List of works - Tim Felton

A 27-Year-Old Woman With Acute, Severe Asthma Who Developed Respiratory Failure

scientific article published on 01 March 2010

A rare case of shock.

scientific article published on August 2003

Achieving high standards of training

scientific article published on 01 December 2009

An unusual contraindication to the use of non-invasive ventilation in A&E

scientific article published on 26 June 2010

Anidulafungin for neonatal hematogenous Candida meningoencephalitis: identification of candidate regimens for humans using a translational pharmacological approach.

scientific article published on 28 November 2011

Aspergillus bronchitis without significant immunocompromise.

scientific article published in December 2012

BTS/ICS guideline for the ventilatory management of acute hypercapnic respiratory failure in adults

scientific article

Blood pleurodesis for the medical management of pneumothorax.

scientific article published on March 2009

British Thoracic Society/Intensive Care Society Guideline for the ventilatory management of acute hypercapnic respiratory failure in adults

scientific article published on 14 March 2016

Capsaicin-evoked cough responses in asthmatic patients: Evidence for airway neuronal dysfunction

scientific article

Carbapenem-Resistant Enterobacteriaceae Infections: Results From a Retrospective Series and Implications for the Design of Prospective Clinical Trials.

scientific article published on June 2017

Cardiorespiratory interaction

scientific article published on 01 June 2015

Comparison of piperacillin exposure in the lungs of critically ill patients and healthy volunteers.

scientific article published on 29 January 2018

Computed tomography scanning in the prone position for a critically hypoxic patient with COVID-19

scientific article published on 01 January 2020

Effect and Safety of Meropenem-Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial

scientific article published on 01 October 2018

Efficacy of an abbreviated induction regimen of amphotericin B deoxycholate for cryptococcal meningoencephalitis: 3 days of therapy is equivalent to 14 days.

scientific article published on 28 January 2014

Estimate of the number of patients eligible for treatment with drotrecogin alfa (activated) based on differing international indications: post-hoc analysis of an inception cohort study in Australia and New Zealand.

scientific article published in April 2006

Global survey on nebulization of antimicrobial agents in mechanically ventilated patients: a call for international guidelines

scientific article

How severe is antibiotic pharmacokinetic variability in critically ill patients and what can be done about it?

scientific article published on 30 April 2014

Impact of Bolus dosing versus continuous infusion of Piperacillin and Tazobactam on the development of antimicrobial resistance in Pseudomonas aeruginosa.

scientific article published on 03 September 2013

Impact of a diagnostics-driven antifungal stewardship programme in a UK tertiary referral teaching hospital

scientific article published on 01 December 2018

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

scientific article

Individualization of piperacillin dosing for critically ill patients: dosing software to optimize antimicrobial therapy ⬇️

scientific article

Intratracheal Administration of Antimicrobial Agents in Mechanically Ventilated Adults: An International Survey on Delivery Practices and Safety.

scientific article

Invasive pulmonary aspergillosis is associated with adverse clinical outcomes in critically ill patients receiving veno-venous extracorporeal membrane oxygenation.

scientific article

Isavuconazole and voriconazole for the treatment of chronic pulmonary aspergillosis: A retrospective comparison of rates of adverse events

scientific article published on 15 January 2019

Life-threatening pulmonary hypertension and right ventricular failure complicating calcium and phosphate replacement in the intensive care unit.

scientific article published in January 2006

Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19

scientific article published on 01 September 2020

Nebulization of Antiinfective Agents in Invasively Mechanically Ventilated Adults: A Systematic Review and Meta-analysis

scientific article

Non-directed bronchial lavage is a safe method for sampling the respiratory tract in critically ill patient

scientific article published on 13 November 2018

Peripheral neuropathy in patients on long-term triazole antifungal therapy

article

Pharmacodynamics of Isavuconazole in a Dynamic In Vitro Model of Invasive Pulmonary Aspergillosis

scientific article

Pharmacodynamics of itraconazole against Aspergillus fumigatus in an in vitro model of the human alveolus: perspectives on the treatment of triazole-resistant infection and utility of airway administration.

scientific article

Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients.

scientific article published on 18 April 2013

Pharmacodynamics of vancomycin for CoNS infection: experimental basis for optimal use of vancomycin in neonates

scientific article published on 10 January 2016

Pharmacokinetics and pharmacodynamics of anidulafungin for experimental Candida endophthalmitis: insights into the utility of echinocandins for treatment of a potentially sight-threatening infection.

scientific article published on 31 October 2012

Population pharmacokinetics of conventional and intermittent dosing of liposomal amphotericin B in adults: a first critical step for rational design of innovative regimens

scientific article

Population pharmacokinetics of extended-infusion piperacillin-tazobactam in hospitalized patients with nosocomial infections

scientific article

Population pharmacokinetics of teicoplanin in children

scientific article

Posaconazole: the case for therapeutic drug monitoring.

scientific article published on February 2012

Pulmonary penetration of piperacillin and tazobactam in critically ill patients.

scientific article

Safety and feasibility of above cuff vocalisation for ventilator-dependant patients with tracheostomies

scientific article published on 28 March 2018

Surveillance non-directed bronchial lavage allows confident use of focused antibiotics in the management of ventilator-associated pneumonia

scientific article published on 09 March 2010

The potential role of exhaled breath analysis in the diagnostic process of pneumonia - a systematic review.

scientific article

The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections

scientific article published on 13 April 2017

Tissue penetration of antifungal agents.

scientific article published on January 2014

Use of nebulized antimicrobials for the treatment of respiratory infections in invasively mechanically ventilated adults: a position paper from the European Society of Clinical Microbiology and Infectious Diseases.

scientific article published on 13 April 2017

List of works by Tim Felton

A 27-Year-Old Woman With Acute, Severe Asthma Who Developed Respiratory Failure

A rare case of shock.

Achieving high standards of training

An unusual contraindication to the use of non-invasive ventilation in A&E

Anidulafungin for neonatal hematogenous Candida meningoencephalitis: identification of candidate regimens for humans using a translational pharmacological approach.

Aspergillus bronchitis without significant immunocompromise.

BTS/ICS guideline for the ventilatory management of acute hypercapnic respiratory failure in adults

Blood pleurodesis for the medical management of pneumothorax.

British Thoracic Society/Intensive Care Society Guideline for the ventilatory management of acute hypercapnic respiratory failure in adults

Capsaicin-evoked cough responses in asthmatic patients: Evidence for airway neuronal dysfunction

Carbapenem-Resistant Enterobacteriaceae Infections: Results From a Retrospective Series and Implications for the Design of Prospective Clinical Trials.

Cardiorespiratory interaction

Comparison of piperacillin exposure in the lungs of critically ill patients and healthy volunteers.

Computed tomography scanning in the prone position for a critically hypoxic patient with COVID-19

Effect and Safety of Meropenem-Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial

Efficacy of an abbreviated induction regimen of amphotericin B deoxycholate for cryptococcal meningoencephalitis: 3 days of therapy is equivalent to 14 days.

Estimate of the number of patients eligible for treatment with drotrecogin alfa (activated) based on differing international indications: post-hoc analysis of an inception cohort study in Australia and New Zealand.

Global survey on nebulization of antimicrobial agents in mechanically ventilated patients: a call for international guidelines

How severe is antibiotic pharmacokinetic variability in critically ill patients and what can be done about it?

Impact of Bolus dosing versus continuous infusion of Piperacillin and Tazobactam on the development of antimicrobial resistance in Pseudomonas aeruginosa.

Impact of a diagnostics-driven antifungal stewardship programme in a UK tertiary referral teaching hospital

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

Individualization of piperacillin dosing for critically ill patients: dosing software to optimize antimicrobial therapy ⬇️

Intratracheal Administration of Antimicrobial Agents in Mechanically Ventilated Adults: An International Survey on Delivery Practices and Safety.

Invasive pulmonary aspergillosis is associated with adverse clinical outcomes in critically ill patients receiving veno-venous extracorporeal membrane oxygenation.

Isavuconazole and voriconazole for the treatment of chronic pulmonary aspergillosis: A retrospective comparison of rates of adverse events

Life-threatening pulmonary hypertension and right ventricular failure complicating calcium and phosphate replacement in the intensive care unit.

Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19

Nebulization of Antiinfective Agents in Invasively Mechanically Ventilated Adults: A Systematic Review and Meta-analysis

Non-directed bronchial lavage is a safe method for sampling the respiratory tract in critically ill patient

Peripheral neuropathy in patients on long-term triazole antifungal therapy

Pharmacodynamics of Isavuconazole in a Dynamic In Vitro Model of Invasive Pulmonary Aspergillosis

Pharmacodynamics of itraconazole against Aspergillus fumigatus in an in vitro model of the human alveolus: perspectives on the treatment of triazole-resistant infection and utility of airway administration.

Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients.

Pharmacodynamics of vancomycin for CoNS infection: experimental basis for optimal use of vancomycin in neonates

Pharmacokinetics and pharmacodynamics of anidulafungin for experimental Candida endophthalmitis: insights into the utility of echinocandins for treatment of a potentially sight-threatening infection.

Population pharmacokinetics of conventional and intermittent dosing of liposomal amphotericin B in adults: a first critical step for rational design of innovative regimens

Population pharmacokinetics of extended-infusion piperacillin-tazobactam in hospitalized patients with nosocomial infections

Population pharmacokinetics of teicoplanin in children

Posaconazole: the case for therapeutic drug monitoring.

Pulmonary penetration of piperacillin and tazobactam in critically ill patients.

Safety and feasibility of above cuff vocalisation for ventilator-dependant patients with tracheostomies

Surveillance non-directed bronchial lavage allows confident use of focused antibiotics in the management of ventilator-associated pneumonia

The potential role of exhaled breath analysis in the diagnostic process of pneumonia - a systematic review.

The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections

Tissue penetration of antifungal agents.

Use of nebulized antimicrobials for the treatment of respiratory infections in invasively mechanically ventilated adults: a position paper from the European Society of Clinical Microbiology and Infectious Diseases.