List of works - Emmanuelle Liaudet-Coopman

A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

scientific article published on 15 April 2021

A mutated cathepsin-D devoid of its catalytic activity stimulates the growth of cancer cells.

scientific article published in October 2001

Alteration of cathepsin D trafficking induced by hypoxia and extracellular acidification in MCF-7 breast cancer cells

scientific article published on 12 November 2015

BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization

scientific journal article

Catalytically inactive human cathepsin D triggers fibroblast invasive growth

scientific article

Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis ⬇️

scientific article published on November 14, 2011

Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis

scientific article

Cathepsin-D affects multiple tumor progression steps in vivo: proliferation, angiogenesis and apoptosis

scientific article published on 01 August 2002

Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis

scientific article

Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells.

scientific article published on August 2002

Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies

scientific article published on 04 February 2019

LRP1 receptor controls adipogenesis and is up-regulated in human and mouse obese adipose tissue.

scientific article

Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells

scientific article

Overexpression of both catalytically active and -inactive cathepsin D by cancer cells enhances apoptosis-dependent chemo-sensitivity

scientific article

Pathophysiological functions of cathepsin D: Targeting its catalytic activity versus its protein binding activity?

scientific article published on 21 May 2010

Phorbol ester-induced transcription of a fibroblast growth factor-binding protein is modulated by a complex interplay of positive and negative regulatory promoter elements.

scientific article published on July 1998

Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.

scientific article

Processing of human cathepsin D is independent of its catalytic function and auto-activation: involvement of cathepsins L and B.

scientific article published on March 2006

Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment.

scientific article

Proteomic analysis of vascular smooth muscle cells in physiological condition and in pulmonary arterial hypertension: Toward contractile versus synthetic phenotypes.

scientific article published on 25 July 2016

List of works by Emmanuelle Liaudet-Coopman

A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

A mutated cathepsin-D devoid of its catalytic activity stimulates the growth of cancer cells.

Alteration of cathepsin D trafficking induced by hypoxia and extracellular acidification in MCF-7 breast cancer cells

BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization

Catalytically inactive human cathepsin D triggers fibroblast invasive growth

Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis ⬇️

Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis

Cathepsin-D affects multiple tumor progression steps in vivo: proliferation, angiogenesis and apoptosis

Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis

Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells.

Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies

LRP1 receptor controls adipogenesis and is up-regulated in human and mouse obese adipose tissue.

Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells

Overexpression of both catalytically active and -inactive cathepsin D by cancer cells enhances apoptosis-dependent chemo-sensitivity

Pathophysiological functions of cathepsin D: Targeting its catalytic activity versus its protein binding activity?

Phorbol ester-induced transcription of a fibroblast growth factor-binding protein is modulated by a complex interplay of positive and negative regulatory promoter elements.

Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.

Processing of human cathepsin D is independent of its catalytic function and auto-activation: involvement of cathepsins L and B.

Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment.

Proteomic analysis of vascular smooth muscle cells in physiological condition and in pulmonary arterial hypertension: Toward contractile versus synthetic phenotypes.