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List of works by Ben Chi Bun Ko

Aldose reductase-deficient mice develop nephrogenic diabetes insipidus

scientific article

Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosis

scientific article published on 2 March 2010

Depletion of sirtuin 1 (SIRT1) leads to epigenetic modifications of telomerase (TERT) gene in hepatocellular carcinoma cells

scientific article published on 8 January 2014

Design, synthesis, and evaluation of a new class of noncyclic 1,3-dicarbonyl compounds as PPARalpha selective activators.

scientific article

Diabetic nephropathy is associated with the 5'-end dinucleotide repeat polymorphism of the aldose reductase gene in Chinese subjects with Type 2 diabetes

scientific article published on 01 February 2002

Discovery of osmosensitive transcriptional regulation of human cytochrome P450 3As by the tonicity-responsive enhancer binding protein (nuclear factor of activated T cells 5).

scientific article

Embryonic Lethality in Mice Lacking the Nuclear Factor of Activated T Cells 5 Protein Due to Impaired Cardiac Development and Function ⬇️

scientific article published on July 12, 2011

Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicity-responsive enhancer-binding protein (OREBP/TonEBP)

scientific article (publication date: 29 November 2002)

Generation and characterization of sodium-dicarboxylate cotransporter-deficient mice

scientific article published on 04 April 2007

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

In Vitro and In Vivo Characterizations of Chiglitazar, a Newly Identified PPAR Pan-Agonist.

scientific article

Inducible nucleosome depletion at OREBP-binding-sites by hypertonic stress.

scientific article

Methanogen population in a marine biofilm corrosive to mild steel.

scientific article published on 18 July 2003

NFAT5 in cellular adaptation to hypertonic stress - regulations and functional significance

scientific article published on 23 April 2013

Nuclear factor of activated T cells 5 deficiency increases the severity of neuronal cell death in ischemic injury

scientific article published on 18 January 2012

Osmotic response element-binding protein (OREBP) is an essential regulator of the urine concentrating mechanism.

scientific article published on 3 September 2004

Overexpression of aldose reductase in liver cancers may contribute to drug resistance

scientific article

Preparation of N-sulfonyl- and N-carbonyl-11-azaartemisinins with greatly enhanced thermal stabilities: in vitro antimalarial activities.

scientific article published on October 2007

Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.

scientific article published on August 2005

Pseudolaric acids: isolation, bioactivity and synthetic studies.

scientific article published on 20 April 2010

Purification, identification, and characterization of an osmotic response element binding protein

scientific article (publication date: 2 April 2000)

Regulation of nucleocytoplasmic trafficking of transcription factor OREBP/TonEBP/NFAT5.

scientific article published on 16 June 2006

Role of nuclear factor of activated T-cells 5 in regulating hypertonic-mediated secretin receptor expression in kidney collecting duct cells

scientific article published on 11 April 2016

Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth.

scientific article published on 28 April 2011

Sirtuin 1 regulates hepatitis B virus transcription and replication by targeting transcription factor AP-1.

scientific article published on 11 December 2013

Sirtuin 3 inhibits hepatocellular carcinoma growth through the glycogen synthase kinase-3β/BCL2-associated X protein-dependent apoptotic pathway

scientific article published on 27 April 2015

Subcellular Localization of a Fluorescent Artemisinin Derivative to Endoplasmic Reticulum

scientific article

Synthesis and Cytotoxicity Studies of Artemisinin Derivatives Containing Lipophilic Alkyl Carbon Chains

scientific article published on 01 April 2005

Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms.

scientific article

The CCCTC-binding factor (CTCF)-forkhead box protein M1 axis regulates tumour growth and metastasis in hepatocellular carcinoma.

scientific article published in September 2017

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