List of works - Yasushi Ogawa

A novel IL36RN/IL1F5 homozygous nonsense mutation, p.Arg10X, in a Japanese patient with adult-onset generalized pustular psoriasis

scientific article published on 20 June 2012

A palindromic motif in the -2084 to -2078 upstream region is essential for ABCA12 promoter function in cultured human keratinocytes.

scientific article

Anti-PM/Scl antibodies are found in Japanese patients with various systemic autoimmune conditions besides myositis and scleroderma.

scientific article published on 11 March 2015

Anti-p80 coilin autoantibodies react with a conserved epitope and are associated with anti-DFS70/LEDGF autoantibodies

scientific article published on 24 October 2005

Autoantibodies to DFS70/LEDGF are increased in alopecia areata patients

scientific article

Autoantibody to thioredoxin reductase in an ovarian cancer patient

scientific article published on 01 January 1998

Autoantigenicity of DFS70 is restricted to the conformational epitope of C-terminal alpha-helical domain

scientific article

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

scientific article

Biallelic Mutations in KDSR Disrupt Ceramide Synthesis and Result in a Spectrum of Keratinization Disorders Associated with Thrombocytopenia

scientific article published on 31 July 2017

Challenges to congenital genetic disorders with “RNA-targeting” chemical compounds ⬇️

scientific article published on February 9, 2012

Design and synthesis of a potent inhibitor of class 1 DYRK kinases as a suppressor of adipogenesis

scientific article published on 14 June 2015

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A

scientific article

Discovery of novel immunostimulants by dendritic-cell-based functional screening.

scientific article published on 7 July 2005

Epstein-Barr Virus-associated Natural Killer/T-cell Lymphoma in a Patient Receiving Therapy with Anti-Tumour Necrosis Factor and Thiopurine

scientific article published on 30 August 2016

Establishment of an ELISA to detect anti-glycyl-tRNA synthetase antibody (anti-EJ), a serological marker of dermatomyositis/polymyositis and interstitial lung disease.

scientific article

HLA-associated production of anti-DFS70/LEDGF autoantibodies and systemic autoimmune disease

scientific article published on 19 May 2006

High survival rate of harlequin ichthyosis in Japan

scientific article published on 01 February 2014

Identification of novel pharmacological activities of an antifungal agent, nystatin, to promote dendritic cell maturation.

scientific article published on February 2006

IgE-independent pathophysiology of severe atopic dermatitis demonstrated in an IgE-deficient patient.

scientific article published on 21 January 2016

Image Gallery: Palmoplantar hyperkeratosis in dermatomyositis with anti-PM/Scl antibodies

scientific article published on 01 May 2017

Image Gallery: Unilaterally dominant acrokeratoelastoidosis (punctate palmoplantar keratoderma type 3).

scientific article

Intravital imaging of IL-1beta production in skin.

scientific article published on 11 February 2010

LEDGF/DFS70 activates the MK2/IL6/STAT3 pathway in HaCaT.

scientific article published on 20 May 2011

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.

scientific article published on 26 May 2011

More than keratitis, ichthyosis, and deafness: multisystem effects of lethal GJB2 mutations

scientific article published on 02 October 2018

Non-infectious Panniculitis during Hydroxyurea Therapy in a Patient with Myeloproliferative Disease

scientific article

Nuclear envelope localization of Ran-binding protein 2 and Ran-GTPase-activating protein 1 in psoriatic epidermal keratinocytes

scientific article published on February 2014

Overexpression of LEDGF/DFS70 induces IL-6 via p38 activation in HaCaT cells, similar to that seen in the psoriatic condition.

scientific article published on 15 July 2010

Pansclerotic morphea associated with hypohidrosis and anti-M3 muscarinic acetylcholine receptor antibodies

scientific article published on 4 October 2017

Pigmented macules in Waardenburg syndrome type 2 due to KITLG mutation.

scientific article

Pityriasis Rubra Pilaris Type V as an Autoinflammatory Disease by CARD14 Mutations

scientific article published on 19 October 2016

Possible roles of barrier-to-autointegration factor 1 in regulation of keratinocyte differentiation and proliferation.

scientific article published on 19 April 2013

Regulation of fibroblast growth factor-23 signaling by klotho

scientific journal article

Revertant mutation releases confined lethal mutation, opening Pandora's box: a novel genetic pathogenesis

scientific article

Severe chilblain lupus is associated with heterozygous missense mutations of catalytic amino acids or their adjacent mutations in the exonuclease domains of 3'-repair exonuclease 1.

scientific article

Survey on patients with undiagnosed diseases in Japan: potential patient numbers benefiting from Japan's initiative on rare and undiagnosed diseases (IRUD)

scientific article published on 20 November 2018

The majority of generalized pustular psoriasis without psoriasis vulgaris is caused by deficiency of interleukin-36 receptor antagonist.

scientific article published on 22 May 2013

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

scientific article

Unilateral generalized linear porokeratosis with nail dystrophy.

scientific article published on 21 November 2015

List of works by Yasushi Ogawa

A novel IL36RN/IL1F5 homozygous nonsense mutation, p.Arg10X, in a Japanese patient with adult-onset generalized pustular psoriasis

A palindromic motif in the -2084 to -2078 upstream region is essential for ABCA12 promoter function in cultured human keratinocytes.

Anti-PM/Scl antibodies are found in Japanese patients with various systemic autoimmune conditions besides myositis and scleroderma.

Anti-p80 coilin autoantibodies react with a conserved epitope and are associated with anti-DFS70/LEDGF autoantibodies

Autoantibodies to DFS70/LEDGF are increased in alopecia areata patients

Autoantibody to thioredoxin reductase in an ovarian cancer patient

Autoantigenicity of DFS70 is restricted to the conformational epitope of C-terminal alpha-helical domain

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

Biallelic Mutations in KDSR Disrupt Ceramide Synthesis and Result in a Spectrum of Keratinization Disorders Associated with Thrombocytopenia

Challenges to congenital genetic disorders with “RNA-targeting” chemical compounds ⬇️

Design and synthesis of a potent inhibitor of class 1 DYRK kinases as a suppressor of adipogenesis

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A

Discovery of novel immunostimulants by dendritic-cell-based functional screening.

Epstein-Barr Virus-associated Natural Killer/T-cell Lymphoma in a Patient Receiving Therapy with Anti-Tumour Necrosis Factor and Thiopurine

Establishment of an ELISA to detect anti-glycyl-tRNA synthetase antibody (anti-EJ), a serological marker of dermatomyositis/polymyositis and interstitial lung disease.

HLA-associated production of anti-DFS70/LEDGF autoantibodies and systemic autoimmune disease

High survival rate of harlequin ichthyosis in Japan

Identification of novel pharmacological activities of an antifungal agent, nystatin, to promote dendritic cell maturation.

IgE-independent pathophysiology of severe atopic dermatitis demonstrated in an IgE-deficient patient.

Image Gallery: Palmoplantar hyperkeratosis in dermatomyositis with anti-PM/Scl antibodies

Image Gallery: Unilaterally dominant acrokeratoelastoidosis (punctate palmoplantar keratoderma type 3).

Intravital imaging of IL-1beta production in skin.

LEDGF/DFS70 activates the MK2/IL6/STAT3 pathway in HaCaT.

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.

More than keratitis, ichthyosis, and deafness: multisystem effects of lethal GJB2 mutations

Non-infectious Panniculitis during Hydroxyurea Therapy in a Patient with Myeloproliferative Disease

Nuclear envelope localization of Ran-binding protein 2 and Ran-GTPase-activating protein 1 in psoriatic epidermal keratinocytes

Overexpression of LEDGF/DFS70 induces IL-6 via p38 activation in HaCaT cells, similar to that seen in the psoriatic condition.

Pansclerotic morphea associated with hypohidrosis and anti-M3 muscarinic acetylcholine receptor antibodies

Pigmented macules in Waardenburg syndrome type 2 due to KITLG mutation.

Pityriasis Rubra Pilaris Type V as an Autoinflammatory Disease by CARD14 Mutations

Possible roles of barrier-to-autointegration factor 1 in regulation of keratinocyte differentiation and proliferation.

Regulation of fibroblast growth factor-23 signaling by klotho

Revertant mutation releases confined lethal mutation, opening Pandora's box: a novel genetic pathogenesis

Severe chilblain lupus is associated with heterozygous missense mutations of catalytic amino acids or their adjacent mutations in the exonuclease domains of 3'-repair exonuclease 1.

Survey on patients with undiagnosed diseases in Japan: potential patient numbers benefiting from Japan's initiative on rare and undiagnosed diseases (IRUD)

The majority of generalized pustular psoriasis without psoriasis vulgaris is caused by deficiency of interleukin-36 receptor antagonist.

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

Unilateral generalized linear porokeratosis with nail dystrophy.