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List of works by Giuseppina Amadoro

A NH2 tau fragment targets neuronal mitochondria at AD synapses: possible implications for neurodegeneration.

scientific article published on January 2010

A disease with a sweet tooth: exploring the Warburg effect in Alzheimer's disease.

scientific article published on 17 March 2017

A peptide containing residues 26-44 of tau protein impairs mitochondrial oxidative phosphorylation acting at the level of the adenine nucleotide translocator.

scientific article published on 6 August 2008

AD-Related N-Terminal Truncated Tau Is Sufficient to Recapitulate In Vivo the Early Perturbations of Human Neuropathology: Implications for Immunotherapy

scientific article published on 5 March 2018

AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons

scientific article published on 24 October 2013

AMPK is activated early in cerebellar granule cells undergoing apoptosis and influences VADC1 phosphorylation status and activity

scientific article published on 22 June 2017

Apoptosis and in vitro Alzheimer disease neuronal models.

scientific article published on January 2009

Cerebrospinal fluid levels of a 20-22 kDa NH2 fragment of human tau provide a novel neuronal injury biomarker in Alzheimer's disease and other dementias.

scientific article

Dissecting the molecular mechanism by which NH2htau and Aβ1-42 peptides impair mitochondrial ANT-1 in Alzheimer disease.

scientific article published on 11 April 2013

Does the term 'trophic' actually mean anti-amyloidogenic? The case of NGF.

scientific article published on 16 April 2010

Dynamic structural determinants underlie the neurotoxicity of the N-terminal tau 26-44 peptide in Alzheimer's disease and other human tauopathies

scientific article published on 27 August 2019

Endogenous Aβ causes cell death via early tau hyperphosphorylation.

scientific article

Extracellular ADP prevents neuronal apoptosis via activation of cell antioxidant enzymes and protection of mitochondrial ANT-1.

scientific article

Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies

scientific article published on 22 April 2017

Glucose-6-phosphate tips the balance in modulating apoptosis in cerebellar granule cells.

scientific article published on 31 January 2015

Glycolytic enzyme upregulation and numbness of mitochondrial activity characterize the early phase of apoptosis in cerebellar granule cells

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models.

scientific article

Immunocytochemical distribution of NK-1 and NK-3 tachykinin receptors in isolated pancreatic acini of guinea pigs and rats.

scientific article published on 20 June 2005

Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons

scientific article published on 15 March 2017

Isolation and characterization of VGF peptides in rat brain. Role of PC1/3 and PC2 in the maturation of VGF precursor.

scientific article

Mitochondrial respiratory chain Complexes I and IV are impaired by β-amyloid via direct interaction and through Complex I-dependent ROS production, respectively.

scientific article published on 4 April 2013

Morphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathway

scientific article

NGF-Dependent Changes in Ubiquitin Homeostasis Trigger Early Cholinergic Degeneration in Cellular and Animal AD-Model

scientific article published on 13 December 2018

NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease

scientific article published on 15 February 2015

NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation.

scholarly article

Nerve growth factor as a paradigm of neurotrophins related to Alzheimer's disease.

scientific article published on April 2010

Neuroprotective coordination of cell mitophagy by the ATPase Inhibitory Factor 1.

scientific article published on 17 October 2015

Opposite Dysregulation of Fragile-X Mental Retardation Protein and Heteronuclear Ribonucleoprotein C Protein Associates with Enhanced APP Translation in Alzheimer Disease.

scientific article published on 6 June 2015

Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer's disease models

scientific article published on 06 April 2020

Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons.

scientific article published in February 2004

Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells.

scientific article published in March 2005

Substance P provides neuroprotection in cerebellar granule cells through Akt and MAPK/Erk activation: evidence for the involvement of the delayed rectifier potassium current.

scientific article published on 20 February 2007

Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer's Disease

scientific article published on 09 March 2021

The Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer's Disease Neuropathology

scientific article