List of works - Régis Millet

3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis.

scientific article

A flexible approach to the design of new potent substance P receptor ligands

scientific article published in July 2001

Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides.

scientific article

Benzo[d]thiazol-2(3H)-ones as new potent selective CB2 agonists with anti-inflammatory properties

scientific article published on 13 December 2018

Conformation of the tripeptide Cbz-Pro-Leu-Trp-OBzl(CF3)2 deduced from two-dimensional 1H-NMR and conformational energy calculations is related to its affinity for NK1-receptor.

scientific article published in June 2001

Conformational Restriction Leading to a Selective CB2 Cannabinoid Receptor Agonist Orally Active Against Colitis.

scientific article published on 4 December 2014

Corrigendum to “Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h -P2X7 receptor” [J. Chromatogr. B 986–987 (2015) 35–43]

scientific article published on 24 May 2016

Design, synthesis and biological evaluation of potent FAAH inhibitors

scientific article published on 23 April 2016

Development of novel oxazolo[5,4-d]pyrimidines as competitive CB2 neutral antagonists based on scaffold hopping.

scientific article published on 16 January 2018

Du cannabis aux agonistes sélectifs du récepteur CB2

scientific article published on 28 May 2013

Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor

scientific article published on 09 February 2015

In vitro and in vivo evaluation of two rational-designed nonpeptidic farnesyltransferase inhibitors on HT29 human colon cancer cell lines

scientific article published on 01 January 2005

Involvement of the P2X7 purinergic receptor in inflammation: an update of antagonists series since 2009 and their promising therapeutic potential.

scientific article

Microwave-mediated synthesis and manipulation of a 2-substituted-5-aminooxazole-4-carbonitrile library

New FAAH inhibitors based on 3-carboxamido-5-aryl-isoxazole scaffold that protect against experimental colitis

scientific article published on 06 May 2011

Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as new CB2 cannabinoid receptors agonists: synthesis, pharmacological properties and molecular modeling.

scientific article published in January 2006

Novel potent substance P and neurokinin A receptor antagonists. Conception, synthesis and biological evaluation of indolizine derivatives

scientific article

One- or Two-Step Synthesis of C-8 and N-9 Substituted Purines

scientific article published in December 2017

Potent farnesyltransferase inhibitors with 1,4-diazepane scaffolds as novel destabilizing microtubule agents in hormone-resistant prostate cancer.

scientific article published on 7 February 2011

Recent advances in the development of selective CB(2) agonists as promising anti-inflammatory agents.

scientific article published on January 2012

Scaffold hopping strategy toward original pyrazolines as selective CB2 receptor ligands

scientific article published on 26 October 2012

Small scale separation of isoxazole structurally related analogues by chiral supercritical fluid chromatography

scientific article published on 12 May 2017

Solid-phase synthesis and pharmacological evaluation of a library of peptidomimetics as potential farnesyltransferase inhibitors: an approach to new lead compounds.

scientific article published on 2 May 2006

Switching cannabinoid response from CB2 agonists to FAAH inhibitors

scientific article published on 28 January 2014

Switching invariant natural killer T (iNKT) cell response from anticancerous to anti-inflammatory effect: molecular bases.

scientific article published on 12 February 2014

Synthesis and biological activity of N-aroyl-tetrahydro-gamma-carbolines.

scientific article

Synthesis and biological evaluation of ferrocene-based cannabinoid receptor 2 ligands.

scientific article

Synthesis of 2,3 and 4,5-Dihydro-hydroxy-isoxazoles and Isoxazoles Under Different pH Conditions

Synthesis of Bioorganometallic Nanomolar-Potent CB2 Agonists Containing a Ferrocene Unit

Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators.

scientific article published on 27 February 2012

Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors.

scientific article published on 21 October 2016

Therapeutical potential of CB₂ receptors in immune-related diseases

scientific article

Virtual screening of CB(2) receptor agonists from bayesian network and high-throughput docking: structural insights into agonist-modulated GPCR features.

scientific article

List of works by Régis Millet

3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis.

A flexible approach to the design of new potent substance P receptor ligands

Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides.

Benzo[d]thiazol-2(3H)-ones as new potent selective CB2 agonists with anti-inflammatory properties

Conformation of the tripeptide Cbz-Pro-Leu-Trp-OBzl(CF3)2 deduced from two-dimensional 1H-NMR and conformational energy calculations is related to its affinity for NK1-receptor.

Conformational Restriction Leading to a Selective CB2 Cannabinoid Receptor Agonist Orally Active Against Colitis.

Corrigendum to “Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h -P2X7 receptor” [J. Chromatogr. B 986–987 (2015) 35–43]

Design, synthesis and biological evaluation of potent FAAH inhibitors

Development of novel oxazolo[5,4-d]pyrimidines as competitive CB2 neutral antagonists based on scaffold hopping.

Du cannabis aux agonistes sélectifs du récepteur CB2

Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor

In vitro and in vivo evaluation of two rational-designed nonpeptidic farnesyltransferase inhibitors on HT29 human colon cancer cell lines

Involvement of the P2X7 purinergic receptor in inflammation: an update of antagonists series since 2009 and their promising therapeutic potential.

Microwave-mediated synthesis and manipulation of a 2-substituted-5-aminooxazole-4-carbonitrile library

New FAAH inhibitors based on 3-carboxamido-5-aryl-isoxazole scaffold that protect against experimental colitis

Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as new CB2 cannabinoid receptors agonists: synthesis, pharmacological properties and molecular modeling.

Novel potent substance P and neurokinin A receptor antagonists. Conception, synthesis and biological evaluation of indolizine derivatives

One- or Two-Step Synthesis of C-8 and N-9 Substituted Purines

Potent farnesyltransferase inhibitors with 1,4-diazepane scaffolds as novel destabilizing microtubule agents in hormone-resistant prostate cancer.

Recent advances in the development of selective CB(2) agonists as promising anti-inflammatory agents.

Scaffold hopping strategy toward original pyrazolines as selective CB2 receptor ligands

Small scale separation of isoxazole structurally related analogues by chiral supercritical fluid chromatography

Solid-phase synthesis and pharmacological evaluation of a library of peptidomimetics as potential farnesyltransferase inhibitors: an approach to new lead compounds.

Switching cannabinoid response from CB2 agonists to FAAH inhibitors

Switching invariant natural killer T (iNKT) cell response from anticancerous to anti-inflammatory effect: molecular bases.

Synthesis and biological activity of N-aroyl-tetrahydro-gamma-carbolines.

Synthesis and biological evaluation of ferrocene-based cannabinoid receptor 2 ligands.

Synthesis of 2,3 and 4,5-Dihydro-hydroxy-isoxazoles and Isoxazoles Under Different pH Conditions

Synthesis of Bioorganometallic Nanomolar-Potent CB2 Agonists Containing a Ferrocene Unit

Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators.

Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors.

Therapeutical potential of CB₂ receptors in immune-related diseases

Virtual screening of CB(2) receptor agonists from bayesian network and high-throughput docking: structural insights into agonist-modulated GPCR features.