Search filters

List of works by Mohamed Rahmani

A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia.

scientific article published on 29 May 2008

Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda -7/IL-24–mediated toxicity

scientific article published on May 9, 2011

Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overload

scientific article published on 27 March 2019

Co-administration of the mTORC1/TORC2 inhibitor INK128 and the Bcl-2/Bcl-xL antagonist ABT-737 kills human myeloid leukemia cells through Mcl-1 down-regulation and AKT inactivation.

scientific article

Coordinate PI3K pathway and Bcl-2 family disruption in AML.

scientific article published in December 2012

Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells

scientific article published on 20 March 2018

Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis

scientific article published on 25 April 2014

Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation

scientific article

Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.

scientific article published on 12 December 2012

Functional cooperation between JunD and NF-kappaB in rat hepatocytes.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Hepatocyte growth factor activates the AP-1 complex: a comparison between normal and transformed rat hepatocytes.

scientific article published on May 1999

Induction of Apoptosis in BCR/ABL+ Cells By Histone Deacetylase Inhibitors Involves Reciprocal Effects on the RAF/MEK/ERK and JNK Pathways

scientific article published on September 1, 2003

Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process

scientific article

On the organization of human T-cell receptor loci: log-periodic distribution of T-cell receptor gene segments

scientific article

PI3K/mTOR inhibition markedly potentiates HDAC inhibitor activity in NHL cells through BIM- and MCL-1-dependent mechanisms in vitro and in vivo

scientific article

Presence of distinct AP-1 dimers in normal and transformed rat hepatocytes under basal conditions and after epidermal growth factor stimulation

scientific article published on December 1, 1997

Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-κB-dependent process

scientific article published on October 16, 2003

Rational combination of dual PI3K/mTOR blockade and Bcl-2/-xL inhibition in AML.

scientific article

Studying the ShcD and ERK interaction under acute oxidative stress conditions in melanoma cells

scientific article published on 20 May 2019

Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin's lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms

scientific article

The NAE inhibitor pevonedistat interacts with the HDAC inhibitor belinostat to target AML cells by disrupting the DDR.

scientific article published on 5 February 2016

The development of MDA-7/IL-24 as a cancer therapeutic

scientific article published on August 21, 2010

The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells.

scientific article published in April 2004

mda-7/IL-24: A unique member of the IL-10 gene family promoting cancer-targeted toxicity

scientific article published on October 1, 2010