List of works by Georg Schett

12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis

scientific article published on 12 August 2009

12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance

scientific journal article

12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance

scientific article published on 23 November 2011

A Cytokine-Like Protein Dickkopf-Related Protein 3 Is Atheroprotective

scientific article

A Detailed Analysis of the Association between Urate Deposition and Erosions and Osteophytes in Gout

scientific article published on 21 September 2020

A Dual Role of Upper Zone of Growth Plate and Cartilage Matrix-Associated Protein in Human and Mouse Osteoarthritic Cartilage: Inhibition of Aggrecanases and Promotion of Bone Turnover

scientific article published on 13 January 2017

A RANKL G278R mutation causing osteopetrosis identifies a functional amino acid essential for trimer assembly in RANKL and TNF

scientific article published on 07 November 2011

A case report of plasma exchange, steroids, mycophenolate mofetil and cyclophosphamide in acquired factor VIII inhibitors

scientific article

A comparative analysis of magnetic resonance imaging and high-resolution peripheral quantitative computed tomography of the hand for the detection of erosion repair in rheumatoid arthritis.

scientific article published on 31 March 2015

A detailed comparative study of high-resolution ultrasound and micro-computed tomography for detection of arthritic bone erosions

scientific article published in May 2011

A typically atypical tenosynovitis

scientific article published on 27 June 2010

A10.17 Interleukin-36α is Expressed by Synovial Plasma Cells and Induces Cytokine Production in Human Fibroblasts

ACPA and bone loss in rheumatoid arthritis

scientific article published on October 2013

Abatacept blocks anti-citrullinated protein antibody and rheumatoid factor mediated cytokine production in human macrophages in IDO-dependent manner

scientific article published on 7 February 2018

Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer

scientific article published on 18 December 2016

Activating transcription factor 3 regulates canonical TGFβ signalling in systemic sclerosis.

scientific article

Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis

scientific article published on 24 October 2017

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

scientific article published on 13 March 2012

Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages

scientific article published on 11 March 2014

Activation of pregnane X receptor inhibits experimental dermal fibrosis

scientific article published on 4 January 2013

Acyltransferase skinny hedgehog regulates TGFβ-dependent fibroblast activation in SSc

scientific article published on 08 June 2019

Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY)

scientific article

Additive bone-protective effects of anabolic treatment when used in conjunction with RANKL and tumor necrosis factor inhibition in two rat arthritis models

scientific article published in May 2005

Additive effect of anti-citrullinated protein antibodies and rheumatoid factor on bone erosions in patients with RA.

scientific article

Adipokines in bone disease

scientific article published on 15 April 2016

Adult onset Still's disease associated with malignancy-Cause or coincidence?

scientific article published on 22 October 2015

Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint

scientific article published on 12 August 2014

Age- and Sex-Dependent Changes of Intra-articular Cortical and Trabecular Bone Structure and the Effects of Rheumatoid Arthritis

scientific article

Anaemia in inflammatory rheumatic diseases

scientific article

Analysis of periarticular bone changes in patients with cutaneous psoriasis without associated psoriatic arthritis

scientific article published on 4 February 2015

Analysis of the kinetics of osteoclastogenesis in arthritic rats

scientific article published in October 2005

Animal models for arthritis: innovative tools for prevention and treatment

scientific article published on 30 May 2011

Animal models of systemic sclerosis: prospects and limitations

scientific article published on October 2010

Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis

scientific article published on 01 January 2019

Anti-interleukin 6 receptor therapy as rescue treatment for giant cell arteritis.

scientific article published on 24 April 2011

Anti-tumour necrosis factor alpha therapy in patients with impaired renal function

scientific article published on 2 March 2007

Antiinflammatory effects of tumor necrosis factor on hematopoietic cells in a murine model of erosive arthritis

article

Antimodified protein antibody response pattern influences the risk for disease relapse in patients with rheumatoid arthritis tapering disease modifying antirheumatic drugs

scientific article published on 20 June 2016

Apremilast in psoriatic arthritis

scientific article published on 15 October 2015

Apremilast: a novel PDE4 inhibitor in the treatment of autoimmune and inflammatory diseases

scientific article published on October 2010

Are spondylarthritides related but distinct conditions or a single disease with a heterogeneous phenotype?

scientific article published on January 2013

Arthritis -- a nightmare for bone

scientific article

Arthritis and bone loss: a hen and egg story

scientific article published on January 2014

Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation

scientific article published on 9 February 2004

Association Between Vascular Cell Adhesion Molecule 1 and Atrial Fibrillation

scientific article published on 29 March 2017

Association of brain functional magnetic resonance activity with response to tumor necrosis factor inhibition in rheumatoid arthritis

scientific article published in February 2013

Autoantibody-mediated bone loss

scientific article published on March 2014

Autoimmunity as a trigger for structural bone damage in rheumatoid arthritis

scientific article published on 4 January 2017

Autoimmunity's next top models

scientific article published on 6 January 2012

Automated three-dimensional registration of high-resolution peripheral quantitative computed tomography data to quantify size and shape changes of arthritic bone erosions

scientific article

B-cell infiltrates induce endosteal bone formation in inflammatory arthritis.

scientific article published in October 2008

Binary Segmentation Masks Can Improve Intrasubject Registration Accuracy of Bone Structures in CT Images

article by Oleg Museyko et al published 5 March 2010 in Annals of Biomedical Engineering

Biochemical markers of ongoing joint damage in rheumatoid arthritis--current and future applications, limitations and opportunities

scientific article

Blockade of IL-36 receptor signaling does not prevent from TNF-induced arthritis

scientific article

Blockade of TNF-α rapidly inhibits pain responses in the central nervous system

scientific article

Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus

scientific article published on 10 February 2013

Bonding the foe - NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals

scientific article published on 10 December 2012

Bone anabolic changes progress in psoriatic arthritis patients despite treatment with methotrexate or tumour necrosis factor inhibitors

scientific article published on 21 August 2012

Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment

scientific article

Bone erosions and bone marrow edema as defined by magnetic resonance imaging reflect true bone marrow inflammation in rheumatoid arthritis

scientific article

Bone formation in psoriatic arthritis: a report from the GRAPPA 2013 Annual Meeting

scientific article published in June 2014

Bone formation versus bone resorption in ankylosing spondylitis.

scientific article published on January 2009

Bone marrow edema

scientific article

Bone mass, bone microstructure and biomechanics in patients with hand osteoarthritis

scientific article published on 12 May 2020

Bone research in 2012: the ups and downs of bone in health and rheumatic disease

scientific article published on 08 January 2013

Bone- and cartilage-protective effects of a monoclonal antibody against colony-stimulating factor 1 receptor in experimental arthritis.

scientific article published in November 2014

CD44 is a determinant of inflammatory bone loss

scientific article

COVID-19 revisiting inflammatory pathways of arthritis

scientific article published on 19 June 2020

Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells

scientific article published on July 2010

Cardiomyopathy in murine models of systemic sclerosis.

scientific article published in February 2015

Catabolic and anabolic periarticular bone changes in patients with rheumatoid arthritis: a computed tomography study on the role of age, disease duration and bone markers

scientific article

Cell-intrinsic NF-κB activation is critical for the development of natural regulatory T cells in mice

scientific article

Cells of the synovium in rheumatoid arthritis. Osteoclasts

scientific article published on January 2007

Cellular and molecular pathways of structural damage in rheumatoid arthritis

scientific article

Central nervous system effects of tumor necrosis factor alpha blockade

scientific article published on 23 November 2011

Changes in mechanical loading affect arthritis-induced bone loss in mice

scientific article published on 09 November 2019

Characterization and quantification of angiogenesis in rheumatoid arthritis in a mouse model using μCT.

scientific article

Checkpoint Inhibitors

article from 2019

Chronic skin inflammation leads to bone loss by IL-17-mediated inhibition of Wnt signaling in osteoblasts

scientific article

Churg-Strauss syndrome in childhood: a systematic literature review and clinical comparison with adult patients

scientific article published on 17 July 2008

Clinical and radiographic outcomes at 2 years and the effect of tocilizumab discontinuation following sustained remission in the second and third year of the ACT-RAY study

scientific article

Clinical, radiographic and immunogenic effects after 1 year of tocilizumab-based treatment strategies in rheumatoid arthritis: the ACT-RAY study

scientific article published on 28 January 2014

Combined inhibition of c-Abl and PDGF receptors for prevention and treatment of murine sclerodermatous chronic graft-versus-host disease

scientific article published on 31 August 2012

Combined inhibition of morphogen pathways demonstrates additive antifibrotic effects and improved tolerability.

scientific article

Combining functional magnetic resonance imaging with mouse genomics: new options in pain research

scientific article published in January 2010

Comparison of the effects of tocilizumab monotherapy and adalimumab in combination with methotrexate on bone erosion repair in rheumatoid arthritis

scientific article published on 29 May 2019

Coping strategies and depressiveness in primary systemic vasculitis--what is their impact on health-related quality of life?

scientific article

Correction: Differential Roles of MAPK Kinases MKK3 and MKK6 in Osteoclastogenesis and Bone Loss.

scientific article published on 16 January 2014

Correction: Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease

scientific article published on 20 February 2018

Cortical remodeling during menopause, rheumatoid arthritis, glucocorticoid and bisphosphonate therapy

scientific article published on 21 March 2013

Cytokines in the pathogenesis of rheumatoid arthritis

scientific article

Decreased quantity and quality of the periarticular and nonperiarticular bone in patients with rheumatoid arthritis: a cross-sectional HR-pQCT study

scientific article

Deficiency of Thrombospondin-4 in Mice Does Not Affect Skeletal Growth or Bone Mass Acquisition, but Causes a Transient Reduction of Articular Cartilage Thickness

scientific article published on 2 December 2015

Definition for Rheumatoid Arthritis Erosions Imaged with High Resolution Peripheral Quantitative Computed Tomography and Interreader Reliability for Detection and Measurement.

scientific article published in October 2016

Deletion of the receptor tyrosine kinase Tyro3 inhibits synovial hyperplasia and bone damage in arthritis

scientific article published on 30 April 2013

Depression, Anxiety, Resilience and Coping Pre and Post Kidney Transplantation - Initial Findings from the Psychiatric Impairments in Kidney Transplantation (PI-KT)-Study

scientific article published on 11 November 2015

Design of the tocilizumab in giant cell arteritis trial

scientific article published on 7 April 2013

Detection of "Candidatus Neoehrlichia mikurensis" in two patients with severe febrile illnesses: evidence for a European sequence variant

scientific article

Development of a Dual-Energy Computed Tomography Scoring System for Measurement of Urate Deposition in Gout

scientific article published on 16 October 2015

Development of three-dimensional prints of arthritic joints for supporting patients' awareness to structural damage

scientific article

Diabetes is an independent predictor for severe osteoarthritis: results from a longitudinal cohort study

scientific article published on 21 September 2012

Differences in bone structure between rheumatoid arthritis and psoriatic arthritis patients relative to autoantibody positivity.

scientific article published on 7 August 2013

Differential roles of MAPK kinases MKK3 and MKK6 in osteoclastogenesis and bone loss

scientific article

Differential tissue expression and activation of p38 MAPK alpha, beta, gamma, and delta isoforms in rheumatoid arthritis

scientific article published on September 2006

Differentially regulated expression of growth differentiation factor 5 and bone morphogenetic protein 7 in articular cartilage and synovium in murine chronic arthritis: potential importance for cartilage breakdown and synovial hypertrophy

scientific article

Differentiation of osteophyte types in osteoarthritis - proposal of a histological classification

scientific article published on 12 June 2015

Dipeptidylpeptidase 4 as a Marker of Activated Fibroblasts and a Potential Target for the Treatment of Fibrosis in Systemic Sclerosis

scientific article published on 01 January 2020

Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging

scientific article published on 21 July 2020

Does subclinical inflammation contribute to impairment of function of knee joints in aged individuals? High prevalence of ultrasound inflammatory findings

scientific article

Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis

scientific article published on 7 March 2008

EULAR definition of arthralgia suspicious for progression to rheumatoid arthritis

scientific article published on 6 October 2016

EULAR definition of difficult-to-treat rheumatoid arthritis

scientific article published on 01 October 2020

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

scientific article published on 2 March 2012

EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update

scientific article published on 01 June 2020

Early Changes of the Cortical Micro-Channel System in the Bare Area of the Joints of Patients With Rheumatoid Arthritis.

scientific article published on 10 May 2017

Early structural changes in cartilage and bone are required for the attachment and invasion of inflamed synovial tissue during destructive inflammatory arthritis.

scientific article published on 18 January 2012

Effects of Conventional Uric Acid-Lowering Therapy on Monosodium Urate Crystal Deposits

scientific article published on 10 December 2019

Effects of inflammatory and anti-inflammatory cytokines on the bone

scientific article published on 25 May 2011

Effects of targeted therapies on the bone in arthritides

scientific article published on 31 January 2017

Efficacy and safety of bimekizumab as add-on therapy for rheumatoid arthritis in patients with inadequate response to certolizumab pegol: a proof-of-concept study

scientific article published on 08 June 2019

Elevated Fra-1 expression causes severe lipodystrophy

scientific article published on 12 April 2011

Elevated serum levels of free interleukin-18 in adult-onset Still's disease.

scientific article published on 10 September 2016

Elevated serum levels of sonic hedgehog are associated with fibrotic and vascular manifestations in systemic sclerosis.

scientific article published on 11 May 2017

Endothelial progenitor cells: novel players in the pathogenesis of rheumatic diseases

scientific article

Entheses and bones in spondyloarthritis: 2008 Annual Research and Education Meeting of the Spondyloarthritis Research and Therapy Network (SPARTAN).

scientific article

Enthesitis: from pathophysiology to treatment

scientific article published in November 2017

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.

scientific article

Erosive arthritis

scientific article published in January 2007

Expression of adipokines in osteoarthritis osteophytes and their effect on osteoblasts.

scientific article published on 21 November 2016

Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis

scientific article published on 01 September 2020

Fra-2 Expression in Osteoblasts Regulates Systemic Inflammation and Lung Injury through Osteopontin

scholarly article by Yubin Luo published in November 2018

Fra-2 regulates B cell development by enhancing IRF4 and Foxo1 transcription.

scientific article published on 31 May 2017

Fra-2/AP-1 regulates melanoma cell metastasis by downregulating Fam212b

scientific article published on 13 November 2020

From bone biology to clinical outcome: state of the art and future perspectives

scientific article published on August 2010

Gadd45beta deficiency in rheumatoid arthritis: enhanced synovitis through JNK signaling

scientific article

Galectin-3 as a novel regulator of osteoblast-osteoclast interaction and bone homeostasis

scientific article

Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus

scientific article published on 11 July 2016

Glucocorticoid-induced relapse of COVID-19 in a patient with sarcoidosis

scientific article published on 30 June 2020

Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout

scientific article published on 9 September 2019

Guselkumab, a Selective Interleukin‐23 p19 Subunit Inhibitor, Resolves Dactylitis in Patients With Active Psoriatic Arthritis: Pooled Results Through Week 52 From Two Phase 3 Studies

scientific article published in 2023

Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis.

scientific article

Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis.

scientific article published in August 2012

Hereditary hemochromatosis as a risk factor for joint replacement surgery

scientific article published in July 2010

High degree of nonadherence to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis

scientific article published on 15 January 2015

High fat diet increases melanoma cell growth in the bone marrow by inducing osteopontin and interleukin 6

scientific article published on 30 March 2016

High incidence of disease recurrence after discontinuation of disease-modifying antirheumatic drug treatment in patients with psoriatic arthritis in remission.

scientific article published on 12 December 2013

High prevalence of tenosynovial inflammation before onset of rheumatoid arthritis and its link to progression to RA-A combined MRI/CT study.

scientific article published on 18 May 2016

High-resolution Quantitative Computed Tomography Demonstrates Structural Defects in Cortical and Trabecular Bone in IBD Patients

scientific article published on 27 January 2016

Hippocampal structure and function are maintained despite severe innate peripheral inflammation

scientific article published on 12 June 2015

How antirheumatic drugs protect joints from damage in rheumatoid arthritis

scientific article published on October 2008

How cytokine networks fuel inflammation: Toward a cytokine-based disease taxonomy

scientific article published on July 2013

How does joint remodeling work?: new insights in the molecular regulation of the architecture of joints

scientific article published on 10 April 2007

Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease

scientific article published on 17 January 2018

Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis

scientific article published on 21 April 2009

IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-alpha-mediated bone loss.

scientific article published on 22 April 2011

IVIg-mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1.

scientific article

Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis

scientific article

Imbalance of local bone metabolism in inflammatory arthritis and its reversal upon tumor necrosis factor blockade: direct analysis of bone turnover in murine arthritis

scientific article published on January 2006

Impaired periodontium and temporomandibular joints in tumour necrosis factor-α transgenic mice.

scientific article

Inactivation of autophagy ameliorates glucocorticoid-induced and ovariectomy-induced bone loss

scientific article published on 25 June 2015

Inactivation of evenness interrupted (EVI) reduces experimental fibrosis by combined inhibition of canonical and non-canonical Wnt signalling

scientific article published on 20 November 2013

Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling

scientific article published on 12 November 2012

Inactivation of the cannabinoid receptor CB1 prevents leukocyte infiltration and experimental fibrosis

scientific article published on November 2010

Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation

scholarly article by Mario M. Zaiss et al published 29 April 2010 in Arthritis and Rheumatism

Increased expression of CD154 and FAS in SLE patients' lymphocytes

scientific article published in December 2009

Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE

scientific article published on 08 December 2008

Induction of osteoclast-associated receptor, a key osteoclast costimulation molecule, in rheumatoid arthritis.

scientific article

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

scientific article published on 16 April 2012

Induction of sustained remission in early inflammatory arthritis with the combination of infliximab plus methotrexate: the DINORA trial

Inflammation-associated changes in bone homeostasis

scientific article published on June 2012

Inflammatory bone spur formation in psoriatic arthritis is different from bone spur formation in hand osteoarthritis

scientific article published in November 2014

Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice

scientific article published on 10 June 2013

Inflammatory osteolysis: a conspiracy against bone

scientific article published on June 2017

Influence of activating Fcgamma receptors on osteoclast differentiation and bone metabolism

Influence of antiTNF-alpha antibody treatment on fracture healing under chronic inflammation

scientific article

Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis

scientific article published on 21 August 2012

Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.

scientific article published in May 2012

Inhibition of bone remodeling in young mice by bisphosphonate displaces the plasma cell niche into the spleen.

scientific article

Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis.

scientific article

Inhibition of glycogen synthase kinase 3β induces dermal fibrosis by activation of the canonical Wnt pathway.

scientific article

Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo

scientific article

Inhibition of phosphodiesterase 4 (PDE4) reduces dermal fibrosis by interfering with the release of interleukin-6 from M2 macrophages

scientific article published on 16 February 2017

Inhibition of sumoylation prevents experimental fibrosis

scientific article published on 17 August 2012

Interaction between synovial inflammatory tissue and bone marrow in rheumatoid arthritis.

scientific article published in August 2005

Interleukin-1 function and role in rheumatic disease

scientific article

Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells ⬇️

scientific article published on April 1, 2011

Interleukin-6 receptor blockade induces limited repair of bone erosions in rheumatoid arthritis: a micro CT study

scientific article

I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss

scientific article

JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function

scientific article published on 01 February 2020

JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis.

scientific article

JAK1-dependent transphosphorylation of JAK2 limits the antifibrotic effects of selective JAK2 inhibitors on long-term treatment

scientific article published on 6 May 2017

JNK1 is not essential for TNF-mediated joint disease

scientific article

Jan Mikulicz-Radecki (1850-1905): return of the surgeon

scientific article published on 28 September 2020

Johann Lucas Schoenlein (1793-1864): impact without publications

scientific article published on 02 November 2020

Joint remodelling in inflammatory disease

scientific article published on November 2007

Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis.

scientific article

Key opinion leaders - a critical perspective

scientific article published on 30 November 2020

Lack of inhibitory effects of the anti-fibrotic drug imatinib on endothelial cell functions in vitro and in vivo

scientific article published in October 2009

Listeria-associated arthritis in a patient undergoing etanercept therapy: case report and review of the literature

scientific article

Long-Term Safety and Tolerability of Apremilast Versus Placebo in Psoriatic Arthritis: A Pooled Safety Analysis of Three Phase III, Randomized, Controlled Trials

scientific article published on 25 July 2020

Long-term Combination Therapy with Anti-TNF plus Vedolizumab Induces and Maintains Remission in Therapy-refractory Ulcerative Colitis

scientific article

Longterm (52-week) results of a phase III randomized, controlled trial of apremilast in patients with psoriatic arthritis

scientific article published on 15 January 2015

Low amounts of bisecting glycans characterize cerebrospinal fluid-borne IgG

scholarly article by Jasmin Knopf et al published July 2018 in Journal of Neuroimmunology

Major histocompatibility complex class II polymorphisms are associated with the development of anti-resorptive agent-induced osteonecrosis of the jaw.

scientific article published on 6 December 2012

Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis

scientific article published in August 2010

Massive nodulous lesions on hands and feet in a RA patient and improvement under baricitinib treatment

scientific article published on 01 November 2020

Mechanisms leading from systemic autoimmunity to joint-specific disease in rheumatoid arthritis

scientific article published on 15 December 2016

Mechanisms of Disease: the link between RANKL and arthritic bone disease

scientific article published on November 2005

Methods for segmentation of rheumatoid arthritis bone erosions in high-resolution peripheral quantitative computed tomography (HR-pQCT).

scientific article published on 23 September 2017

Micro-structural bone changes are associated with broad-spectrum autoimmunity and predict the onset of rheumatoid arthritis

scientific article published on 18 February 2020

Microparticles stimulate angiogenesis by inducing ELR(+) CXC-chemokines in synovial fibroblasts

scientific article published on April 2011

Mitogen-activated protein kinase 2 regulates physiological and pathological bone turnover

scientific article published in April 2013

MoMa from patients with systemic lupus erythematosus show altered adhesive activity

scientific article published in May 2009

Molecular mechanisms of inflammatory bone damage: emerging targets for therapy

scientific article published on 09 May 2008

Monosodium urate crystals induce extracellular DNA traps in neutrophils, eosinophils, and basophils but not in mononuclear cells

scientific article published on 3 September 2012

Moonlighting osteoclasts as undertakers of apoptotic cells

scientific article

Musculoskeletal disease burden of hereditary hemochromatosis

scholarly article by Enijad Sahinbegovic et al published 30 November 2010 in Arthritis and Rheumatism

NF-κB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-κB in immune-mediated diseases

scientific article published on 23 September 2013

Neutrophil Extracellular Traps Form a Barrier between Necrotic and Viable Areas in Acute Abdominal Inflammation

scientific article published on 10 October 2016

New insights in the mechanism of bone loss in arthritis

scientific article

New insights into the prevalence of depressive symptoms and depression in rheumatoid arthritis - Implications from the prospective multicenter VADERA II study.

scientific article published on 28 May 2019

Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis

scientific article published on 9 April 2015

Nintedanib macrophage activation and ameliorates vascular and fibrotic manifestations in the Fra2 mouse model of systemic sclerosis

scientific article

Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis

scientific article published on 30 March 2011

Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis

scientific article published on 12 January 2015

Osteitis and synovitis, but not bone erosion, is associated with proteoglycan loss and microstructure damage in the cartilage of patients with rheumatoid arthritis

scientific article published on 26 April 2013

OsteoRheumatology: a new discipline?

scientific article

Osteoarthritis research priorities: a report from a EULAR ad hoc expert committee

scientific article published on 13 March 2014

Osteoclast Differentiation Is Impaired in a Subgroup of SLE Patients and Correlates Inversely with Mycophenolate Mofetil Treatment

scientific article

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

scientific article

Osteoclasts and arthritis

scientific article published on July 2009

Osteoclasts are essential for TNF-alpha-mediated joint destruction

scientific article

Osteoimmunology in rheumatic diseases

scientific article published on 30 January 2009

Osteoprotegerin is a risk factor for progressive atherosclerosis and cardiovascular disease

scientific article published on 26 April 2004

Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice

scientific article published in July 2003

Overexpression of tumor necrosis factor causes bilateral sacroiliitis

scientific article published in March 2004

Oxidation of the alarmin high-mobility group box 1 protein (HMGB1) during apoptosis

scientific article published in May 2009

PGC-1α regulates autophagy to promote fibroblast activation and tissue fibrosis

scientific article published on 01 June 2020

PI3Kgamma regulates cartilage damage in chronic inflammatory arthritis

scientific article published on 4 September 2009

Palmar fasciitis and polyarthritis syndrome-systematic literature review of 100 cases

scientific article published on 06 March 2014

Paraneoplastic syndromes in rheumatology

scientific article

Pasteurella multocida Toxin Triggers RANKL-Independent Osteoclastogenesis

scientific article published on 27 February 2017

Pasteurella multocida toxin- induced osteoclastogenesis requires mTOR activation

scientific article published on 14 September 2015

Pathogenesis of Churg-Strauss syndrome: recent insights

scientific article published on May 2009

Pathogenesis of rheumatoid arthritis: targeting cytokines

scientific article

Pathogenetic insights from the treatment of rheumatoid arthritis

scientific article

Pathophysiology of new bone formation and ankylosis in spondyloarthritis

scientific article published on August 2012

Pathophysiology of subchondral bone erosions in rheumatoid arthritis

scientific article

Pathways for bone loss in inflammatory disease

scientific article published on June 2012

Patient-reported Health-related Quality of Life with apremilast for psoriatic arthritis: a phase II, randomized, controlled study

scientific article published on 15 April 2013

Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion

scientific article published on 24 July 2020

Patients with unstable angina pectoris show an increased frequency of the Fc gamma RIIa R131 allele

scientific article published on 20 June 2012

Periarticular Bone Loss in Arthritis Is Induced by Autoantibodies Against Citrullinated Vimentin.

scientific article published on 20 April 2017

Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling

scientific article

Pharmacotherapy: concepts of pathogenesis and emerging treatments. Novel targets in bone and cartilage

scientific article published on August 2010

Platelet-derived serotonin links vascular disease and tissue fibrosis

scientific article

Poly(ADP-ribose) polymerase-1 regulates fibroblast activation in systemic sclerosis

scientific article published on 3 February 2018

Polymorphisms in the Hsp70 gene locus are genetically associated with systemic lupus erythematosus

scientific article

Premature osteoarthritis as presenting sign of type II collagenopathy: a case report and literature review

scientific article published on 19 June 2012

Presence of HLA-B27 is associated with changes of serum levels of mediators of the Wnt and hedgehog pathway.

scientific article published on 19 October 2015

Prevalence of monosodium urate deposits in a population of rheumatoid arthritis patients with hyperuricemia

scientific article published on 2 December 2015

Pro-inflammatory cytokines in rheumatoid arthritis: pathogenetic and therapeutic aspects

scientific article

Prospective study on circulating MicroRNAs and risk of myocardial infarction

scientific article published on July 2012

Psychometric properties of three single-item pain scales in patients with rheumatoid arthritis seen during routine clinical care: a comparative perspective on construct validity, reproducibility and internal responsiveness

scientific article

Publisher Correction: Revisiting the gut-joint axis: links between gut inflammation and spondyloarthritis

scientific article published on 30 July 2020

Quantification and Impact of Secondary Osteoarthritis in Patients With Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis

scientific article published on 5 April 2016

Quantitative and Qualitative Changes of Bone in Psoriasis and Psoriatic Arthritis Patients

scientific article published on 31 March 2015

RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFalpha or anti-IL-1 therapies

scientific journal article

RANKL is a marker and mediator of local and systemic bone loss in two rat models of inflammatory arthritis

scientific article

RSK2 protects mice against TNF-induced bone loss.

scientific article published on 17 February 2012

Recombinant adenosine deaminase ameliorates inflammation, vascular disease and fibrosis in preclinical models of systemic sclerosis

scientific article published on 17 March 2020

Redox modulation of HMGB1-related signaling

scientific article published on 19 March 2013

Reduced Fluorescence versus Forward Scatter Time-of-Flight and Increased Peak versus Integral Fluorescence Ratios Indicate Receptor Clustering in Flow Cytometry

scientific article published on 29 May 2015

Registration of 2D histological sections with 3D micro-CT datasets from small animal vertebrae and tibiae

scientific article published on 19 August 2014

Regulatory T cells protect from local and systemic bone destruction in arthritis.

scientific article published on 17 May 2010

Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis

scientific article published on 04 November 2020

Relations of vitamin D status, gender and type 2 diabetes in middle-aged Caucasians

scientific article published on 22 May 2014

Remission in psoriatic arthritis-where are we now? ⬇️

scientific article published on 16 October 2017

Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus

scientific article published in June 2009

Repair of bone erosions in rheumatoid arthritis treated with tumour necrosis factor inhibitors is based on bone apposition at the base of the erosion.

scientific article published on 27 May 2011

Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis

scientific article

Reply to "Neutrophils are not required for resolution of acute gouty arthritis in mice".

scientific article

Reply to Hou: Central nervous system effects of TNF-α blockade.

scientific article published on 28 July 2011

Reply to: Osteoporosis: An Independent Determinant of Bone Erosions in Rheumatoid Arthritis?

scientific article published on 20 September 2017

Resolution of chronic inflammatory disease: universal and tissue-specific concepts

scientific article published in Nature Communications

Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells

scientific article

Response of human rheumatoid arthritis osteoblasts and osteoclasts to adiponectin

scientific article published on 5 January 2017

Response to peripheral immune stimulation within the brain: magnetic resonance imaging perspective of treatment success

scientific article

Response to: 'Correspondence on 'Glucocorticoid-induced relapse of COVID-19 in a patient with sarcoidosis'' by Jeny et al

scientific article published on 01 October 2020

Response to: 'Idiopathic inflammatory myopathies and antisynthetase syndrome: contribution of antisynthetase antibodies to improve current classification criteria' by Greco et al

scientific article published on 17 April 2019

Response to: 'Is the PET/CT first choice for differential diagnosis of FUO/IUO?' by Armagan et al.

scientific article

Response to: the value of 18(F)-FDG-PET/CT in identifying the cause of fever of unknown origin (FUO) and inflammation of unknown origin (IUO): data from a prospective study

scientific article published on 16 November 2017

Review: Immune cells and mediators of inflammatory arthritis

scientific article published on April 2008

Revisiting the gut-joint axis: links between gut inflammation and spondyloarthritis

scientific article published on 13 July 2020

Rheumatic paraneoplastic syndromes - A clinical link between malignancy and autoimmunity

scientific article

Rheumatoid arthritis therapy after tumor necrosis factor and interleukin-1 blockade

scientific article published on December 2003

Rheumatoid arthritis: inflammation and bone loss

scientific article

Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts

scientific article published in August 2008

Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine expression

scientific article published on 26 June 2009

Role of NOD1 polymorphism in susceptibility and clinical progression of rheumatoid arthritis

scientific article published on 25 January 2013

Running has a negative effect on bone metabolism and proinflammatory status in male aged rats

scientific article

SARS-CoV-2 vaccination responses in untreated, conventionally treated and anticytokine-treated patients with immune-mediated inflammatory diseases

scientific article published on 06 May 2021

Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis

scientific article published on 10 May 2013

Secukinumab provides rapid and sustained pain relief in psoriatic arthritis over 2 years: results from the FUTURE 2 study.

scientific article

Segmentation and quantification of bone erosions in high-resolution peripheral quantitative computed tomography datasets of the metacarpophalangeal joints of patients with rheumatoid arthritis

scientific article

Serum leptin level and the risk of nontraumatic fracture

scientific article published in December 2004

Similar Impact of Psoriatic Arthritis and Rheumatoid Arthritis on Objective and Subjective Parameters of Hand Function

scientific article published on 25 November 2020

Simultaneous quantification of bone erosions and enthesiophytes in the joints of patients with psoriasis or psoriatic arthritis - effects of age and disease duration.

scientific article

Sodium and potassium urate crystals differ in their inflammatory potential

scientific article published in May 2009

Soluble CD83 Triggers Resolution of Arthritis and Sustained Inflammation Control in IDO Dependent Manner

Soluble RANKL and risk of nontraumatic fracture

scientific article published on March 2004

Spondyloarthritis: may the force be with you?

scientific article published on 12 November 2013

Src kinases in systemic sclerosis: central roles in fibroblast activation and in skin fibrosis

scientific article published in May 2008

Stimulation of the soluble guanylate cyclase (sGC) inhibits fibrosis by blocking non-canonical TGFβ signalling.

scientific article published on 23 February 2014

Stimulators of soluble guanylate cyclase (sGC) inhibit experimental skin fibrosis of different aetiologies

scientific article published on 27 March 2015

Structural damage in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: traditional views, novel insights gained from TNF blockade, and concepts for the future

scientific article published on 25 May 2011

Structural damage progression in patients with early rheumatoid arthritis treated with methotrexate, baricitinib, or baricitinib plus methotrexate based on clinical response in the phase 3 RA-BEGIN study

scholarly article by Désirée van der Heijde et al published September 2018 in Clinical Rheumatology

Structural entheseal lesions in patients with psoriasis are associated with an increased risk of progression to psoriatic arthritis

scientific article published on 26 February 2020

Successful remission induction with a combination therapy of rituximab, cyclophosphamide, and steroids in a patient with refractory optic neuritis in Wegener’s granulomatosis ⬇️

scientific article published on September 23, 2010

Synovitis--an inflammation of joints destroying the bone

scientific article published on 15 October 2012

T cell costimulation molecules CD80/86 inhibit osteoclast differentiation by inducing the IDO/tryptophan pathway

scientific article published on May 2014

T cells as key players for bone destruction in gouty arthritis?

scientific article published on 2 December 2011

TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy

scientific article published on 20 July 2021

TNF and bone

scientific article published on 18 February 2010

TNF-induced structural joint damage is mediated by IL-1.

scholarly article

Tapering biologic and conventional DMARD therapy in rheumatoid arthritis: current evidence and future directions ⬇️

scientific article

Th2 and eosinophil responses suppress inflammatory arthritis

scientific article published on 07 June 2016

The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis

scientific article

The 12/15-lipoxygenase pathway promotes osteoclast development and differentiation

scientific article published in May 2009

The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells

scientific article

The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells

The Early Marginal Zone B Cell-Initiated T-Independent Type 2 Response Resists the Proteasome Inhibitor Bortezomib ⬇️

scientific article published on October 4, 2010

The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation

scientific article published on 14 April 2017

The Transient Chondrocyte Phenotype in Human Osteophytic Cartilage: A Role of Pigment Epithelium-Derived Factor?

scientific article

The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis

scientific article published on 22 May 2013

The controversial role of tumor necrosis factor alpha in fibrotic diseases

scientific article published on August 2008

The extracellular release of DNA and HMGB1 from Jurkat T cells during in vitro necrotic cell death

scientific article published on 16 February 2012

The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis

scientific article

The impact of coping strategies on mental and physical well-being in patients with rheumatoid arthritis

scientific article published in February 2012

The interaction of physical function and emotional well-being in rheumatoid arthritis--what is the impact on disease activity and coping?

scientific article published on 29 January 2013

The lonely death: chondrocyte apoptosis in TNF-induced arthritis

scientific article published in June 2007

The mitogen-activated protein kinase p38α regulates tubular damage in murine anti-glomerular basement membrane nephritis

scientific article

The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis

scientific article

The multiple faces of autoimmune-mediated bone loss

scientific article

The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis

scientific article published in November 2014

The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease

scientific article published on November 2006

The progression of cell death affects the rejection of allogeneic tumors in immune-competent mice - implications for cancer therapy

scientific article

The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus

scientific article

The revised Bristol Rheumatoid Arthritis Fatigue measures and the Rheumatoid Arthritis Impact of Disease scale: validation in six countries

scientific article

The rheumatoid arthritis-associated autoantigen hnRNP-A2 (RA33) is a major stimulator of autoimmunity in rats with pristane-induced arthritis

scientific article published in December 2007

The role of ACPAs in at-risk individuals: Early targeting of the bone and joints

scientific article published in February 2017

The role of Wnt proteins in arthritis

scientific article published on September 2008

The role of osteoprotegerin in arthritis

scientific article

The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes

scientific article

The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis.

scientific article published in January 2010

The transcription factor JunD mediates transforming growth factor {beta}-induced fibroblast activation and fibrosis in systemic sclerosis

scientific article published on 24 April 2011

The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis

scientific article published in Nature Communications

The value of (18)F-FDG-PET/CT in identifying the cause of fever of unknown origin (FUO) and inflammation of unknown origin (IUO): data from a prospective study

scientific article published on 19 September 2017

Therapeutic benefit of apremilast on enthesitis and dactylitis in patients with psoriatic arthritis: a pooled analysis of the PALACE 1–3 studies.

scientific article published on 27 June 2018

Toll-like receptor 2 is required for autoantibody production and development of renal disease in pristane-induced lupus

scientific article

Tophus resolution with pegloticase: a prospective dual-energy CT study

scientific article published on 17 June 2015

Towards a Computable Data Corpus of Temporal Correlations between Drug Administration and Lab Value Changes

scientific article

Treatment of psoriatic arthritis in a phase 3 randomised, placebo-controlled trial with apremilast, an oral phosphodiesterase 4 inhibitor

scientific article

Treatment of pulmonary fibrosis for twenty weeks with imatinib mesylate in a patient with mixed connective tissue disease

scientific article published in August 2008

Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of established fibrosis

scientific article

Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin

scientific article published in March 2002

Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo

scientific article

Tumour necrosis factor blockers and structural remodelling in ankylosing spondylitis: what is reality and what is fiction?

scientific article published on June 2007

Ucma is not necessary for normal development of the mouse skeleton

scientific article

Upper zone of growth plate and cartilage matrix associated protein protects cartilage during inflammatory arthritis.

scientific article

VCAM-1 serum levels are associated with arthropathy in hereditary haemochromatosis

scientific article published on 18 April 2013

Validation of Standardized Questionnaires Evaluating Symptoms of Depression in Rheumatoid Arthritis Patients: Approaches to Screening for a Frequent Yet Underrated Challenge

scientific article published on 2 August 2016

Validation of a radiographic scoring system for haemochromatosis arthropathy.

scientific article published on 2 August 2010

Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs

scientific article published on 20 September 2019

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis

scientific article

WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production

scientific article

What constitutes the fat signal detected by MRI in the spine of patients with ankylosing spondylitis? A prospective study based on biopsies obtained during planned spinal osteotomy to correct hyperkyphosis or spinal stenosis

scientific article published on 23 May 2019

Why does the gout attack stop? A roadmap for the immune pathogenesis of gout

scientific article

Wif-1 is expressed at cartilage-mesenchyme interfaces and impedes Wnt3a-mediated inhibition of chondrogenesis

scientific article published on 15 September 2009

Wnt inhibitory factor 1 deficiency uncouples cartilage and bone destruction in tumor necrosis factor α-mediated experimental arthritis

scientific article published in September 2013

Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis

scientific article published in July 2004

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

scientific article published on 10 February 2012

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