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List of works by Terence Kin-Wah Lee

ANXA3/JNK Signaling Promotes Self-Renewal and Tumor Growth, and Its Blockade Provides a Therapeutic Target for Hepatocellular Carcinoma.

scientific article

Activation of MAPK signaling pathway is essential for Id-1 induced serum independent prostate cancer cell growth.

scientific article

Adipocytes promote prostate cancer stem cell self-renewal through amplification of the cholecystokinin autocrine loop

scientific article published on 17 December 2015

Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations.

scientific article

An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers

scientific article

Anti-CD47 antibody suppresses tumour growth and augments the effect of chemotherapy treatment in hepatocellular carcinoma.

scientific article published on 9 September 2015

Anti-tumour effects of PIM kinase inhibition on progression and chemoresistance of hepatocellular carcinoma

scientific article published on 19 June 2020

Attenuation of small-for-size liver graft injury by FTY720: significance of cell-survival Akt signaling pathway.

scientific article

Blockade of CD47-mediated cathepsin S/protease-activated receptor 2 signaling provides a therapeutic target for hepatocellular carcinoma.

scientific article published on 29 May 2014

CD133(+) liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling

scientific article published on 13 January 2012

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway.

scientific article

CD24+ Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation ⬇️

scientific article published on July 8, 2011

CRAF Methylation by PRMT6 Regulates Aerobic Glycolysis-Driven Hepatocarcinogenesis via ERK-Dependent PKM2 Nuclear Relocalization and Activation

scientific article published on 24 January 2020

Cancer Stem Cells and Their Microenvironment: Biology and Therapeutic Implications.

scientific article published on 26 February 2017

Caveolin‐1 overexpression is associated with hepatocellular carcinoma tumourigenesis and metastasis ⬇️

scientific article published on January 4, 2012

Chronic inflammation-elicited liver progenitor cell conversion to liver cancer stem cell with clinical significance

scientific article published on 17 July 2017

Clinicopathological significance of missing in metastasis B expression in hepatocellular carcinoma.

scientific article

Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/β-catenin pathway.

scientific article

Deficiency in Embryonic Stem Cell Marker Reduced Expression 1 Activates Mitogen-Activated Protein Kinase Kinase 6-Dependent p38 Mitogen-Activated Protein Kinase Signaling to Drive Hepatocarcinogenesis

scientific article published on 04 November 2019

Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma.

scientific article

Doxorubicin-induced apoptosis and chemosensitivity in hepatoma cell lines.

scientific article published in January 2002

Effects of a novel immunomodulating agent, FTY720, on tumor growth and angiogenesis in hepatocellular carcinoma.

scientific article published in September 2005

Effects of the intermittent Pringle manoeuvre on hepatic gene expression and ultrastructure in a randomized clinical study.

scientific article published on February 2003

FK 409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway.

scientific article published in July 2004

FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers.

scientific article published in January 2005

Fascin over-expression is associated with aggressiveness of oral squamous cell carcinoma

scientific article published on 11 May 2007

Fat-derived hormone adiponectin combined with FTY720 significantly improves small-for-size fatty liver graft survival.

scientific article published in March 2006

Gene delivery using a receptor-mediated gene transfer system targeted to hepatocellular carcinoma cells.

scientific article

IRAK1 augments cancer stemness and drug resistance via the AP-1/AKR1B10 signaling cascade in hepatocellular carcinoma.

scientific article published on 26 February 2018

Id-1 induces proteasome-dependent degradation of the HBX protein

scientific article

Identification of a novel inhibitor of differentiation-1 (ID-1) binding partner, caveolin-1, and its role in epithelial-mesenchymal transition and resistance to apoptosis in prostate cancer cells

scientific article

Ischemia-reperfusion of small liver remnant promotes liver tumor growth and metastases--activation of cell invasion and migration pathways.

scientific article published on December 2007

Liver tumor-initiating cells as a therapeutic target for hepatocellular carcinoma.

scientific article published on 08 May 2012

Lupeol suppresses cisplatin-induced nuclear factor-kappaB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model.

scientific article

Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation

scientific article published on October 26, 2010

Network-Pharmacology-Based Study on Active Phytochemicals and Molecular Mechanism of <i>Cnidium monnieri</i> in Treating Hepatocellular Carcinoma

scientific article published on 12 May 2022

Notch Inhibitor PF-03084014 Inhibits Hepatocellular Carcinoma Growth and Metastasis via Suppression of Cancer Stemness due to Reduced Activation of Notch1-Stat3.

scientific article published on 18 May 2017

Nuclear factor kappa B-mediated CD47 up-regulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma in mice

scientific article published on 03 June 2015

Octamer 4/microRNA-1246 signaling axis drives Wnt/β-catenin activation in liver cancer stem cells.

scientific article published on 17 September 2016

Over-expression of Id-1 induces cell proliferation in hepatocellular carcinoma through inactivation of p16INK4a/RB pathway.

scientific article

Overriding Adaptive Resistance to Sorafenib Through Combination Therapy With Src Homology 2 Domain-Containing Phosphatase 2 Blockade in Hepatocellular Carcinoma

scientific article published on 14 October 2019

PIN1 expression contributes to hepatic carcinogenesis.

scientific article published on September 2006

Polysaccharopeptide enhanced the anti-cancer effect of gamma-tocotrienol through activation of AMPK.

scientific article

Rapamycin attenuates liver graft injury in cirrhotic recipient--the significance of down-regulation of Rho-ROCK-VEGF pathway

scientific article published on 01 April 2006

Regulatory role of miR-142-3p on the functional hepatic cancer stem cell marker CD133.

scientific article published on July 2014

Shp2 promotes liver cancer stem cell expansion by augmenting β-catenin signaling and predicts chemotherapeutic response of patients.

scientific article published on 5 November 2016

Signal transducers and activators of transcription 5b activation enhances hepatocellular carcinoma aggressiveness through induction of epithelial-mesenchymal transition.

scientific article published on October 2006

Significance of the Rac signaling pathway in HCC cell motility: implications for a new therapeutic target.

scientific article

Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/β-catenin signaling

scientific article published on 19 April 2016

Stearoyl-CoA desaturase regulates sorafenib resistance via modulation of ER stress-induced differentiation.

scientific article

Suppression of tumorigenesis and metastasis of hepatocellular carcinoma by shRNA interference targeting on homeoprotein Six1.

scientific article

The CCCTC-binding factor (CTCF)-forkhead box protein M1 axis regulates tumour growth and metastasis in hepatocellular carcinoma.

scientific article published in September 2017

The significance of proline-rich tyrosine kinase2 (Pyk2) on hepatocellular carcinoma progression and recurrence.

scientific article published on 5 June 2007

Tie-2 regulates the stemness and metastatic properties of prostate cancer cells.

scientific article published on 29 April 2015

Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition.

scientific article published on September 2006

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