Search filters

List of works by Frank D Waldron-Lynch

Adaptive dose-finding designs to identify multiple doses that achieve multiple response targets.

scientific article published on 29 November 2013

Adjunctive prandial or biphasic insulin for type 2 diabetes improved glycaemic control but increased hypoglycaemia and weight gain.

scientific article published in June 2008

Analysis of Human Biologics With a Mouse Skin Transplant Model in Humanized Mice ⬇️

scientific article published on August 17, 2012

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial.

scientific article published on 18 July 2017

Continuous glucose monitoring: long live the revolution!

scientific article

Dress and address: patient preferences regarding doctor's style of dress and patient interaction.

scientific article published in July 2008

Effective recruitment of participants to a phase I study using the internet and publicity releases through charities and patient organisations: analysis of the adaptive study of IL-2 dose on regulatory T cells in type 1 diabetes (DILT1D).

scientific article

Fas ligand expressed in colon cancer is not associated with increased apoptosis of tumor cellsin vivo

scientific article published on 01 November 2003

Genetic analysis of the 3' untranslated region of the tumour necrosis factor shows a highly conserved region in rheumatoid arthritis affected and unaffected subjects.

scientific article

Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis.

scientific article published in September 1996

High bone turnover in Irish professional jockeys.

scientific article published on 07 March 2009

Human IL-6RhiTIGIT- CD4+CD127lowCD25+ T cells display potent in vitro suppressive capacity and a distinct Th17 profile.

scientific article

Humanized mice as a model for aberrant responses in human T cell immunotherapy.

scientific article published on 18 June 2014

Immunological biomarkers: catalysts for translational advances in autoimmune diabetes

scientific article (publication date: May 2013)

Immunomodulatory therapy to preserve pancreatic β-cell function in type 1 diabetes.

scientific article published on June 2011

In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment.

scientific article

Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2.

scientific article published on 17 August 2017

New and future immunomodulatory therapy in type 1 diabetes ⬇️

scientific article published on February 17, 2012

Protocol of the adaptive study of IL-2 dose frequency on regulatory T cells in type 1 diabetes (DILfrequency): a mechanistic, non-randomised, repeat dose, open-label, response-adaptive study

scientific article

Rationale and study design of the Adaptive study of IL-2 dose on regulatory T cells in type 1 diabetes (DILT1D): a non-randomised, open label, adaptive dose finding trial

scientific article

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial

scientific article

Relapsing and remitting severe hypoglycemia due to a monoclonal anti-insulin antibody heralding a case of multiple myeloma

scientific article published on 16 October 2012

Self-monitoring of blood glucose did not improve glycaemic control in patients with type 2 diabetes not treated with insulin.

scientific article published in February 2008

Simulation work in adaptive dose-finding designs to identify dose-intervals that achieve targets in multiple endpoints.

scientific article published on 16 November 2015

Targeting regulatory T cells with Interleukin-2 treatment in type 1 diabetes: a response-adaptive, non-randomised, open-label trial of repeat doses of Aldesleukin (DILfrequency)

Teplizumab induces human gut-tropic regulatory cells in humanized mice and patients.

scientific article

Teplizumab treatment may improve C-peptide responses in participants with type 1 diabetes after the new-onset period: a randomised controlled trial ⬇️

scientific article published on October 21, 2012

When a nephrectomy cures hypoglycaemia ⬇️

scientific article published on May 17, 2009

Paulina is supported by:

About Paulina

Help