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List of works by Paul R Gilson

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Comparative genomics of the neglected human malaria parasite Plasmodium vivax

scientific article
A newly discovered protein export machine in malaria parasites

scientific article
An aspartyl protease directs malaria effector proteins to the host cell

scientific article
Distinct protein classes including novel merozoite surface antigens in Raft-like membranes of Plasmodium falciparum

scientific article (publication date: 2 December 2005)
Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker development

scientific article published on 17 June 2013
Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of the human malaria parasite Plasmodium falciparum

scientific article (publication date: July 2006)
PTEX is an essential nexus for protein export in malaria parasites

scientific article (publication date: 31 July 2014)
Potential epigenetic regulatory proteins localise to distinct nuclear sub-compartments in Plasmodium falciparum

scientific article (publication date: 2010)
Revealing the sequence and resulting cellular morphology of receptor-ligand interactions during Plasmodium falciparum invasion of erythrocytes

scientific article (publication date: February 2015)
Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites

scientific article
Biosynthesis, localization, and macromolecular arrangement of the Plasmodium falciparum translocon of exported proteins (PTEX)

scientific article (publication date: 9 March 2012)
A novel family of Apicomplexan glideosome-associated proteins with an inner membrane-anchoring role

scientific article (publication date: 11 September 2009)
Protein kinase a dependent phosphorylation of apical membrane antigen 1 plays an important role in erythrocyte invasion by the malaria parasite

scientific article
A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression

scientific article
The Plasmodium translocon of exported proteins (PTEX) component thioredoxin-2 is important for maintaining normal blood-stage growth

scientific article (publication date: September 2013)
Tetracycline analogue-regulated transgene expression in Plasmodium falciparum blood stages using Toxoplasma gondii transactivators

scientific article
Plasmodium falciparum-encoded exported hsp70/hsp40 chaperone/co-chaperone complexes within the host erythrocyte

scientific article (publication date: November 2012)
Spatial association with PTEX complexes defines regions for effector export into Plasmodium falciparum-infected erythrocytes

scientific article
Advances in molecular genetic systems in malaria

scientific article published on June 2015
Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte

scholarly article by Danushka S Marapana et al published September 2018 in Nature Microbiology
Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

scientific article (publication date: 2 March 2017)
Identification of protein complexes in detergent-resistant membranes of Plasmodium falciparum schizonts

scientific article published on 27 April 2007
Biochemical and functional analysis of two Plasmodium falciparum blood-stage 6-cys proteins: P12 and P41

scientific article
Conditional expression of apical membrane antigen 1 in Plasmodium falciparum shows it is required for erythrocyte invasion by merozoites

scientific article (publication date: May 2014)
A model for the progression of receptor–ligand interactions during erythrocyte invasion by Plasmodium falciparum

scientific article published on March 21, 2012
Quantifying the importance of MSP1-19 as a target of growth-inhibitory and protective antibodies against Plasmodium falciparum in humans

scientific article
Overlaying Molecular and Temporal Aspects of Malaria Parasite Invasion

scientific article published on January 7, 2016
Recruitment of Factor H as a Novel Complement Evasion Strategy for Blood-Stage Plasmodium falciparum Infection

scientific article (publication date: February 2016)
Systematic analysis of FKBP inducible degradation domain tagging strategies for the human malaria parasite Plasmodium falciparum

scientific article
Insights and controversies into the role of the key apicomplexan invasion ligand, Apical Membrane Antigen 1.

scientific article
Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum

scientific article
Proteomic analysis reveals novel proteins associated with the Plasmodium protein exporter PTEX and a loss of complex stability upon truncation of the core PTEX component, PTEX150

scientific article (publication date: November 2016)
Molecular genetic tools in Toxoplasma and Plasmodium: achievements and future needs

scientific article published on August 2007
Plasmodium falciparum transfected with ultra bright NanoLuc luciferase offers high sensitivity detection for the screening of growth and cellular trafficking inhibitors

scientific article
Characterisation of complexes formed by parasite proteins exported into the host cell compartment of Plasmodium falciparum infected red blood cells.

scientific article
MSP1(19) miniproteins can serve as targets for invasion inhibitory antibodies in Plasmodium falciparum provided they contain the correct domains for cell surface trafficking

scientific article published in April 2008
Plasmodium falciparum Adhesins Play an Essential Role in Signalling and Activation of Invasion into Human Erythrocytes

scientific article
Protein export in malaria parasites: an update

scientific article published on January 27, 2014
Differing rates of antibody acquisition to merozoite antigens in malaria: implications for immunity and surveillance

scientific article published on 11 November 2016
Inhibition of malaria parasite development by a cyclic peptide that targets the vital parasite protein SERA5.

scientific article
Protein export in Plasmodium parasites: from the endoplasmic reticulum to the vacuolar export machine

scientific article published on 17 February 2010
The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites

scientific article published on 21 July 2017
Trafficking of the exported P. falciparum chaperone PfHsp70x

scientific article (publication date: 8 November 2016)
Hierarchical phosphorylation of apical membrane antigen 1 is required for efficient red blood cell invasion by malaria parasites

scientific article
Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity

scientific article published on 12 January 2017
Host cell remodelling in malaria parasites: a new pool of potential drug targets

scientific article published on 28 June 2016
Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum

scientific article (publication date: 22 November 2016)
Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria

scientific article published on 30 October 2017
Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon

scientific article
Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation

scientific article published on 22 April 2016

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