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List of works by Jean-Christophe Francois

A hybrid CMV-H1 construct improves efficiency of PEI-delivered shRNA in the mouse brain.

scientific article published on 10 April 2007

A steric blocker of translation elongation inhibits IGF‐1R expression and cell transformation ⬇️

scientific article published on March 14, 2011

Alterations in tumorigenicity of embryonal carcinoma cells by IGF-I triple-helix induced changes in immunogenicity and apoptosis.

scientific article published in December 2000

Analytical biochemistry of DNA--protein assemblies from crude cell extracts.

scientific article published on 07 July 2007

Antisense anti IGF-I cellular therapy of malignant tumours: immune response in cancer patients

scientific article published on 04 March 2010

Chronodisruption in lung cancer and possible therapeutic approaches.

scientific article published on 27 August 2011

DNA enzymes as potential therapeutics: towards clinical application of 10-23 DNAzymes.

scientific article published on 14 March 2015

Disrupting IGF Signaling in Adult Mice Conditions Leanness, Resilient Energy Metabolism, and High Growth Hormone Pulses.

scientific article

Effect of competing self-structure on triplex formation with purine-rich oligodeoxynucleotides containing GA repeats ⬇️

scientific article published on June 11, 1995

Effective cleavage of structured RNAs by tandems of 10-23 DNAzymes with 3'-modified oligo(2'-O-methylribonucleotide)-effectors.

scientific article

Global quantitative analysis of protein expression and phosphorylation status in the liver of the medaka fish (Oryzias latipes) exposed to microcystin-LR I. Balneation study.

scientific article published on 30 October 2007

Global quantitative analysis of protein phosphorylation status in fish exposed to microcystin.

scientific article

Holo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway.

scientific article published on 28 August 2014

Inhibition of gene expression by anti-sense C-5 propyne oligonucleotides detected by a reporter enzyme

scientific article

Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction

scientific article

Modern tools for identification of nucleic acid-binding proteins.

scientific article published on 12 April 2008

Monitoring DNA triplex formation using multicolor fluorescence and application to insulin-like growth factor I promoter downregulation.

scientific article published on 27 January 2014

Periodic cleavage of poly(dA) by oligothymidylates covalently linked to the 1,10-phenanthroline-copper complex ⬇️

scientific article published on April 5, 1988

Proteomic and phosphoproteomic analysis of cellular responses in medaka fish (Oryzias latipes) following oral gavage with microcystin-LR.

scientific article

Small interfering RNA targeted to IGF-IR delays tumor growth and induces proinflammatory cytokines in a mouse breast cancer model

scientific article

Temporal variations in the dynamics of potentially microcystin-producing strains in a bloom-forming Planktothrix agardhii (Cyanobacterium) population.

scientific article published on 25 April 2008

The Alzheimer's disease transcriptome mimics the neuroprotective signature of IGF-1 receptor-deficient neurons.

scientific article

The approach of triple helix formation in control of gene expression and the treatment of tumors expressing IGF-I.

scientific article

The human DNA ends proteome uncovers an unexpected entanglement of functional pathways

scientific article

Unusual DNA conformations: implications for telomeres

scientific article

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