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List of works by Mirjam Zeisel

A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission

scientific article

A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses.

scientific article published on 29 July 2015

Acute hepatitis C virus infection induces anti-host cell receptor antibodies with virus-neutralizing properties

scientific article published on 23 May 2015

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors.

scientific article

Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles.

scientific article

CD81-receptor associations--impact for hepatitis C virus entry and antiviral therapies.

scientific article published on 18 February 2014

Cell Culture Models for the Investigation of Hepatitis B and D Virus Infection

scientific article published on 20 September 2016

Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps.

scientific article

Circulating microRNAs for early detection of hepatitis B-related hepatocellular carcinoma

scientific article published on June 2016

Claudins and pathogenesis of viral infection

scientific article published on 07 May 2015

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody

scientific article published on 23 March 2015

Clinical development of hepatitis C virus host-targeting agents.

scientific article published on 10 January 2017

Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of HCV-infected Cells and Liver to Identify Pathways Associated With Disease Development

scientific article published on 09 April 2019

Critical interaction between E1 and E2 glycoproteins determines binding and fusion properties of hepatitis C virus during cell entry.

scientific article published on 28 January 2014

Development of hepatitis C virus vaccines: challenges and progress.

scientific article

EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

scientific article published on 24 April 2011

ERK 1/2- and JNKs-dependent synthesis of interleukins 6 and 8 by fibroblast-like synoviocytes stimulated with protein I/II, a modulin from oral streptococci, requires focal adhesion kinase.

scientific article published on 20 May 2003

Epidermal growth factor receptor signaling impairs the antiviral activity of interferon-alpha

scientific article published on 5 September 2013

Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies.

scientific article published on 17 July 2013

Functional and Biochemical Characterization of Hepatitis C Virus (HCV) Particles Produced in a Humanized Liver Mouse Model

scientific article

Functional microRNA screen uncovers O-linked N-acetylglucosamine transferase as a host factor modulating hepatitis C virus morphogenesis and infectivity

scientific article published on 10 May 2019

Genotype 1 hepatitis C virus envelope features that determine antiviral response assessed through optimal covariance networks.

scientific article

HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response

scientific article published on 02 March 2019

HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex.

scientific article published on March 2013

Hepatitis B virus: is a cure possible?

scientific article published on 27 June 2016

Hepatitis C Virus-Induced Upregulation of MicroRNA miR-146a-5p in Hepatocytes Promotes Viral Infection and Deregulates Metabolic Pathways Associated with Liver Disease Pathogenesis.

scientific article published on 04 May 2016

Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents

scientific article (publication date: May 2014)

Hepatitis C virus entry: molecular mechanisms and targets for antiviral therapy

scientific article

Hepatitis C virus envelope glycoprotein signatures are associated with treatment failure and modulation of viral entry and neutralization.

scientific article published on 18 January 2013

Hepatitis C virus hypervariable region 1 modulates receptor interactions, conceals the CD81 binding site, and protects conserved neutralizing epitopes.

scientific article

Host cell responses induced by hepatitis C virus binding.

scientific article published on June 2006

Host neutralizing responses and pathogenesis of hepatitis C virus infection.

scientific article published on July 2008

Host-Targeting Agents to Prevent and Cure Hepatitis C Virus Infection

scientific article

Host-targeting agents for treatment of hepatitis B virus infection.

scientific article published on 08 August 2015

Host-targeting therapies for hepatitis C virus infection: current developments and future applications.

scientific article published on 21 March 2018

IFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapies

scientific article

Interferon-Induced Transmembrane Proteins Mediate Viral Evasion in Acute and Chronic Hepatitis C Virus Infection

scientific article published on 21 June 2019

MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin alpha5beta1

scientific article

Mutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies

scientific article published on 10 April 2012

Mutations within a conserved region of the hepatitis C virus E2 glycoprotein that influence virus-receptor interactions and sensitivity to neutralizing antibodies.

scientific article

Neutralizing host responses in hepatitis C virus infection target viral entry at postbinding steps and membrane fusion.

scientific article published on 22 July 2008

Opening the door for hepatitis C virus infection in genetically humanized mice.

scientific article published in November 2011

Plasmodium P36 determines host cell receptor usage during sporozoite invasion

scientific article

Production of infectious hepatitis C virus in tissue culture: a breakthrough for basic and applied research.

scientific article

Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C

scientific article

Reconstitution of the entire hepatitis C virus life cycle in nonhepatic cells.

scientific article

Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins

scientific article published on 20 August 2014

Scavenger Receptor Class B Is Required for Hepatitis C Virus Uptake and Cross-Presentation by Human Dendritic Cells

scientific article

Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81.

scientific article published on December 2007

Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes ⬇️

scientific article (publication date: 25 October 2016)

Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepatitis C.

scientific article

Synthetic anti-lipopolysaccharide peptides and hepatitis C virus infection ⬇️

scientific article published on 02 May 2013

Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma

scientific article published on 26 March 2020

The postbinding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination

scientific article

Toll-like receptor 2 senses hepatitis C virus core protein but not infectious viral particles

scientific article

Towards an HBV cure: state-of-the-art and unresolved questions--report of the ANRS workshop on HBV cure.

scientific article

Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment

scientific article published in 2023

Virus-host interactions during hepatitis C virus entry — implications for pathogenesis and novel treatment approaches

Virus-host interactions in hepatitis C virus infection: implications for molecular pathogenesis and antiviral strategies.

scientific article published on 25 May 2010

When one receptor closes, another opens: claudins and the hepatitis C virus E1 glycoprotein.

scientific article published on 30 April 2015

[Neutralizing antibodies in hepatitis C virus infection]

scientific article published on 07 May 2008

[Open Sesame: regulation of hepatitis C virus entry into hepatocytes]

scientific article published on 30 November 2011

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