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List of works by Ioakim Spyridopoulos

A comparative analysis of British and American Society of Echocardiography recommendations for the assessment of left ventricular diastolic function

scientific article published on 01 December 2018

Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity.

scientific article published on 21 September 2009

Acute mountain sickness is not related to cerebral blood flow: a decompression chamber study

scientific article published on 01 May 1999

Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells.

scientific article published on 12 February 2004

Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism

scientific article published on 4 August 2014

CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine.

scientific article published on 21 June 2018

CMV seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study

scientific article published on 22 December 2015

CMV-independent increase in CD27-CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians

scientific article published on 21 January 2020

Caffeine enhances endothelial repair by an AMPK-dependent mechanism

scientific article published on 28 August 2008

Can telomere length predict cardiovascular risk?

scientific article published in The Lancet

Clearance of senescent cells during cardiac ischemia-reperfusion injury improves recovery

scientific article published on 29 September 2020

Comparison of the Seattle heart failure model and cardiopulmonary exercise capacity for prediction of death in patients with chronic ischemic heart failure and intracoronary progenitor cell application.

scientific article published on 3 February 2013

Complete revascularization in patients undergoing multivessel PCI is an independent predictor of improved long-term survival

scientific article published on 01 June 2010

Dietary restriction ameliorates haematopoietic ageing independent of telomerase, whilst lack of telomerase and short telomeres exacerbates the ageing phenotype.

scientific article published on 17 July 2014

Differences in immune responses between CMV-seronegative and -seropositive patients with myocardial ischemia and reperfusion.

scientific article published on March 2015

Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells.

scientific article

Effect of ciclosporin on safety, lymphocyte kinetics and left ventricular remodelling in acute myocardial infarction

scientific article published on 17 February 2020

Exercise, telomerase activity, and cardiovascular disease prevention

scientific article published on 01 January 2019

Favorable long-term survival in patients undergoing multivessel-PCI compared to predicted prognosis of CABG estimated by EuroSCORE: procedural and clinical determinants of long-term outcome.

scientific article published on 2 September 2009

Favorable long-term survival in patients undergoing stent PCI of unprotected left main coronary artery compared to predicted short-term prognosis of CABG estimated by EuroSCORE: clinical determinants of long-term outcome

scientific article published on 01 August 2009

Functionally novel tumor necrosis factor-alpha-modulated CHR-binding protein mediates cyclin A transcriptional repression in vascular endothelial cells.

scientific article published in August 2002

HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes

scientific article published on 3 April 2003

High-throughput 13-parameter immunophenotyping identifies shifts in the circulating T-cell compartment following reperfusion in patients with acute myocardial infarction.

scientific article

Idiopathic (unexplained) pulmonary embolism is associated with an impaired prognosis compared to other entities of pulmonary embolism.

scientific article published in January 2010

Impact of interventional strategy for unprotected left main coronary artery percutaneous coronary intervention on long-term survival

scientific article published on 02 May 2012

Impact of thrombus aspiration during primary percutaneous coronary intervention on mortality in ST-segment elevation myocardial infarction

scientific article published on 17 September 2012

Interventions to slow cardiovascular aging: Dietary restriction, drugs and novel molecules.

scientific article published on 25 June 2017

Is telomerase a potential target for vascular rejuvenation?

scientific article

Ivabradine therapy to unmask heart rate-independent effects of β-blockers on pulse wave reflections

scientific article published on 18 February 2014

Lymphocyte Communication in Myocardial Ischemia/Reperfusion Injury

scientific article published on 23 December 2016

Microvascular dysfunction and pulse wave reflection characterize different vascular pathologies in patients at cardiovascular risk.

scientific article published on May 2012

Microvessels of the heart: Formation, regeneration, and dysfunction.

scientific article

Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage

scientific article published on 5 March 2009

Molecular mechanisms and therapy of cardiovascular ageing

scientific article published on 10 June 2018

Mortality outcome of out-of-hours primary percutaneous coronary intervention in the current era ⬇️

scientific article published on September 4, 2012

Myocardial ischemia and reperfusion leads to transient CD8 immune deficiency and accelerated immunosenescence in CMV-seropositive patients

scientific article

Non-coding RNA regulation of T cell biology: Implications for age-associated cardiovascular diseases.

scientific article published on 23 June 2017

Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase.

scientific article published on October 2008

Overcoming Heparin-Associated RT-qPCR Inhibition and Normalization Issues for microRNA Quantification in Patients with Acute Myocardial Infarction

scientific article published on 11 June 2018

Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction

scientific article published on 28 March 2019

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Restoration of E2F expression rescues vascular endothelial cells from tumor necrosis factor-alpha-induced apoptosis

scientific article published on 01 December 1998

Risk stratification following complex PCI: clinical versus anatomical risk stratification including "post PCI residual SYNTAX-score" as quantification of incomplete revascularization.

scientific article published in February 2013

Role of N-terminal pro-brain natriuretic peptide and cystatin C to estimate renal function in patients with and without heart failure.

scientific article

Role of endothelial nitric oxide synthase in endothelial cell migration

scientific article published on 01 May 1999

Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure

scientific article

Senescent cytotoxic T cells in acute myocardial infarction: innocent bystanders or the horsemen of apocalypse?

scientific article published on 22 September 2014

Shock-index as a novel predictor of long-term outcome following primary percutaneous coronary intervention

scientific article published on 25 November 2014

Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor

scientific article

Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.

scientific article published in November 2004

T lymphocytes and fractalkine contribute to myocardial ischemia/reperfusion injury in patients.

scientific article

Telomerase Activation to Reverse Immunosenescence in Elderly Patients With Acute Coronary Syndrome: Protocol for a Randomized Pilot Trial

scientific article published on 23 September 2020

Telomerase Mediates Lymphocyte Proliferation but Not the Atherosclerosis-Suppressive Potential of Regulatory T-Cells.

scientific article published on 29 March 2018

Telomere Length in Cardiovascular Disease: New Challenges in Measuring This Marker of Cardiovascular Aging ⬇️

scientific article published on November 1, 2011

Telomere gap between granulocytes and lymphocytes is a determinant for hematopoetic progenitor cell impairment in patients with previous myocardial infarction.

scientific article

Telomere length predicts cardiovascular disease

scientific article published in the British Medical Journal

Telomere length-heterogeneity among myeloid cells is a predictor for chronological ageing.

scientific article published on 25 February 2009

The evidence base for revascularisation of chronic total occlusions.

scientific article

The initial slope of the VCO2/VO2-curve (s1) in cardiopulmonary exercise testing is a strong and independent predictor of outcome in patients with previous myocardial infarction.

scientific article published on 11 August 2008

The role of arginine vasopressin in myocardial infarction and reperfusion

scientific article published on 25 September 2019

The secret life of nonclassical monocytes.

scientific article published on 27 October 2017

Understanding the molecular and cellular basis of therapeutic stem and progenitor cell transplantation for tissue revascularization

scientific article published on 01 January 2005

Vascular endothelial growth factor-C (VEGF-C/VEGF-2) promotes angiogenesis in the setting of tissue ischemia

scientific article published on August 1998

[Pacemaker quiz, 12th part]

scientific article published on 01 June 2006

β-Blockers and ivabradine differentially affect cardiopulmonary function and left ventricular filling index.

scientific article published on 19 December 2015

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