List of works - Luiz O. F. Penalva

A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and Stemness

scientific article

A compendium of RNA-binding motifs for decoding gene regulation.

scientific article

A comprehensive in silico expression analysis of RNA binding proteins in normal and tumor tissue: Identification of potential players in tumor formation.

scientific article

A two-phase innate host response to alphavirus infection identified by mRNP-tagging in vivo.

scientific article

Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches

scientific article published on 31 May 2021

Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development

scientific article published on 19 April 2019

Before It Gets Started: Regulating Translation at the 5' UTR.

scientific article

Comparing Protein and mRNA Abundances to Protein Expression Regulation.

scientific article published in October 2011

ELF4 Is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State

scientific article published on 17 October 2019

From mechanisms to therapy: RNA processing's impact on human genetics

scientific article published on 2 September 2017

Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma

scientific article published on 10 June 2016

Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells

scientific article published on 22 January 2014

Global signatures of protein and mRNA expression levels

scientific article

IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC.

scientific article

Increased expression of the thyroid hormone nuclear receptor TRα1 characterizes intestinal tumors with high Wnt activity.

scientific article published on 24 July 2018

Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes

scientific article

Integrating shotgun proteomics and mRNA expression data to improve protein identification

scientific article

Leveraging cross-link modification events in CLIP-seq for motif discovery

scientific article

Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells

scientific article published on 18 November 2018

MSI1 Promotes the Expression of the GBM Stem Cell Marker CD44 by Impairing miRNA-Dependent Degradation

scientific article published on 05 December 2020

MicroRNA-16 and microRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1

scientific journal article

MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1.

scientific article

Mining gene functional networks to improve mass-spectrometry-based protein identification

scientific article published on 24 July 2009

Molecular characterization of the C-3 DNA puff gene of Rhynchosciara americana.

scientific article published in July 1997

Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit.

scientific article published on 25 July 2016

Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer

scientific article published on May 2013

Musashi1: an RBP with versatile functions in normal and cancer stem cells

scientific article published on January 1, 2012

Over-represented sequences located on 3' UTRs are potentially involved in regulatory functions

scientific article published on 3 October 2008

Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity.

scientific article published on 6 March 2018

Poly(A)-binding protein positively affects YB-1 mRNA translation through specific interaction with YB-1 mRNA.

scientific article

Post-transcription meets post-genomic: the saga of RNA binding proteins in a new era.

scientific article published on 7 July 2006

RIP-Chip analysis: RNA-Binding Protein Immunoprecipitation-Microarray (Chip) Profiling.

scientific article

RNA binding protein HuR regulates the expression of ABCA1.

scientific article

RNA processing as an alternative route to attack glioblastoma.

scientific article

RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma

scientific article

RNA-binding proteins to assess gene expression states of co-cultivated cells in response to tumor cells

scientific article

Riborex: fast and flexible identification of differential translation from Ribo-seq data

scientific article

Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line

scientific article

Site identification in high-throughput RNA-protein interaction data

scientific article

Switch in 3' splice site recognition between exon definition and splicing catalysis is important for sex-lethal autoregulation.

scientific article

Synergism of Pro-neurogenic miRNAs Provides a More Effective Strategy to Target Glioma Stem Cells

scientific article

The 3' end of the story: deciphering combinatorial interactions that control mRNA fate.

scientific article published on 29 November 2017

The Diverse Roles of RNA-Binding Proteins in Glioma Development

scientific article published on 01 January 2019

The RNA-Binding Protein Musashi1: A Major Player in Intestinal Epithelium Renewal and Colon Cancer Development ⬇️

scientific article published on January 1, 2012

The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation

scientific article published on 06 August 2020

The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells

scientific article published on January 2012

Translation regulation gets its ‘omics’ moment ⬇️

scientific article published on May 15, 2013

Two-tiered approach identifies a network of cancer and liver disease-related genes regulated by miR-122.

scientific article

Vascular biology and the sex of flies: regulation of vascular smooth muscle cell proliferation by wilms' tumor 1-associating protein.

scientific article published on October 2007

WTAP is a novel oncogenic protein in acute myeloid leukemia

scientific article

miR-124, -128, and -137 Orchestrate Neural Differentiation by Acting on Overlapping Gene Sets Containing a Highly Connected Transcription Factor Network.

scientific article published on 07 September 2015

List of works by Luiz O. F. Penalva

A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and Stemness

A compendium of RNA-binding motifs for decoding gene regulation.

A comprehensive in silico expression analysis of RNA binding proteins in normal and tumor tissue: Identification of potential players in tumor formation.

A two-phase innate host response to alphavirus infection identified by mRNP-tagging in vivo.

Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches

Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development

Before It Gets Started: Regulating Translation at the 5' UTR.

Comparing Protein and mRNA Abundances to Protein Expression Regulation.

ELF4 Is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State

From mechanisms to therapy: RNA processing's impact on human genetics

Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma

Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells

Global signatures of protein and mRNA expression levels

IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC.

Increased expression of the thyroid hormone nuclear receptor TRα1 characterizes intestinal tumors with high Wnt activity.

Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes

Integrating shotgun proteomics and mRNA expression data to improve protein identification

Leveraging cross-link modification events in CLIP-seq for motif discovery

Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells

MSI1 Promotes the Expression of the GBM Stem Cell Marker CD44 by Impairing miRNA-Dependent Degradation

MicroRNA-16 and microRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1

MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1.

Mining gene functional networks to improve mass-spectrometry-based protein identification

Molecular characterization of the C-3 DNA puff gene of Rhynchosciara americana.

Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit.

Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer

Musashi1: an RBP with versatile functions in normal and cancer stem cells

Over-represented sequences located on 3' UTRs are potentially involved in regulatory functions

Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity.

Poly(A)-binding protein positively affects YB-1 mRNA translation through specific interaction with YB-1 mRNA.

Post-transcription meets post-genomic: the saga of RNA binding proteins in a new era.

RIP-Chip analysis: RNA-Binding Protein Immunoprecipitation-Microarray (Chip) Profiling.

RNA binding protein HuR regulates the expression of ABCA1.

RNA processing as an alternative route to attack glioblastoma.

RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma

RNA-binding proteins to assess gene expression states of co-cultivated cells in response to tumor cells

Riborex: fast and flexible identification of differential translation from Ribo-seq data

Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line

Site identification in high-throughput RNA-protein interaction data

Switch in 3' splice site recognition between exon definition and splicing catalysis is important for sex-lethal autoregulation.

Synergism of Pro-neurogenic miRNAs Provides a More Effective Strategy to Target Glioma Stem Cells

The 3' end of the story: deciphering combinatorial interactions that control mRNA fate.

The Diverse Roles of RNA-Binding Proteins in Glioma Development

The RNA-Binding Protein Musashi1: A Major Player in Intestinal Epithelium Renewal and Colon Cancer Development ⬇️

The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation

The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells

Translation regulation gets its ‘omics’ moment ⬇️

Two-tiered approach identifies a network of cancer and liver disease-related genes regulated by miR-122.

Vascular biology and the sex of flies: regulation of vascular smooth muscle cell proliferation by wilms' tumor 1-associating protein.

WTAP is a novel oncogenic protein in acute myeloid leukemia

miR-124, -128, and -137 Orchestrate Neural Differentiation by Acting on Overlapping Gene Sets Containing a Highly Connected Transcription Factor Network.