List of works - Eiji Ohashi

Conserved interaction of Ctf18-RFC with DNA polymerase ε is critical for maintenance of genome stability in Saccharomyces cerevisiae.

scientific article published on 14 March 2016

Functions of Multiple Clamp and Clamp-Loader Complexes in Eukaryotic DNA Replication

scientific article published in January 2017

Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ε efficiently loads the PCNA sliding clamp.

scientific article published on 13 February 2017

Identification of a novel REV1-interacting motif necessary for DNA polymerase kappa function.

scientific article published on 6 January 2009

Interaction between Rad9-Hus1-Rad1 and TopBP1 activates ATR-ATRIP and promotes TopBP1 recruitment to sites of UV-damage.

scientific article

Interaction of hREV1 with three human Y-family DNA polymerases

scientific article

Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells.

scientific article published on 21 January 2009

Intramolecular Binding of the Rad9 C Terminus in the Checkpoint Clamp Rad9-Hus1-Rad1 Is Closely Linked with Its DNA Binding.

scientific article published on 18 June 2015

Mammalian Pol kappa: regulation of its expression and lesion substrates.

scientific article

Overlapping in short motif sequences for binding to human REV7 and MAD2 proteins.

scientific article published on 19 January 2010

Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases

scientific article published on 01 February 2009

Rapid Purification and Characterization of Mutant Origin Recognition Complexes in Saccharomyces cerevisiae.

scientific article published on 18 April 2016

Specific basic patch-dependent multimerization of Saccharomyces cerevisiae ORC on single-stranded DNA promotes ATP hydrolysis

scientific article published on 10 July 2019

Specific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues

scientific article

Stable interaction between the human proliferating cell nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA polymerase {epsilon} is mediated by the cohesion-specific subunits, Ctf18, Dcc1, and Ctf8

scientific article

Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen

scientific article

Structure of the RAD9-RAD1-HUS1 checkpoint clamp bound to RHINO sheds light on the other side of the DNA clamp

scientific article published on 27 November 2019

The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled site

scientific article (publication date: 16 March 2012)

Translesion DNA synthesis catalyzed by human pol eta and pol kappa across 1,N6-ethenodeoxyadenosine.

scientific article published on 16 March 2001

Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota

scientific article

Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).

scientific article

Translesional Synthesis Past Acetylaminofluorene-Derived DNA Adducts Catalyzed by Human DNA Polymerase κ and Escherichia coli DNA Polymerase IV ⬇️

scientific article published on December 18, 2001

Two serine phosphorylation sites in the C-terminus of Rad9 are critical for 9-1-1 binding to TopBP1 and activation of the DNA damage checkpoint response in HeLa cells.

scientific article

Ubiquitin mediates the physical and functional interaction between human DNA polymerases η and ι

scientific article published on 16 December 2012

List of works by Eiji Ohashi

Conserved interaction of Ctf18-RFC with DNA polymerase ε is critical for maintenance of genome stability in Saccharomyces cerevisiae.

Functions of Multiple Clamp and Clamp-Loader Complexes in Eukaryotic DNA Replication

Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ε efficiently loads the PCNA sliding clamp.

Identification of a novel REV1-interacting motif necessary for DNA polymerase kappa function.

Interaction between Rad9-Hus1-Rad1 and TopBP1 activates ATR-ATRIP and promotes TopBP1 recruitment to sites of UV-damage.

Interaction of hREV1 with three human Y-family DNA polymerases

Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells.

Intramolecular Binding of the Rad9 C Terminus in the Checkpoint Clamp Rad9-Hus1-Rad1 Is Closely Linked with Its DNA Binding.

Mammalian Pol kappa: regulation of its expression and lesion substrates.

Overlapping in short motif sequences for binding to human REV7 and MAD2 proteins.

Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases

Rapid Purification and Characterization of Mutant Origin Recognition Complexes in Saccharomyces cerevisiae.

Specific basic patch-dependent multimerization of Saccharomyces cerevisiae ORC on single-stranded DNA promotes ATP hydrolysis

Specific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues

Stable interaction between the human proliferating cell nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA polymerase {epsilon} is mediated by the cohesion-specific subunits, Ctf18, Dcc1, and Ctf8

Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen

Structure of the RAD9-RAD1-HUS1 checkpoint clamp bound to RHINO sheds light on the other side of the DNA clamp

The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled site

Translesion DNA synthesis catalyzed by human pol eta and pol kappa across 1,N6-ethenodeoxyadenosine.

Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota

Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).

Translesional Synthesis Past Acetylaminofluorene-Derived DNA Adducts Catalyzed by Human DNA Polymerase κ and Escherichia coli DNA Polymerase IV ⬇️

Two serine phosphorylation sites in the C-terminus of Rad9 are critical for 9-1-1 binding to TopBP1 and activation of the DNA damage checkpoint response in HeLa cells.

Ubiquitin mediates the physical and functional interaction between human DNA polymerases η and ι