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List of works by Scott L. Friedman

357 - Cenicriviroc Treatment for Adults with Non-Alcoholic Steatohepatitis: Year 2 Analysis of the Phase 2B Centaur Study

scholarly article published in May 2018

A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C.

scientific article

A Candidate Gene Study for the Association of Host Single Nucleotide Polymorphisms with Liver Cirrhosis Risk in Chinese Hepatitis B Patients ⬇️

scientific article published on July 11, 2013

A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells

scientific article

A Germline DNA Polymorphism Enhances Alternative Splicing of theKLF6Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

article

A Randomized, Placebo-Controlled Trial of Cenicriviroc for Treatment of Nonalcoholic Steatohepatitis with Fibrosis.

scientific article published on 17 August 2017

A genomic and clinical prognostic index for hepatitis C-related early-stage cirrhosis that predicts clinical deterioration

scientific article

A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular carcinoma after curative resection

scientific article published on 4 June 2015

A histone deacetylase inhibitor, largazole, decreases liver fibrosis and angiogenesis by inhibiting transforming growth factor-β and vascular endothelial growth factor signalling

scientific article

A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.

scientific article

A novel murine model to deplete hepatic stellate cells uncovers their role in amplifying liver damage in mice.

scientific article published on January 2013

A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma.

scientific article published on 9 April 2018

A polymorphism that delays fibrosis in hepatitis C promotes alternative splicing of AZIN1, reducing fibrogenesis

scientific article published on December 2011

Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis.

scientific article published on January 2003

Activation of Hepatic Stellate Cells Requires Dissociation of E-Cadherin-Containing Adherens Junctions with Hepatocytes

scientific article published on 17 December 2020

Acute liver failure is associated with elevated liver stiffness and hepatic stellate cell activation.

scientific article

Acyclic retinoid in the chemoprevention of hepatocellular carcinoma (review).

scientific article published on April 2004

Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats

scientific article published on 24 November 2006

Advanced quantitative phenotypic fibrosis and steatosis scoring is more superior to histology-based conventional staging in NASH animal models

scientific article published in 2022

Altered Microbiota Diversity and Bile Acid Signaling in Cirrhotic and Noncirrhotic NASH-HCC

scientific article published on 01 March 2020

Altered global microRNA expression in hepatic stellate cells LX-2 by angiotensin-(1-7) and miRNA-1914-5p identification as regulator of pro-fibrogenic elements and lipid metabolism

scientific article published on 7 March 2018

An Immune Gene Expression Signature Associated With Development of Human Hepatocellular Carcinoma Identifies Mice That Respond to Chemopreventive Agents

scientific article published on 22 July 2019

Anti-fibrotic activity and enhanced interleukin-6 production by hepatic stellate cells in response to imatinib mesylate

scientific article

Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC.

scientific article published on 8 February 2006

Antifibrotic Activity of Sorafenib in Experimental Hepatic Fibrosis: Refinement of Inhibitory Targets, Dosing, and Window of Efficacy In Vivo ⬇️

scientific article published on August 24, 2012

Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver

scientific article published on 17 February 2020

Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis

scientific article

Antifibrotic Therapies: Where Are We Now?

scientific article published on 12 February 2016

Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans

scientific article

Apoptosis: the nexus of liver injury and fibrosis.

scientific article published on February 2004

Apoptotic body engulfment by a human stellate cell line is profibrogenic.

scientific article published on May 2003

Author Correction: Senolytic CAR T cells reverse senescence-associated pathologies

scientific article published in 2024

Autophagy and mesenchymal cell fibrogenesis

scientific article

Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap

scientific article published in Nature Communications

Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.

scientific article

BMP-7 opposes TGF-beta1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2.

scientific article published on 26 August 2005

Basic science to clinical trials in non-alcoholic fatty liver disease and alcohol-related liver disease: collaboration with industry

scientific article published on 05 January 2021

Beneficial effect of glatiramer acetate (Copaxone) on immune modulation of experimental hepatic fibrosis

scientific article published on 12 October 2006

CCN1/CYR61 overexpression in hepatic stellate cells induces ER stress-related apoptosis

scientific article published on 26 October 2015

CXCL12 induces hepatic stellate cell contraction through a calcium-independent pathway

scientific article published on 27 June 2013

Carcinogen-induced hepatic tumors in KLF6+/- mice recapitulate aggressive human hepatocellular carcinoma associated with p53 pathway deregulation.

scientific article

Case definitions for inclusion and analysis of endpoints in clinical trials for nonalcoholic steatohepatitis through the lens of regulatory science.

scientific article published on 23 October 2017

Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils

scientific article

Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration Joint Workshop

scientific article published on 19 March 2015

Characterization of the human Activin-A receptor type II-like kinase 1 (ACVRL1) promoter and its regulation by Sp1

scientific article

Colors of 2625 Quasars at 0 < z < 5 Measured in the Sloan Digital Sky Survey Photometric System*

scientific article published in Astronomical Journal

Combination therapy for hepatocellular carcinoma: additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib

scientific article

Commentary: Gastroenterology and hepatology: an evolving marriage, not an imminent divorce

scientific article published on 01 January 2009

Comparison of ADAPT, FIB-4 and APRI as non-invasive predictors of liver fibrosis and NASH within the CENTAUR screening population

scientific article published in 2021

Composite Quasar Spectra from the Sloan Digital Sky Survey

scientific article published in Astronomical Journal

Contributions of metabolic dysregulation and inflammation to nonalcoholic steatohepatitis, hepatic fibrosis, and cancer

scientific article

Corrigendum to: "Impaired endothelial autophagy promotes liver fibrosis by aggravating the oxidative stress response during acute liver injury" [J Hepatol (2019) 458-469]

scientific article published on 27 June 2020

Current and Future Therapeutic Regimens for Non-alcoholic Fatty Liver Disease (NAFLD) and Non-alcoholic Steatohepatitis (NASH).

scientific article

Current status of novel antifibrotic therapies in patients with chronic liver disease ⬇️

scientific article published on November 1, 2011

Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1.

scientific article published in June 2004

Cytochrome P450 2E1-derived Reactive Oxygen Species Mediate Paracrine Stimulation of Collagen I Protein Synthesis by Hepatic Stellate Cells ⬇️

scientific article published on January 8, 2002

Dendritic Cells in Alcoholic Liver Injury and Fibrosis ⬇️

scientific article published on February 1, 2011

Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression

scientific article published on January 2012

Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6

scientific article published on 18 October 2005

Devilish Effects of Taz in Nonalcoholic Steatohepatitis

scientific article published on 27 October 2016

Diagnosis of hepatic fibrosis in patients with chronic hepatitis C.

scientific article published on November 2006

Diagnostic Modalities for Non-alcoholic Fatty Liver Disease (NAFLD), Non-alcoholic Steatohepatitis (NASH) and Associated Fibrosis.

scientific article published on 9 December 2017

Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation.

scientific article

Downregulation of hepatic stellate cell activation by retinol and palmitate mediated by adipose differentiation-related protein (ADRP).

scientific article

E3 Ubiquitin Ligase Synoviolin Is Involved in Liver Fibrogenesis ⬇️

scientific article (publication date: 25 October 2010)

Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR Phase 2b study design

scientific article

Emerging and disease-specific mechanisms of hepatic stellate cell activation

scientific article published on 14 May 2015

Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy

scientific article published on 26 February 2013

Enhanced hepatocarcinogenesis in mouse models and human hepatocellular carcinoma by coordinate KLF6 depletion and increased messenger RNA splicing ⬇️

scientific article published on August 27, 2012

Enhanced oral tolerance in transgenic mice with hepatocyte secretion of IL-10.

scientific article published in September 2005

Epithelial Xbp1 is required for cellular proliferation and differentiation during mammary gland development

scientific article

Evidence that Sp1 positively and Sp3 negatively regulate and androgen does not directly regulate functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) gene expression in normal human prostate epithelial cells

scientific article

Experimental models of hepatocellular carcinoma

scientific article

Fibrosis Regression After Eradication of Hepatitis C Virus: From Bench to Bedside

Focal gains of VEGFA and molecular classification of hepatocellular carcinoma

scientific article published on August 2008

Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis

scientific article published in April 2013

Frequent inactivation of the tumor suppressor Kruppel-like factor 6 (KLF6) in hepatocellular carcinoma

scientific article

Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma

scientific article published on September 2007

Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of Toll-like receptor 4 to hepatic stellate cell responses.

scientific article

Functional role of the KLF6 tumour suppressor gene in gastric cancer

scientific article

Functions of autophagy in normal and diseased liver

scientific article published on 22 May 2013

Future trends in hepatology: challenges and opportunities

scientific article published on 01 August 2008

Galaxy Clustering in Early Sloan Digital Sky Survey Redshift Data ⬇️

scientific article published in the Astrophysical Journal

Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

scientific article

Gene-expression signature of vascular invasion in hepatocellular carcinoma.

scientific article published on 13 April 2011

Genetic Characterization of Rat Hepatic Stellate Cell Line HSC-T6 for In Vitro Cell Line Authentication

scientific article published on 29 May 2022

Genetic characteristics of the human hepatic stellate cell line LX-2.

scientific article

Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma

scientific article published on April 2007

Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease

scientific article published on 27 June 2013

Genomics and proteomics in liver fibrosis and cirrhosis.

scientific article published on 3 January 2012

Genomics and signaling pathways in hepatocellular carcinoma.

scientific article published on February 2007

Glucokinase links Krüppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease ⬇️

scientific article published on March 1, 2012

Granulocyte macrophage colony-stimulating factor is required for aortic dissection/intramural haematoma

scientific article published on 29 April 2015

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

HBV and HCV Screening of African Urban Populations in New York City with Linkage to Care by a Patient Navigator: A New Model for Viral Hepatitis Community Outreach Presidential Poster ⬇️

scholarly article

Hepatic Autophagy Deficiency Compromises Farnesoid X Receptor Functionality and Causes Cholestatic Injury

scientific article published on 08 March 2019

Hepatic decompensation/serious adverse events in post-liver transplantation recipients on sofosbuvir for recurrent hepatitis C virus

scientific article published on March 2016

Hepatic fibrogenesis

scientific article published on 01 November 2007

Hepatic fibrosis

scientific article

Hepatic fibrosis 2006: report of the Third AASLD Single Topic Conference

scientific article published in January 2007

Hepatic fibrosis and the microenvironment: fertile soil for hepatocellular carcinoma development

scientific article published on January 2014

Hepatic fibrosis: Concept to treatment

scientific article published on April 2015

Hepatic stellate cells and liver fibrosis

scientific article

Hepatic stellate cells as key target in liver fibrosis

scientific article published on 12 May 2017

Hepatitis Outreach Network: A practical strategy for hepatitis screening with linkage to care in foreign-born communities ⬇️

scientific article published on January 15, 2013

Hepatocyte KLF6 expression affects FXR signalling and the clinical course of primary sclerosing cholangitis

scientific article published on 27 May 2020

Hepatocyte growth factor enhances alternative splicing of the Kruppel-like factor 6 (KLF6) tumor suppressor to promote growth through SRSF1.

scientific article published on 2 August 2012

High mobility group box 1 activates toll like receptor 4 signaling in hepatic stellate cells ⬇️

scientific article published on July 27, 2012

Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features

scientific article published on 14 June 2017

Identification of two gene variants associated with risk of advanced fibrosis in patients with chronic hepatitis C.

scientific article

Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes

scientific article published in September 2004

Impaired Endothelial Autophagy Promotes Liver Fibrosis By Aggravating The Oxidative Stress Response During Acute Liver Injury

scientific article published on 25 October 2018

Increased alternative splicing of the KLF6 tumour suppressor gene correlates with prognosis and tumour grade in patients with pancreatic cancer.

scientific article

Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib.

scientific article

Inhibition of the CXCL12/CXCR4 chemokine axis with AMD3100, a CXCR4 small molecule inhibitor, worsens murine hepatic injury

scientific article

Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma

scientific article published on September 2009

Integrin alpha 11 in the regulation of the myofibroblast phenotype: implications for fibrotic diseases.

scientific article published on 17 November 2017

Interleukin-15 receptor α on hepatic stellate cells regulates hepatic fibrogenesis in mice

scientific article

Interleukin-6 protects hepatocytes from CCl4-mediated necrosis and apoptosis in mice by reducing MMP-2 expression

scientific article

KLF6 allelic loss is associated with tumor recurrence and markedly decreased survival in head and neck squamous cell carcinoma.

scientific article

KLF6 degradation after apoptotic DNA damage.

scientific article published on 13 November 2006

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.

scientific article

Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer.

scientific article

Krüppel cripples prostate cancer: KLF6 progress and prospects

scientific article

Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury

scientific article published on 14 August 2017

Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1.

scientific article

Kupffer cell activation by ambient air particulate matter exposure may exacerbate non-alcoholic fatty liver disease

scientific article

L(59) TGF-β LAP degradation products serve as a promising blood biomarker for liver fibrogenesis in mice

scientific article

LAP degradation product reflects plasma kallikrein-dependent TGF-β activation in patients with hepatic fibrosis

scientific article

Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice

scientific article

Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis.

scientific article published on 30 December 2016

Liver transplant for hepatocellular carcinoma in the United States: Evolving trends over the last three decades

scientific article published on 11 October 2019

Loss of matrix metalloproteinase-2 amplifies murine toxin-induced liver fibrosis by upregulating collagen I expression

scientific article

Mannose Phosphate Isomerase and Mannose Regulate Hepatic Stellate Cell Activation and Fibrosis in Zebrafish and Humans

scientific article published on 24 May 2019

Mechanisms of NAFLD development and therapeutic strategies.

scientific article published on 2 July 2018

Mechanisms of hepatic stellate cell activation

scientific article published on 10 May 2017

MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a

scientific article published on 13 February 2011

Modeling dysbiosis of human NASH in mice: Loss of gut microbiome diversity and overgrowth of Erysipelotrichales

scientific article published on 04 January 2021

Modulation of cardiac fibrosis by Krüppel-like factor 6 through transcriptional control of thrombospondin 4 in cardiomyocytes.

scientific article

Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition

scientific article published on December 2016

Molecular diagnosis of chronic liver disease and hepatocellular carcinoma: the potential of gene expression profiling

scientific article published on November 2006

Molecular mechanism for growth suppression of human hepatocellular carcinoma cells by acyclic retinoid

scientific article

Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection

scientific article

NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity

scientific article

Nonalcoholic Steatohepatitis Is Associated With Increased Mortality in Obese Patients Undergoing Bariatric Surgery.

scientific article published on 19 October 2015

Obesity, inflammatory signaling, and hepatocellular carcinoma-an enlarging link

scientific article published in February 2010

PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis

scientific article published on 18 August 2016

Pathobiology of liver fibrosis: a translational success story

scientific article

Pathogenesis of liver fibrosis

scientific article published on January 2011

Perceptions of Hepatitis B among African Immigrants in New York City: An Opportunity to Increase Awareness and Avoid Stigma ⬇️

scholarly article

Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo

scientific article published on March 2006

Phosphorylation of retinoid X receptor suppresses its ubiquitination in human hepatocellular carcinoma

scientific article published on February 2002

Pivotal role of mTOR signaling in hepatocellular carcinoma

scientific article published on 20 August 2008

Platelets arrive at the scene of fibrosis……studies ⬇️

scientific article published on December 16, 2010

Polymorphism of ornithine decarboxylase antizyme inhibitor 1 gene is associated with liver cirrhosis in Chinese hepatitis B patients

scientific article published on March 1, 2011

Prevention of rat hepatocarcinogenesis by acyclic retinoid is accompanied by reduction in emergence of both TGF-alpha-expressing oval-like cells and activated hepatic stellate cells

scientific article published in January 2005

Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis

scientific article published on 17 January 2013

Prostaglandin E2 inhibits transforming growth factor beta 1-mediated induction of collagen alpha 1(I) in hepatic stellate cells

scientific article published on August 2004

Publisher Correction: SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis

scientific article published on 06 August 2019

Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo

scientific article

Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma.

scientific article published on 13 February 2008

Real-world cure rates for hepatitis C virus treatments that include simeprevir and/or sofosbuvir are comparable to clinical trial results

scientific article published in November 2017

Reduced hepatic stellate cell expression of Kruppel-like factor 6 tumor suppressor isoforms amplifies fibrosis during acute and chronic rodent liver injury

scientific article

Regression of fibrosis and reversal of cirrhosis in rats by galectin inhibitors in thioacetamide-induced liver disease

scientific article (publication date: 2013)

Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation.

scientific article

Regulation of hepatic stellate cell activation and growth by transcription factor myocyte enhancer factor 2

scientific article published on 01 October 2004

Resveratrol amplifies profibrogenic effects of free fatty acids on human hepatic stellate cells

scientific article

Retinoids in cancer chemoprevention

scientific article published on May 2004

Reversal of hepatic fibrosis -- fact or fantasy?

scientific article

Risk Factors for Hepatocellular Carcinoma in Cirrhotic Patients with Chronic Hepatitis B.

scientific article published on 8 July 2016

Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma

scientific article published on 9 January 2013

Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination.

scientific article

SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis.

scientific article published on 6 November 2017

SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis

scientific article published in Scientific Reports

Senolytic CAR T cells reverse senescence-associated pathologies

scientific article published on 17 June 2020

Sex steroids have differential effects on growth and gene expression in primary human prostatic epithelial cell cultures derived from the peripheral versus transition zones.

scientific article published on 25 August 2005

Shared and Tissue-Specific Expression Signatures between Bone Marrow from Primary Myelofibrosis and Essential Thrombocythemia

scientific article published on 01 November 2019

Sloan Digital Sky Survey Imaging of Low Galactic Latitude Fields: Technical Summary and Data Release

scientific article published in Astronomical Journal

Sloan Digital Sky Survey: Early Data Release

scientific article published in Astronomical Journal

Stellate cell apoptosis by a soluble mediator from immortalized human hepatocytes

scientific article published in August 2006

Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species ⬇️

scientific article published on January 1, 2002

Suppression of glioblastoma tumorigenicity by the Kruppel-like transcription factor KLF6.

scientific article

Synergistic induction of apoptosis by acyclic retinoid and interferon-beta in human hepatocellular carcinoma cells

scientific article published in November 2002

TGF-beta regulates the expression of transcription factor KLF6 and its splice variants and promotes co-operative transactivation of common target genes through a Smad3-Sp1-KLF6 interaction

scientific article

Targeted and regulable expression of transgenes in hepatic stellate cells and myofibroblasts in culture and in vivo using an adenoviral Cre/loxP system to antagonise hepatic fibrosis

scientific article published on 6 September 2006

Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread.

scientific article published in July 2005

The Fifth Data Release of the Sloan Digital Sky Survey

article

The First Data Release of the Sloan Digital Sky Survey

scientific article published in Astronomical Journal

The First Hour of Extragalactic Data of the Sloan Digital Sky Survey Spectroscopic Commissioning: The Coma Cluster

scientific article published in Astronomical Journal

The Fourth Data Release of the Sloan Digital Sky Survey

article

The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease

scientific article

The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation

scientific article published on 24 March 2016

The Luminosity Function of Galaxies in SDSS Commissioning Data

scientific article published in Astronomical Journal

The RING finger protein, RNF8, interacts with retinoid X receptor alpha and enhances its transcription-stimulating activity

scientific article (publication date: 30 April 2004)

The Second Data Release of the Sloan Digital Sky Survey

scientific article published in Astronomical Journal

The Sixth Data Release of the Sloan Digital Sky Survey

scientific article published in 2008

The Sloan Digital Sky Survey Quasar Catalog. I. Early Data Release

scientific article published in Astronomical Journal

The Sloan Digital Sky Survey: Technical Summary

scientific article published in Astronomical Journal

The Third Data Release of the Sloan Digital Sky Survey

scientific article published in Astronomical Journal

The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination

scientific article (publication date: May 2016)

The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic Activity in Hepatic Stellate Cells Through Autophagy

scientific article published on 20 December 2016

The expression patterns and clinical significance of microRNAs in liver diseases and hepatocellular carcinoma

scientific article published on January 1, 2013

The multi-object, fiber-fed spectrographs for the Sloan Digital Sky Survey and the Baryon Oscillation Spectroscopic Survey

scientific article published in Astronomical Journal

The past 10 years of gastroenterology and hepatology-reflections and predictions

scientific article published on 07 October 2014

The seventh data release of the Sloan Digital Sky Survey

scientific article published in 2009

Therapeutic targeting of the PDGF and TGF-beta-signaling pathways in hepatic stellate cells by PTK787/ZK22258

scientific article published on 10 August 2009

Transcription factor KLF6 upregulates expression of metalloprotease MMP14 and subsequent release of soluble endoglin during vascular injury

scientific article published on 5 February 2016

Transcriptional activation of endoglin and transforming growth factor-beta signaling components by cooperative interaction between Sp1 and KLF6: their potential role in the response to vascular injury

scientific article (publication date: December 2002)

Transcriptional activation of the insulin-like growth factor I receptor gene by the Kruppel-like factor 6 (KLF6) tumor suppressor protein: potential interactions between KLF6 and p53.

scientific article

Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells.

scientific article published on 03 March 2017

Transcriptomic analysis of the effects of Toll-like receptor 4 and its ligands on the gene expression network of hepatic stellate cells

scientific article published on 18 February 2016

Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene

scientific article published on 30 January 2010

Using Big Data to Discover Diagnostics and Therapeutics for Gastrointestinal and Liver Diseases

scientific article

Vascular injury triggers Krüppel-like factor 6 mobilization and cooperation with specificity protein 1 to promote endothelial activation through upregulation of the activin receptor-like kinase 1 gene.

scientific article published on 9 October 2012

Why do so many NASH trials fail?

scientific article published on 18 May 2020

Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib.

scientific article

β-Catenin signaling in hepatocellular cancer: Implications in inflammation, fibrosis, and proliferation

scientific article published on 23 September 2013

β-PDGF receptor expressed by hepatic stellate cells regulates fibrosis in murine liver injury, but not carcinogenesis

scientific article published on 9 February 2015

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