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List of works by Sean J. Morrison

27-Hydroxycholesterol induces hematopoietic stem cell mobilization and extramedullary hematopoiesis during pregnancy.

scientific article published on 7 August 2017

A genetic determinant that specifically regulates the frequency of hematopoietic stem cells

scientific article published in January 2002

A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis

scientific article

A meta-analysis of the efficacy of allopurinol in reducing the incidence of myocardial infarction following coronary artery bypass grafting.

scientific article published on 11 July 2018

A metabolic map of hematopoietic stem cells.

scientific article published on 28 May 2014

A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties

scientific article

A perisinusoidal niche for extramedullary haematopoiesis in the spleen

scientific article published on 16 November 2015

Adult haematopoietic stem cell niches

scientific article

Advancing Stem Cell Science and Translation

scientific article published on June 2016

Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems

scientific journal article

An in vivo model to study and manipulate the hematopoietic stem cell niche

scientific article

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

scientific article published on 21 August 2017

Asymmetric and symmetric stem-cell divisions in development and cancer

scientific article

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

scientific article

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

scientific article (publication date: 15 May 2003)

Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo

scientific article

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

scientific article

Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism

scientific article

Bmi1, stem cells, and senescence regulation

scientific article

Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF.

scientific article

Brain repair by endogenous progenitors

scientific article

CD144 (VE-cadherin) is transiently expressed by fetal liver hematopoietic stem cells

scientific article published on 14 April 2005

CD150- cells are transiently reconstituting multipotent progenitors with little or no stem cell activity

scientific article published in April 2008

CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo.

scientific article published on 21 July 2017

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance

scientific article

Cancer stem cells

scientific article published on 01 March 2005

Cancer stem cells: impact, heterogeneity, and uncertainty

scientific article published in March 2012

Cancer, Oxidative Stress, and Metastasis

scientific article published on 12 January 2017

Cell size is a determinant of stem cell potential during aging

scientific article published on 12 November 2021

Cell-intrinsic differences between stem cells from different regions of the peripheral nervous system regulate the generation of neural diversity

scientific article published in August 2002

Cellular differences in protein synthesis regulate tissue homeostasis

scientific article

Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton

scientific article published on 13 December 2016

Connecting the Interstellar Gas and Dust Properties in Distant Galaxies Using Quasar Absorption Systems

Crossing the boundaries of sensory neurogenesis

Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells.

scientific article published in October 2000

DHODH modulates transcriptional elongation in the neural crest and melanoma

scientific article

Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal

scientific article

Demonstration that Thy(lo) subsets of mouse bone marrow that express high levels of lineage markers are not significant hematopoietic progenitors

scientific article published on 01 June 1994

Developmental changes in Notch1 and numb expression mediated by local cell-cell interactions underlie progressively increasing delta sensitivity in neural crest stem cells

scientific article published in April 2002

Digoxin Plus Trametinib Therapy Achieves Disease Control in BRAF Wild-Type Metastatic Melanoma Patients

scientific article published on 06 March 2017

Distinct Brca1 Mutations Differentially Reduce Hematopoietic Stem Cell Function

scientific article published on January 2017

Diverse mechanisms regulate stem cell self-renewal

scientific article

Efficient tumour formation by single human melanoma cells

scientific article

Endothelial and perivascular cells maintain haematopoietic stem cells

scientific article published on 25 January 2012

Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors

scientific article published on 28 March 2006

Enteric glia are multipotent in culture but primarily form glia in the adult rodent gut.

scientific article

Erratum to "Ultrasound-guided nerve blocks for intracapsular and extracapsular hip fractures" [Am J Emerg Med 34(3) (2016), 586-589]

scientific article published on 25 May 2016

Erratum: Corrigendum: Lens regeneration using endogenous stem cells with gain of visual function

scientific article published in Nature

Erratum: Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

scientific article published in Nature

Erratum: Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma

scientific article published on 29 September 2016

Evaluation of Xie et al.: Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal

scientific article published on 01 November 2019

FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

scientific article published on 17 August 2010

From stem cells to lymphocytes: biology and transplantation

scientific article published on June 1997

Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes

scientific article (publication date: 30 October 2003)

Glucosylceramide and Glucosylsphingosine Quantitation by Liquid Chromatography-Tandem Mass Spectrometry to Enable In Vivo Preclinical Studies of Neuronopathic Gaucher Disease

scientific article

HIV-1 utilizes the CXCR4 chemokine receptor to infect multipotent hematopoietic stem and progenitor cells

scientific article

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

scientific article published on 24 February 2013

Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU.

scientific article published on 29 August 2007

Haematopoietic stem cells require a highly regulated protein synthesis rate

scientific article

Hematopoietic stem and progenitor cells regulate the regeneration of their niche by secreting Angiopoietin-1

scientific article published on 30 March 2015

Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes.

scientific article published on January 1998

Hematopoietic stem cells do not depend on N-cadherin to regulate their maintenance

scientific article published in February 2009

Hematopoietic stem cells: challenges to expectations

scientific article published on April 1997

Heterogeneity in cancer: cancer stem cells versus clonal evolution

scientific article (publication date: 4 September 2009)

Heterogeneity of hematopoietic stem cells: implications for clinical applications.

scientific article published on July 1995

Hirschsprung disease is linked to defects in neural crest stem cell function

scientific article published in August 2003

Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression

scientific article

Human and rhesus macaque hematopoietic stem cells cannot be purified based only on SLAM family markers

scientific article published on 16 December 2010

Human melanoma metastasis in NSG mice correlates with clinical outcome in patients

scientific article published in November 2012

Huntingtin Interacting Protein 1 mutations lead to abnormal hematopoiesis, spinal defects and cataracts

scientific article published on 3 March 2004

Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target

scientific article published on 01 October 2020

Identification of a lineage of multipotent hematopoietic progenitors.

scientific article

Identification of hair shaft progenitors that create a niche for hair pigmentation

scientific article

Identifying metabolomic features that predict metastasis of melanoma from a primary site

In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells

scientific article

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

scientific article (publication date: 28 September 2006)

Infection mobilizes hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signaling

scientific article

Inhibition of AMPK catabolic action by GSK3.

scientific article published on 25 April 2013

Integrating physiological regulation with stem cell and tissue homeostasis

scientific article published in May 2011

Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass

Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass

scientific article published on 11 January 2019

Intrinsic differences among spatially distinct neural crest stem cells in terms of migratory properties, fate determination, and ability to colonize the enteric nervous system

scientific article published on 24 October 2006

Lack of Population Diversity in Commonly Used Human Embryonic Stem-Cell Lines

scientific article published on 16 December 2009

Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance.

scientific article

Lens regeneration using endogenous stem cells with gain of visual function

scientific article

Leptin Receptor Promotes Adipogenesis and Reduces Osteogenesis by Regulating Mesenchymal Stromal Cells in Adult Bone Marrow.

scientific article published on 24 March 2016

Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow

scientific article

Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system

scientific journal article

Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution

scientific article published on 31 October 2019

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

scientific article

Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation

scientific article published on 12 June 2019

Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice.

scientific article

Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells

scientific article published in 2022

Lymph protects metastasizing melanoma cells from ferroptosis

scientific article published on 19 August 2020

Maintaining hematopoietic stem cells in the vascular niche

scientific article published on December 2006

Mechanisms of stem cell self-renewal

scientific article published on January 2009

Mechanisms that regulate stem cell aging and life span

scientific article published on February 2013

Metabolic Adaptation Fuels Lymph Node Metastasis

scientific article published on 01 April 2019

Metabolic heterogeneity confers differences in melanoma metastatic potential

scientific article published on 18 December 2019

Metabolic mechanisms regulating distinct steps of the melanoma metastatic cascade

Metabolic regulation of stem cell function.

scientific article

Neural crest stem cells persist in the adult gut but undergo changes in self-renewal, neuronal subtype potential, and factor responsiveness

scientific article

Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells

scientific article published on 20 October 2004

Neuronal differentiation: proneural genes inhibit gliogenesis.

scientific article

Niche-breadth of freshwater macrophytes occurring in tropical southern African rivers predicts species global latitudinal range

Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy

scientific article

Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness

scientific article

Oxidative stress inhibits distant metastasis by human melanoma cells

scientific article

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

scientific article published in 2022

Persistence of leukemia-initiating cells in a conditional knockin model of an imatinib-responsive myeloproliferative disorder

scientific article published on August 2009

Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized

scientific article

Physiological Notch signaling promotes gliogenesis in the developing peripheral and central nervous systems

scientific article published on 30 May 2007

Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells

scientific article published on 11 July 2017

Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress

scientific article

Precise let-7 expression levels balance organ regeneration against tumor suppression

scientific article

Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain

scientific article

Prospective identification of tumorigenic breast cancer cells

scientific article

Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells

scientific article published on March 1999

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

scientific article (publication date: 25 May 2006)

Pten-uating neural growth

scientific article published on 01 January 2002

Regulatory mechanisms in stem cell biology

scientific article published on February 1997

Reply

article published in 2004

Restricted Hematopoietic Progenitors and Erythropoiesis Require SCF from Leptin Receptor+ Niche Cells in the Bone Marrow

scientific article published on 17 January 2019

Retrospective study of 28 cases of cholecystoduodenostomy performed using endoscopic gastrointestinal anastomosis stapling equipment

scientific article published in January 2008

SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity

scientific article published on 11 October 2005

SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors

scientific article published on July 2013

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

scientific article (publication date: July 2005)

Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells

scientific journal article

Sox17 expression confers self-renewal potential and fetal stem cell characteristics upon adult hematopoietic progenitors

scientific article

Sox17 promotes tumor angiogenesis and destabilizes tumor vessels in mice

scientific article

Spatial differences in hematopoiesis but not in stem cells indicate a lack of regional patterning in definitive hematopoietic stem cells

scientific article published in July 2005

Stable isotope tracing to assess tumor metabolism in vivo

scientific article published in 2021

Stem cell potential: can anything make anything?

scientific article

Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors.

scientific article published on January 2005

Stem cells use distinct self-renewal programs at different ages.

scientific article published on January 2008

Stem-cell competition

scientific article published in July 2002

Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma.

scientific article published on 22 August 2016

TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

scientific article published on 12 February 2020

TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling

scientific article published on 01 August 2019

Telomerase activity in hematopoietic cells is associated with self-renewal potential

scientific article

Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression

scientific article

Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells

scientific article

Temporally distinct requirements for endothelin receptor B in the generation and migration of gut neural crest stem cells

scientific article published on December 2003

The Biology of Hematopoietic Stem Cells

scientific article published on 01 January 1995

The PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: a mechanistic difference between normal and cancer stem cells

scientific article published on 2 April 2008

The Purification of Mouse Hematopoietic Stem Cells at Sequential Stages of Maturation

scientific article published on January 1, 2002

The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts.

scientific article published in November 2017

The aging of hematopoietic stem cells

scientific article published in September 1996

The bone marrow niche for haematopoietic stem cells

scientific article published in January 2014

The last shall not be first: the ordered generation of progeny from stem cells.

scientific article

The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells

scientific article published on February 2008

The purification and characterization of fetal liver hematopoietic stem cells.

scientific article

The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs.

scientific article published on 04 August 2016

Time to do something about reproducibility

scientific article

To begin at the beginning

scientific article published in Nature

Toward an understanding of the physiological function of Mammalian stem cells

scientific article

Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells

scientific article

Tumorigenic cells are common in mouse MPNSTs but their frequency depends upon tumor genotype and assay conditions

scientific article published on February 2012

Tumour heterogeneity and cancer cell plasticity

scientific article (publication date: 19 September 2013)

Ultrasound-guided nerve blocks for intracapsular and extracapsular hip fractures

scientific article published on 14 December 2015

Uncertainty in the niches that maintain haematopoietic stem cells

scientific article published on 07 March 2008

mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion.

scientific article

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