List of works - Sascha Gutmann

A new aspect of specific radiation damage: hydrogen abstraction from organic molecules

scientific article published on 25 February 2009

A simple protocol for amino acid type selective isotope labeling in insect cells with improved yields and high reproducibility

scientific article published on 02 October 2011

BMX and its role in inflammation, cardiovascular disease, and cancer.

scientific article published on April 2012

Crystal structure of the transfer-RNA domain of transfer-messenger RNA in complex with SmpB

scientific article

Design of Potent and Selective Covalent Inhibitors of Bruton's Tyrosine Kinase Targeting an Inactive Conformation

scientific article published on 06 September 2019

Dial tm for rescue: tmRNA engages ribosomes stalled on defective mRNAs

scientific article published on February 2004

Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors

scientific article published on 2 June 2016

Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors.

scientific article published on 25 August 2017

Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors

scientific article

Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase

scientific article published on 04 March 2020

Novel sample preparation technique for protein crystal X-ray crystallographic analysis combining microfluidics and acoustic manipulation

scientific article

Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor

scientific article published on 22 May 2015

Origin and temperature dependence of radiation damage in biological samples at cryogenic temperatures

scientific article

PAX8 and MECOM are interaction partners driving ovarian cancer

scientific article

Strategies for single particle manipulation using acoustic and flow fields

scientific article published on 23 September 2009

Structural basis of enzyme encapsulation into a bacterial nanocompartment

scientific article

The Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold

scientific article published on 27 April 2015

The atomic structure of baculovirus polyhedra reveals the independent emergence of infectious crystals in DNA and RNA viruses

scientific article

The molecular organization of cypovirus polyhedra

scientific article

List of works by Sascha Gutmann

A new aspect of specific radiation damage: hydrogen abstraction from organic molecules

A simple protocol for amino acid type selective isotope labeling in insect cells with improved yields and high reproducibility

BMX and its role in inflammation, cardiovascular disease, and cancer.

Crystal structure of the transfer-RNA domain of transfer-messenger RNA in complex with SmpB

Design of Potent and Selective Covalent Inhibitors of Bruton's Tyrosine Kinase Targeting an Inactive Conformation

Dial tm for rescue: tmRNA engages ribosomes stalled on defective mRNAs

Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors

Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors.

Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors

Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase

Novel sample preparation technique for protein crystal X-ray crystallographic analysis combining microfluidics and acoustic manipulation

Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor

Origin and temperature dependence of radiation damage in biological samples at cryogenic temperatures

PAX8 and MECOM are interaction partners driving ovarian cancer

Strategies for single particle manipulation using acoustic and flow fields

Structural basis of enzyme encapsulation into a bacterial nanocompartment

The Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold

The atomic structure of baculovirus polyhedra reveals the independent emergence of infectious crystals in DNA and RNA viruses

The molecular organization of cypovirus polyhedra