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List of works by P Trayhurn

1,25-Dihydroxyvitamin D3 inhibits the cytokine-induced secretion of MCP-1 and reduces monocyte recruitment by human preadipocytes.

scientific article

11-Hydroxy-β-steroid dehydrogenase gene expression in canine adipose tissue and adipocytes: stimulation by lipopolysaccharide and tumor necrosis factor α.

scientific article published on 8 July 2011

A basic scientist's odyssey in nutrition

scientific article published on 21 March 2018

A defective response to cold in the obese (obob) mouse and the obese Zucker (fafa) rat [proceedings]

scientific article published on December 1, 1976

A microarray analysis of the hypoxia-induced modulation of gene expression in human adipocytes.

scientific article published on 21 February 2012

Acute and prolonged effects of TNF-alpha on the expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture

scientific article published on 04 April 2006

Adaptive changes in the concentration of the mitochondrial ‘uncoupling’ protein in brown adipose tissue of hamsters acclimated at different temperatures ⬇️

scientific article published on 01 December 1983

Adipocyte biology.

scientific article published on March 2007

Adipokine expression and secretion by canine adipocytes: stimulation of inflammatory adipokine production by LPS and TNFalpha.

scientific article published on 15 May 2010

Adipokine gene expression in dog adipose tissues and dog white adipocytes differentiated in primary culture

scientific article published on 01 August 2005

Adipose atrophy in cancer cachexia: morphologic and molecular analysis of adipose tissue in tumour-bearing mice

scientific article published on 3 October 2006

Adipose tissue and adipokines--energy regulation from the human perspective.

scientific article published on July 2006

Adipose tissue in obesity--an inflammatory issue

scientific article published on 01 March 2005

Adipose tissue-derived adiponectin expression is significantly associated with increased post operative mortality in horses undergoing emergency abdominal surgery

scientific article published on 01 August 2011

Adipose tissue. Editorial

scientific article published on 11 February 2011

Aerobic metabolism in the bovine lens ⬇️

scientific article published on 01 November 1971

An explanation for the elevated efficiency of the genetically obese (obob) mouse

scientific article published on 01 September 1978

An immunohistochemical and in situ hybridisation study of the postnatal development of uncoupling protein-1 and uncoupling protein-1 mRNA in lamb perirenal adipose tissue.

scientific article published in December 1998

An integrated view of the metabolic and genetic basis for obesity ⬇️

scientific article published on October 9, 1976

Appetite and energy balance signals from adipocytes.

scientific article

Asparagine metabolism in the bovine lens: A comparison with the metabolism of aspartic acid ⬇️

scientific article published on February 1, 1975

Biology of leptin--its implications and consequences for the treatment of obesity

scientific article published on 01 May 2001

Brown Adipose Tissue-A Therapeutic Target in Obesity?

scientific article published on 23 November 2018

Brown adipose tissue thermogenesis is ‘suppressed’ during lactation in mice ⬇️

scientific article published on July 1, 1982

Brown fat - hotting up again

scientific article published on 22 June 2009

Changes in insulin-receptor mRNA levels in skeletal muscle and brown adipose tissue of weanling rats during fasting and refeeding

scientific article published on November 1, 1992

Circulating Levels of the Adipokines Monocyte Chemotactic Protein-4 (MCP-4), Macrophage Inflammatory Protein-1β (MIP-1β), and Eotaxin-3 in Severe Obesity and Following Bariatric Surgery.

scientific article published on 14 June 2016

Circulating leptin during ovine pregnancy in relation to maternal nutrition, body composition and pregnancy outcome

scientific article published on 01 June 2001

Circulating leptin in women: a longitudinal study in the menstrual cycle and during pregnancy ⬇️

scientific article published on 01 July 1997

Circulating nerve growth factor levels in relation to obesity and the metabolic syndrome in women

scientific article published on 01 September 2007

Comment on: Hosagai et al. (2007) Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation: Diabetes 56:901-911

scientific article published on 01 September 2007

Contrasts between the effects of zinc-α2-glycoprotein, a putative β3/2-adrenoceptor agonist and the β3/2-adrenoceptor agonist BRL35135 in C57Bl/6 (ob/ob) mice.

scientific article

Costs of maintenance and growth in genetically obese (obob) mice

scientific article published on December 1, 1977

Detection of thermogenesis in rodents in response to anti-obesity drugs and genetic modification.

scientific article published on 8 April 2013

Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes

scientific article

Effect of acclimation temperature on the concentration of the mitochondrial ‘uncoupling’ protein measured by radioimmunoassay in mouse brown adipose tissue ⬇️

scientific article published on 01 September 1983

Effect of salicylate on the expression of adipokines and glucose transporters in human adipocytes is modulated by hypoxia.

scientific article published on 2 April 2009

Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (ob/ob) mice ⬇️

scientific article published on July 24, 1995

Endocrine and signalling role of adipose tissue: new perspectives on fat.

scientific article

Endotoxaemia leads to major increases in inflammatory adipokine gene expression in white adipose tissue of mice.

scientific article

Enhanced ZAG production by subcutaneous adipose tissue is linked to weight loss in gastrointestinal cancer patients

scientific article

Evidence that the hypothermic response of mice to Δ9-tetrahydrocannabinol is not mediated by changes in thermogenesis in brown adipose tissue ⬇️

scientific article published on 01 June 1991

Expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture: integrated response to TNF-alpha

scientific article published on 23 November 2004

Fatty Acids and Hypoxia Stimulate the Expression and Secretion of the Adipokine ANGPTL4 (Angiopoietin-Like Protein 4/ Fasting-Induced Adipose Factor) by Human Adipocytes ⬇️

scientific article published on June 28, 2011

Fatty acid synthesis in mouse brown adipose tissue the influence of environmental temperature on the proportion of whole-body fatty acid synthesis in brown adipose tissue and the liver ⬇️

scientific article published on June 23, 1981

Fatty acid synthesis in vivo in brown adipose tissue, liver and white adipose tissue of the cold-acclimated rat ⬇️

scientific article published on 01 August 1979

Functional body composition and related aspects in research on obesity and cachexia: report on the 12th Stock Conference held on 6 and 7 September 2013 in Hamburg, Germany

scientific article

GDP binding to brown-adipose-tissue mitochondria of diabetic-obese (db/db) mice. Decreased binding in both the obese and pre-obese states ⬇️

scientific article published on March 15, 1981

GDP binding to brown-adipose-tissue mitochondria of mice treated chronically with corticosterone ⬇️

scientific article published on July 15, 1983

Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins.

scientific article

HIF-1alpha protein rather than mRNA as a marker of hypoxia in adipose tissue in obesity: focus on "inflammation is associated with a decrease of lipogenic factors in omental fat in women," by Poulain-Godefroy et al

scientific article published on 01 October 2008

Hormonal and neuroendocrine regulation of energy balance--the role of leptin.

scientific article

Hyperleptinaemia in mice induced by administration of the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine.

scientific article

Hyperleptinaemia precedes hyperinsulinaemia in Zucker (fa/fa) rats ⬇️

scientific article published on May 1, 1998

Hypoxia and adipocyte physiology: implications for adipose tissue dysfunction in obesity.

scientific article published on May 2014

Hypoxia and adipose tissue function and dysfunction in obesity.

scientific article published on January 2013

Hypoxia and the endocrine and signalling role of white adipose tissue

scientific article published on 01 October 2008

Hypoxia induces leptin gene expression and secretion in human preadipocytes: differential effects of hypoxia on adipokine expression by preadipocytes.

scientific article published on 7 May 2008

IL-1β (interleukin-1β) stimulates the production and release of multiple cytokines and chemokines by human preadipocytes

scientific article published on 18 February 2016

IL-1β and TNFα inhibit GPR120 (FFAR4) and stimulate GPR84 (EX33) and GPR41 (FFAR3) fatty acid receptor expression in human adipocytes: implications for the anti-inflammatory action of n-3 fatty acids

scientific article published on 24 August 2017

IL-33 stimulates expression of the GPR84 (EX33) fatty acid receptor gene and of cytokine and chemokine genes in human adipocytes

scientific article published on 16 May 2018

IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes.

scientific article published on 23 April 2009

Identification of brown fat and mechanisms for energy balance in the marsupial, Sminthopsis crassicaudata ⬇️

scientific article published on July 1, 1997

Immunological identification of uncoupling protein in interscapular “brown” adipose tissue of suckling and adult pipistrelle bats (Pipistrellus pipistrellus) ⬇️

scientific article published on 01 January 1991

Improvement in insulin resistance and reduction in plasma inflammatory adipokines after weight loss in obese dogs.

scientific article published on 5 August 2009

Increased proton conductance pathway in brown adipose tissue mitochondria of rats exhibiting diet-induced thermogenesis ⬇️

scientific article published on July 17, 1980

Induction of uncoupling protein-2 (UCP2) gene expression on the differentiation of rat preadipocytes to adipocytes in primary culture

scientific article published on 01 February 1999

Inflammatory gene expression patterns revealed by DNA microarray analysis in TNF-alpha-treated SGBS human adipocytes.

scientific article published on October 2006

Inhibition by insulin of resistin gene expression in 3T3‐L1 adipocytes ⬇️

scientific article published on October 19, 2001

Is the “mammalian” brown fat-specific mitochondrial uncoupling protein present in adipose tissues of birds? ⬇️

scientific article published on 01 January 1991

Lactate and the GPR81 receptor in metabolic regulation: implications for adipose tissue function and fatty acid utilisation by muscle during exercise ⬇️

scientific article published on 09 September 2011

Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta ⬇️

scientific article published on September 30, 1997

Leptin and reproduction

scientific article published on 01 August 1998

Leptin resistance in obese humans: does it exist and what does it mean?

scientific article published on 01 December 1998

Leptin--a critical body weight signal and a "master" hormone?

scientific article

Leptin: fundamental aspects

scientific article published on 01 February 1999

Licence to publish--authors in the British Journal of Nutrition now retain the copyright of their material

scientific article published on 01 July 2000

Lipopolysaccharide induces a downregulation of adiponectin receptors in-vitro and in-vivo

scientific article

Macrophage-secreted factors inhibit ZAG expression and secretion by human adipocytes

scientific article published on 08 June 2010

Metallothionein gene expression in human adipose tissue from lean and obese subjects.

scientific article

Michael J Stock (1942-2001): an appreciation

scientific article published on 01 September 2001

Microarray analysis identifies matrix metalloproteinases (MMPs) as key genes whose expression is up-regulated in human adipocytes by macrophage-conditioned medium

scientific article published on 09 July 2009

Mining microarray datasets in nutrition: expression of the GPR120 (n-3 fatty acid receptor/sensor) gene is down-regulated in human adipocytes by macrophage secretions.

scientific article published on 12 June 2012

Modulation of adipokine production, glucose uptake and lactate release in human adipocytes by small changes in oxygen tension

scientific article published on 23 June 2011

Molecular biology and nutrition: the quest for integration

scientific article published on 01 October 1998

NGF gene expression and secretion by canine adipocytes in primary culture: upregulation by the inflammatory mediators LPS and TNFalpha.

scientific article

NGF gene expression and secretion in white adipose tissue: regulation in 3T3-L1 adipocytes by hormones and inflammatory cytokines

scientific journal article

Neutral proteinase activity in the human lens ⬇️

scientific article published on March 1, 1976

New Physiological Aspects of Brown Adipose Tissue

scientific article published on 01 December 2014

Nutritional genomics - "Nutrigenomics"

Obesity -- what role now for nutritional science?

scientific article published on 01 January 2005

Obesity and hyperleptinemia in metallothionein (-I and -II) null mice ⬇️

scientific article published on January 6, 1998

Obesity in the Inuit - Adipose tissue and ischaemic heart desease

scientific article published in October 2009

Obesity in the Inuit--adipose tissue and ischaemic heart disease

scientific article published on 01 December 2009

Obesity, its associated disorders and the role of inflammatory adipokines in companion animals.

scientific article published on 15 May 2010

Of genes and genomes - and dark matter

scientific article published on 01 January 2004

Ontogenic loss of brown adipose tissue sensitivity to beta-adrenergic stimulation in the ovine.

scientific article published on 5 October 2006

Open Access publishing: the continuing development of the Journal of Nutritional Science.

scientific article published on 12 January 2018

Origins and early development of the concept that brown adipose tissue thermogenesis is linked to energy balance and obesity

scientific article

Oxygen - the forgotten nutrient.

scientific article published on 4 September 2017

Oxygen deprivation and the cellular response to hypoxia in adipocytes - perspectives on white and brown adipose tissues in obesity

scientific article

Oxygen-A Critical, but Overlooked, Nutrient

scientific article published on 12 February 2019

PCR array and protein array studies demonstrate that IL-1β (interleukin-1β) stimulates the expression and secretion of multiple cytokines and chemokines in human adipocytes.

scientific article published on 15 October 2015

PCR arrays indicate that the expression of extracellular matrix and cell adhesion genes in human adipocytes is regulated by IL-1β (interleukin-1β).

scientific article published on 18 November 2016

Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ.

scientific article

Postnatal development of the ob gene system: elevated leptin levels in suckling fa/fa rats ⬇️

scientific article published on July 1, 1997

Postnatal expression of zinc-alpha2-glycoprotein in rat white and brown adipose tissue.

scientific article

Prakash Sarvotham Shetty (1943–2018)

Proteolysis of lens proteins (autolysis)

scientific article published on June 1, 1976

Rapid chemiluminescent detection of mRNAs on Northern blots with digoxigenin end‐labelled oligonucleotides ⬇️

scientific article published on 01 March 1995

Recent highly cited articles in the British Journal of Nutrition (including Supplements): An update

scientific article published on 01 July 2004

Recruiting Brown Adipose Tissue in Human Obesity

scientific article published on 01 May 2016

Regulation of adipose tissue metabolism in cancer cachexia.

scientific article published on May 2008

Regulation of angiopoietin-like protein 4/fasting-induced adipose factor (Angptl4/FIAF) expression in mouse white adipose tissue and 3T3-L1 adipocytes.

scientific article published on 17 December 2007

Regulation of haptoglobin gene expression in 3T3-L1 adipocytes by cytokines, catecholamines, and PPARgamma.

scientific article published on January 2004

Regulation of leptin production: a dominant role for the sympathetic nervous system?

scientific article published on 01 August 1998

Regulation of leptin production: sympathetic nervous system interactions.

scientific article

Resistin and RELM-alpha gene expression in white adipose tissue of lactating mice

scientific article published on 01 August 2002

Rhythmic diurnal gene expression in human adipose tissue from individuals who are lean, overweight, and type 2 diabetic.

scientific article published on 16 March 2011

Role of hypothalamic neuropeptide Y neurons in the defective thermogenic response to acute cold exposure in fatty Zucker rats ⬇️

scientific article published on September 1, 1997

Secreted proteins from adipose tissue and skeletal muscle – adipokines, myokines and adipose/muscle cross-talk ⬇️

scientific article published on December 15, 2010

Semaphorin 3C is a novel adipokine linked to extracellular matrix composition.

scientific article published on 12 May 2013

Stimulation of NGF expression and secretion in 3T3-L1 adipocytes by prostaglandins PGD2, PGJ2, and Delta12-PGJ2.

scientific article published on 15 February 2005

Stimulation of inflammatory gene expression in human preadipocytes by macrophage-conditioned medium: upregulation of IL-6 production by macrophage-derived IL-1β.

scientific article

Studies on the body composition, fat distribution and fat cell size and number of 'Ad', a new obese mutant mouse

scientific article published on January 1, 1979

Suppression of leptin during lactation: contribution of the suckling stimulus versus milk production

scientific article published on 01 June 1999

Tempus fugit--evolution and current impact of the British Journal of Nutrition

scientific article published on 01 September 2005

The Nutrition Society journals: vive la différence!

scientific article published on August 2016

The Nutrition Society journals: vive la différence!

scientific article

The adipokine zinc-α2-glycoprotein (ZAG) is downregulated with fat mass expansion in obesity

scientific article published on 22 June 2009

The adipokine zinc-α2-glycoprotein activates AMP kinase in human primary skeletal muscle cells

scientific article published on 01 May 2011

The biology of obesity.

scientific article published in February 2005

The development of obesity in preweaning obob mice

scientific article published on 01 March 1978

The effect of trypsin on retinal rod outer segments: Trypsin digestion as a means of isolating viable discs ⬇️

scientific article published on 01 May 1975

The metabolism of amino acids in the bovine lens. Their oxidation as a source of energy ⬇️

scientific article published on September 1, 1973

The pro-inflammatory cytokine IL-18 is expressed in human adipose tissue and strongly upregulated by TNFalpha in human adipocytes

scientific article published on 21 September 2005

The public library of science and "open access" to the scientific literature

scientific article published on 01 January 2002

The rapid determination of carcass fat by the Foss-Let specific gravity technique

scientific article published on 01 November 1976

The role of thermoregulatory thermogenesis in the development of obesity in genetically-obese (ob/ob) mice pair-fed with lean siblings

scientific article published on November 1, 1979

Thermogenic defect in pre-obese ob/ob mice

scientific article published on March 3, 1977

Thermoregulation and non-shivering thermogenesis in the genetically obese (ob/ob) mouse

scientific article published on February 22, 1978

Thermoregulation in the diabetic-obese (db/db) mouse. The role of non-shivering thermogenesis in energy balance

scientific article published on 01 July 1979

Tim Bartness, Ph.D. (1953-2015).

scientific article published on January 2016

Types I and II iodothyronine 5'-deiodinase activities in perirenal brown adipose tissue of neonatal goats

scientific article published on 01 November 1992

Upregulation of the expression of inflammatory and angiogenic markers in human adipocytes by a synthetic cannabinoid, JTE-907.

scientific article published on 5 July 2010

Vitamin D signalling in adipose tissue.

scientific article published on 09 October 2012

White adipose tissue grafts--keeping in contact

scientific article published on 01 August 2005

Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed and secreted by human (SGBS) adipocytes.

scientific article published in January 2005

Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia.

scientific article

Zinc-α2-glycoprotein: an adipokine modulator of body fat mass?

scientific article published on June 2010

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