List of works - Frédéric Adam

A Novel Single-Domain Antibody Against von Willebrand Factor A1 Domain Resolves Leukocyte Recruitment and Vascular Leakage During Inflammation-Brief Report.

scientific article published on 22 June 2017

A genetically-engineered von Willebrand disease type 2B mouse model displays defects in hemostasis and inflammation.

scientific article published on 23 May 2016

A mutation in the gene coding for the sialic acid transporter SLC35A1 is required for platelet life span but not proplatelet formation

article

A novel missense mutation in a leucine-rich repeat of GPIbα in a Bernard-Soulier variant reduces shear-dependent adherence on von Willebrand factor

scientific article published on 01 July 2019

Analyses of cellular multimerin 1 receptors: in vitro evidence of binding mediated by alphaIIbbeta3 and alphavbeta3

scientific article published in November 2005

Anticoagulant and antithrombotic properties of platelet protease nexin-1

scientific article

Apelin: an antithrombotic factor that inhibits platelet function.

scientific article published on 3 December 2015

Apoptotic Platelet Events Are Not Observed in Severe von Willebrand Disease-Type 2B Mutation p.V1316M.

scientific article

Characterization of the Annonaceous acetogenin, annonacinone, a natural product inhibitor of plasminogen activator inhibitor-1.

scientific article published on 23 November 2016

Full activation of mouse platelets requires ADP secretion regulated by SERCA3 ATPase-dependent calcium stores.

scientific article published on 14 June 2016

Gain-of-Function Mutation in Filamin A Potentiates Platelet Integrin αIIbβ3 Activation

scientific article

Glycoprotein Ib-mediated platelet activation. A signalling pathway triggered by thrombin.

scientific article published in July 2003

Heterogeneity of platelet functional alterations in patients with filamin A mutations.

scientific article

Human platelets contain forms of factor V in disulfide-linkage with multimerin.

scientific article

Insights into abnormal hemostasis in the Quebec platelet disorder from analyses of clot lysis.

scientific article published in May 2006

Involvement of the Mitogen-activated Protein Kinase c-Jun NH2-terminal Kinase 1 in Thrombus Formation

scientific article published on 04 September 2007

Kinesin-1 Is a New Actor Involved in Platelet Secretion and Thrombus Stability.

scientific article published on 8 March 2018

LIM kinase/cofilin dysregulation promotes macrothrombocytopenia in severe von Willebrand disease-type 2B.

scientific article

Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott-Aldrich syndrome

scientific article published on 24 January 2022

Mitogen-activated protein kinases in hemostasis and thrombosis

scientific article published on December 2008

Protease-activating Receptor-4 Induces Full Platelet Spreading on a Fibrinogen Matrix

scientific article published on 02 January 2007

Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence

scientific article published on 28 February 2019

Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity

scientific article

TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology

scientific article published on 01 December 2018

Thrombin interaction with platelet membrane glycoprotein Ib alpha.

scientific article published in November 2003

Thrombocytopenia resulting from mutations in filamin A can be expressed as an isolated syndrome.

scientific article

von Willebrand factor mutation promotes thrombocytopathy by inhibiting integrin αIIbβ3.

scientific article

List of works by Frédéric Adam

A Novel Single-Domain Antibody Against von Willebrand Factor A1 Domain Resolves Leukocyte Recruitment and Vascular Leakage During Inflammation-Brief Report.

A genetically-engineered von Willebrand disease type 2B mouse model displays defects in hemostasis and inflammation.

A mutation in the gene coding for the sialic acid transporter SLC35A1 is required for platelet life span but not proplatelet formation

A novel missense mutation in a leucine-rich repeat of GPIbα in a Bernard-Soulier variant reduces shear-dependent adherence on von Willebrand factor

Analyses of cellular multimerin 1 receptors: in vitro evidence of binding mediated by alphaIIbbeta3 and alphavbeta3

Anticoagulant and antithrombotic properties of platelet protease nexin-1

Apelin: an antithrombotic factor that inhibits platelet function.

Apoptotic Platelet Events Are Not Observed in Severe von Willebrand Disease-Type 2B Mutation p.V1316M.

Characterization of the Annonaceous acetogenin, annonacinone, a natural product inhibitor of plasminogen activator inhibitor-1.

Full activation of mouse platelets requires ADP secretion regulated by SERCA3 ATPase-dependent calcium stores.

Gain-of-Function Mutation in Filamin A Potentiates Platelet Integrin αIIbβ3 Activation

Glycoprotein Ib-mediated platelet activation. A signalling pathway triggered by thrombin.

Heterogeneity of platelet functional alterations in patients with filamin A mutations.

Human platelets contain forms of factor V in disulfide-linkage with multimerin.

Insights into abnormal hemostasis in the Quebec platelet disorder from analyses of clot lysis.

Involvement of the Mitogen-activated Protein Kinase c-Jun NH2-terminal Kinase 1 in Thrombus Formation

Kinesin-1 Is a New Actor Involved in Platelet Secretion and Thrombus Stability.

LIM kinase/cofilin dysregulation promotes macrothrombocytopenia in severe von Willebrand disease-type 2B.

Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott-Aldrich syndrome

Mitogen-activated protein kinases in hemostasis and thrombosis

Protease-activating Receptor-4 Induces Full Platelet Spreading on a Fibrinogen Matrix

Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence

Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity

TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology

Thrombin interaction with platelet membrane glycoprotein Ib alpha.

Thrombocytopenia resulting from mutations in filamin A can be expressed as an isolated syndrome.

von Willebrand factor mutation promotes thrombocytopathy by inhibiting integrin αIIbβ3.