Search filters

List of works by Daniel A Harki

4-Cyanoindole-2'-deoxyribonucleoside (4CIN): A Universal Fluorescent Nucleoside Analogue

scientific article published on 10 July 2018

A redox economical synthesis of bioactive 6,12-guaianolides.

scientific article published on 10 May 2013

APOBEC Enzymes as Targets for Virus and Cancer Therapy.

scientific article published on 14 November 2017

Alkyne Ligation Handles: Propargylation of Hydroxyl, Sulfhydryl, Amino, and Carboxyl Groups via the Nicholas Reaction

scientific article published on 29 August 2016

Arsenic exposure accelerates atherogenesis in apolipoprotein E-/-mice

journal article published in 2003

Bicyclic Cyclohexenones as Inhibitors of NF-κB Signaling ⬇️

scientific article published on May 11, 2012

Catch and Release DNA Decoys: Capture and Photochemical Dissociation of NF-κB Transcription Factors.

scientific article published on 7 April 2016

Cell surface markers of cancer stem cells: diagnostic macromolecules and targets for drug delivery

scientific article published on April 2013

Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions

scientific article (publication date: 20 December 2016)

Determinants of Oligonucleotide Selectivity of APOBEC3B

scientific article published on 10 September 2018

Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle

scientific article

Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA

scientific article published on 19 December 2019

EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer

scientific article

First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G

scientific article

Helenalin Analogues Targeting NF-κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles.

scientific article

Immunodetection of human topoisomerase I-DNA covalent complexes

scientific article

Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2'-Deoxyzebularine Analogues

scientific article published on 28 November 2018

Inhibition of guanosine monophosphate synthetase by the substrate enantiomer L-XMP.

scientific article published on 23 October 2012

Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues.

scientific article

Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue.

scientific article published on 8 August 2007

Molecular Basis for the N-Terminal Bromodomain-and-Extra-Terminal-Family Selectivity of a Dual Kinase-Bromodomain Inhibitor

scientific article published on 16 October 2018

Oxidative Reactivities of 2-Furylquinolines: Ubiquitous Scaffolds in Common High-Throughput Screening Libraries.

scientific article published on 11 September 2015

Parthenolide prodrug LC-1 slows growth of intracranial glioma.

scientific article published on 25 April 2015

Rapid, Microwave Accelerated Synthesis of [1,2,4]Triazolo[3,4-b][1,3,4]oxadiazoles from 4-Acylamino-1,2,4-Triazoles.

scientific article published on 29 July 2016

Reassessing APOBEC3G Inhibition by HIV-1 Vif-Derived Peptides

scientific article published on 22 November 2016

SN-38 conjugated gold nanoparticles activated by Ewing sarcoma specific mRNAs exhibit in vitro and in vivo efficacy.

scientific article published on 7 February 2018

Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers.

scientific article published in October 2017

Small-molecule APOBEC3G DNA cytosine deaminase inhibitors based on a 4-amino-1,2,4-triazole-3-thiol scaffold.

scientific article

Solution-phase synthesis of pyrrole-imidazole polyamides

scientific article published on May 2009

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.

scientific article published on 19 December 2016

Structural insights into mechanisms of catalysis and inhibition in Norwalk virus polymerase

scientific article

Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues.

scientific article

Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.

scientific article

Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.

scientific article

Synthesis of Guaianolide Analogues with a Tunable α-Methylene-γ-lactam Electrophile and Correlating Bioactivity with Thiol Reactivity

scientific article published on 17 November 2020

Synthesis of a peptide-universal nucleotide antigen: towards next-generation antibodies to detect topoisomerase I-DNA covalent complexes.

scientific article

Targeting NF-κB p65 with a Helenalin Inspired Bis-electrophile.

scientific article published on 28 November 2016

The Binding Interface between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches

scientific article

Paulina is supported by:

About Paulina

Help