Search filters

List of works by Antonio Iavarone

A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence

scientific article published in April 2018

A metabolic function of FGFR3-TACC3 gene fusions in cancer.

scientific article published on 3 January 2018

A new method of identifying glioblastoma subtypes and creation of corresponding animal models

scientific article published on 17 May 2018

A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas.

scientific article

A tree shrew glioblastoma model recapitulates features of human glioblastoma

scientific article

ATPS-37THERAPEUTIC VULNERABILITIES AND RESISTANCE MECHANISMS FOR THE PRECISION MEDICINE OF GLIOBLASTOMA.

scientific article

An ID2-dependent mechanism for VHL inactivation in cancer

scientific article published on 06 January 2016

An anatomic transcriptional atlas of human glioblastoma.

scientific article

An information theoretic method to identify combinations of genomic alterations that promote glioblastoma.

scientific article published on 4 May 2015

CNS Anticancer Drug Discovery and Development Conference White Paper.

scientific article

Clonal evolution of glioblastoma under therapy.

scientific article

Conditional deletion of Id2 or Notch1 in oligodendrocyte progenitor cells does not ameliorate disease outcome in SOD1G93A mice.

scientific article published on 3 April 2018

Control of chromosome stability by the beta-TrCP-REST-Mad2 axis

scientific article

Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma

scientific article published on 6 March 2018

Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth.

scientific article published on 28 June 2006

Detection of statistically significant network changes in complex biological networks

scientific article

Detection, Characterization, and Inhibition of FGFR-TACC Fusions in IDH Wild-type Glioma.

scientific article published on 21 January 2015

Diffuse gliomas with FGFR3-TACC3 fusion have characteristic histopathological and molecular features.

scientific article published on 4 October 2017

Distinct mechanisms of cell cycle arrest control the decision between differentiation and senescence in human neuroblastoma cells.

scientific article

E Proteins and Id2 converge on p57Kip2 to regulate cell cycle in neural cells.

scientific article published on June 2006

E protein transcription factors are required for the development of CD4(+) lineage T cells.

scientific article published on 15 March 2012

E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest

scientific article

EPIG-14EPIGENOMIC (DNA METHYLATION AND EXPRESSION) SIGNATURES DEFINE SUBSETS OF BOTH IDHmut AND IDHwt GLIOMA WITH DISTINCT CLINICAL OUTCOMES.

scientific article

Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression.

scientific article published on 16 May 2017

Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development.

scientific article published on 15 November 2013

FGFR-TACC gene fusions in human glioma

scientific article published on 16 November 2016

GE-37INTEGRATED GENOMIC ANALYSIS OF LOW GRADE GLIOMA AND GLIOBLASTOMA REVEALS MOLECULAR STRATIFICATION BY IDH STATUS ACROSS GRADES AND HISTOLOGIES.

scientific article published in November 2014

GENO-06A PAN-GLIOMA CHARACTERIZATION OF GENOMIC, EPIGENOMIC AND TRANSCRIPTOMIC ACTIVITIES REVEALS NOVEL RELATIONSHIPS BETWEEN HISTOLOGICAL SUBTYPES AND MOLECULAR SIGNATURES.

scientific article

HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation

scientific article published on 21 December 2016

Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response.

scientific article

Huwe1 Sustains Normal Ovarian Epithelial Cell Transformation and Tumor Growth through the Histone H1.3-H19 Cascade.

scientific article published on 7 July 2017

Id family of helix-loop-helix proteins in cancer

scientific article

Id proteins in neural cancer.

scientific article published on February 2004

Id2 drives differentiation and suppresses tumor formation in the intestinal epithelium.

scientific article published in October 2004

Id2 mediates tumor initiation, proliferation, and angiogenesis in Rb mutant mice.

scientific article

Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F

scientific article

MTR-19A MACROPHAGE-/MICROGLIAL-RICH TUMOR MICROENVIRONMENT MIMICS PRONEURAL TO MESENCHYMAL TRANSITION IN GLIOBLASTOMA.

scientific article

Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis.

scientific article published in August 2014

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

scientific article published on January 2016

Myc and differentiation: going against the current

scientific article published on 10 March 2014

Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer.

scientific article

RGBM: regularized gradient boosting machines for identification of the transcriptional regulators of discrete glioma subtypes.

scientific article

Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription

scientific article published on 19 April 2022

Self-Renewal Does Not Predict Tumor Growth Potential in Mouse Models of High-Grade Glioma ⬇️

scientific article published on January 17, 2012

Single-cell transcriptome analysis of lineage diversity in high-grade glioma.

scientific article

Spatiotemporal genomic architecture informs precision oncology in glioblastoma

scientific article published on 6 March 2017

The ID proteins: master regulators of cancer stem cells and tumour aggressiveness

scientific article

The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.

scientific article published on August 2009

The genomic landscape of schwannoma

scientific article published on 10 October 2016

The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland.

scientific article

The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor β in mammary epithelial cells

scientific article

The molecular landscape of glioma in patients with Neurofibromatosis 1

scientific article published on 10 December 2018

The transcriptional network for mesenchymal transformation of brain tumours.

scientific article

Transcriptional regulator Id2 is required for the CD4 T cell immune response in the development of experimental autoimmune encephalomyelitis.

scientific article published on 27 June 2012

VEGAWES: variational segmentation on whole exome sequencing for copy number detection

scientific article published on 29 September 2015

Xenopus Id3 is required downstream of Myc for the formation of multipotent neural crest progenitor cells.

scientific article

Paulina is supported by:

About Paulina

Help