Search filters

List of works by Sangeeta N. Bhatia

A Macro-to-Micro Interface for the Control of Cellular Organization

scientific article published in April 2014

A biophysical indicator of vaso-occlusive risk in sickle cell disease

scientific article

A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis

scientific article

A computational framework for identifying design guidelines to increase the penetration of targeted nanoparticles into tumors

scientific article

A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries.

scientific article published on 28 June 2016

Aberrant glycosylation promotes lung cancer metastasis through adhesion to galectins in the metastatic niche

scientific article

Acidification of Tumor at Stromal Boundaries Drives Transcriptome Alterations Associated with Aggressive Phenotypes

scientific article published on 12 February 2019

Activatable zymography probes enable in situ localization of protease dysregulation in cancer

scientific article published on 26 October 2020

An extracellular matrix microarray for probing cellular differentiation

scientific article

Anisotropic stretch-induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomers

scientific article

Assessing porcine liver-derived biomatrix for hepatic tissue engineering

scientific article published in July 2004

Assessment of hepatocellular function within PEG hydrogels

scientific article published on 18 September 2006

Biodegradable luminescent porous silicon nanoparticles for in vivo applications

scientific article

Bioengineering Methods for Analysis of Cells In Vitro ⬇️

scientific article published on January 1, 2012

Biomimetic amplification of nanoparticle homing to tumors

scientific article

Biomolecular screening with encoded porous-silicon photonic crystals.

scientific article published in September 2002

Bioresponsive mesoporous silica nanoparticles for triggered drug release

scientific article published on 18 November 2011

Cancer Cell-Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma

scientific article published on 06 February 2020

Cancer vulnerabilities unveiled by genomic loss

scientific article

Cell and tissue engineering for liver disease

scientific article published on July 2014

Classification of prostate cancer using a protease activity nanosensor library.

scientific article published on 20 August 2018

Combinatorial signaling microenvironments for studying stem cell fate

scientific article

Comparison of Modular PEG Incorporation Strategies for Stabilization of Peptide-siRNA Nanocomplexes.

scientific article published on September 2016

Computationally guided photothermal tumor therapy using long-circulating gold nanorod antennas

scientific article published on 14 April 2009

Cooperative nanomaterial system to sensitize, target, and treat tumors

scientific article

Cooperative nanoparticles for tumor detection and photothermally triggered drug delivery

scientific article

Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy

scientific article

DNA-templated assembly of droplet-derived PEG microtissues

scientific article

Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes

scientific article

Degradable hydrogels derived from PEG-diacrylamide for hepatic tissue engineering

scientific article published on 07 April 2015

Depolarization signatures map gold nanorods within biological tissue.

scientific article

Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors

scientific article

Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance

scientific article published on 26 April 2009

Disease detection by ultrasensitive quantification of microdosed synthetic urinary biomarkers.

scientific article

Drug-induced amplification of nanoparticle targeting to tumors.

scientific article published on 23 September 2014

Effect of nanoparticle conjugation on gene silencing by RNA interference

scientific article published on June 2010

Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors.

scientific article

Engineering liver therapies for the future

scientific article

Engineering synthetic breath biomarkers for respiratory disease

scientific article published on 20 July 2020

Engineering tissues for in vitro applications

scientific article published on 15 September 2006

Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels

scientific article published on 28 December 2006

Fabrication of PLGA scaffolds using soft lithography and microsyringe deposition

scientific article published in June 2003

Fabrication of three-dimensional tissues.

scientific article published on January 2007

Flow-based pipeline for systematic modulation and analysis of 3D tumor microenvironments

scientific article published on 05 April 2013

Formation of steady-state oxygen gradients in vitro: application to liver zonation

scientific article published in May 2003

Functional delivery of siRNA in mice using dendriworms

scientific article

Genetic Circuits in Salmonella typhimurium ⬇️

scientific article published on August 9, 2012

Genetic Encoding of Targeted Magnetic Resonance Imaging Contrast Agents for Tumor Imaging

scientific article published on 22 January 2020

Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer

scientific article published on 28 June 2018

Geometric and material determinants of patterning efficiency by dielectrophoresis

scientific article

Geometric control of vascular networks to enhance engineered tissue integration and function

scientific article published on 22 April 2013

High-throughput analysis of signals regulating stem cell fate and function

scientific article

Humanized mice with ectopic artificial liver tissues.

scientific article

Hypoxic inhibition of 3-methylcholanthrene-induced CYP1A1 expression is independent of HIF-1alpha

scientific article published in January 2005

Identification and characterization of receptor-specific peptides for siRNA delivery

scientific article

In Vivo Gene Expression Dynamics of Tumor-Targeted Bacteria.

scientific article

In vitro liver tissue model established from transgenic mice: role of HIF-1alpha on hypoxic gene expression.

scientific article

In vitro zonation and toxicity in a hepatocyte bioreactor

scientific article

In vivo tumor cell targeting with "click" nanoparticles

scientific article

In-silico patterning of vascular mesenchymal cells in three dimensions

scientific article

Laminin and fibronectin modulate inner ear spiral ganglion neurite outgrowth in an in vitro alternate choice assay.

scientific article published in November 2007

Ligand-clustered "patchy" nanoparticles for modulated cellular uptake and in vivo tumor targeting ⬇️

scientific article published on September 24, 2010

Local heating of discrete droplets using magnetic porous silicon-based photonic crystals

scientific article

Magnetic Iron Oxide Nanoworms for Tumor Targeting and Imaging

scientific article

Magnetically Actuated Protease Sensors for in Vivo Tumor Profiling

scientific article

Manipulation of liquid droplets using amphiphilic, magnetic one-dimensional photonic crystal chaperones

scientific article published on 7 November 2004

Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination

scientific article published on 01 July 2020

Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease

scientific article published on 16 December 2012

Mathematical framework for activity-based cancer biomarkers

scientific article

Measuring growth and gene expression dynamics of tumor-targeted S. typhimurium bacteria

scientific article published on 06 July 2013

Mechanisms of cooperation in cancer nanomedicine: towards systems nanotechnology

scientific article published on 30 July 2014

Micellar hybrid nanoparticles for simultaneous magnetofluorescent imaging and drug delivery

scientific article published on January 2008

Microfabricated PLGA scaffolds: a comparative study for application to tissue engineering

Microfabricated platform for studying stem cell fates

scientific article

Microfluidic organs-on-chips

scientific article published in August 2014

Microfluidics-integrated time-lapse imaging for analysis of cellular dynamics

scientific article

Micromechanical control of cell-cell interactions.

scientific article

Microscale control of cell contact and spacing via three-component surface patterning

scientific article

Mitochondrial localization and the persistent migration of epithelial cancer cells

scientific article published on May 2013

Modulation of hepatocyte phenotype in vitro via chemomechanical tuning of polyelectrolyte multilayers

scientific article

Multiphase electropatterning of cells and biomaterials

scientific article published on 18 April 2007

Multiplexed, high-throughput analysis of 3D microtissue suspensions ⬇️

scientific article published on September 1, 2010

Nanocrystal targeting in vivo

scientific article

Nanoparticle amplification via photothermal unveiling of cryptic collagen binding sites

scientific article published on 14 June 2013

Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics

scientific article published on 03 June 2020

Nanoparticle self-assembly gated by logical proteolytic triggers

scientific article published on 21 April 2007

Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells ⬇️

scientific article published on December 27, 2010

Nanoparticles that communicate in vivo to amplify tumour targeting ⬇️

scientific article published on June 19, 2011

Nanoparticles that sense thrombin activity as synthetic urinary biomarkers of thrombosis.

scientific article

Nanotechnology: emerging tools for biology and medicine

scientific article

Neuron-Targeted Nanoparticle for siRNA Delivery to Traumatic Brain Injuries

scientific article published on 18 July 2016

Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes

scientific article published on 31 October 2019

Patterning vascular networks in vivo for tissue engineering applications

scientific article published on 18 February 2015

Peptide Spiders: Peptide-Polymer Conjugates to Traffic Nucleic Acids

scientific article published on 27 July 2020

Personalized RNA-medicine for pancreatic cancer

scientific article published on 12 January 2018

Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines

scientific article published on 01 June 2020

Photo- and electropatterning of hydrogel-encapsulated living cell arrays

scientific article

Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity.

scientific article published on 13 November 2015

Plasmonic photothermal heating of intraperitoneal tumors through the use of an implanted near-infrared source

scientific article published on 20 August 2013

Point-of-care diagnostics for noncommunicable diseases using synthetic urinary biomarkers and paper microfluidics

scientific article published on 24 February 2014

Polymer replicas of photonic porous silicon for sensing and drug delivery applications

scientific article published in March 2003

Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections

scientific article published on 12 July 2017

Porous silicon-graphene oxide core-shell nanoparticles for targeted delivery of siRNA to the injured brain

scientific article published on 14 June 2016

Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies

scientific article published on 18 January 2024

Probing the Cytotoxicity Of Semiconductor Quantum Dots

scientific article published on 10 December 2003

Probing the role of multicellular organization in three-dimensional microenvironments

scientific article

Programmable probiotics for detection of cancer in urine.

scientific article published in May 2015

Protease activity sensors noninvasively classify bacterial infections and antibiotic responses

article

Protease-triggered unveiling of bioactive nanoparticles

scientific article published on September 2008

Proteolytic actuation of nanoparticle self-assembly

scientific article published on May 2006

Quantum dots to monitor RNAi delivery and improve gene silencing

scientific article

Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues

scientific article

Renal clearable catalytic gold nanoclusters for in vivo disease monitoring

scientific article published on 02 September 2019

SERS-Coded Gold Nanorods as a Multifunctional Platform for Densely Multiplexed Near-Infrared Imaging and Photothermal Heating.

scientific article

Self-Sealing Porous Silicon-Calcium Silicate Core-Shell Nanoparticles for Targeted siRNA Delivery to the Injured Brain.

scientific article published on 6 July 2016

Self-titrating anticoagulant nanocomplexes that restore homeostatic regulation of the coagulation cascade.

scientific article

Silicon microchips for manipulating cell-cell interaction

scientific article published on 30 August 2007

Silicon nanoparticles as hyperpolarized magnetic resonance imaging agents

scientific article

Single cell trapping and DNA damage analysis using microwell arrays

scientific article

Smart nanosystems: Bio-inspired technologies that interact with the host environment

scientific article

Statistical dynamics of flowing red blood cells by morphological image processing ⬇️

scientific article

Sustained-release synthetic biomarkers for monitoring thrombosis and inflammation using point-of-care compatible readouts.

scientific article

Synchronized cycles of bacterial lysis for in vivo delivery

scientific article published on 20 July 2016

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

scientific article

Systematic surface engineering of magnetic nanoworms for in vivo tumor targeting

scientific article

T-cadherin modulates hepatocyte functions in vitro ⬇️

scientific article published on 17 July 2008

Targeted quantum dot conjugates for siRNA delivery

scientific article published on 14 July 2007

Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4

scientific article published on August 2012

Targeting of drugs and nanoparticles to tumors

scientific article

The compatibility of hepatocytes with chemically modified porous silicon with reference to in vitro biosensors

scientific article published on 08 October 2008

The pipeline still leaks and more than you think: a status report on gender diversity in biomedical engineering

scientific article published on 17 February 2010

The smart Petri dish: a nanostructured photonic crystal for real-time monitoring of living cells

scientific article

Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing

scientific article published on 07 January 2020

Three-dimensional tissue fabrication

scientific article published in September 2004

Tissue-specific gene delivery via nanoparticle coating

scientific article published on 21 October 2009

Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer

scientific article published on 03 September 2019

Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas

scientific article published on 10 October 2017

Ultrasensitive tumour-penetrating nanosensors of protease activity

scientific article published on 10 April 2017

Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling

scientific article published on 01 April 2020

iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer

scientific article published on 10 August 2018

Paulina is supported by:

About Paulina

Help