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List of works by Vivian Lui

Activity of the MEK inhibitor selumetinib (AZD6244; ARRY-142886) in nasopharyngeal cancer cell lines.

scientific article published on 8 May 2012

An RNA-directed nucleoside anti-metabolite, 1-(3-C-ethynyl-beta-d-ribo-pentofuranosyl)cytosine (ECyd), elicits antitumor effect via TP53-induced Glycolysis and Apoptosis Regulator (TIGAR) downregulation.

scientific article published on 26 February 2010

An update of ALK inhibitors in human clinical trials.

scientific article

An update on genomic-guided therapies for pediatric solid tumors.

scientific article published on 07 June 2017

Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells.

scientific article published on 23 June 2010

Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1.

scientific article published on 26 February 2007

Berberine suppresses Id-1 expression and inhibits the growth and development of lung metastases in hepatocellular carcinoma.

scientific article

Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts

scientific article

Blockade of PD-1 effectively inhibits in vivo malignant transformation of oral mucosa

scientific article published on 6 November 2017

Cancers of the lung, head and neck on the rise: perspectives on the genotoxicity of air pollution.

scientific article

Case Report: Exome sequencing reveals recurrent RETSAT mutations and a loss-of-function POLDIP2 mutation in a rare undifferentiated tongue sarcoma.

scientific article published on 26 April 2018

Comprehensive Exome Analysis of Immunocompetent Metastatic Head and Neck Cancer Models Reveals Patient Relevant Landscapes

scientific article published on 12 October 2020

Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cells.

scientific article

Effects of Salivary Mg on Head and Neck Carcinoma via TRPM7

scientific article published on 04 December 2018

Enhanced Antitumor Activity with Combining Effect of mTOR Inhibition and Microtubule Stabilization in Hepatocellular Carcinoma ⬇️

scientific article published on February 20, 2013

Enhanced IL-6/IL-6R Signaling Promotes Growth and Malignant Properties in EBV-Infected Premalignant and Cancerous Nasopharyngeal Epithelial Cells ⬇️

scientific article published on January 1, 2013

Erlotinib sensitivity of MAPK1p.D321N mutation in head and neck squamous cell carcinoma

scientific article published on 20 April 2020

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations

scientific article

Full-length Mst1 exhibits growth promoting function in human hepatocellular carcinoma cells.

scientific article published on 21 January 2013

Genetic landscape of metastatic and recurrent head and neck squamous cell carcinoma.

scientific article

Genomic Landscapes of EBV-Associated Nasopharyngeal Carcinoma vs. HPV-Associated Head and Neck Cancer

scientific article published on 21 June 2018

Genomic analysis of head and neck squamous cell carcinoma cell lines and human tumors: a rational approach to preclinical model selection.

scientific article published on 14 January 2014

Genomic profiles of nasopharyngeal carcinoma: The importance of histological subtyping and Epstein-Barr virus in situ assays.

scientific article published on 22 November 2017

Germline mutation and aberrant transcripts of WWOX in a syndrome with multiple primary tumors

scientific article published on 17 June 2019

Hypermethylation of NF-κB-Activating Protein-Like (NKAPL) Promoter in Hepatocellular Carcinoma Suppresses Its Expression and Predicts a Poor Prognosis.

scientific article published on 20 January 2018

Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation.

scientific article

Identification of mutations in the PYRIN-containing NLR genes (NLRP) in Head and Neck Squamous Cell Carcinoma.

scientific article published on 21 January 2014

Inactivation of ATP citrate lyase by Cucurbitacin B: A bioactive compound from cucumber, inhibits prostate cancer growth.

scientific article published on 29 March 2014

Induction of laryngeal cancer cell death by Ent-11-hydroxy-15-oxo-kaur-16-en-19-oic acid.

scientific article

JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth.

scientific article

K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr virus (EBV)--associated nasopharyngeal carcinoma cells.

scientific article published on 7 August 2010

Loss-of-Function PTPRD Mutations Lead to Increased STAT3 Activation and Sensitivity to STAT3 Inhibition in Head and Neck Cancer

scientific article

MAPK pathway mutations in head and neck cancer affect immune microenvironments and ErbB3 signaling

scientific article published on 07 May 2020

Mesenchymal stem cells participate in oral mucosa carcinogenesis by regulating T cell proliferation

scientific article published on 04 December 2018

Microneedle-Mediated Delivery of Lipid-Coated Cisplatin Nanoparticles for Efficient and Safe Cancer Therapy

scientific article published on 24 September 2018

PIK3CA, HRAS and PTEN in human papillomavirus positive oropharyngeal squamous cell carcinoma.

scientific article

Phosphorylation of TNF-alpha converting enzyme by gastrin-releasing peptide induces amphiregulin release and EGF receptor activation.

scholarly article

Preclinical evaluation of combined TKI-258 and RAD001 in hepatocellular carcinoma.

scientific article published on 2 April 2013

Preclinical evaluation of sunitinib as single agent or in combination with chemotherapy in nasopharyngeal carcinoma.

scientific article

Preclinical evaluation of the mTOR-PI3K inhibitor BEZ235 in nasopharyngeal cancer models.

scientific article published on 14 September 2013

Prediction of radiotherapy response with a 5-microRNA signature-based nomogram in head and neck squamous cell carcinoma

scientific article published on 23 February 2018

Primary chemotherapy and radiation as a treatment strategy for HPV-positive oropharyngeal cancer

scientific article

Prognostic significance of tumor infiltrating immune cells in oral squamous cell carcinoma

scientific article

Proteomic Characterization of Head and Neck Cancer Patient-Derived Xenografts

scientific article published on 18 December 2015

Quantitative proteomics analysis reveals molecular networks regulated by epidermal growth factor receptor level in head and neck cancer.

scientific article

Requirement of a carbon spacer in benzyl isothiocyanate-mediated cytotoxicity and MAPK activation in head and neck squamous cell carcinoma.

scientific article

Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1.

scientific article published on 30 October 2009

STAT3 activation contributes directly to Epstein-Barr virus-mediated invasiveness of nasopharyngeal cancer cells in vitro.

scientific article published in October 2009

STAT3 as a therapeutic target for Epstein-Barr virus (EBV) – associated nasopharyngeal carcinoma ⬇️

scientific article published on 06 December 2012

Sodium chloride (NaCl) potentiates digoxin-induced anti-tumor activity in small cell lung cancer

scientific article published on 05 September 2018

Specific down-regulation of HER-2/neu mediated by a chimeric U6 hammerhead ribozyme results in growth inhibition of human ovarian carcinoma.

scientific article

Stromal interleukin-33 promotes regulatory T cell-mediated immunosuppression in head and neck squamous cell carcinoma and correlates with poor prognosis

scientific article published on 25 October 2018

Sustained antitumor activity by co-targeting mTOR and the microtubule with temsirolimus/vinblastine combination in hepatocellular carcinoma.

scientific article published on 20 January 2012

Systemic administration of naked DNA encoding interleukin 12 for the treatment of human papillomavirus DNA-positive tumor.

scientific article published in January 2002

TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression.

scientific article published on 7 May 2012

TP53-induced glycolysis and apoptosis regulator promotes proliferation and invasiveness of nasopharyngeal carcinoma cells.

scientific article published on 12 December 2014

Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma.

scientific article

Targeting tumor hypoxia in nasopharyngeal carcinoma.

scientific article

The Fanconi anemia pathway: repairing the link between DNA damage and squamous cell carcinoma.

scientific article published on 17 January 2013

The Intersection between Oral Microbiota, Host Gene Methylation and Patient Outcomes in Head and Neck Squamous Cell Carcinoma

scientific article published on 18 November 2020

The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma.

scientific article published on 13 November 2017

Thrombomodulin (TM) in tumor cell differentiation and periphery blood immune microenvironment in oral squamous cell carcinoma

scientific article published on 18 March 2018

c-Src Activation Mediates Erlotinib Resistance in Head and Neck Cancer by Stimulating c-Met ⬇️

scientific article published on December 4, 2012

miR-466 is putative negative regulator of Coxsackie virus and Adenovirus Receptor

scientific article

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