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List of works by Carolyn Bertozzi

(D)-Amino acid chemical reporters reveal peptidoglycan dynamics of an intracellular pathogen

scientific article published on 11 January 2013

5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice.

scientific article published in March 2006

5'-adenosinephosphosulfate lies at a metabolic branch point in mycobacteria

scientific journal article

A "traceless" Staudinger ligation for the chemoselective synthesis of amide bonds

scientific article published on July 2000

A 96-well dot-blot assay for carbohydrate sulfotransferases

scientific article published in August 2002

A Bioorthogonal Reaction of N-Oxide and Boron Reagents

scientific article published on 16 November 2015

A Comparative Study of Bioorthogonal Reactions with Azides

scientific article

A Decade of Bioorthogonal Chemistry ⬇️

scientific article published on September 20, 2011

A FRET-based fluorogenic phosphine for live-cell imaging with the Staudinger ligation

scientific article published on January 2008

A Fluorogenic Trehalose Probe for Tracking Phagocytosed Mycobacterium tuberculosis

scientific article published on 19 August 2020

A Meeting Full of Firsts

scientific article published on May 2015

A Model for Accelerating Patient-to-Bench Research

scientific article published in November 2017

A Mucin-Specific Protease Enables Molecular and Functional Analysis of Human Cancer-Associated Mucins

A Pictet-Spengler ligation for protein chemical modification

scientific article published on 13 December 2012

A Pragmatic Guide to Enrichment Strategies for Mass Spectrometry-based Glycoproteomics

scientific article published on 16 September 2020

A Season of Giving to Science

scientific article published on December 2016

A Sugar Cloak of Invisibility

scientific article published on 01 May 2019

A bioorthogonal quadricyclane ligation

scientific article

A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression.

scientific article published on 21 December 2017

A cell nanoinjector based on carbon nanotubes

scientific article

A chemical approach for identifying O-GlcNAc-modified proteins in cells

scientific article

A chemical approach to unraveling the biological function of the glycosylphosphatidylinositol anchor.

scholarly article

A chemical glycoproteomics platform reveals O-GlcNAcylation of mitochondrial voltage-dependent anion channel 2.

scientific article published on 10 October 2013

A chemical method for labeling lysine methyltransferase substrates.

scientific article published on 17 November 2010

A chemical reporter strategy to probe glycoprotein fucosylation

scientific article published on September 2006

A chemically synthesized version of the insect antibacterial glycopeptide, diptericin, disrupts bacterial membrane integrity

scientific article published on September 1999

A conserved mechanism for sulfonucleotide reduction

scientific article

A fluorogenic dye activated by the staudinger ligation

scientific article (publication date: 23 April 2003)

A fluorogenic screening platform enables directed evolution of an alkyne biosynthetic tool

scientific article published on 25 August 2016

A high-throughput assay for O-GlcNAc transferase detects primary sequence preferences in peptide substrates

scientific article published on 10 May 2007

A homologation approach to the synthesis of difluorinated cycloalkynes

scientific article published on 03 March 2014

A hydrophilic azacyclooctyne for Cu-free click chemistry

scientific article

A library approach to the generation of bisubstrate analogue sulfotransferase inhibitors

scientific article

A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells

scientific article

A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation

scientific article

A new approach to mineralization of biocompatible hydrogel scaffolds: an efficient process toward 3-dimensional bonelike composites

scientific article

A novel germline variant in CSF3R reduces N-glycosylation and exerts potent oncogenic effects in leukemia

scientific article published on 22 October 2018

A riboswitch-based inducible gene expression system for mycobacteria

scientific article (publication date: 2012)

A role for sulfation-desulfation in the uptake of bisphenol a into breast tumor cells

scientific article published on August 2006

A small-molecule modulator of poly-alpha 2,8-sialic acid expression on cultured neurons and tumor cells

scientific article

A small-molecule switch for Golgi sulfotransferases

scholarly article

A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems

scientific article

A strategy for functional proteomic analysis of glycosidase activity from cell lysates.

scientific article published in October 2004

A strategy for the selective imaging of glycans using caged metabolic precursors

scientific article

A sulfated metabolite produced by stf3 negatively regulates the virulence of Mycobacterium tuberculosis

scientific article

A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma

scientific article published on 10 September 2018

A visualizable chain-terminating inhibitor of glycosaminoglycan biosynthesis in developing zebrafish

scientific article

Achieving Gender Balance in the Chemistry Professoriate Is Not Rocket Science

scientific article published on April 2016

Acute modulation of mycobacterial cell envelope biogenesis by front-line TB drugs

scientific article

Advice for "Hunting Season".

scientific article published on December 2015

Aminooxy-, Hydrazide-, and Thiosemicarbazide-Functionalized Saccharides: Versatile Reagents for Glycoconjugate Synthesis ⬇️

scientific article published on October 16, 1998

An Acquired and Endogenous Glycocalyx Forms a Bidirectional "Don't Eat" and "Don't Eat Me" Barrier to Phagocytosis

scientific article published on 19 October 2020

An ELISA for selectins based on binding to a physiological ligand.

scientific article published in April 1997

An RNA-centric dissection of host complexes controlling flavivirus infection

scientific article published on 05 August 2019

An alpha-formylglycine building block for fmoc-based solid-phase peptide synthesis

scientific article published on January 2006

An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins

scientific article published on 17 August 2020

An expanded set of fluorogenic sulfatase activity probes

scientific article published on 24 April 2014

An inhibitor of O-glycosylation induces apoptosis in NIH3T3 cells and developing mouse embryonic mandibular tissues

scientific article published on September 2004

An inhibitor of O-glycosylation induces apoptosis in NIH3T3 cells and developing mouse embryonic mandibular tissues

article published in 2008

An inhibitor of the human UDP-GlcNAc 4-epimerase identified from a uridine-based library: a strategy to inhibit O-linked glycosylation

scientific article published in January 2002

Analyzing nested experimental designs-A user-friendly resampling method to determine experimental significance

scientific article published on 02 May 2022

Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication

scientific article published in 2022

Antibody detection by agglutination-PCR (ADAP) enables early diagnosis of HIV infection by oral fluid analysis

scientific article published on 22 January 2018

Atoms out of Blobs: CryoEM Takes the Nobel Prize in Chemistry

scientific article published in October 2017

Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

scientific article published on 27 July 2020

Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

scientific article published on 01 February 2020

Azido sialic acids can modulate cell-surface interactions

scientific article

Back to the Lecture

scientific article published on August 2016

Biocompatible carbon nanotubes generated by functionalization with glycodendrimers

scientific article

Bioluminescent probes of sulfatase activity

scientific article

Biomimetic engineering of carbon nanotubes by using cell surface mucin mimics

scientific article published in November 2004

Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics

scientific article

Bioorthogonal chemistry: fishing for selectivity in a sea of functionality

scientific article

Biosynthesis and Regulation of Sulfomenaquinone, a Metabolite Associated with Virulence in Mycobacterium tuberculosis

scientific article

Biosynthesis of L-selectin ligands: sulfation of sialyl Lewis x-related oligosaccharides by a family of GlcNAc-6-sulfotransferases

scientific article published on May 2001

Biosynthetic incorporation of unnatural sialic acids into polysialic acid on neural cells

scientific article

Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells.

scientific article published on January 2009

Bringing chemistry to life

scientific article

Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells

scientific article published on 09 April 2020

C-Glycosyl Aldehydes: Synthons for C-Linked Disaccharides ⬇️

scientific article published on March 8, 1996

CD22 blockade restores homeostatic microglial phagocytosis in ageing brains

scientific article published on 03 April 2019

CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity

scientific article published on 26 August 2019

CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum.

scientific article published on 2 June 2015

Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis patient bioaerosols

scientific article published in February 2021

Carbohydrate sulfotransferases of the GalNAc/Gal/GlcNAc6ST family

scientific article

Carbohydrate sulfotransferases: mediators of extracellular communication

scientific article

Cell surface glycoproteomic analysis of prostate cancer-derived PC-3 cells

scientific article published on 18 May 2011

Cell type-selective secretome profiling in vivo

scientific article published on 16 November 2020

Cellular microfabrication: observing intercellular interactions using lithographically-defined DNA capture sequences

scientific article

Central metabolism in Mycobacterium smegmatis during the transition from O2-rich to O2-poor conditions as studied by isotopomer-assisted metabolite analysis

scientific article published on 9 April 2009

Characterization and mutagenesis of Gal/GlcNAc-6-O-sulfotransferases.

scientific article

Chemical Glycoproteomics

scientific article published on 18 November 2016

Chemical Lectinology: Tools for Probing the Ligands and Dynamics of Mammalian Lectins In Vivo

scientific article

Chemical Modulation of Protein O-GlcNAcylation via OGT Inhibition Promotes Human Neural Cell Differentiation.

scientific article published on 25 May 2017

Chemical Tools for Inhibiting Glycosylation

scientific article published on 20 March 2010

Chemical Tools for Inhibiting Glycosylation

Chemical and Enzymatic Synthesis of Glycans and Glycoconjugates

scientific article published on 20 March 2010

Chemical and biological strategies for engineering cell surface glycosylation

scientific article

Chemical approaches to glycobiology and emerging carbohydrate-based therapeutic agents

scientific article

Chemical approaches to perturb, profile, and perceive glycans

scientific article published on June 2009

Chemical approaches to the investigation of cellular systems

scientific article

Chemical remodelling of cell surfaces in living animals

scientific article

Chemical synthesis of lymphotactin: a glycosylated chemokine with a C-terminal mucin-like domain

scientific article published in March 2001

Chemical technologies for probing glycans

scientific article published on September 2006

Chemically tunable mucin chimeras assembled on living cells

scientific article published on 29 September 2015

Chemistry Is Central to Repairing Genes and Global Health: Reflections on the 2015 Nobel Prizes in Chemistry and Physiology or Medicine

scientific article published on October 2015

Chemistry in living systems

scientific article

Chemoenzymatic Fc glycosylation via engineered aldehyde tags.

scientific article published on 7 April 2014

Chemoselective approaches to glycoprotein assembly

scientific article

Chemoselective elaboration of O-linked glycopeptide mimetics by alkylation of 3-thioGalNAc

scientific article published in February 2001

Chemoselective ligation applied to the synthesis of a biantennary N-linked glycoform of CD52.

scientific article published in May 2003

Chemoselective ligation reactions with proteins, oligosaccharides and cells

scientific article

Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations

scientific journal article

Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation

scientific article published on 23 January 2017

Click-EM for imaging metabolically tagged nonprotein biomolecules

scientific article (publication date: June 2016)

Compositional profiling of heparin/heparan sulfate using mass spectrometry: assay for specificity of a novel extracellular human endosulfatase

scientific article

Computation-Guided Rational Design of a Peptide Motif That Reacts with Cyanobenzothiazoles via Internal Cysteine-Lysine Relay

scientific article published on 30 May 2018

Conditional glycosylation in eukaryotic cells using a biocompatible chemical inducer of dimerization.

scientific article published on 13 September 2008

Conformational transitions at an S-layer growing boundary resolved by cryo-TEM.

scientific article published on 5 April 2013

Confronting Racism in Chemistry Journals

scientific article published on 19 June 2020

Confronting Racism in Chemistry Journals

Conjugation of DNA to Silanized Colloidal Semiconductor Nanocrystalline Quantum Dots

Constructing azide-labeled cell surfaces using polysaccharide biosynthetic pathways

scientific article published on January 2003

Control of the molecular orientation of membrane-anchored biomimetic glycopolymers

scientific article published on July 2009

Copper-free click chemistry for dynamic in vivo imaging

scientific article

Copper-free click chemistry for the in situ crosslinking of photodegradable star polymers.

scientific article published on 24 April 2008

Copper-free click chemistry in living animals

scientific article

Corneal surface glycosylation is modulated by IL-1R and Pseudomonas aeruginosa challenge but is insufficient for inhibiting bacterial binding.

scientific article published on 21 February 2017

Cracking the carbohydrate code for selectin recognition ⬇️

scientific article published on November 1, 1995

Crosslinking studies of protein-protein interactions in nonribosomal peptide biosynthesis

scientific article

Cu-free click cycloaddition reactions in chemical biology

scientific article

Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling

scientific article published on 01 October 2018

DNA origami protection and molecular interfacing through engineered sequence-defined peptoids

scientific article published on 12 March 2020

DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis

scientific article published on 26 February 2020

DNA-barcode directed capture and electrochemical metabolic analysis of single mammalian cells on a microelectrode array

scientific article

DNA-coated AFM cantilevers for the investigation of cell adhesion and the patterning of live cells

scientific article

Deconvoluting the functions of polypeptide N-alpha-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling

scientific article

Density variant glycan microarray for evaluating cross-linking of mucin-like glycoconjugates by lectins

scientific article

Design strategies for bioorthogonal smart probes

scientific article

Design, Synthesis, Action! Molecular Machines Take the 2016 Nobel Prize in Chemistry

scientific article published on 13 October 2016

Development of IsoTaG, a Chemical Glycoproteomics Technique for Profiling Intact N- and O-Glycopeptides from Whole Cell Proteomes.

scientific article published on 28 February 2017

Differential effects of unnatural sialic acids on the polysialylation of the neural cell adhesion molecule and neuronal behavior

scientific article published on 10 January 2002

Difluorobenzocyclooctyne: Synthesis, Reactivity, and Stabilization by β-Cyclodextrin ⬇️

scientific article published on August 25, 2010

Direct cell surface modification with DNA for the capture of primary cells and the investigation of myotube formation on defined patterns

scientific article

Direct observation of kinetic traps associated with structural transformations leading to multiple pathways of S-layer assembly

scientific article

Directing flux in glycan biosynthetic pathways with a small molecule switch

scientific article published in October 2004

Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions

scholarly article by Ryan A Flynn published in April 2021

Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library We thank Sharon Long and Dave Keating for providing both the NodH sulfotransferase and APS Kinase during our preliminary experiments and Jack Kirsch for [...]

scientific article published in April 2000

Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids

scientific article published on 26 June 2006

Discovery of estrogen sulfotransferase inhibitors from a purine library screen

scientific article

Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach

scientific article

Drug targeting Mycobacterium tuberculosis cell wall synthesis: development of a microtiter plate-based screen for UDP-galactopyranose mutase and identification of an inhibitor from a uridine-based library

scientific article

Elastomeric high-mineral content hydrogel-hydroxyapatite composites for orthopedic applications.

scientific article published on June 2009

Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis

scientific article published on 30 October 2020

Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras

scientific article published on 19 October 2023

Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis ⬇️

scientific article

Engineered cell surfaces: fertile ground for molecular landscaping

scientific article published on June 1997

Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs

scientific article published on 15 May 2019

Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs

scientific article published on 16 August 2019

Engineering novel cell surface receptors for virus-mediated gene transfer

scientific article published on July 1999

Enhanced Bactericidal Effects of Pyrazinamide Toward Mycobacterium smegmatis and Mycobacterium tuberculosis upon Conjugation to a {Au(I)-triphenylphosphine}+ Moiety

scientific article published on 18 March 2020

Exercise Your Brain

scientific article published on July 2016

Expanding the diversity of unnatural cell-surface sialic acids

scientific article published in March 2004

Extensive determination of glycan heterogeneity reveals an unusual abundance of high mannose glycans in enriched plasma membranes of human embryonic stem cells

scientific article published on 6 December 2011

Fluorogenic azidofluoresceins for biological imaging

scientific article published on 10 October 2012

Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition

scientific article

Formation of 1,1-alpha,alpha-glycosidic bonds by intramolecular aglycone delivery. A convergent synthesis of trehalose

scientific article published on 01 September 2003

Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.

scientific article

Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O2 activation

scientific article published on 01 March 2019

From mechanism to mouse: a tale of two bioorthogonal reactions

scientific article

Function and Structure of a Prokaryotic Formylglycine-generating Enzyme

scientific article

Functional glass slides for in vitro evaluation of interactions between osteosarcoma TE85 cells and mineral-binding ligands

scientific article published in 2004

Functional self-assembling bolaamphiphilic polydiacetylenes as colorimetric sensor scaffolds

scientific article published in July 2004

Genome-wide, bidirectional CRISPR screens identify mucins as critical host factors modulating SARS-CoV-2 infection

scientific article

GlcNAc 2-epimerase can serve a catabolic role in sialic acid metabolism

scientific article (publication date: 7 March 2003)

Global gene expression of cells attached to a tissue engineering scaffold.

scientific article published on November 2004

Glycans in Biotechnology and the Pharmaceutical Industry

scientific article published on 20 March 2010

Glycans in cancer and inflammation--potential for therapeutics and diagnostics

scientific article

Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction

scientific article published on 25 July 2016

Glycocalyx Engineering with a Recycling Glycopolymer that Increases Cell Survival In Vivo

scientific article published on 13 November 2015

Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion

scientific article

Glycomics

scientific article published on 20 March 2010

Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc T10), involved in mucin-type O-glycosylation, has a unique GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in ppGalNAc T1 or T2

scientific article

Glycotherapy: new advances inspire a reemergence of glycans in medicine

scientific article

Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis

scientific article

Grand Challenges in Chemistry for 2016 and Beyond

scientific article published on January 2016

Happy Birthday ACS Central Science!

scientific article published on March 2016

Hierarchical assembly of model cell surfaces: synthesis of mucin mimetic polymers and their display on supported bilayers

scientific article published on 11 April 2007

Homogeneous glycopeptides and glycoproteins for biological investigation.

scientific article

Host actin polymerization tunes the cell division cycle of an intracellular pathogen.

scientific article

How many human proteoforms are there?

scientific article published in February 2018

IL-1R and MyD88 Contribute to the Absence of a Bacterial Microbiome on the Healthy Murine Cornea.

scientific article published on 29 May 2018

Identification of an N-acetylglucosamine-6-0-sulfotransferase activity specific to lymphoid tissue: an enzyme with a possible role in lymphocyte homing

scientific article

Identification of glycoproteins targeted by Trypanosoma cruzi trans-sialidase, a virulence factor that disturbs lymphocyte glycosylation

scientific article

Identification of new components of the RipC-FtsEX cell separation pathway of Corynebacterineae

scientific article published on 22 August 2019

Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogue

scientific journal article

Identification of the sulfated monosaccharides of GlyCAM-1, an endothelial-derived ligand for L-selectin

scientific article published in April 1994

Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis

scientific journal article

Illumination of growth, division and secretion by metabolic labeling of the bacterial cell surface

scientific article published on 23 January 2015

Imaging Mycobacterial Trehalose Glycolipids

scientific article published on 21 November 2017

Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes

scientific article published on 31 March 2014

Imaging beyond the proteome ⬇️

scientific article published on July 17, 2012

Imaging cell surface glycans with bioorthogonal chemical reporters

scientific article

Imaging the glycome

scholarly article

Imaging the glycosylation state of cell surface glycoproteins by two-photon fluorescence lifetime imaging microscopy.

scientific article published on 20 November 2013

Imaging the sialome during zebrafish development with copper-free click chemistry

scientific article

Immunoglobulin E sialylation regulates allergic responses

scientific article published on 07 July 2020

In vivo chemistry

scientific article published on 21 October 2013

In vivo imaging of Caenorhabditis elegans glycans

scientific article

In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter

scientific article published on 29 November 2010

In vivo imaging of membrane-associated glycans in developing zebrafish

scientific article

Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation

scientific article

Increasing intracellular trehalose is sufficient to confer desiccation tolerance to Saccharomyces cerevisiae

scientific article published on 27 April 2015

Ingredients for a Positive Safety Culture

scientific article published on November 2016

Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity

scientific article published on 25 October 2017

Inhibition of NGLY1 inactivates the transcription factor Nrf1 and potentiates proteasome inhibitor cytotoxicity

Integrated microfluidic bioprocessor for single-cell gene expression analysis

scholarly article

Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis

scientific article

Interfacing carbon nanotubes with living cells

scientific article published in May 2006

Introducing "In Focus", Community Resources Accelerating Science

scientific article published on 13 April 2020

Introducing genetically encoded aldehydes into proteins

scientific article

Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action

scientific article published on 23 October 2019

Investigating cell surface galectin-mediated cross-linking on glycoengineered cells

scientific article

Investigating cellular metabolism of synthetic azidosugars with the Staudinger ligation

scientific article published in December 2002

Investigation of the iron-sulfur cluster in Mycobacterium tuberculosis APS reductase: implications for substrate binding and catalysis

scientific journal article

Is the Nobel Prize in Chemistry Having a Boston Red Sox Moment?

Isotope Targeted Glycoproteomics (IsoTaG) to Characterize Intact, Metabolically Labeled Glycopeptides from Complex Proteomes

scientific article published on 16 March 2016

Isotope-targeted glycoproteomics (IsoTaG) analysis of sialylated N- and O-glycopeptides on an Orbitrap Fusion Tribrid using azido and alkynyl sugars

scientific article published on 30 September 2016

Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis.

scientific article

Isotopic signature transfer and mass pattern prediction (IsoStamp): an enabling technique for chemically-directed proteomics

scientific article published on 16 June 2011

Isotype-specific agglutination-PCR (ISAP): A sensitive and multiplex method for measuring allergen-specific IgE.

scientific article published on 14 December 2017

It's about the Students

scientific article published on September 2015

Ketone isosteres of 2-N-acetamidosugars as substrates for metabolic cell surface engineering

scientific article published in February 2001

Kinetic analysis of NodST sulfotransferase using an electrospray ionization mass spectrometry assay

scientific article published in November 2002

Kinetic measurements and mechanism determination of Stf0 sulfotransferase using mass spectrometry

scientific journal article

Kinetic parameters for small-molecule drug delivery by covalent cell surface targeting ⬇️

scientific article published on December 5, 2001

L-selectin-carbohydrate interactions: relevant modifications of the Lewis x trisaccharide

scientific article

LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation

scientific article published on 25 March 2021

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

scientific article published on 20 January 2020

Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling.

scholarly article

Live-Cell Labeling of Specific Protein Glycoforms by Proximity-Enhanced Bioorthogonal Ligation

scientific article published on 17 August 2015

Live-cell imaging of cellular proteins by a strain-promoted azide-alkyne cycloaddition

scientific article published on October 2010

Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins

Lysosome-targeting chimaeras for degradation of extracellular proteins

scientific article published on 29 July 2020

Mapping and quantification of over 2,000 O-linked glycopeptides in activated human T cells with isotope-targeted glycoproteomics (IsoTaG).

scientific article published on 19 January 2018

Mapping yeast N-glycosites with isotopically recoded glycans

scientific article

Mechanistic investigation of the staudinger ligation

scientific article (publication date: 2 March 2005)

Membrane curvature regulates the spatial distribution of bulky glycoproteins

scientific article published on 02 June 2022

Membrane proteomics of phagosomes suggests a connection to autophagy

scholarly article

Membrane-tethered mucin-like polypeptides sterically inhibit binding and slow fusion kinetics of influenza A virus

scientific article published on 26 May 2020

Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway

scientific article

Metabolic delivery of ketone groups to sialic acid residues. Application To cell surface glycoform engineering

scientific article

Metabolic functionalization of recombinant glycoproteins

scientific article published on September 2004

Metabolic incorporation of unnatural sialic acids into Haemophilus ducreyi lipooligosaccharides

scientific article

Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners.

scientific article published on 12 March 2012

Metabolic labeling of fucosylated glycans in developing zebrafish

scientific article

Metabolic labeling of glycans with azido sugars and subsequent glycan-profiling and visualization via Staudinger ligation

scientific article published in January 2007

Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics.

scientific article published in January 2006

Metabolic labeling of glycoproteins with chemical tags through unnatural sialic acid biosynthesis

scientific article

Metabolic labeling of sialic acids in living animals with alkynyl sugars

scientific article

Metabolic oligosaccharide engineering as a tool for glycobiology ⬇️

scientific article published on October 1, 2003

Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation

scientific article published on 28 September 2020

Metabolic selection of glycosylation defects in human cells

scientific article

Mineralization of synthetic polymer scaffolds: a bottom-up approach for the development of artificial bone

scientific article

Minimal sulfated carbohydrates for recognition by L-selectin and the MECA-79 antibody

scientific article published on October 2000

Miraculous Chemistry on the Han River

scientific article published on May 2017

MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence

scientific journal article

Modular assembly of glycoproteins: towards the synthesis of GlyCAM-1 by using expressed protein ligation

scientific article published on 01 March 2004

Modulation of ocular surface glycocalyx barrier function by a galectin-3 N-terminal deletion mutant and membrane-anchored synthetic glycopolymers

scientific article (publication date: 2013)

Molecular basis for G protein control of the prokaryotic ATP sulfurylase

scientific article published in January 2006

Molecular orientation of membrane-anchored mucin glycoprotein mimics

scientific article

Mucin granule intraluminal organization in living mucous/goblet cells. Roles of protein post-translational modifications and secretion

scientific article published on 23 December 2005

Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics

scientific article published on 30 May 2018

Mycobacterial lipid logic

scientific article

Mycobacterium tuberculosis Rv3406 is a type II alkyl sulfatase capable of sulfate scavenging

scientific article

N-carboxyanhydride polymerization of glycopolypeptides that activate antigen presenting cells through Dectin-1 and -2.

scientific article published on 25 January 2018

New aldehyde tag sequences identified by screening formylglycine generating enzymes in vitro and in vivo

scientific article

Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes

scientific article

Noncovalent complexes of APS reductase from M. tuberculosis: delineating a mechanistic model using ESI-FTICR MS.

scientific article published on 4 October 2006

Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis

scientific article published on 05 August 2016

O-Pair Search with MetaMorpheus for O-glycopeptide characterization

scientific article published on 26 October 2020

On Being a Closer

scientific article published on August 2015

On the Move

scientific article published on July 2015

Optimal Dissociation Methods Differ for N- and O-glycopeptides

scientific article published on 05 June 2020

Organelle membrane proteomics reveals differential influence of mycobacterial lipoglycans on macrophage phagosome maturation and autophagosome accumulation

scientific article

Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase.

scientific article published on 05 December 2013

PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1

scientific journal article

PapA3 is an acyltransferase required for polyacyltrehalose biosynthesis in Mycobacterium tuberculosis

scientific journal article

Physical Principles of Membrane Shape Regulation by the Glycocalyx

scientific article published on 02 May 2019

Physiological blood-brain transport is impaired with age by a shift in transcytosis

scientific article published on 01 July 2020

Piperidine-based glycodendrons as protein N-glycan prosthetics

scientific article published on 25 May 2016

Polysialic acid governs T-cell development by regulating progenitor access to the thymus

scientific article published on 08 July 2009

Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses

scientific article

Postdoc Labor Love

scientific article published on June 2016

Precision glycocalyx editing as a strategy for cancer immunotherapy.

scientific article published on 22 August 2016

Probing glycosyltransferase activities with the Staudinger ligation

scientific article

Probing mucin-type O-linked glycosylation in living animals

scholarly article

Probing the mycobacterial trehalome with bioorthogonal chemistry

scientific article

Profile of Carolyn Bertozzi. Interview by Tinsley Davis

scientific article

Programmable cell adhesion encoded by DNA hybridization

scientific article published on January 2006

Programmed assembly of 3-dimensional microtissues with defined cellular connectivity

scholarly article

Progress and Challenges for the Bottom-Up Synthesis of Carbon Nanotubes with Discrete Chirality

scientific article

Protein glycoengineering enabled by the versatile synthesis of aminooxy glycans and the genetically encoded aldehyde tag

scientific article

Proteomic dataset for altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells

scientific article

Protocol for cell type-specific labeling, enrichment, and proteomic profiling of plasma proteins in mice

scientific article published on 11 December 2021

Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx

scientific article published on 27 November 2018

Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx

scientific article published on 16 May 2019

Quantitative proteomic profiling of host-pathogen interactions: the macrophage response to Mycobacterium tuberculosis lipids

scientific article published on January 2009

Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones

scientific article

Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry

scientific article

Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe

scientific article

Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog

scientific article

Reactivity of biarylazacyclooctynones in copper-free click chemistry

scientific article

Real-time bioluminescence imaging of glycans on live cells.

scientific article

Real-time noninvasive imaging of fatty acid uptake in vivo

scientific article published on 6 September 2012

Recent advances in the chemical synthesis of mucin-like glycoproteins

scientific article

Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes.

scientific article

Regulating cell surface glycosylation by small molecule control of enzyme localization

scientific article published on December 2003

Revealing the human mucinome

scientific article published on 01 January 2022

Rv2131c from Mycobacterium tuberculosis is a CysQ 3'-phosphoadenosine-5'-phosphatase

scientific journal article

Second-generation difluorinated cyclooctynes for copper-free click chemistry.

scientific article published on 05 August 2008

Selective enrichment of azide-containing peptides from complex mixtures

scientific article published on July 2009

Self-assembled cellular microarrays patterned using DNA barcodes

scientific article published on 19 September 2007

Self-assembly of "S-bilayers", a step toward expanding the dimensionality of S-layer assemblies

scientific article published on 3 June 2013

Self-catalyzed growth of S layers via an amorphous-to-crystalline transition limited by folding kinetics

scientific article

Sensitive detection of multiple islet autoantibodies in type 1 diabetes using small sample volumes by agglutination-PCR

scientific article published on 13 November 2020

Sensitivity Optimisation of Tuberculosis Bioaerosol Sampling

scientific article published on 08 May 2020

Sensitivity optimisation of tuberculosis bioaerosol sampling

scientific article published on 03 September 2020

Sequential assembly of the septal cell envelope prior to V snapping in Corynebacterium glutamicum

scientific article published on 21 January 2019

Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology

scientific article

Single-cell-based sensors and synchrotron FTIR spectroscopy: a hybrid system towards bacterial detection

scientific article

Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug development

scientific article

Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag

scholarly article

Site-specific chemical protein conjugation using genetically encoded aldehyde tags

scientific article

Site-specific incorporation of quadricyclane into a protein and photocleavage of the quadricyclane ligation adduct

scientific article published on 04 April 2018

Small RNAs are modified with N-glycans and displayed on the surface of living cells

scientific article published on 17 May 2021

Small molecule inhibitors of mucin-type O-linked glycosylation from a uridine-based library

scientific article

Spreading of a mycobacterial cell surface lipid into host epithelial membranes promotes infectivity

scientific article published on 23 November 2020

Stereoselective Synthesis ofmyo-Inositol via Ring-Closing Metathesis:  A Building Block for Glycosylphosphatidylinositol (GPI) Anchor Synthesis

scientific article published on 01 April 2002

Straight talk with... Carolyn Bertozzi. Interview by Roxanne Palmer

scientific article published in July 2010

Strategy for dual-analyte luciferin imaging: in vivo bioluminescence detection of hydrogen peroxide and caspase activity in a murine model of acute inflammation

scientific article published on 25 January 2013

Structural Basis of Glycan Diversity

scientific article published on 20 March 2010

Structural characterization of a novel sulfated menaquinone produced by stf3 from Mycobacterium tuberculosis

scientific article published in October 2008

Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences

scientific article published on 09 April 2022

Subcellular Partitioning and Intramacrophage Selectivity of Antimicrobial Compounds against Mycobacterium tuberculosis

scientific article published on 4 January 2017

Subpolar addition of new cell wall is directed by DivIVA in mycobacteria

scientific article

Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase.

scientific article published on September 2006

Substrate specificity of the sialic acid biosynthetic pathway

scientific article published in October 2001

Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains.

scientific article published on 22 July 2013

Sulfate metabolism in mycobacteria

scientific article published on October 2006

Sulfated disaccharide inhibitors of L-selectin: deriving structural leads from a physiological selectin ligand

scientific article

Sulfation of N-acetylglucosamine by chondroitin 6-sulfotransferase 2 (GST-5).

scientific article

Sulfolipid-1 biosynthesis restricts Mycobacterium tuberculosis growth in human macrophages

scientific article

Sulfotransferases and sulfatases in mycobacteria

scientific article

Sulfotransferases as targets for therapeutic intervention.

scientific article published in September 2000

Surface molecular recognition ⬇️

scientific article published on October 30, 2001

Symbol Nomenclature for Graphical Representations of Glycans

scientific article

Symbol nomenclature for glycan representation

scientific article

Syntheses of 6-sulfo sialyl Lewis X glycans corresponding to the L-selectin ligand "sulfoadhesin"

scientific article published on 01 July 2004

Synthesis and microcontact printing of dual end-functionalized mucin-like glycopolymers for microarray applications

scientific article published on January 2009

Synthesis and reactivity of dibenzoselenacycloheptynes

scientific article published on 04 June 2013

Synthesis of Oxime-Linked Mucin Mimics Containing the Tumor-Related TN and Sialyl TN Antigens ⬇️

scientific article published on November 15, 2001

Synthesis of a bisubstrate analogue targeting estrogen sulfotransferase

scientific article published in January 2003

Synthesis of a fluorogenic cyclooctyne activated by Cu-free click chemistry

scientific article

Synthesis of glycopolymers for microarray applications via ligation of reducing sugars to a poly(acryloyl hydrazide) scaffold

scientific article

Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag

scientific article

Synthesis of lipidated green fluorescent protein and its incorporation in supported lipid bilayers.

scientific article published in October 2005

Synthesis of mono- and dideoxygenated alpha,alpha-trehalose analogs

scientific article

Synthesis of thioether-linked analogues of the 2,3-sialyl-TF and MECA-79 antigens: mucin-type glycopeptides associated with cancer and inflammation

scientific article

Synthesis of β-C-Glycosides of N-Acetylglucosamine via Keck Allylation Directed by Neighboring Phthalimide Groups ⬇️

scientific article published on September 6, 1996

Synthesis, characterization, and theory of [9]-, [12]-, and [18]cycloparaphenylene: carbon nanohoop structures

scientific article published on December 2008

Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial Species

scientific article published in 2011

Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19

scientific article

Synthetic analogues of glycosylphosphatidylinositol-anchored proteins and their behavior in supported lipid bilayers

scientific article

Synthetic glycobiology: Exploits in the Golgi compartment

scientific article published on 23 October 2006

Synthetic glycopeptides and glycoproteins as tools for biology.

scientific article

Synthetic riboswitches that induce gene expression in diverse bacterial species

scientific article published on 8 October 2010

Synthetic studies toward Mycobacterium tuberculosis sulfolipid-I.

scientific article published on 04 January 2008

Synthetic trehalose glycolipids confer desiccation resistance to supported lipid monolayers

scientific article published on May 2009

Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection

scientific article published on 06 October 2020

Systemic Fluorescence Imaging of Zebrafish Glycans with Bioorthogonal Chemistry

scientific article

TMIC-43. A TENSION-MEDIATED GLYCOCALYX FEEDBACK LOOP PROMOTES A MESENCHYMAL, STEM-LIKE PHENOTYPE IN GLIOBLASTOMA

Targeted Desialylation Overcomes Glyco-Immune Checkpoints and Potentiates the Anticancer Immune Response in Vivo

Targeted glycan degradation potentiates the anticancer immune response in vivo

scientific article published on 17 August 2020

Targeted metabolic labeling of yeast N-glycans with unnatural sugars

scientific article

The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C

scientific article published on 01 December 2021

The Centrality of Chemistry

scientific article published on 23 March 2015

The Ecstasy and Agony of Assay Interference Compounds

scientific article

The Ecstasy and Agony of Assay Interference Compounds

The Ecstasy and Agony of Assay Interference Compounds

The Ecstasy and Agony of Assay Interference Compounds

The Ecstasy and Agony of Assay Interference Compounds

scientific article published on 28 February 2017

The Ecstasy and Agony of Assay Interference Compounds

The Ecstasy and Agony of Assay Interference Compounds

scientific article published in 2017

The Ecstasy and Agony of Assay Interference Compounds.

scientific article published on 28 February 2017

The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth.

scientific article

The Mycobacterium tuberculosis virulence factor trehalose dimycolate imparts desiccation resistance to model mycobacterial membranes

scientific article published on 7 March 2008

The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation

scientific article

The Regulation of Sulfur Metabolism in Mycobacterium tuberculosis ⬇️

scientific article published on July 21, 2011

The cancer glycocalyx mechanically primes integrin-mediated growth and survival

scientific article

The chemistry and biology of mucin-type O-linked glycosylation

scientific article

The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans

scientific article

The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins

scientific article

The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins

scientific article published on 25 March 2019

The roles of enzyme localisation and complex formation in glycan assembly within the Golgi apparatus

scientific article published in August 2004

The rv1184c locus encodes Chp2, an acyltransferase in Mycobacterium tuberculosis polyacyltrehalose lipid biosynthesis

scientific article

The selectins and their ligands

scientific article published on October 1994

The stem region of the sulfotransferase GlcNAc6ST-1 is a determinant of substrate specificity

scientific article

Thiacycloalkynes for copper-free click chemistry

scientific article published on 26 January 2012

Toward Point-of-Care Detection of Mycobacterium tuberculosis: A Brighter Solvatochromic Probe Detects Mycobacteria within Minutes

scientific article

Training the next generation of biomedical investigators in glycosciences

scientific article published on February 2016

Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement

scientific article published in January 2018

Trehalose is required for growth of Mycobacterium smegmatis

scientific article published on 21 April 2004

Two selectins converge on sulphate. Leukocyte adhesion

scientific article published on March 1996

Tyrosylprotein sulfotransferase inhibitors generated by combinatorial target-guided ligand assembly

scientific article published in February 2002

Ultrasensitive Antibody Detection by Agglutination-PCR (ADAP)

scientific article

Update to Our Reader, Reviewer, and Author Communities-April 2020

scientific article published on 22 April 2020

Update to Our Reader, Reviewer, and Author Communities-April 2020

scientific article published on 23 April 2020

Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC.

scientific article published in April 2009

Using phage display to select antibodies recognizing post-translational modifications independently of sequence context

scientific article published on 12 September 2006

Vaccine efficacy of an attenuated but persistent Mycobacterium tuberculosis cysH mutant.

scientific article published in April 2007

Visualization of mycobacterial membrane dynamics in live cells

scientific article published on 11 January 2017

Visualizing enveloping layer glycans during zebrafish early embryogenesis

scientific article

Voices of biotech

scientific article published on March 2016

Werner Reutter: A Visionary Pioneer in Molecular Glycobiology.

scientific article published on 16 June 2017

Xylosyltransferase II is the predominant isoenzyme which is responsible for the steady-state level of xylosyltransferase activity in human serum.

scientific article

Zika Virus Infection Prevents Host mRNA Nuclear Export by Disrupting UPF1 Function

scientific article

cDNA cloning and expression of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase T1 from Toxoplasma gondii

scientific article published in October 2003

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