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List of works by Alice Rothnie

A comparison of SMA (styrene maleic acid) and DIBMA (di-isobutylene maleic acid) for membrane protein purification

scientific article published on 21 March 2020

AP-2-complex-mediated endocytosis of Drosophila Crumbs regulates polarity by antagonizing Stardust.

scientific article published on 2 November 2015

APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complex

scientific article

An Outward-Facing Aromatic Amino Acid Is Crucial for Signaling between the Membrane-Spanning and Nucleotide-Binding Domains of Multidrug Resistance Protein 1 (MRP1; ABCC1)

scientific article published on 05 July 2018

An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles.

scientific article published in June 2018

CD81 extracted in SMALP nanodiscs comprises two distinct protein populations within a lipid environment enriched with negatively charged headgroups

scientific article published on 28 July 2020

CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.

scientific article

Communication between the nucleotide binding domains of P-glycoprotein occurs via conformational changes that involve residue 508.

scientific article published on July 2003

Detergent-Free Membrane Protein Purification.

scientific article

Detergent-free purification of ABC (ATP-binding-cassette) transporters.

scientific article published on July 2014

Encapsulated membrane proteins: A simplified system for molecular simulation.

scientific article published on 2 March 2016

Expression and purification of recombinant G protein-coupled receptors: A review

scientific article published on 31 October 2019

Functional Expression of Multidrug Resistance Protein 4 MRP4/ABCC4

scientific article published on 05 August 2019

Hsc70-induced changes in clathrin-auxilin cage structure suggest a role for clathrin light chains in cage disassembly.

scientific article published on 20 June 2013

Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport.

scientific article published on 2 September 2008

Membrane protein extraction and purification using styrene-maleic acid (SMA) copolymer: effect of variations in polymer structure.

scientific article published on 30 September 2016

Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1).

scientific article published on 17 November 2008

Overcoming bottlenecks in the membrane protein structural biology pipeline

scientific article published on June 2016

Recombinant Membrane Protein Methods

scientific article published on 01 September 2018

Stabilization of Human Multidrug Resistance Protein 4 (MRP4/ABCC4) Using Novel Solubilization Agents

scientific article published on 05 August 2019

Structure and function of membrane proteins encapsulated in a polymer-bound lipid bilayer

scientific article published on 30 August 2017

The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment.

scientific article published on July 2005

The expression of P-glycoprotein does influence the distribution of novel fluorescent compounds in solid tumour models

scientific article published on October 20, 2003

The stabilisation of purified, reconstituted P-glycoprotein by freeze drying with disaccharides.

scientific article published on 17 October 2008

The synthesis of recombinant membrane proteins in yeast for structural studies

scientific article

The topography of transmembrane segment six is altered during the catalytic cycle of P-glycoprotein.

scientific article published on 10 June 2004

The yin and yang of solubilization and stabilization for wild-type and full-length membrane protein.

scientific article published on 22 February 2018

Towards understanding promiscuity in multidrug efflux pumps

scientific article published on 06 December 2013