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List of works by Catharien M. Hilkens

A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly in anti-citrullinated peptide antibody-negative disease.

scientific article

A document-centric approach for developing the tolAPC ontology

scientific article published on 28 November 2017

A negative feedback loop mediated by STAT3 limits human Th17 responses.

scientific article published on 27 June 2014

A novel paradigm for dendritic cells as effectors of cartilage destruction.

scientific article published on 5 March 2009

A region encompassing the FERM domain of Jak1 is necessary for binding to the cytokine receptor gp130

scientific article published on 01 September 2001

AIRE is not essential for the induction of human tolerogenic dendritic cells

scientific article published on 25 February 2016

Adult Human Fibroblasts Are Potent Immunoregulatory Cells and Functionally Equivalent to Mesenchymal Stem Cells

scientific article published on 01 August 2007

Airway epithelial cells as guardians of immune homeostasis?

scientific article published on 01 November 2009

Atopic allergy: a failure of antigen-presenting cells to properly polarize helper T cells?

scientific article

Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis

scientific article published on 26 April 2016

Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells.

scientific article published on 21 January 2009

CMV seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study

scientific article published on 22 December 2015

Cell-based Tolerogenic Therapy, Experience from Animal Models of Multiple Sclerosis, Type 1 Diabetes and Rheumatoid Arthritis.

scientific article published on 14 February 2017

Cell-type and donor-specific transcriptional responses to interferon-alpha. Use of customized gene arrays.

scientific article

Clinical Use of Tolerogenic Dendritic Cells-Harmonization Approach in European Collaborative Effort

scientific article

Dendritic Cells, Obtained from Peripheral Blood Precursors in the Presence of PGE2, Promote Th2 Responses ⬇️

scientific article published on 01 January 1997

Dendritic cell maturation and survival are differentially regulated by TNFR1 and TNFR2.

scientific article published on 6 October 2014

Developing tolerogenic dendritic cell therapy for rheumatoid arthritis: what can we learn from mouse models?

scientific article published on September 2011

Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic Properties on Naive and Memory CD4+ T Cells

scientific article published on 19 September 2016

Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation

scientific article published on 26 January 2009

Differential responses to IFN-alpha subtypes in human T cells and dendritic cells

scientific article published on 01 November 2003

Emerging immunotherapies for rheumatoid arthritis.

scientific article published on 17 February 2014

Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: cross-sectional findings from the Newcastle 85+ Study.

scientific article

Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis.

scientific article published on 15 June 2010

High-level IL-12 production by human dendritic cells requires two signals

scientific article published on 01 November 1998

How to Deal with Polarized Th2 Cells: Exploring the Achilles’ Heel ⬇️

scientific article published on October 1, 2001

Human dendritic cells require exogenous interleukin-12-inducing factors to direct the development of naive T-helper cells toward the Th1 phenotype ⬇️

scientific article published on September 1, 1997

Hurdles in therapy with regulatory T cells

scientific article published on September 2015

IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses

scientific article published on May 2013

Immunity 12 years after alemtuzumab in RA: CD5⁺ B-cell depletion, thymus-dependent T-cell reconstitution and normal vaccine responses.

scientific article published on 24 March 2012

Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice.

scientific article published on January 2006

LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells.

scientific article published on 6 November 2008

Low-strength T-cell activation promotes Th17 responses.

scientific article

Macrophage proliferation distinguishes 2 subgroups of knee osteoarthritis patients

scientific article published on 24 January 2019

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

scientific article published in January 2017

Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies

scientific article

Ontology in Immunology.

scientific article published on 19 August 2016

Phenotypic and Transcriptomic Analysis of Peripheral Blood Plasmacytoid and Conventional Dendritic Cells in Early Drug Naïve Rheumatoid Arthritis.

scientific article published on 9 May 2018

Prostaglandin E2 induces the final maturation of IL-12-deficient CD1a+CD83+ dendritic cells: the levels of IL-12 are determined during the final dendritic cell maturation and are resistant to further modulation.

scientific article published in September 1998

Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease

scientific article published on 25 November 2010

Regulatory T-cell suppression of CD8+ T-cell-mediated graft-versus-host reaction requires their presence during priming

scientific article published on 01 July 2009

Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis.

scientific article

T-regulatory cells exhibit a biphasic response to prolonged endurance exercise in humans

scientific article published on 23 June 2017

Targeting of tolerogenic dendritic cells to heat-shock proteins in inflammatory arthritis

scientific article published on 14 November 2019

Targeting of tolerogenic dendritic cells towards heat shock proteins: a novel therapeutic strategy for autoimmune diseases?

scientific article published on 14 August 2017

The choice of adjuvant determines the cytokine profile of T cells in proteoglycan-induced arthritis but does not influence disease severity

scientific article published on 01 January 2013

The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy.

scientific article published on 5 October 2017

The role of antigen-presenting cells in the regulation of allergen-specific T cell responses.

scientific article published in December 1998

Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses

article

Tolerogenic dendritic cell therapy for rheumatoid arthritis: where are we now?

scientific article

Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4+ T cells partly via transforming growth factor-β1.

scientific article published on 26 September 2016

Treatment with Dexamethasone and Monophosphoryl Lipid A Removes Disease-Associated Transcriptional Signatures in Monocyte-Derived Dendritic Cells from Rheumatoid Arthritis Patients and Confers Tolerogenic Features.

scientific article published on 25 October 2016

Tumour necrosis factor alpha blockade impairs dendritic cell survival and function in rheumatoid arthritis

scientific article published on 22 September 2009

Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective

scientific article published on 22 February 2019

alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity

scientific article published on 01 September 2004

β2 Integrins As Regulators of Dendritic Cell, Monocyte, and Macrophage Function.

scientific article published on 20 December 2017

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