility of 11C-raclopride binding in the rat brain measured with the microPET R4: effects of scatter correction and tracer specific activity.

scientific article published in May 2003

Reproducibility of intraperitoneal 2-deoxy-2-[18F]-fluoro-D-glucose cerebral uptake in rodents through time

scientific article published in January 2006

Reversible inhibitors of monoamine oxidase-A (RIMAs): robust, reversible inhibition of human brain MAO-A by CX157.

scientific article

Role of dopamine in the therapeutic and reinforcing effects of methylphenidate in humans: results from imaging studies

scientific article

Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies

scientific article

Selegiline potentiates cocaine-induced increases in rodent nucleus accumbens dopamine

scientific article

Severity of neuropsychological impairment in cocaine and alcohol addiction: association with metabolism in the prefrontal cortex.

scientific article published in January 2004

Similarity between obesity and drug addiction as assessed by neurofunctional imaging: a concept review

scientific article

Sleep deprivation decreases binding of [11C]raclopride to dopamine D2/D3 receptors in the human brain.

scientific article published on August 2008

Stimulant-induced enhanced sexual desire as a potential contributing factor in HIV transmission

scientific article

Strategy for the formation of parametric images under conditions of low injected radioactivity applied to PET studies with the irreversible monoamine oxidase A tracers [11C]clorgyline and deuterium-substituted [11C]clorgyline

scientific article published in November 2002

Studies with Differentially Labeled [11C]Cocaine, [11C]Norcocaine, [11C]Benzoylecgonine, and [11C]-and 4′-[18F]Fluorococaine to Probe the Extent to Which [11C]Cocaine Metabolites Contribute to PET Images of the Baboon Brain

article

Synthesis and PET studies of [(11)C-cyano]letrozole (Femara), an aromatase inhibitor drug

scientific article

Synthesis and positron emission tomography studies of C-11-labeled isotopomers and metabolites of GTS-21, a partial alpha7 nicotinic cholinergic agonist drug.

scientific article

Synthesis and positron emission tomography studies of carbon-11-labeled imatinib (Gleevec).

scientific article

Synthesis of l-[4-11 C]Asparagine by Ring-Opening Nucleophilic 11 C-Cyanation Reaction of a Chiral Cyclic Sulfamidate Precursor.

scientific article published on 5 March 2018

Synthesis of structurally identical fluorine-18 and iodine isotope labeling compounds for comparative imaging

scientific article published in March 2003

The MAO-A genotype does not modulate resting brain metabolism in adults

scientific article published on 15 August 2008

The Use of Alternative Forms of Graphical Analysis to Balance Bias and Precision in PET Images ⬇️

scientific article published on September 1, 2010

The addicted human brain viewed in the light of imaging studies: brain circuits and treatment strategies

scientific article

The addicted human brain: insights from imaging studies ⬇️

scientific article published on May 1, 2003

The design and performance of a portable handheld (11)CO2 delivery system.

scientific article published on 22 September 2014

The orbitofrontal cortex in methamphetamine addiction: involvement in fear

scientific article

The role of dopamine in motivation for food in humans: implications for obesity

scientific article

The slow and long-lasting blockade of dopamine transporters in human brain induced by the new antidepressant drug radafaxine predict poor reinforcing effects

scientific article

Therapeutic doses of buspirone block D3 receptors in the living primate brain.

scientific article published on 28 March 2014

Total cyanide mass measurement with micro-ion selective electrode for determination of specific activity of carbon-11 cyanide.

scientific article published on 25 April 2015

Translational neuroimaging: positron emission tomography studies of monoamine oxidase.

scientific article

Trialing collaborative nursing Models of Care: the impact of change

scientific article published on 01 June 2006

Unique distribution of aromatase in the human brain: In vivo studies with PET and [N‐methyl‐11C]vorozole ⬇️

scientific article published on November 1, 2010

What is in a word? No versus Yes differentially engage the lateral orbitofrontal cortex

scientific article

Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET.

scientific article

[(11)C]PR04.MZ, a promising DAT ligand for low concentration imaging: Synthesis, efficient (11)C-O-methylation and initial small animal PET studies.

scientific article

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