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List of works by Christopher A Maxwell

A potential role for centrosomal deregulation within IgH translocation-positive myeloma

scientific article published on 01 January 2005

Anti-angiogenic treatment for breast cancer?

scientific article published on 09 March 2017

BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells

scientific article

Cell Cycle-dependent Tumor Engraftment and Migration are Enabled by Aurora A.

scientific article

Cell-surface and mitotic-spindle RHAMM: moonlighting or dual oncogenic functions?

scientific article published on April 2008

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

scientific article

FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning

scientific article published on 24 July 2019

Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical implications

scientific article published on 01 October 2003

Genetic interactions: the missing links for a better understanding of cancer susceptibility, progression and treatment.

scientific article published on 10 January 2008

Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition.

scientific article published on January 2013

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.

scientific article

HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development

scientific article published on 10 October 2017

Hyaluronan Mediated Motility Receptor (HMMR) Encodes an Evolutionarily Conserved Homeostasis, Mitosis, and Meiosis Regulator Rather than a Hyaluronan Receptor

scientific article published on 28 March 2020

Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.

scientific article

Hyaluronan-binding by CD44 reduces the memory potential of activated murine CD8 T cells.

scientific article published on 8 January 2018

In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression

scientific article published on 03 October 2002

Lymphagenesis and cancer metastasis.

scientific article published on July 1998

Modification of BRCA1-associated breast cancer risk by HMMR overexpression

scientific article published on 07 April 2022

Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients

scientific article

PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways

scientific article published on 15 March 2021

Pathogenic BRCA1 variants disrupt PLK1-regulation of mitotic spindle orientation

scientific article published on 22 April 2022

RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma.

scientific article

RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability

scientific article

Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity

scientific article

Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2

scientific article

TACC3-TSC2 maintains nuclear envelope structure and controls cell division.

scientific article published on 15 March 2010

Targeting tumour-initiating cells to improve the cure rates for triple-negative breast cancer.

scientific article published on 26 July 2010

The cytoskeletal protein RHAMM and ERK1/2 activity maintain the pluripotency of murine embryonic stem cells

scientific article

The non-motor adaptor HMMR dampens Eg5-mediated forces to preserve the kinetics and integrity of chromosome segregation.

scientific article published on 31 January 2018

The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma.

scientific article published on 10 December 2007

Tubers from patients with tuberous sclerosis complex are characterized by changes in microtubule biology through ROCK2 signalling.

scientific article published on 29 April 2014

Tumor Variant Identification That Accounts for the Unique Molecular Landscape of Pediatric Malignancies

scientific article published on 01 October 2018

YB-1 transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal-like breast cancer

scientific article