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List of works by Mikko Metsä-Ketelä

A pharmaceutical model for the molecular evolution of microbial natural products

scientific article published on 22 November 2019

Activation of microbial secondary metabolic pathways: Avenues and challenges

scientific article published on 12 September 2018

Artificial Reconstruction of Two Cryptic Angucycline Antibiotic Biosynthetic Pathways

scientific article published on 01 September 2007

Biosynthetic conclusions from the functional dissection of oxygenases for biosynthesis of actinorhodin and related Streptomyces antibiotics.

scientific article published on April 2013

Characterization and overproduction of cell-associated cholesterol oxidase ChoD from Streptomyces lavendulae YAKB-15

scientific article published on 14 August 2019

Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis.

scientific article published in October 2008

Chemoenzymatic synthesis of novel C-ribosylated naphthoquinones

scientific article published on 19 September 2013

Discovery of a two-component monooxygenase SnoaW/SnoaL2 involved in nogalamycin biosynthesis

scientific article published on 01 May 2012

Discovery of the Showdomycin Gene Cluster from Streptomyces showdoensis ATCC 15227 Yields Insight into the Biosynthetic Logic of C-Nucleoside Antibiotics

scientific article published on 18 April 2017

Effective Antibiofilm Polyketides against Staphylococcus aureus from the Pyranonaphthoquinone Biosynthetic Pathways of Streptomyces Species ⬇️

scientific article published on 20 July 2015

Enzymatic Synthesis of the C-Glycosidic Moiety of Nogalamycin R

scientific article published on 20 August 2018

Evolution inspired engineering of antibiotic biosynthesis enzymes.

scientific article published on 27 April 2017

Evolution-guided engineering of non-heme iron enzymes involved in nogalamycin biosynthesis

scientific article published on 26 December 2019

Evolutionary Trajectories for the Functional Diversification of Anthracycline Methyltransferases

scientific article published on 23 April 2019

Flavoprotein hydroxylase PgaE catalyzes two consecutive oxygen-dependent tailoring reactions in angucycline biosynthesis

scientific article published on 27 May 2011

Formation of 5-Hydroxy-3-methoxy-1,4-naphthoquinone and 8-Hydroxy-4-methoxy-1,2-naphthoquinone from Juglone

scientific article published on 23 September 2012

Identification of Late-Stage Glycosylation Steps in the Biosynthetic Pathway of the Anthracycline Nogalamycin

scientific article published on 25 November 2011

Insights into Complex Oxidation during BE-7585A Biosynthesis: Structural Determination and Analysis of the Polyketide Monooxygenase BexE.

scientific article published on 27 January 2016

Ketosynthase III as a gateway to engineering the biosynthesis of antitumoral benastatin derivatives.

scientific article

Laboratory course on Streptomyces genetics and secondary metabolism

scientific article published on 18 May 2016

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

Molecular evolution of the bacterial pseudouridine-5'-phosphate glycosidase protein family

scientific article published on 25 August 2014

Structure-based engineering of angucyclinone 6-ketoreductases

scientific article

Tailoring enzymes involved in the biosynthesis of angucyclines contain latent context-dependent catalytic activities.

scientific article

The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases

scientific article published on 04 February 2021

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