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List of works by Jérôme Leroy

Ca2+ currents in cardiac myocytes: Old story, new insights.

scientific article

Ca2+-sensitive regulation of E-type Ca2+ channel activity depends on an arginine-rich region in the cytosolic II-III loop.

scientific article published in August 2003

Caffeine-induced immobilization of gating charges in isolated guinea-pig ventricular heart cells.

scientific article published on February 2002

Calmodulin kinase II inhibition limits the pro-arrhythmic Ca2+ waves induced by cAMP-phosphodiesterase inhibitors.

scientific article

Catalytic enantioselective protonation of enol trifluoroacetates by means of hydrogenocarbonates and cinchona alkaloids

scientific article published on 08 July 2011

Compartmentation of cyclic nucleotide signaling in the heart: the role of cyclic nucleotide phosphodiesterases.

scientific article published on October 2006

Cyclic Adenosine Monophosphate Phosphodiesterase Type 4 Protects Against Atrial Arrhythmias

scientific article published on 01 June 2012

Cyclic nucleotide phosphodiesterases in heart and vessels: A therapeutic perspective.

scientific article published on 13 May 2016

Cyclic nucleotide phosphodiesterases: role in the heart and therapeutic perspectives

scientific article published on 4 November 2016

Determinants of the voltage dependence of G protein modulation within calcium channel beta subunits.

scientific article

Differential regulation of cardiac excitation-contraction coupling by cAMP phosphodiesterase subtypes.

scientific article published on 9 August 2013

Dominant-negative calcium channel suppression by truncated constructs involves a kinase implicated in the unfolded protein response.

scientific article

Imipramine as an alternative to formamide to detubulate rat ventricular cardiomyocytes

scientific article published on 06 June 2019

Interaction via a key tryptophan in the I-II linker of N-type calcium channels is required for beta1 but not for palmitoylated beta2, implicating an additional binding site in the regulation of channel voltage-dependent properties

scientific journal article

Interventricular differences in β-adrenergic responses in the canine heart: role of phosphodiesterases.

scientific article

PDEs create local domains of cAMP signaling.

scientific article published on 23 August 2011

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction.

scientific article published on 31 October 2016

Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases

scientific journal article

Standard and Strain Measurements by Echocardiography Detect Early Overloaded Right Ventricular Dysfunction: Validation against Hemodynamic and Myocyte Contractility Changes in a Large Animal Model.

scientific article published on 29 August 2017

The HOOK-domain between the SH3 and the GK domains of Cavbeta subunits contains key determinants controlling calcium channel inactivation.

scientific article

The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes

scientific article published on 28 June 2007

The cytosolic II-III loop of Cav2.3 provides an essential determinant for the phorbol ester-mediated stimulation of E-type Ca2+ channel activity.

scientific article published on May 2004

The molecular chaperone hsp70 interacts with the cytosolic II-III loop of the Cav2.3 E-type voltage-gated Ca2+ channel.

scientific article published on 14 March 2006

The stargazin-related protein gamma 7 interacts with the mRNA-binding protein heterogeneous nuclear ribonucleoprotein A2 and regulates the stability of specific mRNAs, including CaV2.2.

scientific article published on October 2008

[Role of cyclic nucleotide phosphodiesterases in the cAMP compartmentation in cardiac cells]

scientific article published on 03 April 2012

[Role of cyclic nucleotide phosphodiesterases type 3 and 4 in cardiac excitation-contraction coupling and arrhythmias]

scientific article published on 01 June 2013

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