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List of works by David A Reardon

3'-Deoxy-3'-[F-18]fluorothymidine positron emission tomography in patients with recurrent glioblastoma multiforme: comparison with Gd-DTPA enhanced magnetic resonance imaging

scientific article published in November 2006

A Pilot Study of IL-2Rα Blockade during Lymphopenia Depletes Regulatory T-cells and Correlates with Enhanced Immunity in Patients with Glioblastoma ⬇️

scientific article published on February 27, 2012

A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas ⬇️

scientific article published on August 24, 2012

A novel method for volumetric MRI response assessment of enhancing brain tumors

scientific article

A novel treatment for glioblastoma: integrin inhibition ⬇️

scientific article published on April 1, 2012

A novel, reproducible, and objective method for volumetric magnetic resonance imaging assessment of enhancing glioblastoma

scientific article

A phase 1 study of ABT-806 in subjects with advanced solid tumors

scientific article published on 17 April 2015

A phase I trial of the farnesyl transferase inhibitor, SCH 66336, with temozolomide for patients with malignant glioma

scientific article published on 7 July 2011

A phase II study evaluating the efficacy and safety of AMG 102 (rilotumumab) in patients with recurrent glioblastoma ⬇️

scientific article published on February 4, 2011

A phase II, multicenter trial of rindopepimut (CDX-110) in newly diagnosed glioblastoma: the ACT III study

scientific article

A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost

scientific article

A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma

scientific article

A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy

scientific article published on 21 February 2016

A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma

scientific article

A review of micro- and macrovascular analyses in the assessment of tumor-associated vasculature as visualized by MR.

scientific article

ACTR-17. EVOPHOSPHAMIDE (TH-302) FOR RECURRENT GBM FOLLOWING BEVACIZUMAB FAILURE, FINAL RESULTS OF A MULTICENTER PHASE II STUDY

ACTR-76. FINAL RESULTS FROM A PHASE I STUDY OF PLERIXAFOR AND BEVACIZUMAB IN RECURRENT HIGH-GRADE GLIOMA.

scientific article published on 6 November 2017

ACTR-93. A PHASE I STUDY OF MLN0128 (TAK-228) AND BEVACIZUMAB IN PATIENTS WITH ADVANCED SOLID TUMORS INCLUDING GLIOBLASTOMA

ACTR-95. HYPOXIA ACTIVATED EVOPHOSPHAMIDE (TH-302) FOR RECURRENT GBM FOLLOWING BEVACIZUMAB FAILURE, A MULTICENTER PHASE II STUDY

AT-36PANOBINOSTAT IN COMBINATION WITH BEVACIZUMAB FOR RECURRENT GLIOBLASTOMA AND ANAPLASTIC GLIOMA

AT-37PHASE I STUDY OF PLERIXAFOR AND BEVACIZUMAB IN RECURRENT HIGH-GRADE GLIOMA.

scientific article published in November 2014

AT-60A RANDOMIZED DOUBLE BLIND PLACEBO-CONTROLLED PHASE 2 TRIAL OF DENDRITIC CELL (DC) VACCINE ICT-107 FOLLOWING STANDARD TREATMENT IN NEWLY DIAGNOSED PATIENTS WITH GBM.

scientific article

ATCT-22NRG ONCOLOGY/RTOG 1122: PHASE II DOUBLE-BLINDED, PLACEBO-CONTROLLED STUDY OF BEVACIZUMAB WITH OR WITHOUT AMG 386 IN PATIENTS WITH RECURRENT GLIOBLASTOMA OR GLIOSARCOMA.

scientific article

ATIM-10. PHASE 2 TRIAL OF SL-701, A NOVEL IMMUNOTHERAPY COMPRISED OF SYNTHETIC SHORT PEPTIDES AGAINST GBM TARGETS IL-13Rα2, EphA2, AND SURVIVIN, IN ADULTS WITH SECOND-LINE RECURRENT GBM

ATNT-01ABT-414 MONO- OR COMBINATION THERAPY WITH TEMOZOLOMIDE (TMZ) RECHALLENGE IN PATIENTS WITH RECURRENT GLIOBLASTOMA (GBM) AND AMPLIFIED EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR): A PHASE I STUDY.

scientific article

ATNT-02DETERMINANTS OF RESPONSES AND RESISTANCE TO ABT-414: RESULTS OF NEXT-GENERATION SEQUENCING.

scientific article

ATNT-14PHASE I STUDY OF PLERIXAFOR AND BEVACIZUMAB IN RECURRENT HIGH-GRADE GLIOMA.

scientific article

ATNT-18A PHASE I STUDY OF MLN0128 AND BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA AND OTHER SOLID TUMORS.

scientific article

Abortion, mental health and charges of guilt by association ⬇️

scientific article published on March 1, 2012

Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme.

scientific article

Adjuvant radiation therapy, local recurrence, and the need for salvage therapy in atypical meningioma

scientific article

Adult Atypical Teratoid/Rhabdoid Tumors

scientific article

Advanced MRI assessment to predict benefit of anti-programmed cell death 1 protein immunotherapy response in patients with recurrent glioblastoma

scientific article published on 9 January 2017

Advances in malignant glioma drug discovery

scientific article published on 07 June 2011

Afatinib, an irreversible ErbB family blocker, with protracted temozolomide in recurrent glioblastoma: a case report

scientific article

An Update on the Role of Immunotherapy and Vaccine Strategies for Primary Brain Tumors

scientific article

An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme

scientific article

An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma ⬇️

scientific article published on June 1, 2013

Analysis of early hypertension and clinical outcome with bevacizumab: results from seven phase III studies

scientific article published on 13 March 2013

Angiogenesis inhibitors in tackling recurrent glioblastoma

scientific article

Antiangiogenic Therapy for Glioblastoma: The Challenge of Translating Response Rate into Efficacy ⬇️

scientific article published on January 1, 2013

Antiangiogenic therapy for glioblastoma: current status and future prospects

scientific article

Antitenascin-C monoclonal antibody radioimmunotherapy for malignant glioma patients

scientific article published on May 2007

Assessment of physical functioning in recurrent glioma: preliminary comparison of performance status to functional capacity testing

scientific article published on 11 February 2009

Barriers to Accrual and Enrollment in Brain Tumor Trials

scientific article published on 07 June 2019

Bevacizumab and daily temozolomide for recurrent glioblastoma

scientific article

Bevacizumab and glioblastoma: scientific review, newly reported updates, and ongoing controversies

scientific article published on 26 September 2014

Bevacizumab biosimilars: scientific justification for extrapolation of indications

scientific article published on 25 April 2018

Bevacizumab plus irinotecan in recurrent WHO grade 3 malignant gliomas

scientific article published on November 2008

Bevacizumab plus irinotecan in recurrent glioblastoma multiforme

scientific article published in October 2007

Bevacizumab therapy for adults with recurrent/progressive meningioma: a retrospective series

scientific article

Bevacizumab-induced reversible posterior leukoencephalopathy syndrome and successful retreatment in a patient with glioblastoma

scientific article published on 6 September 2011

Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial

scientific article published on 04 February 2019

Cancer: The nuances of therapy

scientific article published in March 2009

Changes in functional performance measures in adults undergoing chemoradiation for primary malignant glioma: a feasibility study

scientific article published on 18 May 2010

Checkpoint inhibition in meningiomas

scientific article published on June 2016

Chemotherapy and novel therapeutic approaches in malignant glioma

scientific article

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

scientific article

Cilengitide: a prototypic integrin inhibitor for the treatment of glioblastoma and other malignancies

scientific article published on December 2011

Cilengitide: an RGD pentapeptide ανβ3 and ανβ5 integrin inhibitor in development for glioblastoma and other malignancies

scientific article

Clinical experience with alpha-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6

scientific article

Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma

scientific article

Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas

scientific article published on September 2014

Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions

scientific article published on 13 April 2007

Colocalization of gadolinium-diethylene triamine pentaacetic acid with high-molecular-weight molecules after intracerebral convection-enhanced delivery in humans

scientific article

Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition.

scientific article

Computerized assessment of vessel morphological changes during treatment of glioblastoma multiforme: report of a case imaged serially by MRA over four years

scientific article published on 06 December 2008

Concepts for Immunotherapies in Gliomas.

scientific article

Current and future directions for Phase II trials in high-grade glioma ⬇️

scientific article published on April 1, 2013

Current available therapies and future directions in the treatment of malignant gliomas.

scientific article published on 13 July 2009

Current clinical development of PI3K pathway inhibitors in glioblastoma ⬇️

scientific article published on May 22, 2012

Current status of antiangiogenic therapies for glioblastomas

scientific article published on 10 December 2013

Dedication: Andrew T. Parsa

scientific article published in November 2015

Diagnosis and treatment of high-grade astrocytoma

scientific article

Diagnostic Accuracy of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy in Newly-Diagnosed Brain Mass and Suspected Recurrent Gliomas

scientific article published on 9 February 2018

Do statins, ACE inhibitors or sartans improve outcome in primary glioblastoma?

scientific article published on 8 February 2018

Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma

scientific article published on 19 January 2016

Dose-dense temozolomide regimens: antitumor activity, toxicity, and immunomodulatory effects

scientific article published on June 2010

Dosimetry and radiographic analysis of 131I-labeled anti-tenascin 81C6 murine monoclonal antibody in newly diagnosed patients with malignant gliomas: a phase II study.

scientific article

Effect of CYP3A-inducing anti-epileptics on sorafenib exposure: results of a phase II study of sorafenib plus daily temozolomide in adults with recurrent glioblastoma

scientific article

Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma

scientific article published on 28 August 2008

Everolimus tablets for patients with subependymal giant cell astrocytoma

scientific article published on August 2011

Exercise behavior, functional capacity, and survival in adults with malignant recurrent glioma

scientific article

Exercise interest and preferences among patients diagnosed with primary brain cancer

scientific article published on 4 July 2006

Experience with irinotecan for the treatment of malignant glioma

scientific article published on 10 September 2008

Exploring Predictors of Response to Dacomitinib in EGFR-Amplified Recurrent Glioblastoma

scientific article published on 08 June 2020

Extent of resection and overall survival for patients with atypical and malignant meningioma

scientific article published on 26 August 2015

Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas

scientific article published on 9 November 2016

Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model

scientific article published on 6 November 2015

Glioblastoma--more questions than answers?

scientific article published in February 2006

Glioma in 2014: unravelling tumour heterogeneity-implications for therapy

scientific article published on 06 January 2015

Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme

scientific article

Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma ⬇️

scientific article published on December 10, 2010

HOUT-28. OFF-LABEL USE OF PD-1 BLOCKADE WITH OR WITHOUT BEVACIZUMAB CONFERS ONLY LIMITED CLINICAL BENEFIT IN PATIENTS WITH RECURRENT HIGH-GRADE GLIOMA

High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas

scientific article published in June 2003

High-grade Gliomas

scientific article published in December 2017

Histogram analysis of apparent diffusion coefficient within enhancing and nonenhancing tumor volumes in recurrent glioblastoma patients treated with bevacizumab

scientific article

How treatment monitoring is influencing treatment decisions in glioblastomas

scientific article

Hypofractionated versus standard radiation therapy with or without temozolomide for older glioblastoma patients

scientific article published on April 2015

IDH1 and IDH2 mutations in gliomas

scientific article

IMCT-03SAFETY AND ACTIVITY OF NIVOLUMAB MONOTHERAPY AND NIVOLUMAB IN COMBINATION WITH IPILIMUMAB IN RECURRENT GLIOBLASTOMA: UPDATED RESULTS FROM CHECKMATE-143.

scientific article

IMCT-08ReACT: LONG-TERM SURVIVAL FROM A RANDOMIZED PHASE II STUDY OF RINDOPEPIMUT (CDX-110) PLUS BEVACIZUMAB IN RELAPSED GLIOBLASTOMA.

scientific article

IMCT-20ASSOCIATION OF SURVIVAL AND PROGRESSION-FREE SURVIVAL WITH IMMUNE RESPONSE IN HLA-A2+ NEWLY-DIAGNOSED GBM PATIENTS IN RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED PHASE 2 TRIAL OF DENDRITIC CELL (DC) IMMUNOTHERAPY WITH ICT-107.

scientific article

IMMUNE CHECKPOINT BLOCKADE FOR GLIOBLASTOMA: PRECLINICAL ACTIVITY OF SINGLE AGENT AND COMBINATORIAL THERAPY.

scientific article published in July 2014

INNV-13. ALLELE: A CONSORTIUM FOR PROSPECTIVE GENOMICS AND FUNCTIONAL DIAGNOSTICS TO GUIDE PATIENT CARE AND TRIAL ANALYSIS IN NEWLY-DIAGNOSED GLIOBLASTOMA

IT-02INITIATION OF CLINICAL STUDIES WITH SL-701, A SYNTHETIC MULTI-PEPTIDE VACCINE WITH ENHANCED IMMUNOSTIMULATORY PROPERTIES TARGETING MULTIPLE GLIOMA-ASSOCIATED ANTIGENS, IN ADULTS WITH FIRST RECURRENCE OF GLIOBLASTOMA.

scientific article published in November 2014

IT-28VACCINATION AGAINST EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT III IN GLIOBLASTOMA: THE RINDOPEPIMUT COMPASSIONATE USE EXPERIENCE.

scientific article published in November 2014

IT-29IMMUNE CHECKPOINT BLOCKADE FOR GLIOBLASTOMA: PRECLINICAL ACTIVITY OF SINGLE AGENT AND COMBINATORIAL THERAPY.

scientific article published in November 2014

Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma ⬇️

scientific article published on October 4, 2010

Immunomodulation for glioblastoma

scientific article

Immunotherapy against angiogenesis-associated targets: evidence and implications for the treatment of malignant glioma

scientific article published on May 2008

Immunotherapy for glioblastoma: going viral.

scientific article published in August 2018

Immunotherapy for glioblastoma: on the sidelines or in the game?

scientific article published in November 2017

Immunotherapy for neuro-oncology: the critical rationale for combinatorial therapy

scientific article

Immunotherapy response assessment in neuro-oncology: a report of the RANO working group

scientific article

Impact of imaging measurements on response assessment in glioblastoma clinical trials

scientific article

Incidence and patterns of neuraxis metastases in children with diffuse pontine glioma

scientific article published in April 2006

Incidence, risk factors, and reasons for hospitalization among glioblastoma patients receiving chemoradiation

scientific article

Incorporation of Biomarker Assessment in Novel Clinical Trial Designs: Personalizing Brain Tumor Treatments ⬇️

scientific article published on February 1, 2011

Induction of hyperintense signal on T2-weighted MR images correlates with infusion distribution from intracerebral convection-enhanced delivery of a tumor-targeted cytotoxin

scientific article published in March 2007

Interpretation of meta-analysis evaluating progression-free survival as a surrogate endpoint for overall survival in glioblastoma

scientific article published on 26 February 2015

Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors

scientific article published on 10 April 2008

Irinotecan: promising activity in the treatment of malignant glioma.

scientific article

Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG.

scientific article

Is there really a yin and yang to VEGF-targeted therapies?

scientific article published on 13 July 2010

It Is Time to Include Patients With Brain Tumors in Phase I Trials in Oncology ⬇️

scientific article published on July 18, 2011

Kluver-Bucy syndrome related to glioma.

scientific article published in July 2004

Knee deep in the nerve.

scientific article

Low-dose whole brain radiotherapy combined with radiosurgery for primary CNS lymphoma achieving partial response to induction methotrexate-based chemotherapy

scientific article published in January 2014

MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma

scientific article published on 9 May 2016

MNGO-01A PROGNOSTIC CYTOGENETIC SCORING SYSTEM TO GUIDE THE ADJUVANT MANAGEMENT OF PATIENTS WITH ATYPICAL MENINGIOMA.

scientific article

MNGO-04PHASE II TRIAL OF BEVACIZUMAB IN PATIENTS WITH SURGERY AND RADIATION REFRACTORY PROGRESSIVE MENINGIOMA.

scientific article

Mechanisms and therapeutic implications of hypermutation in gliomas

scientific article published on 15 April 2020

Medical management of brain tumors and the sequelae of treatment

scientific article

Mibefradil, a novel therapy for glioblastoma multiforme: cell cycle synchronization and interlaced therapy in a murine model ⬇️

scientific article published on October 20, 2012

Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade

scientific article published on 27 November 2018

Modeling tumor immunity of mouse glioblastoma by exhausted CD8+ T cells

scientific article published on 9 January 2018

Molecularly targeted therapy for malignant glioma

scientific article published on July 2007

Monoclonal antibodies for brain tumour treatment

scientific article published in September 2004

Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans ⬇️

scientific article published on July 18, 2011

Multicenter phase II study of rituximab and temozolomide in recurrent primary central nervous system lymphoma ⬇️

scientific article published on July 9, 2012

Multicentric Low-Grade Gliomas

scientific article

Multifocal anaplastic astrocytoma in a patient with hereditary colorectal cancer, transcobalamin II deficiency, agenesis of the corpus callosum, mental retardation, and inherited PMS2 mutation

scientific article

Multimodal MRI features predict isocitrate dehydrogenase genotype in high-grade gliomas

scientific article published on 26 June 2016

Multimodal imaging patterns predict survival in recurrent glioblastoma patients treated with bevacizumab.

scientific article published on 4 May 2016

NI-36VALIDATION OF RANO CRITERIA: CONTRIBUTION OF T2/FLAIR ASSESSMENT IN PATIENTS WITH RECURRENT GLIOBLASTOMA TREATED WITH BEVACIZUMAB.

scientific article published in November 2014

NIMG-16PSEUDOPROGRESSION AND IMMUNOTHERAPY IN GLIOBLASTOMA: A CASE SERIES FROM COHORT 1 OF CHECKMATE-143 (NCT02017717).

scientific article

NIMG-17CENTRAL NEUROPATHOLOGY REVIEW TO ASSIST IN THE EVALUATION OF IMMUNE-RELATED TREATMENT CHANGES VERSUS DISEASE PROGRESSION IN CHECKMATE-143.

scientific article

NIMG-18EVALUATING TUMOR PROGRESSION AND IMMUNOLOGIC REACTIONS DURING IMMUNOTHERAPY: NEUROIMAGING OBSERVATIONS FROM A MULTICENTER STUDY OF NIVOLUMAB MONOTHERAPY AND NIVOLUMAB IN COMBINATION WITH IPILIMUMAB IN RECURRENT GLIOBLASTOMA (CHECKMATE-143).

scientific article

NIMG-56IMMUNOTHERAPY RESPONSE ASSESSMENT IN NEURO-ONCOLOGY (iRANO): A REPORT OF THE RANO WORKING GROUP.

scientific article

NIMG-68. MRI CHANGES IN NEWLY DIAGNOSED GLIOBLASTOMA PATIENTS TREATED AS PART OF A PHASE II TRIAL WITH BAVITUXIMAB, RADIATION, AND TEMOZOLOMIDE

NIMG-98. ASSESSMENT OF TUMOR HYPOXIA AND PERFUSION IN GBM FOLLOWING BEV FAILURE USING FMISO 18F-PET AND MRI.

scientific article published on 6 November 2017

NRG/RTOG 1122: A phase 2, double-blinded, placebo-controlled study of bevacizumab with and without trebananib in patients with recurrent glioblastoma or gliosarcoma

scientific article published on 10 March 2020

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

article

Neuro-oncology in 2015: Progress in glioma diagnosis, classification and treatment

scientific article

Nivolumab with or without ipilimumab in patients with recurrent glioblastoma: results from exploratory phase 1 cohorts of CheckMate 143.

scientific article published on 28 October 2017

Novel human IgG2b/murine chimeric antitenascin monoclonal antibody construct radiolabeled with 131I and administered into the surgically created resection cavity of patients with malignant glioma: phase I trial results

scientific article

Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma

scientific article published on 28 January 2016

One size should not fit all: advancing toward personalized glioblastoma therapy

scientific article (publication date: June 2015)

Optimizing eligibility criteria and clinical trial conduct to enhance clinical trial participation for primary brain tumor patients

scientific article published on 24 January 2020

Outcome after bevacizumab clinical trial therapy among recurrent grade III malignant glioma patients

scientific article

Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy

scientific article

PATH-16. MOLECULAR PATHOLOGY AND CLINICAL CHARACTERISTICS OF MMR DEFICIENCY (MMRd) IN DIFFUSE GLIOMAS

PCV for anaplastic oligodendrogliomas: back to the future or a step backwards? A point/counterpoint discussion

scientific article

PD-1 inhibition has only limited clinical benefit in patients with recurrent high-grade glioma

scientific article published on 31 August 2018

PHASE II TRIAL OF THE PHOSPHATIDYINOSITOL-3 KINASE (PI3K) INHIBITOR BUPARLISIB (BKM120) IN RECURRENT GLIOBLASTOMA CONDUCTED BY THE IVY FOUNDATION EARLY PHASE CLINICAL TRIALS CONSORTIUM.

scientific article published in July 2014

Patterns of exercise across the cancer trajectory in brain tumor patients

scientific article published on May 2006

Pharmacokinetic drug interaction between AEE788 and RAD001 causing thrombocytopenia in patients with glioblastoma ⬇️

scientific article published on October 9, 2011

Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas

scientific article

Phase 1 trial of dasatinib plus erlotinib in adults with recurrent malignant glioma

scientific article published on 10 March 2012

Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma

scientific article

Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma

scientific article published on April 2004

Phase 1 trial of temozolomide plus irinotecan plus O6-benzylguanine in adults with recurrent malignant glioma

scientific article

Phase 2 and biomarker study of trebananib, an angiopoietin-blocking peptibody, with and without bevacizumab for patients with recurrent glioblastoma.

scientific article published on 19 December 2017

Phase 2 study of CT-322, a targeted biologic inhibitor of VEGFR-2 based on a domain of human fibronectin, in recurrent glioblastoma

scientific article

Phase 2 study of carboplatin, irinotecan, and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy

scientific article

Phase 2 study of dose-intense temozolomide in recurrent glioblastoma

scientific article

Phase 2 trial design in neuro-oncology revisited: a report from the RANO group

scientific article published on May 2012

Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma

scientific article published on April 2004

Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma

scientific article

Phase I and biomarker study of plerixafor and bevacizumab in recurrent high-grade glioma.

scientific article

Phase I pharmacokinetic study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor vatalanib (PTK787) plus imatinib and hydroxyurea for malignant glioma

scientific article published on May 2009

Phase I study of AEE788, a novel multitarget inhibitor of ErbB- and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients ⬇️

scientific article published on March 7, 2012

Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma

scientific article

Phase I study of temozolomide and escalating doses of oral etoposide for adults with recurrent malignant glioma

scientific article

Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma

scientific article published in October 2005

Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma

scientific article

Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma

scientific article

Phase I/II trial of vorinostat, bevacizumab, and daily temozolomide for recurrent malignant gliomas

scientific article published on 21 December 2017

Phase I/randomized phase II study of afatinib, an irreversible ErbB family blocker, with or without protracted temozolomide in adults with recurrent glioblastoma

scientific article published on 19 August 2014

Phase II Study of Bevacizumab and Vorinostat for Patients with Recurrent World Health Organization Grade 4 Malignant Glioma

scientific article published on 13 November 2017

Phase II Trial of Upfront Bevacizumab, Irinotecan, and Temozolomide for Unresectable Glioblastoma

scientific article published on 29 May 2015

Phase II study of Cloretazine for the treatment of adults with recurrent glioblastoma multiforme

scientific article

Phase II study of Gleevec plus hydroxyurea in adults with progressive or recurrent low-grade glioma

scientific article

Phase II study of Gleevec® plus hydroxyurea (HU) in adults with progressive or recurrent meningioma

scientific article published on 22 September 2011

Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients naive to antiangiogenic therapy

scientific article published on 14 August 2017

Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients with prior antiangiogenic therapy

scientific article published on 3 October 2017

Phase II study of carboplatin in children with progressive low-grade gliomas

scientific article

Phase II study of carboplatin, irinotecan, and bevacizumab for bevacizumab naïve, recurrent glioblastoma

scientific article

Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas

scientific article

Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme

scientific article

Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy

scientific article

Phase II study of monthly pasireotide LAR (SOM230C) for recurrent or progressive meningioma

scientific article

Phase II study of panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma

scientific article

Phase II trial of Gliadel plus O6-benzylguanine in adults with recurrent glioblastoma multiforme

scientific article published on February 2009

Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma

scientific article

Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma

scientific article published in February 2007

Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma

scientific article published on May 2002

Phase II trial of gefitinib in recurrent glioblastoma

scientific article published on 24 November 2003

Phase II trial of irinotecan plus celecoxib in adults with recurrent malignant glioma

scientific article published in January 2005

Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas

scientific article published in March 2002

Phase II trial of ponatinib in patients with bevacizumab-refractory glioblastoma

scientific article published on 24 August 2019

Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy

scientific article

Phase II trial of temozolomide in patients with progressive low-grade glioma

scientific article

Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma

scientific article

Phase II trial of triple tyrosine kinase receptor inhibitor nintedanib in recurrent high-grade gliomas

scientific article published on 22 October 2014

Phase II trial of upfront bevacizumab and temozolomide for unresectable or multifocal glioblastoma

scientific article published on 24 January 2013

Pitfalls in the neuroimaging of glioblastoma in the era of antiangiogenic and immuno/targeted therapy - detecting illusive disease, defining response

scientific article

Poor drug distribution as a possible explanation for the results of the PRECISE trial

scientific article published in August 2010

Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma

scientific article published on 24 July 2017

Programmed death ligand 1 (PD-L1) as an immunotherapy target in patients with glioblastoma

scientific article published on 10 May 2015

Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malig

scientific article published in October 2003

Progression-free survival as a surrogate endpoint for overall survival in glioblastoma: a literature-based meta-analysis from 91 trials

scientific article published on 12 December 2013

Proposed Response Assessment and Endpoints for Meningioma Clinical Trials: Report from the Response Assessment in Neuro-Oncology (RANO) Working Group

scientific article published on 01 January 2019

Prospects of immune checkpoint modulators in the treatment of glioblastoma

scientific article

QOL-07DESCRIPTION OF CLINICAL AND PATIENT REPORTED OUTCOMES ASSESSMENTS FROM A PHASE 3, MULTICENTER, RANDOMIZED TRIAL EVALUATING NIVOLUMAB MONOTHERAPY VERSUS BEVACIZUMAB IN RECURRENT GLIOBLASTOMA: CHECKMATE-143.

scientific article

Quantitative assessment of cardiorespiratory fitness, skeletal muscle function, and body composition in adults with primary malignant glioma

scientific article

Radiation therapy for glioblastoma: Executive summary of an American Society for Radiation Oncology Evidence-Based Clinical Practice Guideline

scientific article published on 31 March 2016

Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme

scientific article

Rapid Intraoperative Molecular Characterization of Glioma

scientific article published on 14 May 2015

Rare glial tumors

scientific article published on January 2016

Re-defining response and treatment effects for neuro-oncology immunotherapy clinical trials

scientific article published on 24 February 2015

Recent advances in the treatment of malignant astrocytoma

scientific article

Recurrent glioblastoma: volumetric assessment and stratification of patient survival with early posttreatment magnetic resonance imaging in patients treated with bevacizumab

scientific article published on 2 July 2013

Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial

scientific article published on 01 August 2019

Reply to F. Felix et al and M.F. Fay et al.

scientific article published on 13 June 2016

Report of the Jumpstarting Brain Tumor Drug Development Coalition and FDA clinical trials neuroimaging endpoint workshop (January 30, 2014, Bethesda MD).

scientific article

Retrospective study of carmustine or lomustine with bevacizumab in recurrent glioblastoma patients who have failed prior bevacizumab

scientific article

Ridaforolimus for patients with progressive or recurrent malignant glioma: a perisurgical, sequential, ascending-dose trial ⬇️

scientific article published on October 30, 2011

Rindopepimut vaccine and bevacizumab combination therapy: improving survival rates in relapsed glioblastoma patients?

scientific article published on 23 June 2015

SM-03A RANDOMIZED, PLACEBO-CONTROLLED PILOT TRIAL OF ARMODAFINIL FOR FATIGUE IN PATIENTS WITH GLIOMAS UNDERGOING RADIOTHERAPY.

scientific article published in November 2014

Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.

scientific article

Safety and efficacy of erlotinib in first-relapse glioblastoma: a phase II open-label study

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Safety and efficacy of stereotactic radiosurgery and adjuvant bevacizumab in patients with recurrent malignant gliomas

scientific article published on 12 April 2011

Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma

scientific article published on 21 March 2008

Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: phase II study results.

scientific article published in January 2006

Salvage re-irradiation for recurrent high-grade glioma and comparison to bevacizumab alone

scientific article published on 3 October 2017

Survival analysis of presumptive prognostic markers among oligodendrogliomas.

scientific article published in October 2005

Sustained radiographic and clinical response in patient with bifrontal recurrent glioblastoma multiforme with intracerebral infusion of the recombinant targeted toxin TP-38: case study

scientific article published on January 2005

Targeted alpha-particle radiotherapy with 211At-labeled monoclonal antibodies

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Targeted therapies: Further delineating bevacizumab's response spectrum.

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Targeting integrins in malignant glioma

scientific article published on 04 September 2010

Temozolomide in children with progressive low-grade glioma

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Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients

scientific article published on 11 March 2015

The Clinical Implications of Inconsistently Methylated Results from Glioblastoma MGMT Testing by Replicate Methylation-Specific PCR.

scientific article published on 14 September 2016

The Impact of T2/FLAIR Evaluation per RANO Criteria on Response Assessment of Recurrent Glioblastoma Patients Treated with Bevacizumab

scientific article published on 21 October 2015

The Neurologic Assessment in Neuro-Oncology (NANO) scale: a tool to assess neurologic function for integration into the Response Assessment in Neuro-Oncology (RANO) criteria

scientific article published in May 2017

The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, temozolomide, and irinotecan for newly diagnosed glioblastoma

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The development of dendritic cell vaccine-based immunotherapies for glioblastoma

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The emerging role of anti-angiogenic therapy for malignant glioma

scientific article published on 07 February 2008

The future of antiangiogenic treatment in glioblastoma

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Therapeutic advances in the treatment of glioblastoma: rationale and potential role of targeted agents

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Tinzaparin prophylaxis against venous thromboembolic complications in brain tumor patients

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Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma.

scientific article published on 6 March 2018

Treatment Options in Newly Diagnosed Glioblastoma ⬇️

scientific article published on June 1, 2013

Treatment of elderly patients with glioblastoma

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Treatment options and outcomes for glioblastoma in the elderly patient

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Treatment recommendations for primary extradural meningiomas

scientific article published on 07 September 2010

Tumor resection cavity administered iodine-131-labeled antitenascin 81C6 radioimmunotherapy in patients with malignant glioma: neuropathology aspects

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Ulceration of Striae distensae in high-grade glioma patients on concurrent systemic corticosteroid and bevacizumab therapy

scientific article

Update on bevacizumab and other angiogenesis inhibitors for brain cancer ⬇️

scientific article published on May 14, 2013

Update on the use of angiogenesis inhibitors in adult patients with brain tumors

scientific article published on May 2014

Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group

scientific article published on 15 March 2010

Using the theory of planned behavior to understand the determinants of exercise intention in patients diagnosed with primary brain cancer

scientific article published in March 2007

Vaccine-based immunotherapeutic approaches to gliomas and beyond

scientific article published on 12 May 2017

Validation of post-operative residual contrast enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma

scientific article published on 5 April 2018

Vascular endothelial growth factor targeted therapy in the perioperative setting: implications for patient care

scientific article published on 18 February 2010

Volumetric response quantified using T1 subtraction predicts long-term survival benefit from cabozantinib monotherapy in recurrent glioblastoma

scientific article

Voxel-Wise Analysis of Fluoroethyltyrosine PET and MRI in the Assessment of Recurrent Glioblastoma During Antiangiogenic Therapy

scientific article published on 17 October 2018

Will integrin inhibitors have proangiogenic effects in the clinic?

scientific article published in July 2009

ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors

scientific article published on November 2005

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