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List of works by Wolfgang F. Richter

6-Alkoxy-5-aryl-3-pyridinecarboxamides, a new series of bioavailable cannabinoid receptor type 1 (CB1) antagonists including peripherally selective compounds

scientific article published on 20 November 2013

Analysis of erlotinib and its metabolites in rat tissue sections by MALDI quadrupole time-of-flight mass spectrometry.

scientific article

Animal pharmacokinetics and interspecies scaling of Ro 25-6833 and related (lactamylvinyl)cephalosporins

scientific article published on 01 April 1998

Are Biotransformation Studies of Therapeutic Proteins Needed? Scientific Considerations and Technical Challenges

scientific article published on 01 December 2019

Biotherapeutics in non-clinical development: Strengthening the interface between safety, pharmacokinetics-pharmacodynamics and manufacturing.

scientific article published on 16 January 2018

CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies

scientific article published on 01 May 2018

Design of experiment (DOE) methods maximize information from a minimal number of animals in special cases of preclinical bioavailability testing

scientific article published in January 2003

Gantenerumab: a novel human anti-Aβ antibody demonstrates sustained cerebral amyloid-β binding and elicits cell-mediated removal of human amyloid-β

scientific article

Hematopoietic cells as site of first-pass catabolism after subcutaneous dosing and contributors to systemic clearance of a monoclonal antibody in mice

scientific article published on 5 April 2018

High-Throughput, Sensitive LC-MS Quantification of Biotherapeutics and Biomarkers Using Antibody-Free, Peptide-Level, Multiple-Mechanism Enrichment via Strategic Regulation of pH and Ionic and Solvent Strengths

scientific article published on 15 February 2019

Immunogenicity, Inflammation, and Lipid Accumulation in Cynomolgus Monkeys Infused with a Lipidated Tetranectin-ApoA-I Fusion Protein

scientific article published on 18 January 2016

In Vivo Biotransformation of the Fusion Protein Tetranectin-Apolipoprotein A1 Analyzed by Ligand-Binding Mass Spectrometry Combined with Quantitation by ELISA.

scientific article published on 18 November 2016

Mechanistic determinants of biotherapeutics absorption following SC administration.

scientific article

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration.

scientific article

Neonatal Immune Tolerance Induction to Allow Long-Term Studies With an Immunogenic Therapeutic Monoclonal Antibody in Mice

scientific article published on 24 November 2015

New challenges and opportunities in nonclinical safety testing of biologics

scientific article published on 19 April 2014

Non-clinical Safety Evaluation of Biotherapeutics - Challenges, Opportunities and new Insights

scientific article published on 27 August 2016

Non-clinical pharmacokinetic/pharmacodynamic and early clinical studies supporting development of a novel subcutaneous formulation for the monoclonal antibody rituximab

scientific article published on 22 January 2014

Potential errors in the volume of distribution estimation of therapeutic proteins composed of differently cleared components

scientific article published on 21 July 2011

Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody

scientific article published on 24 June 2020

Reproductive and developmental toxicology studies with gantenerumab in PS2APP transgenic mice.

scientific article published on 25 July 2017

Subcutaneous Administration of Biotherapeutics: An Overview of Current Challenges and Opportunities

scientific article published on 01 October 2018

Subcutaneous absorption of biotherapeutics: knowns and unknowns.

scientific article published on 6 August 2014

Subcutaneous versus intravenous administration of rituximab: pharmacokinetics, CD20 target coverage and B-cell depletion in cynomolgus monkeys

scientific article (publication date: 2013)

The distribution pattern of radioactivity across different tissues in quantitative whole-body autoradiography (QWBA) studies.

scientific article published on 28 February 2006

The effects of interleukin-6 signal blockade on immune system, reproductive and skeletal development in juvenile mice.

scientific article published on 25 March 2013

Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis

scientific article published on 13 April 2017

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