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List of works by Karl G. Wagner

A Rational Design of a Biphasic DissolutionSetup-Modelling of Biorelevant Kinetics for a Ritonavir Hot-Melt Extruded Amorphous Solid Dispersion

scientific article published on 06 March 2020

Amorphous solid dispersions of weak bases with pH-dependent soluble polymers to overcome limited bioavailability due to gastric pH variability - An in-vitro approach

scientific article published on 13 April 2019

Anion-induced water flux as drug release mechanism through cationic Eudragit RS 30D film coatings.

scientific article published on 24 October 2005

Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections

scientific article published on 07 December 2020

Development and Performance of a Highly Sensitive Model Formulation Based on Torasemide to Enhance Hot-Melt Extrusion Process Understanding and Process Development.

scientific article published on 27 February 2018

Development of matrix-based theophylline sustained-release microtablets

scientific article published on 01 January 2000

Dissolution enhancement of carbamazepine using twin-screw melt granulation

scientific article published on 16 January 2020

Evolution of a mini-scale biphasic dissolution model: Impact of model parameters on partitioning of dissolved API and modelling of in vivo-relevant kinetics.

scientific article published on 10 June 2016

From benchtop to pilot scale-experimental study and computational assessment of a hot-melt extrusion scale-up of a solid dispersion of dipyridamole and copovidone

scientific article published on 15 December 2017

Holistic QbD approach for hot-melt extrusion process design space evaluation: Linking materials science, experimentation and process modeling

scientific article published on 24 May 2019

Hot Melt Extrusion for Sustained Protein Release: Matrix Erosion and In Vitro Release of PLGA-Based Implants.

scientific article

Hydrophilic solutes in modified carbon dioxide extraction-prediction of the extractability using molecular dynamic simulation.

scientific article published on 14 April 2005

Impact of HPMCAS on the Dissolution Performance of Polyvinyl Alcohol Celecoxib Amorphous Solid Dispersions

scientific article published on 11 June 2020

Improvement of tabletability via twin-screw melt granulation: Focus on binder distribution

scientific article published on 28 August 2019

In vivo predictive mini-scale dissolution for weak bases: Advantages of pH-shift in combination with an absorptive compartment

scientific article published on 08 January 2014

Influence of PEG in PEG-PLGA microspheres on particle properties and protein release

scientific article published on 28 January 2012

Investigation of the pellet-distribution in single tablets via image analysis

scientific article published on 01 January 1999

Mechanistic study on hydrodynamics in the mini-scale biphasic dissolution model and its influence on in vitro dissolution and partitioning

scientific article published on 06 September 2018

Micro-scale prediction method for API-solubility in polymeric matrices and process model for forming amorphous solid dispersion by hot-melt extrusion.

scientific article published on 24 June 2016

Micro-scale solubility assessments and prediction models for active pharmaceutical ingredients in polymeric matrices

scientific article published on 14 May 2019

Modeling, design and manufacture of innovative floating gastroretentive drug delivery systems based on hot-melt extruded tubes

scientific article published on 28 February 2019

Novel ultrasonic in-die measurements during powder compression at production relevant speed

scientific article published on 14 October 2019

Numerical simulation of hot-melt extrusion processes for amorphous solid dispersions using model-based melt viscosity.

scientific article published on 5 December 2017

PROTAC-mediated crosstalk between E3 ligases

scientific article published on 01 February 2019

Predicting in vivo absorption behavior of oral modified release dosage forms containing pH-dependent poorly soluble drugs using a novel pH-adjusted biphasic in vitro dissolution test.

scientific article published on 22 May 2010

Predicting melt rheology for hot-melt extrusion by means of a simple Tg-measurement.

scientific article published on 19 May 2017

Prediction of solid fraction from powder mixtures based on single component compression analysis

scientific article published on 25 March 2017

Processing of Polyvinyl Acetate Phthalate in Hot-Melt Extrusion-Preparation of Amorphous Solid Dispersions

scientific article published on 09 April 2020

Quantification of the leaching of triethyl citrate/polysorbate 80 mixtures from Eudragit RS films by differential scanning calorimetry.

scientific article published on 12 January 2005

Rational development of solid dispersions via hot-melt extrusion using screening, material characterization, and numeric simulation tools.

scientific article

Site specific solubility improvement using solid dispersions of HPMC-AS/HPC SSL--mixtures

scientific article published on 21 April 2014

Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A

scientific article published on 18 November 2020

Tricalcium citrate - a new brittle tableting excipient for direct compression and dry granulation with enormous hardness yield

scientific article published on 04 July 2018

Validation of Model-Based Melt Viscosity in Hot-Melt Extrusion Numerical Simulation

scientific article

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