Search filters

List of works by Clara Bik-San Lau

A Natural Flavone Tricin from Grains Can Alleviate Tumor Growth and Lung Metastasis in Colorectal Tumor Mice

scientific article published on 15 August 2020

A bio-activity guided in vitro pharmacokinetic method to improve the quality control of Chinese medicines, application to Si Wu Tang.

scientific article published on 8 January 2011

A herbal formula containing roots of Salvia miltiorrhiza (Danshen) and Pueraria lobata (Gegen) inhibits inflammatory mediators in LPS-stimulated RAW 264.7 macrophages through inhibition of nuclear factor κB (NFκB) pathway.

scientific article

A polysaccharide extract from the medicinal plant Maidong inhibits the IKK-NF-κB pathway and IL-1β-induced islet inflammation and increases insulin secretion

scientific article published on 30 June 2020

A review on the immunomodulatory activity of Acanthopanax senticosus and its active components

scientific article published on 31 July 2019

A traditional Chinese formula composed of Chuanxiong Rhizoma and Gastrodiae Rhizoma (Da Chuanxiong Formula) suppresses inflammatory response in LPS -induced RAW 264.7 cells through inhibition of NF-κB pathway

scientific article

Actein Inhibits the Proliferation and Adhesion of Human Breast Cancer Cells and Suppresses Migration

scientific article published on 12 December 2018

An innovative anti-cancer Chinese herbal formula exhibited multi-targeted efficacies in metastatic breast cancer mouse model

article

An outcomes-based approach to curriculum development in pharmacy.

scientific article published on February 2009

Anti-Inflammatory Activities of Pentaherbs Formula, Berberine, Gallic Acid and Chlorogenic Acid in Atopic Dermatitis-Like Skin Inflammation

scientific article published on 20 April 2016

Anti-allergic drug discovery in China for eczema: current methods and future strategies.

scientific article published on 06 May 2013

Anti-angiogenesis and immunomodulatory activities of an anti-tumor sesquiterpene bigelovin isolated from Inula helianthus-aquatica

scientific article published on 24 November 2012

Anti-angiogenic activity of Erxian Decoction, a traditional Chinese herbal formula, in zebrafish.

scientific article published on 26 September 2012

Anti-angiogenic activity of Herba Epimedii on zebrafish embryos in vivo and HUVECs in vitro.

scientific article published on 12 November 2012

Anti-angiogenic effect and mechanism of rhein from Rhizoma Rhei.

scientific article

Anti-angiogenic effects and mechanisms of zerumin A from Alpinia caerulea

scientific article published on 25 October 2011

Anti-diabetic properties and phytochemistry of Momordica charantia L. (Cucurbitaceae) ⬇️

scientific article published on March 1, 1996

Anti-inflammatory and anti-allergic activities of Pentaherb formula, Moutan Cortex (Danpi) and gallic acid.

scientific article published on 25 February 2013

Anti-tumor and anti-osteolysis effects of the metronomic use of zoledronic acid in primary and metastatic breast cancer mouse models

scientific article published on 26 July 2013

Antiangiogenic effects and mechanisms of trans-ethyl p-methoxycinnamate from Kaempferia galanga L.

scientific article

Antidiabetic Effect of Schisandrae Chinensis Fructus Involves Inhibition of the Sodium Glucose Cotransporter.

scientific article

Antioxidant and antiangiogenic properties of phenolic extract from Pleurotus tuber-regium

scientific article published on 18 September 2014

Application of novel loop-mediated isothermal amplification (LAMP) for rapid authentication of the herbal tea ingredient Hedyotis diffusa Willd.

scientific article published on 24 May 2013

Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species.

scientific article published on 09 February 2017

Cerebral vasodilator properties of Danshen and Gegen: a study of their combined efficacy and mechanisms of actions

scientific article published on 2 November 2013

Characteristics of stem cells derived from rat fascia: in vitro proliferative and multilineage potential assessment.

scientific article published on 18 November 2014

Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin

scientific article published on 11 September 2014

Combined therapy using bevacizumab and turmeric ethanolic extract (with absorbable curcumin) exhibited beneficial efficacy in colon cancer mice

scientific article

Combined use of Andrographis paniculata and chemotherapeutics for metastatic oesophageal cancer: a pre-clinical study

scientific article published on 01 December 2019

Comparative studies of various ganoderma species and their different parts with regard to their antitumor and immunomodulating activities in vitro.

scientific article published on October 2006

Comparative studies on the immunomodulatory and antitumor activities of the different parts of fruiting body of Ganoderma lucidum and Ganoderma spores

scientific article published on 01 October 2008

Concise and Stereodivergent Synthesis of Carbasugars Reveals Unexpected Structure-Activity Relationship (SAR) of SGLT2 Inhibition

scientific article published on 17 July 2017

Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-κB signaling pathways.

scientific article published on 4 May 2015

Cytotoxic activities of Coriolus versicolor (Yunzhi) extract on human leukemia and lymphoma cells by induction of apoptosis.

scientific article published on July 2004

Danshen-Gegen decoction exerts proliferative effect on rat cardiac myoblasts H9c2 via MAPK and insulin pathways.

scientific article published on September 2011

Design, syntheses, and SAR studies of carbocyclic analogues of sergliflozin as potent sodium-dependent glucose cotransporter 2 inhibitors.

scientific article published on 19 June 2013

Desoxyrhaponticin (3,5-Dihydroxy-4'-methoxystilbene 3-O-beta-D-glucoside) Inhibits Glucose Uptake in the Intestine and Kidney: In Vitro and in Vivo Studies

scientific article published on 12 October 2006

Development of thermosensitive hydrogel containing methylene blue for topical antimicrobial photodynamic therapy

scientific article published on 07 January 2020

Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterning

scientific article published on 17 September 2013

Differential effect of Coriolus versicolor (Yunzhi) extract on cytokine production by murine lymphocytes in vitro.

scientific article published in November 2004

Dual-functional transdermal drug delivery system with controllable drug loading based on thermosensitive poloxamer hydrogel for atopic dermatitis treatment.

scientific article published on 19 April 2016

Echinacea purpurea (L.) Moench modulates human T-cell cytokine response.

scientific article

Effectiveness of Scutellaria barbata water extract on inhibiting colon tumor growth and metastasis in tumor-bearing mice

scientific article published on 01 September 2020

Effects of Gegen (Puerariae lobatae Radix) water extract on improving detrusor overactivity in spontaneously hypertensive rats

scientific article published on 24 March 2016

Efficacy and Durability in Direct Labeling of Mesenchymal Stem Cells Using Ultrasmall Superparamagnetic Iron Oxide Nanoparticles with Organosilica, Dextran, and PEG Coatings.

scientific article published on 7 April 2011

Elaborating the role of natural products on the regulation of autophagy and their potentials in breast cancer therapy

scientific article published on 30 March 2017

Enantiospecific Synthesis of Pseudoacarviosin as a Potential Antidiabetic Agent

scientific article published on 17 June 2008

Enhanced Transdermal Permeability via Constructing the Porous Structure of Poloxamer-Based Hydrogel.

scientific article

Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling

scientific article published on 14 October 2016

Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer.

scientific article published on 29 June 2017

Eriocalyxin B-induced apoptosis in pancreatic adenocarcinoma cells through thiol-containing antioxidant systems and downstream signalling pathways.

scientific article

Evaluation of the combined use of metronomic zoledronic acid and Coriolus versicolor in intratibial breast cancer mouse model

scientific article published on 12 April 2017

Evaluation of the safety profiles of estrogenic Chinese herbal medicines in breast cancer

scientific article published on 08 October 2018

Evaluation of widely consumed botanicals as immunological adjuvants

scientific article published on 18 July 2008

Extracts from Radix Astragali and Radix Rehmanniae promote keratinocyte proliferation by regulating expression of growth factor receptors.

scientific article published on 23 February 2012

Functional roles of eriocalyxin B in zebrafish revealed by transcriptome analysis

scientific article published on 01 June 2018

Gallic Acid Is the Major Active Component of Cortex Moutan in Inhibiting Immune Maturation of Human Monocyte-Derived Dendritic Cells

scientific article published on 10 September 2015

Gastrodia and Uncaria (tianma gouteng) water extract exerts antioxidative and antiapoptotic effects against cerebral ischemia in vitro and in vivo

scientific article

Gene expression profiling on the molecular action of danshen-gegen formula in a randomized placebo-controlled trial of postmenopausal women with hypercholesterolemia

scientific article published on 23 September 2013

Gene expression profiling reveals the plausible mechanisms underlying the antitumor and antimetastasis effects of Andrographis paniculata in esophageal cancer.

scientific article published on 26 March 2018

Green tea (Camellia sinensis) extract inhibits both the metastasis and osteolytic components of mammary cancer 4T1 lesions in mice.

scientific article

Herb-drug interaction between an anti-HIV Chinese herbal SH formula and atazanavir in vitro and in vivo.

scientific article published on 19 January 2015

Hypnotic effects of a novel anti-insomnia formula on Drosophila insomnia model.

scientific article published on 26 August 2014

Immunomodulatory and antitumour bioactive labdane diterpenoids from Leonurus japonicus

scientific article published on 05 August 2020

In vitro drug release and percutaneous behavior of poloxamer-based hydrogel formulation containing traditional Chinese medicine.

scientific article published on 23 September 2016

In vivo and in vitro anti-tumor and anti-metastasis effects of Coriolus versicolor aqueous extract on mouse mammary 4T1 carcinoma.

scientific article

Inhibition of intestinal and renal Na+-glucose cotransporter by naringenin.

scientific article

Inhibitory effect of different Dendrobium species on LPS-induced inflammation in macrophages via suppression of MAPK pathways

scientific article published on 01 July 2018

Inhibitory effects of Agaricus blazei extracts on human myeloid leukemia cells.

scientific article

Integrated Network Pharmacology Analysis and In Vitro Validation Revealed the Potential Active Components and Underlying Mechanistic Pathways of Herba Patriniae in Colorectal Cancer

Integrative Approach to Facilitate Fracture Healing: Topical Chinese Herbal Paste with Oral Strontium Ranelate.

scientific article published on 31 December 2017

Is Danggui Safe to be Taken by Breast Cancer Patients?-A Skepticism Finally Answered by Comprehensive Preclinical Evidence

scientific article published on 25 June 2019

Isodon eriocalyx and its bioactive component Eriocalyxin B enhance cytotoxic and apoptotic effects of gemcitabine in pancreatic cancer

scientific article published on 20 March 2018

Jaboticabin and Related Polyphenols from Jaboticaba ( Myrciaria cauliflora) with Anti-inflammatory Activity for Chronic Obstructive Pulmonary Disease

scientific article published on 24 January 2019

Mechanisms of the cerebral vasodilator actions of isoflavonoids of Gegen on rat isolated basilar artery

scientific article published on 20 November 2011

Mechanisms of the relaxant effect of a danshen and gegen formulation on rat isolated cerebral basilar artery.

scientific article published on 17 August 2010

Mechanistic studies on the antidiabetic activity of a polysaccharide-rich extract of Radix Ophiopogonis.

scientific article published on 11 May 2011

Melamine crystallization: physicochemical properties, interactions with other lithogenic salts and response to therapeutic agents

scientific article published on 17 February 2012

Melodinine V, an antitumor bisindole alkaloid with selective cytotoxicity from Melodinus henryi

scientific article published on 09 September 2016

Microencapsulation of Traditional Chinese Herbs-PentaHerbs extracts and potential application in healthcare textiles.

scientific article

Molecular angiogenic events of a two-herb wound healing formula involving MAPK and Akt signaling pathways in human vascular endothelial cells.

scientific article published on 11 June 2013

Molecular mechanisms of angiogenesis effect of active sub-fraction from root of Rehmannia glutinosa by zebrafish sprout angiogenesis-guided fractionation

scientific article published on 16 November 2013

Molecular studies of the congenital malformation induced by Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage ⬇️

scientific article published on August 19, 2012

Multiple modulatory activities of Andrographis paniculata on immune responses and xenograft growth in esophageal cancer preclinical models

scientific article published on 12 March 2019

Nanoparticle-encapsulated chlorhexidine against oral bacterial biofilms

scientific article published on 29 August 2014

Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/ STAT3 pathway.

scientific article published on 15 February 2018

Network pharmacology reveals potential functional components and underlying molecular mechanisms of Andrographis paniculata in esophageal cancer treatment

Neuroprotective effect of Da Chuanxiong Formula against cognitive and motor deficits in a rat controlled cortical impact model of traumatic brain injury.

scientific article published on 6 February 2018

New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment

scientific article published on 12 October 2016

Novel PI3K/AKT targeting anti-angiogenic activities of 4-vinylphenol, a new therapeutic potential of a well-known styrene metabolite

scientific article published on 8 June 2015

Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer

scientific article

Potent airway smooth muscle relaxant effect of cynatratoside B, a steroidal glycoside isolated from Cynanchum stauntonii.

scientific article published on 24 March 2014

Potential reproductive toxicity of Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage.

scientific article

Preclinical evaluations on the efficacy of a topical Chinese herbal formula for swelling control and pain relief.

scientific article

Preparation and characterisation of chitosan microcapsules loaded with Cortex Moutan.

scientific article published on 7 January 2013

Prospective self-controlled trial of the efficacy and tolerability of a herbal syrup for young children with eczema.

scientific article published on 6 February 2011

Quick identification of kuraridin, a noncytotoxic anti-MRSA (methicillin-resistant Staphylococcus aureus) agent from Sophora flavescens using high-speed counter-current chromatography.

scientific article

RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation.

scientific article

Review on phytotherapy in epilepsy.

scientific article

Rubinoboletus ballouii polysaccharides exhibited immunostimulatory activities through toll-like receptor-4 via NF-κB pathway

scientific article published on 18 November 2020

Schizonepeta tenuifolia: chemistry, pharmacology, and clinical applications.

scientific article

Screening and analysis of potential anti-tumor components from the stipe of Ganoderma sinense using high-performance liquid chromatography/time-of-flight mass spectrometry with multivariate statistical tool.

scientific article published on 22 January 2017

Screening for anti-inflammatory and bronchorelaxant activities of 12 commonly used Chinese herbal medicines.

scientific article

Selected Topical Agents Used in Traditional Chinese Medicine in the Treatment of Minor Injuries- A Review

scientific article

Seropharmacological study on osteogenic effects of post-absorption ingredients of an osteoprotective herbal formula.

scientific article published on 14 June 2016

Structural characterization and immunomodulatory effect of a polysaccharide HCP-2 from Houttuynia cordata.

scientific article

Synergistic Antibacterial Effects of Nanoparticles Encapsulated with Scutellaria baicalensis and Pure Chlorhexidine on Oral Bacterial Biofilms

scientific article

Synergistic effects of baicalein with ciprofloxacin against NorA over-expressed methicillin-resistant Staphylococcus aureus (MRSA) and inhibition of MRSA pyruvate kinase

Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase.

scientific article published on 27 March 2013

Synthesis and In Vitro Photodynamic Activity of Cationic Boron Dipyrromethene-Based Photosensitizers against Methicillin-Resistant Staphylococcus aureus

scientific article published on 29 May 2020

Synthesis of chiral hydroxylated enones as potential anti-tumor agents

scientific article published on 13 October 2012

TLR-4 may mediate signaling pathways of Astragalus polysaccharide RAP induced cytokine expression of RAW264.7 cells.

scientific article published on 29 December 2015

Ten years' research on a cardiovascular tonic: a comprehensive approach-from quality control and mechanisms of action to clinical trial

scientific article

The Aqueous Extract of Rhizome of Gastrodia elata Protected Drosophila and PC12 Cells against Beta-Amyloid-Induced Neurotoxicity.

scientific article published on 23 September 2013

The adjuvant value of Andrographis paniculata in metastatic esophageal cancer treatment - from preclinical perspectives.

scientific article published on 12 April 2017

The adjuvant value of Herba Cistanches when used in combination with statin in murine models.

scientific article published on 24 August 2017

The anti-hypertensive effect of Danshen (Salvia miltiorrhiza) and Gegen (Pueraria lobata) formula in rats and its underlying mechanisms of vasorelaxation

scientific article published on 09 August 2011

The antigluconeogenic activity of cucurbitacins from Momordica charantia

scientific article published on 11 March 2015

The aqueous extract of rhizome of Gastrodia elata Blume attenuates locomotor defect and inflammation after traumatic brain injury in rats.

scientific article published on 12 March 2016

The beneficial potential of polyphenol-enriched fraction from Erigerontis Herba on metabolic syndrome.

scientific article published on 25 April 2016

The combined use of Camellia sinensis and metronomic zoledronate in 4T1 mouse carcinoma against tumor growth and metastasis.

scientific article published on 20 May 2015

The combined use of Camellia sinensis and metronomic zoledronic acid in a breast cancer-induced osteolysis mouse model.

scientific article

The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.

scientific article

The known immunologically active components of Astragalus account for only a small proportion of the immunological adjuvant activity when combined with conjugate vaccines.

scientific article published on 02 December 2010

The natural agent 4-vinylphenol targets metastasis and stemness features in breast cancer stem-like cells

scientific article published on 18 May 2018

The protective effect of Herba Cistanches on statin-induced myotoxicity in vitro

scientific article published on 7 June 2016

The role of turmerones on curcumin transportation and P-glycoprotein activities in intestinal Caco-2 cells.

scientific article published on 19 December 2011

Transport in Caco-2 cell monolayers of antidiabetic cucurbitane triterpenoids from Momordica charantia fruits

scientific article published on 01 July 2014

Turmeric extract, with absorbable curcumin, has potent anti-metastatic effect in vitro and in vivo

scientific article published on 03 April 2018

Two immunosuppressive compounds from the mushroom Rubinoboletus ballouii using human peripheral blood mononuclear cells by bioactivity-guided fractionation.

scientific article published on 3 July 2013

Use of dong quai (Angelica sinensis) to treat peri- or postmenopausal symptoms in women with breast cancer: is it appropriate?

scientific article published on 8 November 2005

Using Ultra-Performance Liquid Chromatography Quadrupole Time of Flight Mass Spectrometry-Based Chemometrics for the Identification of Anti-angiogenic Biflavonoids from Edible Garcinia Species.

scientific article

Paulina is supported by:

About Paulina

Help