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List of works by John Sampson

A Pilot Study of IL-2Rα Blockade during Lymphopenia Depletes Regulatory T-cells and Correlates with Enhanced Immunity in Patients with Glioblastoma ⬇️

scientific article published on February 27, 2012

A Supramolecular Vaccine Platform Based on α-Helical Peptide Nanofibers

scientific article published on 11 September 2017

A comprehensive outlook on intracerebral therapy of malignant gliomas.

scientific article

A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas

scientific article published on 11 March 2009

A cytokine cocktail directly modulates the phenotype of DC-enriched anti-tumor T cells to convey potent anti-tumor activities in a murine model.

scientific article published on 27 August 2013

A genetically modified allogeneic cellular vaccine generates MHC class I-restricted cytotoxic responses against tumor-associated antigens and protects against CNS tumors in vivo ⬇️

scientific article published on September 1, 1997

A promising cancer vaccine.

scientific article published in March 2011

A simple and enzyme-free method for processing infiltrating lymphocytes from small mouse tumors for ELISpot analysis

scientific article published on 31 May 2018

Accuracy of Novel Computed Tomography-Guided Frameless Stereotactic Drilling and Catheter System in Human Cadavers.

scientific article published on 25 July 2017

Advances and challenges: dendritic cell vaccination strategies for glioblastoma.

scientific article

Advances in Immunotherapy: Abhijit Guha Award Presentation.

scientific article published in August 2016

Alternating Electric Fields for the Treatment of Glioblastoma

scientific article published in December 2015

An EGFRvIII-targeted bispecific T-cell engager overcomes limitations of the standard of care for glioblastoma.

scientific article

Antibody-based immunotherapy for malignant glioma

scientific article

Are BiTEs the "missing link" in cancer therapy?

scientific article

Author Correction: Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors

scientific article published on 01 March 2019

Biopsy of enlarging lesions after stereotactic radiosurgery for brain metastases frequently reveals radiation necrosis.

scientific article published on 3 May 2017

Bispecific antibodies engage T cells for antitumor immunotherapy ⬇️

scientific article published on March 30, 2011

Brain Tumor Microenvironment and Host State: Implications for Immunotherapy

scientific article published on 25 February 2019

Brain immunology and immunotherapy in brain tumours

scientific article published on 05 December 2019

CD27 stimulation unveils the efficacy of linked class I/II peptide vaccines in poorly immunogenic tumors by orchestrating a coordinated CD4/CD8 T cell response

scientific article published on 05 September 2018

Challenges to curing primary brain tumours

scientific article published on 01 August 2019

Chemokines as adjuvants for immunotherapy: implications for immune activation with CCL3.

scientific article

Chimeric antigen receptor engineered T cells can eliminate brain tumors and initiate long-term protection against recurrence.

scientific article published on 3 July 2014

Cholesterol granuloma of the lateral ventricle. Case report.

scientific article published in February 2008

Clinical applications of a peptide-based vaccine for glioblastoma.

scientific article

Clinical trial end points for high-grade glioma: the evolving landscape.

scientific article published on 09 February 2011

Contemporary surgical management of vestibular schwannomas: analysis of complications and lessons learned over the past decade.

scientific article

Convection-enhanced delivery

scientific article published on 27 May 2011

Defining the optimal planning target volume in image-guided stereotactic radiosurgery of brain metastases: results of a randomized trial

scientific article

Delivering therapy to target: improving the odds for successful drug development.

scientific article published on July 2016

Demographics, prognosis, and therapy in 702 patients with brain metastases from malignant melanoma.

scientific article published on January 1998

Dendritic Cells Pulsed with a Tumor-specific Peptide Induce Long-lasting Immunity and Are Effective against Murine Intracerebral Melanoma

scientific article published on 01 January 2002

Detection of infusate leakage in the brain using real-time imaging of convection-enhanced delivery.

scientific article

Differential Immune Microenvironments and Response to Immune Checkpoint Blockade among Molecular Subtypes of Murine Medulloblastoma.

scientific article published on 24 September 2015

Disparities in care

scientific article published on 08 July 2011

EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss.

scientific article published on 18 December 2013

Editorial on "heat shock protein peptide complex-96 (HSPPC-96) vaccination for recurrent glioblastoma: a phase II, single arm trial".

scientific article published on January 2014

Editorial: Convection-enhanced delivery.

scientific article published on 21 September 2012

Editorial: Not everything that matters can be measured and not everything that can be measured matters.

scientific article

Editorial: Turning fluorescence into black and white

scientific article published on 3 April 2015

Effective effectors: How T cells access and infiltrate the central nervous system

scientific article published on 14 December 2018

Emerging immunotherapies for glioblastoma

scientific article published on June 2016

Enhanced oncolytic virotherapy through oxidative stress inhibition

scientific article published on November 2013

Enhancing dendritic cell-based vaccination for highly aggressive glioblastoma.

scientific article

Enzyme redesign guided by cancer-derived IDH1 mutations

scientific article (publication date: November 2012)

Epidermal growth factor receptor and variant III targeted immunotherapy.

scientific article

Facial pain due to vascular lesions of the brain stem relieved by dorsal root entry zone lesions in the nucleus caudalis. Report of two cases

scientific article published on September 1, 1992

Generation of CAR T cells for adoptive therapy in the context of glioblastoma standard of care.

scientific article

Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity.

scientific article published on 29 November 2006

Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma ⬇️

scientific article published on December 10, 2010

Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody

scientific article published on September 2013

Hyaluronic acid based low viscosity hydrogel as a novel carrier for Convection Enhanced Delivery of CAR T cells

scientific article published on 21 July 2018

Imaging of Convection Enhanced Delivery of Toxins in Humans ⬇️

scientific article published on March 15, 2011

Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma ⬇️

scientific article published on October 4, 2010

Immunological targeting of cytomegalovirus for glioblastoma therapy

scientific article

Immunotherapy Gone Viral: Bortezomib and oHSV Enhance Antitumor NK-Cell Activity

scientific article

Immunotherapy advances for glioblastoma

scientific article

Immunotherapy approaches for malignant glioma from 2007 to 2009.

scientific article published on July 2010

Immunotherapy coming of age: What will it take to make it standard of care for glioblastoma? ⬇️

scientific article published on December 10, 2010

Immunotherapy for Brain Tumors.

scientific article

Immunotherapy for Glioblastoma: Adoptive T-cell Strategies

scientific article published on 16 November 2018

Immunotherapy for malignant glioma

scientific article

Immunotherapy for primary brain tumors: no longer a matter of privilege

scientific article

Immunotherapy response assessment in neuro-oncology: a report of the RANO working group

scientific article

Immunotherapy with Tumor Vaccines for the Treatment of Malignant Gliomas ⬇️

scientific article published on December 1, 2012

Increased proportion of FoxP3+ regulatory T cells in tumor infiltrating lymphocytes is associated with tumor recurrence and reduced survival in patients with glioblastoma.

scientific article published on 3 January 2015

Institutional Review of Mortality in 5434 Consecutive Neurosurgery Patients: Are We Improving?

scientific article published on 28 December 2017

Intracerebral delivery of a third generation EGFRvIII-specific chimeric antigen receptor is efficacious against human glioma.

scientific article published on 17 September 2013

Introduction. Update on adult neuro-oncology

scientific article published on 01 June 2018

Is cytomegalovirus a therapeutic target in glioblastoma?

scientific article

Leveraging chemotherapy-induced lymphopenia to potentiate cancer immunotherapy.

scientific article published on 3 July 2014

Local production of TGF β1 inhibits cerebral edema, enhances TNF-α induced apoptosis and improves survival in a murine glioma model ⬇️

scientific article published on June 1, 1998

Low-grade glioma

scientific article published on 16 July 2010

MTAP Loss Promotes Stemness in Glioblastoma and Confers Unique Susceptibility to Purine Starvation

scientific article published on 30 April 2019

Melanoma immunotherapy using mature DCs expressing the constitutive proteasome.

scientific article

Methodology and reporting of meta-analyses in the neurosurgical literature

scientific article published on 24 January 2014

Monitoring Radiographic Brain Tumor Progression ⬇️

scientific article published on March 15, 2011

Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans ⬇️

scientific article published on July 18, 2011

Our failure to advance new treatments for glioma to market.

scientific article

Paraganglioma of the head and neck: long-term local control with radiotherapy.

scientific article published on June 2009

Patient validation of retrospective data.

scientific article published on 7 August 2015

Peptide vaccines for the treatment of glioblastoma.

scientific article published on 10 December 2014

Pharmacokinetic Analysis of a Novel Human EGFRvIII:CD3 Bispecific Antibody in Plasma and Whole Blood Using a High-Resolution Targeted Mass Spectrometry Approach

scientific article published on 19 July 2019

Poliovirus receptor CD155-targeted oncolysis of glioma

scientific article published on July 2004

Preconditioning Vaccine Sites for mRNA-Transfected Dendritic Cell Therapy and Antitumor Efficacy.

scientific article published on January 2016

Preventing Lck Activation in CAR T Cells Confers Treg Resistance but Requires 4-1BB Signaling for Them to Persist and Treat Solid Tumors in Nonlymphodepleted Hosts

scientific article published on 13 November 2018

Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals differential expression of the immunologic transcriptome compared with T cells from healthy volunteers.

scientific article published in December 2006

Prospect of rindopepimut in the treatment of glioblastoma.

scientific article published on 5 March 2017

Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: implications for drug development.

scientific article published on 12 February 2015

Radiotherapy and radiosurgery for tumors of the central nervous system.

scientific article published on 19 March 2013

Rational design and generation of recombinant control reagents for bispecific antibodies through CDR mutagenesis.

scientific article published on 24 June 2013

Recognition and killing of autologous, primary glioblastoma tumor cells by human cytomegalovirus pp65-specific cytotoxic T cells.

scientific article

Recurrent malignant gliomas

scientific article

Regulatory T cells move in when gliomas say "I Do".

scientific article published on 10 October 2012

Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'

scientific article published on 01 August 2019

Resection and survival.

scientific article published on 16 March 2012

Resection of vestibular schwannomas

scientific article published on 21 January 2011

Response

Rindopepimut: a promising immunotherapeutic for the treatment of glioblastoma multiforme

scientific article published on January 2014

Rindopepimut: anti-EGFRvIII peptide vaccine, oncolytic

scientific article published on March 2013

Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors

scientific article published on 13 August 2018

Serum elevation of B lymphocyte stimulator does not increase regulatory B cells in glioblastoma patients undergoing immunotherapy.

scientific article published on 12 January 2016

Single fraction stereotactic radiosurgery for multiple brain metastases

scientific article published on 11 September 2017

Standard of care and future pharmacological treatment options for malignant glioma: an urgent need for screening and identification of novel tumor-specific antigens

scientific article

Stereotactic radiosurgery and bevacizumab for recurrent glioblastoma multiforme.

scientific article published in June 2012

Subarachnoid hemorrhage trials.

scientific article published on 5 October 2012

Systemic activation of antigen-presenting cells via RNA-loaded nanoparticles.

scientific article

Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma.

scientific article published on 17 December 2012

Targeting miR-23a in CD8+ cytotoxic T lymphocytes prevents tumor-dependent immunosuppression

scientific article

Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma.

scientific article

Temozolomide treatment outcomes and immunotherapy efficacy in brain tumor

scientific article published on 19 August 2020

The PEPvIII-KLH (CDX-110) vaccine in glioblastoma multiforme patients

scientific article published on August 2009

The Safety of available immunotherapy for the treatment of glioblastoma.

scientific article published on 17 December 2016

The Use of Motor Mapping to Aid Resection of Eloquent Gliomas ⬇️

scientific article published on February 28, 2012

The current state of immunotherapy for gliomas: an eye toward the future

scientific article published on 01 September 2019

The limitations of imaging response criteria.

scientific article published in November 2012

The role of tregs in glioma-mediated immunosuppression: potential target for intervention.

scientific article published on January 2010

Therapeutic approaches for HER2-positive brain metastases: circumventing the blood-brain barrier.

scientific article published on 22 June 2012

Thickness of subcutaneous fat as a risk factor for infection in cervical spine fusion surgery.

scientific article published on February 2013

Toxin-Based Targeted Therapy for Malignant Brain Tumors ⬇️

scientific article published on February 9, 2012

Vaccination strategies for neuro-oncology

scientific article

Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy

scientific article published on 13 January 2021

Viruses in the treatment of malignant glioma.

scientific article

miR-23a blockade enhances adoptive T cell transfer therapy by preserving immune-competence in the tumor microenvironment

scientific article

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