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List of works by Saskia C A de Jager

A Pro-Inflammatory Biomarker-Profile Predicts Amputation-Free Survival in Patients with Severe Limb Ischemia

scientific article published on 24 July 2019

Akt2/LDLr double knockout mice display impaired glucose tolerance and develop more complex atherosclerotic plaques than LDLr knockout mice.

scientific article published on 12 November 2013

An unexpected intriguing effect of Toll-like receptor regulator RP105 (CD180) on atherosclerosis formation with alterations on B-cell activation.

scientific article

Atheroprotective properties of human Omentin-1 in experimental atherosclerosis

scientific article published on 02 March 2016

BLT1 antagonist LSN2792613 reduces infarct size in a mouse model of myocardial ischaemia-reperfusion injury

scientific article published on 8 October 2015

CCL3 (MIP-1 alpha) levels are elevated during acute coronary syndromes and show strong prognostic power for future ischemic events

scientific article

CXCR3 antagonist NBI-74330 attenuates atherosclerotic plaque formation in LDL receptor-deficient mice

scientific article published on 29 November 2007

Chemokines and atherosclerotic plaque progression: towards therapeutic targeting?

scientific article published on January 2007

Circulating CD14+CD16- classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients

scientific article published on 07 January 2019

Circulating GDF-15 levels predict future secondary manifestations of cardiovascular disease explicitly in women but not men with atherosclerosis

scientific article published on 22 March 2017

Circulating immunoglobulins are not associated with intraplaque mast cell number and other vulnerable plaque characteristics in patients with carotid artery stenosis

scientific article

Crosstalk of lipids and inflammation in atherosclerosis: the PRO of PGRN? ⬇️

scientific article published on August 14, 2013

Elevated mean neutrophil volume represents altered neutrophil composition and reflects damage after myocardial infarction

scientific article

Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes

scientific article

Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration

scientific article published on February 2014

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

scientific article published on 07 November 2019

Genetic variation within the Y chromosome is not associated with histological characteristics of the atherosclerotic carotid artery or aneurysmal wall

scientific article

Growth Differentiation Factor 15 Is Associated With Major Amputation and Mortality in Patients With Peripheral Artery Disease

scientific article published on 30 August 2017

Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages.

scientific article published on 23 February 2016

Hematopoietic G‐protein‐coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor‐knockout mice ⬇️

scientific article published on October 9, 2012

High Levels of (Un)Switched Memory B Cells Are Associated With Better Outcome in Patients With Advanced Atherosclerotic Disease

scientific article published on 7 September 2017

Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype

scientific article

Immunomodulation in Heart Failure with Preserved Ejection Fraction: Current State and Future Perspectives

scientific article published on 22 May 2020

Impaired kidney function is associated with intraplaque hemorrhage in patients undergoing carotid endarterectomy

scientific article published on 22 September 2017

Increased circulating IgG levels, myocardial immune cells and IgG deposits support a role for an immune response in pre- and end-stage heart failure

scientific article published on 26 September 2019

Leukocyte-Specific CCL3 Deficiency Inhibits Atherosclerotic Lesion Development by Affecting Neutrophil Accumulation ⬇️

scientific article published on January 3, 2013

Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation.

scientific article

Mesenchymal stem cell therapy for cardiac inflammation: immunomodulatory properties and the influence of toll-like receptors.

scientific article published on 10 December 2013

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

scientific article published on 28 September 2020

Mutation in KERA identified by linkage analysis and targeted resequencing in a pedigree with premature atherosclerosis

scientific article

Noncanonical NF-κB signaling in microvessels of atherosclerotic lesions is associated with inflammation, atheromatous plaque morphology and myocardial infarction

scientific article published on 29 January 2018

Oxidized low-density lipoprotein-induced apoptotic dendritic cells as a novel therapy for atherosclerosis

scientific article published on 4 February 2015

Perivascular Mast Cells Promote Atherogenesis and Induce Plaque Destabilization in Apolipoprotein E–Deficient Mice

scientific article published on 30 April 2007

Platelet RNA modules point to coronary calcification in asymptomatic women with former preeclampsia

scientific article published on 11 October 2019

Potential of mesenchymal- and cardiac progenitor cells for therapeutic targeting of B-cells and antibody responses in end-stage heart failure

scientific article published on 31 December 2019

Requirements for Proper Immunosuppressive Regimens to Limit Translational Failure of Cardiac Cell Therapy in Preclinical Large Animal Models

scientific article published on 31 May 2020

Serine protease inhibitor Serp-1 strongly impairs atherosclerotic lesion formation and induces a stable plaque phenotype in ApoE-/-mice.

scientific article published on 14 August 2003

Short Communication: The Neuropeptide Substance P Mediates Adventitial Mast Cell Activation and Induces Intraplaque Hemorrhage in Advanced Atherosclerosis

scientific article published on 19 November 2009

Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure

scientific article published on 28 December 2018

Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions

Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets.

scientific article published in August 2017

Systemic MCP1/CCR2 blockade and leukocyte specific MCP1/CCR2 inhibition affect aortic aneurysm formation differently

scientific article published on 07 February 2010

TLR accessory molecule RP105 (CD180) is involved in post-interventional vascular remodeling and soluble RP105 modulates neointima formation

scientific article

Vaccination strategies in atherosclerosis.

scientific article published on 20 October 2011

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