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List of works by Lhousseine Touqui

A Crucial Role of Flagellin in the Induction of Airway Mucus Production by Pseudomonas aeruginosa ⬇️

scientific article published on July 2, 2012

A novel bacterial resistance mechanism against human group IIA-secreted phospholipase A2: role of Streptococcus pyogenes sortase A.

scientific article published on 9 November 2011

A role for 12R-lipoxygenase in MUC5AC expression by respiratory epithelial cells

scientific article

Anthrax lethal toxin down-regulates type-IIA secreted phospholipase A(2) expression through MAPK/NF-kappaB inactivation

scientific article published on 4 December 2009

Anthrax lethal toxin impairs IL-8 expression in epithelial cells through inhibition of histone H3 modification

scientific article

Arachidonic acid differentially affects basal and lipopolysaccharide-induced sPLA(2)-IIA expression in alveolar macrophages through NF-kappaB and PPAR-gamma-dependent pathways

scientific article

Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 pathways and not by the toll-like receptor-MyD88 pathway.

scientific article

Bacteria-driven peribronchial lymphoid neogenesis in bronchiectasis and cystic fibrosis

scientific article published on 26 April 2017

Bacteriophages can treat and prevent Pseudomonas aeruginosa lung infections

scientific article published in April 2010

Blood neutrophil bactericidal activity against methicillin-resistant and methicillin-sensitive Staphylococcus aureus during cardiac surgery

scientific article published in August 2005

CFTR dysfunction induces vascular endothelial growth factor synthesis in airway epithelium.

scientific article published on 21 March 2013

Correction: A Crucial Role of Flagellin in the Induction of Airway Mucus Production by Pseudomonas aeruginosa.

scientific article published on 9 August 2012

Cystic fibrosis transmembrane conductance regulator (CFTR) regulates the production of osteoprotegerin (OPG) and prostaglandin (PG) E2 in human bone.

scientific article published on 14 December 2009

Cytosolic phospholipase A2alpha mediates Pseudomonas aeruginosa LPS-induced airway constriction of CFTR -/- mice.

scientific article published on 29 April 2010

Cytosolic phospholipase A2α enhances mouse mortality induced by Pseudomonas aeruginosa pulmonary infection via interleukin 6.

scientific article published on 6 September 2014

Edema toxin impairs anthracidal phospholipase A2 expression by alveolar macrophages

scientific article

Effect of surfactant on pulmonary expression of type IIA PLA(2) in an animal model of acute lung injury

scientific article published in April 2002

Eicosanoid release is increased by membrane destabilization and CFTR inhibition in Calu-3 cells

scientific article

High bactericidal efficiency of type iia phospholipase A2 against Bacillus anthracis and inhibition of its secretion by the lethal toxin

scientific article

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

scientific article

Host-microbe interactions in distal airways: relevance to chronic airway diseases

scientific article

Immuno-modulatory functions of the type-3 secretion system and impacts on the pulmonary host defense: A role for ExoS of Pseudomonas aeruginosa in cystic fibrosis

scientific article published on 12 January 2018

Impact of CFTR DeltaF508 mutation on prostaglandin E2 production and type IIA phospholipase A2 expression by pulmonary epithelial cells

scientific article (publication date: November 2005)

Implications of oxidative stress in the cytotoxicity of Pseudomonas aeruginosa ExoU.

scientific article published on 16 September 2005

In vitro and in vivo evidence for an inflammatory role of the calcium channel TRPV4 in lung epithelium: Potential involvement in cystic fibrosis.

scientific article published on 5 August 2016

In vivo protective role of human group IIa phospholipase A2 against experimental anthrax

scientific article published in November 2005

Influenza A induces the major secreted airway mucin MUC5AC in a protease-EGFR-extracellular regulated kinase-Sp1-dependent pathway.

scientific article

Inhibitory effects of surfactant protein A on surfactant phospholipid hydrolysis by secreted phospholipases A2.

scientific article published in July 2003

Interaction of secreted phospholipase A2 and pulmonary surfactant and its pathophysiological relevance in acute respiratory distress syndrome.

scientific article published on December 2003

Lipid body mobilization in the ExoU-induced release of inflammatory mediators by airway epithelial cells

scientific article

Lung protease/anti-protease network and modulation of mucus production and surfactant activity.

scientific article published on 21 May 2010

Mouse models of cystic fibrosis: phenotypic analysis and research applications

scientific article published on June 2011

Peroxiredoxin 6 fails to limit phospholipid peroxidation in lung from Cftr-knockout mice subjected to oxidative challenge

scientific article

Phospholipases A2 and platelet-activating-factor acetylhydrolase in patients with acute respiratory distress syndrome.

scientific article published in April 2005

Pseudomonas aeruginosa LPS or flagellin are sufficient to activate TLR-dependent signaling in murine alveolar macrophages and airway epithelial cells

scientific article

Pseudomonas aeruginosa eradicates Staphylococcus aureus by manipulating the host immunity.

scientific article published on 7 October 2014

Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: first steps towards treatment and prevention

scientific article

Secreted group IIA phospholipase A2 protects humans against the group B streptococcus: experimental and clinical evidence.

scientific article published on 30 July 2013

Staphylococcus aureus Adenosine Inhibits sPLA2-IIA-Mediated Host Killing in the Airways.

scientific article published on 22 April 2015

Surfactant protein A inhibits lipopolysaccharide-induced in vivo production of interleukin-10 by mononuclear phagocytes during lung inflammation.

scientific article published in March 2003

Surfactant protein-A and phosphatidylglycerol suppress type IIA phospholipase A2 synthesis via nuclear factor-kappaB.

scientific article published on 25 July 2003

Toll-like receptor 9 deficiency protects mice against Pseudomonas aeruginosa lung infection

scientific article

Type II Secretion System of Pseudomonas aeruginosa: In Vivo Evidence of a Significant Role in Death Due to Lung Infection ⬇️

scientific article published on May 15, 2011

Type-IIA secreted phospholipase A2 is an endogenous antibiotic-like protein of the host

scientific article published on 06 February 2010

ZapE is a novel cell division protein interacting with FtsZ and modulating the Z-ring dynamics

scientific article published on 04 March 2014

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