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List of works by Kimmo K Lehtimäki

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease

scientific article published on 01 July 2019

Assignment of 1H nuclear magnetic resonance visible polyunsaturated fatty acids in BT4C gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death

scientific article

Caspase-6 activity in a BACHD mouse modulates steady-state levels of mutant huntingtin protein but is not necessary for production of a 586 amino acid proteolytic fragment.

scientific article

Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.

scientific article

Diffusion tensor MRI with tract-based spatial statistics and histology reveals undiscovered lesioned areas in kainate model of epilepsy in rat

scientific article published on 12 January 2011

Effect of Ibuprofen on Skeletal Muscle of Dysferlin-null Mice.

scientific article published on 28 December 2017

Genetic deletion of transglutaminase 2 does not rescue the phenotypic deficits observed in R6/2 and zQ175 mouse models of Huntington's disease.

scientific article

High-resolution magic-angle-spinning 1H NMR spectroscopy reveals different responses in choline-containing metabolites upon gene therapy-induced programmed cell death in rat brain glioma.

scientific article

Hip region muscular dystrophy and emergence of motor deficits in dysferlin-deficient Bla/J mice

scientific article published on March 2017

Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro.

scientific article

Multimodal MRI assessment of damage and plasticity caused by status epilepticus in the rat brain.

scientific article

Novel magnetic resonance imaging contrasts for monitoring response to gene therapy in rat glioma

scientific article published in November 2003

Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington's Disease Models.

scientific article published on 25 November 2016

Progressive volume loss and white matter degeneration in cstb-deficient mice: a diffusion tensor and longitudinal volumetry MRI study

scientific article

Stem cell profiling by nuclear magnetic resonance spectroscopy.

scientific article published on September 2006

Systemic Delivery of Dysferlin Overlap Vectors Provides Long-Term Gene Expression and Functional Improvement for Dysferlinopathy

scientific article published on 14 July 2017

The PDE1/5 Inhibitor SCH-51866 Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington's Disease

scientific article published on 13 February 2014

The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain.

scientific article

The novel KMO inhibitor CHDI-340246 leads to a restoration of electrophysiological alterations in mouse models of Huntington's disease.

scientific article published on 6 May 2016

Water diffusion in a rat glioma during ganciclovir-thymidine kinase gene therapy-induced programmed cell death in vivo: correlation with cell density.

scientific article

mNos2 deletion and human NOS2 replacement in Alzheimer disease models

scientific article

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