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List of works by María Isabel Garcia Moreno

6-Amino-6-deoxy-5,6-di-N-(N'-octyliminomethylidene)nojirimycin: synthesis, biological evaluation, and crystal structure in complex with acid beta-glucosidase

scientific article

A bicyclic 1-deoxygalactonojirimycin derivative as a novel pharmacological chaperone for GM1 gangliosidosis.

scientific article published on 22 January 2013

Amphiphilic 1-Deoxynojirimycin Derivatives through Click Strategies for Chemical Chaperoning in N370S Gaucher Cells

scientific article published on 29 August 2011

Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: Effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidase ⬇️

scientific article published on March 30, 2011

Bicyclic derivatives of L-idonojirimycin as pharmacological chaperones for neuronopathic forms of Gaucher disease.

scientific article published on 18 April 2013

Castanospermine-trehazolin hybrids: a new family of glycomimetics with tuneable glycosidase inhibitory properties.

scientific article

Fluorescent-tagged sp2-iminosugars with potent β-glucosidase inhibitory activity.

scientific article published on 7 September 2010

Fluorinated Chaperone-β-Cyclodextrin Formulations for β-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease.

scientific article published on 7 February 2017

Generalized Anomeric Effect in Action: Synthesis and Evaluation of Stable Reducing Indolizidine Glycomimetics as Glycosidase Inhibitors

article

Generalized Anomeric Effect ingem-Diamines: Stereoselective Synthesis of α-N-Linked Disaccharide Mimics

scientific article published on 01 August 2009

Giant Glycosidase Inhibitors: First- and Second-Generation Fullerodendrimers with a Dense Iminosugar Shell.

scientific article published on 27 December 2017

Glycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoring

scientific article

Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp(2)-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts

scientific article published on 31 August 2015

Intramolecular Benzyl Protection Delivery:  A Practical Synthesis of DMDP and DGDP fromd-Fructose

scientific article published on 01 January 2006

Molecular basis for beta-glucosidase inhibition by ring-modified calystegine analogues

scientific article

Multivalent iminosugars to modulate affinity and selectivity for glycosidases.

scientific article

One-step synthesis of non-anomeric sugar isothiocyanates from sugar azides.

scientific article published in November 2002

Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition.

scientific article published on 4 July 2016

Rigid Spacer-Mediated Synthesis of Bis-Spiroketal Ring Systems:  Stereoselective Synthesis of Nonsymmetrical Spiro Disaccharides

scientific article published on 01 February 2005

Synthesis and biological evaluation of guanidine-type iminosugars.

scientific article

Synthesis of thiohydantoin-castanospermine glycomimetics as glycosidase inhibitors.

scientific article

Synthesis of β-galactosylamides as ligands of the peanut lectin. Insights into the recognition process.

scientific article published on 23 March 2017

Targeted delivery of pharmacological chaperones for Gaucher disease to macrophages by a mannosylated cyclodextrin carrier.

scientific article published in April 2014

The Impact of Heteromultivalency in Lectin Recognition and Glycosidase Inhibition: An Integrated Mechanistic Study

scientific article published on 27 February 2017

Topological effects and binding modes operating with multivalent iminosugar-based glycoclusters and mannosidases.

scientific article

Tuning glycosidase inhibition through aglycone interactions: pharmacological chaperones for Fabry disease and GM1 gangliosidosis

scientific article published on 23 May 2012

o-Xylylene protecting group in carbohydrate chemistry: application to the regioselective protection of a single vic-diol segment in cyclodextrins.

scientific article published on 4 February 2013

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