List of works - Jonathan L Haines

Finding the missing heritability of complex diseases

scientific article

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

scientific article (publication date: 13 August 1993)

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

scientific article published on June 29, 1995

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

scientific article

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

Complement factor H variant increases the risk of age-related macular degeneration

scientific article (publication date: 15 April 2005)

Functional impact of global rare copy number variation in autism spectrum disorders

scientific article published on 15 July 2010

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

scientific article

Risk alleles for multiple sclerosis identified by a genomewide study

scientific article (publication date: 30 August 2007)

Common genetic variants on 5p14.1 associate with autism spectrum disorders

scientific article

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

scientific article

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

scientific article published on 29 September 2013

Seven new loci associated with age-related macular degeneration

scientific article

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

scientific article

Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1.

scientific article published on 15 February 2009

The genetic defect causing familial Alzheimer's disease maps on chromosome 21.

scientific article

Convergence of genes and cellular pathways dysregulated in autism spectrum disorders

scientific article

A genome-wide scan for common alleles affecting risk for autism

scientific journal article

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

scientific article

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

scientific article published on 21 December 2015

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

scientific article (2010)

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future

scientific article (publication date: October 2013)

Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis

scientific article

Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson Disease

scientific article (publication date: April 2003)

Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred

scientific article published on May 2002

Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease

scientific article

ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative

scientific article published in January 1997

Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes

scientific article

Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Head injury and the risk of AD in the MIRAGE study

scientific article

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

scientific article

The PhenX Toolkit: get the most from your measures

scientific article

Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record

scientific article

Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.

scientific article

Genetic linkage of bilateral acoustic neurofibromatosis to a DNA marker on chromosome 22

scientific article published in Nature

Individual common variants exert weak effects on the risk for autism spectrum disorders

scientific journal article

Age at onset in two common neurodegenerative diseases is genetically controlled

scientific article published on March 2002

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

scientific article published in September 1990

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

scientific article

Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma

scientific article

Isolation of a novel gene underlying Batten disease, CLN3. The International Batten Disease Consortium

scientific article

Analysis of European mitochondrial haplogroups with Alzheimer disease risk

scientific article

Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration

scientific article

Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis

scientific article published on 11 August 2006

Quality control procedures for genome-wide association studies

scientific article published in 2011

Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans

scientific article

Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation

scientific article published on 31 March 2008

List of works by Jonathan L Haines

Finding the missing heritability of complex diseases

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Complement factor H variant increases the risk of age-related macular degeneration

Functional impact of global rare copy number variation in autism spectrum disorders

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

Risk alleles for multiple sclerosis identified by a genomewide study

Common genetic variants on 5p14.1 associate with autism spectrum disorders

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

Seven new loci associated with age-related macular degeneration

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1.

The genetic defect causing familial Alzheimer's disease maps on chromosome 21.

Convergence of genes and cellular pathways dysregulated in autism spectrum disorders

A genome-wide scan for common alleles affecting risk for autism

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future

Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis

Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson Disease

Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred

Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease

ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative

Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes

Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Head injury and the risk of AD in the MIRAGE study

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

The PhenX Toolkit: get the most from your measures

Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record

Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.

Genetic linkage of bilateral acoustic neurofibromatosis to a DNA marker on chromosome 22

Individual common variants exert weak effects on the risk for autism spectrum disorders

Age at onset in two common neurodegenerative diseases is genetically controlled

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma

Isolation of a novel gene underlying Batten disease, CLN3. The International Batten Disease Consortium

Analysis of European mitochondrial haplogroups with Alzheimer disease risk

Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration

Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis

Quality control procedures for genome-wide association studies

Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans

Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation