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List of works by Michael Milyavsky

A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal.

scientific article published on 8 July 2010

A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity

scientific article published on 31 January 2019

A novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype

scientific article

Amyloid-beta precursor-like protein APLP1 is a novel p53 transcriptional target gene that augments neuroblastoma cell death upon genotoxic stress.

scientific article published on 28 May 2007

An ERG Enhancer-Based Reporter Identifies Leukemia Cells with Elevated Leukemogenic Potential Driven by ERG-USP9X Feed-Forward Regulation

scientific article published on 07 June 2019

Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation.

scientific article published on 17 April 2018

Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53.

scientific article published on March 2001

DNA-damage response in hematopoietic stem cells: an evolutionary trade-off between blood regeneration and leukemia suppression.

scientific article published on 15 March 2017

Erratum: Replication stress in MLL-rearrangements.

scientific article published on 19 April 2016

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells

scientific article

Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth.

scientific article published in December 2003

Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect.

scientific article published in February 2007

Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells

scientific article published on 14 October 2020

Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling

scientific article published on 02 December 2013

Mutant p53 protects cells from 12-O-tetradecanoylphorbol-13-acetate-induced death by attenuating activating transcription factor 3 induction

scientific article published on November 2006

Myocardin in tumor suppression and myofibroblast differentiation.

scientific article published on 9 May 2007

Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype.

scientific article

Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.

scientific article published on 3 November 2016

Replication stress in MLL-rearrangements

scientific article

Replication stress in hematopoietic stem cells in mouse and man.

scientific article published on 18 October 2017

SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress

scientific article published on 6 February 2017

Spironolactone inhibits the growth of cancer stem cells by impairing DNA damage response

scientific article published on 08 January 2019

The murine telomerase catalytic subunit shares the PAb-240 mutant specific epitope of the p53 protein.

scientific article published on July 2003

The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA.

scientific article published in June 2002

The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation.

scientific article published on 18 October 2005

The role of the C' terminus of murine p53 in the p53/mdm-2 regulatory loop.

scientific article published in May 2001

Transcriptional programs following genetic alterations in p53, INK4A, and H-Ras genes along defined stages of malignant transformation

scientific article published on 01 June 2005

Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase.

scientific article

hTERT-immortalized prostate epithelial and stromal-derived cells: an authentic in vitro model for differentiation and carcinogenesis

scientific article

p53 is a regulator of macrophage differentiation.

scientific article published in April 2004

p53 mediates density-dependent growth arrest.

scientific article published on February 2004

p53 modulates base excision repair activity in a cell cycle-specific manner after genotoxic stress.

scientific article

p53-dependent down-regulation of telomerase is mediated by p21waf1.

scientific article published on 15 September 2004