List of works - Frances A. Lemckert

Calpain cleavage within dysferlin exon 40a releases a synaptotagmin-like module for membrane repair.

scientific article

Calpains, cleaved mini-dysferlinC72, and L-type channels underpin calcium-dependent muscle membrane repair.

scientific article published in March 2013

Challenging cytokine redundancy: inflammatory cell movement and clinical course of experimental autoimmune encephalomyelitis are normal in lymphotoxin-deficient, but not tumor necrosis factor-deficient, mice

scientific journal article

Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow

scientific article published on 01 September 2006

Critical Points of Tumor Necrosis Factor Action in Central Nervous System Autoimmune Inflammation Defined by Gene Targeting ⬇️

scientific article published on November 3, 1997

Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue

scientific journal article

Divergent regulation of the sarcomere and the cytoskeleton.

scientific article published on 18 October 2007

Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch.

scientific article published in April 2011

Enzymatic cleavage of myoferlin releases a dual C2-domain module linked to ERK signalling.

scientific article published on 9 February 2017

Functional identity of the gamma tropomyosin gene: Implications for embryonic development, reproduction and cell viability.

scientific article

Gamma tropomyosin gene products are required for embryonic development.

scientific article published on March 2004

Generation of splenic follicular structure and B cell movement in tumor necrosis factor-deficient mice.

scientific article

Hypertrophy and dietary tyrosine ameliorate the phenotypes of a mouse model of severe nemaline myopathy

article

Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor.

scientific article published on 19 January 2016

Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans

scientific journal article

Lymphotoxin controls alphaEbeta7-integrin expression by peripheral CD8+ T cells.

scientific article published in August 2001

Negative autoregulation of GTF2IRD1 in Williams-Beuren syndrome via a novel DNA binding mechanism

scientific article

New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2.

scientific article published on 12 March 2010

Oxidative stress and pathology in muscular dystrophies: focus on protein thiol oxidation and dysferlinopathies.

scientific article published on 15 February 2013

The murine stanniocalcin 2 gene is a negative regulator of postnatal growth

scientific journal article

Tumor necrosis factor blockade in actively induced experimental autoimmune encephalomyelitis prevents clinical disease despite activated T cell infiltration to the central nervous system

scientific article published on 01 August 1997

List of works by Frances A. Lemckert

Calpain cleavage within dysferlin exon 40a releases a synaptotagmin-like module for membrane repair.

Calpains, cleaved mini-dysferlinC72, and L-type channels underpin calcium-dependent muscle membrane repair.

Challenging cytokine redundancy: inflammatory cell movement and clinical course of experimental autoimmune encephalomyelitis are normal in lymphotoxin-deficient, but not tumor necrosis factor-deficient, mice

Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow

Critical Points of Tumor Necrosis Factor Action in Central Nervous System Autoimmune Inflammation Defined by Gene Targeting ⬇️

Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue

Divergent regulation of the sarcomere and the cytoskeleton.

Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch.

Enzymatic cleavage of myoferlin releases a dual C2-domain module linked to ERK signalling.

Functional identity of the gamma tropomyosin gene: Implications for embryonic development, reproduction and cell viability.

Gamma tropomyosin gene products are required for embryonic development.

Generation of splenic follicular structure and B cell movement in tumor necrosis factor-deficient mice.

Hypertrophy and dietary tyrosine ameliorate the phenotypes of a mouse model of severe nemaline myopathy

Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor.

Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans

Lymphotoxin controls alphaEbeta7-integrin expression by peripheral CD8+ T cells.

Negative autoregulation of GTF2IRD1 in Williams-Beuren syndrome via a novel DNA binding mechanism

New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2.

Oxidative stress and pathology in muscular dystrophies: focus on protein thiol oxidation and dysferlinopathies.

The murine stanniocalcin 2 gene is a negative regulator of postnatal growth

Tumor necrosis factor blockade in actively induced experimental autoimmune encephalomyelitis prevents clinical disease despite activated T cell infiltration to the central nervous system